CY1120767T1 - Συνθεσεις glp-1 πεπτιδιων και παρασκευη αυτων - Google Patents

Συνθεσεις glp-1 πεπτιδιων και παρασκευη αυτων

Info

Publication number
CY1120767T1
CY1120767T1 CY181101043T CY181101043T CY1120767T1 CY 1120767 T1 CY1120767 T1 CY 1120767T1 CY 181101043 T CY181101043 T CY 181101043T CY 181101043 T CY181101043 T CY 181101043T CY 1120767 T1 CY1120767 T1 CY 1120767T1
Authority
CY
Cyprus
Prior art keywords
glp
granules
compositions
peptye
preparation
Prior art date
Application number
CY181101043T
Other languages
English (en)
Inventor
Thomas Vilhelmsen
Helle Eliasen
Tue Hansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP13709231.8A external-priority patent/EP2827885B1/en
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of CY1120767T1 publication Critical patent/CY1120767T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Abstract

Η εφεύρεση αφορά φαρμακευτικές συνθέσεις που περιλαμβάνουν έναν πρώτο τύπο κόκκων και έναν δεύτερο τύπο κόκκων, όπου ο εν λόγω πρώτος τύπος κόκκων περιλαμβάνει ένα άλας του Ν-(8-(2-υδροξυβενζοϋλ)αμινο)καπρυλικού οξέος και όχι GLP-1 πεπτίδιο, και όπου ο εν λόγω δεύτερος τύπος κόκκων περιλαμβάνει ένα GLP-1 πεπτίδιο και όχι άλας του Ν-(8-(2-υδροξυβενζοϋλ)αμινο)καπρυλικού οξέος, όπως επίσης τους ενδιάμεσους κόκκους, μεθόδους για την παρασκευή των κόκκων και συνθέσεις και χρήση αυτών στην ιατρική.
CY181101043T 2012-03-22 2018-10-10 Συνθεσεις glp-1 πεπτιδιων και παρασκευη αυτων CY1120767T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP12160743 2012-03-22
US201361748840P 2013-01-04 2013-01-04
EP13153459 2013-01-31
EP13709231.8A EP2827885B1 (en) 2012-03-22 2013-03-15 Compositions of glp-1 peptides and preparation thereof
PCT/EP2013/055362 WO2013139694A1 (en) 2012-03-22 2013-03-15 Compositions of glp-1 peptides and preparation thereof

Publications (1)

Publication Number Publication Date
CY1120767T1 true CY1120767T1 (el) 2019-12-11

Family

ID=65910839

Family Applications (1)

Application Number Title Priority Date Filing Date
CY181101043T CY1120767T1 (el) 2012-03-22 2018-10-10 Συνθεσεις glp-1 πεπτιδιων και παρασκευη αυτων

Country Status (4)

Country Link
KR (1) KR102266299B1 (el)
CY (1) CY1120767T1 (el)
IL (1) IL234228B (el)
PT (1) PT2827885T (el)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI362392B (en) * 2005-03-18 2012-04-21 Novo Nordisk As Acylated glp-1 compounds
WO2008003050A2 (en) * 2006-06-28 2008-01-03 Emisphere Technologies, Inc. Gallium nitrate formulations
US20090124639A1 (en) * 2007-11-06 2009-05-14 Emisphere Technologies Inc. valacyclovir formulations
CA2734442C (en) * 2008-08-18 2016-08-16 Oramed Ltd Methods and compositions for oral administration of proteins
EP2566469B1 (en) * 2010-05-05 2022-12-21 Boehringer Ingelheim International GmbH Combination therapy
ES2952874T3 (es) * 2012-03-22 2023-11-06 Novo Nordisk As Composiciones de péptidos GLP-1 y preparación de estas

Also Published As

Publication number Publication date
IL234228B (en) 2019-03-31
PT2827885T (pt) 2018-11-05
KR20200013078A (ko) 2020-02-05
KR102266299B1 (ko) 2021-06-18

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