CY1120767T1 - GLP-1 PEPTYE COMPOSITIONS AND THEIR PREPARATION - Google Patents
GLP-1 PEPTYE COMPOSITIONS AND THEIR PREPARATIONInfo
- Publication number
- CY1120767T1 CY1120767T1 CY181101043T CY181101043T CY1120767T1 CY 1120767 T1 CY1120767 T1 CY 1120767T1 CY 181101043 T CY181101043 T CY 181101043T CY 181101043 T CY181101043 T CY 181101043T CY 1120767 T1 CY1120767 T1 CY 1120767T1
- Authority
- CY
- Cyprus
- Prior art keywords
- glp
- granules
- compositions
- peptye
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Η εφεύρεση αφορά φαρμακευτικές συνθέσεις που περιλαμβάνουν έναν πρώτο τύπο κόκκων και έναν δεύτερο τύπο κόκκων, όπου ο εν λόγω πρώτος τύπος κόκκων περιλαμβάνει ένα άλας του Ν-(8-(2-υδροξυβενζοϋλ)αμινο)καπρυλικού οξέος και όχι GLP-1 πεπτίδιο, και όπου ο εν λόγω δεύτερος τύπος κόκκων περιλαμβάνει ένα GLP-1 πεπτίδιο και όχι άλας του Ν-(8-(2-υδροξυβενζοϋλ)αμινο)καπρυλικού οξέος, όπως επίσης τους ενδιάμεσους κόκκους, μεθόδους για την παρασκευή των κόκκων και συνθέσεις και χρήση αυτών στην ιατρική.The invention relates to pharmaceutical compositions comprising a first type of granules and a second type of granules, wherein said first type of granules comprises an N- (8- (2-hydroxybenzoyl) amino) caprylic acid salt and not a GLP-1 peptide, and wherein said second type of granules comprises a GLP-1 peptide and not a salt of N- (8- (2-hydroxybenzoyl) amino) caprylic acid, as well as intermediate granules, methods for preparing granules and compositions and using them in medicine.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12160743 | 2012-03-22 | ||
US201361748840P | 2013-01-04 | 2013-01-04 | |
EP13153459 | 2013-01-31 | ||
PCT/EP2013/055362 WO2013139694A1 (en) | 2012-03-22 | 2013-03-15 | Compositions of glp-1 peptides and preparation thereof |
EP13709231.8A EP2827885B1 (en) | 2012-03-22 | 2013-03-15 | Compositions of glp-1 peptides and preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1120767T1 true CY1120767T1 (en) | 2019-12-11 |
Family
ID=65910839
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY181101043T CY1120767T1 (en) | 2012-03-22 | 2018-10-10 | GLP-1 PEPTYE COMPOSITIONS AND THEIR PREPARATION |
Country Status (4)
Country | Link |
---|---|
KR (1) | KR102266299B1 (en) |
CY (1) | CY1120767T1 (en) |
IL (1) | IL234228B (en) |
PT (1) | PT2827885T (en) |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI362392B (en) * | 2005-03-18 | 2012-04-21 | Novo Nordisk As | Acylated glp-1 compounds |
CA2656019C (en) * | 2006-06-28 | 2016-09-13 | Emisphere Technologies, Inc. | Gallium nitrate formulations |
US20090124639A1 (en) * | 2007-11-06 | 2009-05-14 | Emisphere Technologies Inc. | valacyclovir formulations |
AU2009283821B2 (en) * | 2008-08-18 | 2014-05-29 | Entera Bio Ltd. | Methods and compositions for oral administration of proteins |
BR112012028136A2 (en) * | 2010-05-05 | 2016-08-09 | Boehringer Ingelheim Int | combination therapy |
MY171146A (en) * | 2012-03-22 | 2019-09-27 | Novo Nordisk As | Compositions of glp-1 peptides and preparation thereof |
-
2013
- 2013-03-15 KR KR1020207002513A patent/KR102266299B1/en active IP Right Grant
- 2013-03-15 PT PT13709231T patent/PT2827885T/en unknown
-
2014
- 2014-08-21 IL IL234228A patent/IL234228B/en active IP Right Grant
-
2018
- 2018-10-10 CY CY181101043T patent/CY1120767T1/en unknown
Also Published As
Publication number | Publication date |
---|---|
PT2827885T (en) | 2018-11-05 |
KR102266299B1 (en) | 2021-06-18 |
IL234228B (en) | 2019-03-31 |
KR20200013078A (en) | 2020-02-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MY171146A (en) | Compositions of glp-1 peptides and preparation thereof | |
CY1120805T1 (en) | CRYSTAL FORMS SUSPENDER HYDROXYLASION PROYLO | |
CY1121225T1 (en) | CONCENTRATED IMIDAZOLYLIMIDAZOLS AS ANTIQUES | |
CY1119058T1 (en) | IMIDAZOPYRROLIDINONE COMPOUNDS | |
CY1120730T1 (en) | ORAL DOSAGE OF GLP-1 COMPOUNDS | |
EA201890123A1 (en) | NEW AMINO ACID DERIVATIVES, METHOD OF THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | |
EA201891099A1 (en) | 7- (TIAZOL-5-IL) Pyrrolopyrimide as an agonist of the TLR7 receptor | |
CY1121736T1 (en) | ARAMCHOL SALTS | |
EA201992133A1 (en) | PIPERIDINO-PYRIMIDINE DERIVATIVES FOR TREATMENT OF VIRAL INFECTIONS | |
CY1122483T1 (en) | MELPHALAN FLUFENAMIDE LYOPHYDRIED PRECAUTIONS | |
EA201401292A2 (en) | NEW THYENOPYRIMIDINE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | |
EA201391719A1 (en) | HINASOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES | |
EA201591166A1 (en) | AUTOTAXIN INHIBITORS | |
MX2013013913A (en) | Polypeptides. | |
EA201590343A1 (en) | ALKYLPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES | |
EA201590667A1 (en) | ACYLAMINOPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER DISEASES | |
EA201690246A1 (en) | AUTOTOXIN INHIBITORS CONTAINING A NUCLEAR HETEROAROMATIC RING-BENZYL-AMIDE CYCLE | |
EA201591751A1 (en) | TRIPEPTIDE EPOKEKETONE PROTEASE INHIBITORS | |
CY1121881T1 (en) | PHARMACEUTICAL FORM CONTAINING FIXED RATIO INSULIN GLARGINE/LIXISENATIDE | |
BR112015001327A2 (en) | 1-cyano-2- (4-cyclopropyl-benzyl) -4- (beta-d-glycopyran-1-yl) -benzene crystalline complex, methods for its preparation and use thereof to prepare medicaments | |
EA201791600A1 (en) | DERIVATIVES OF HYDROXIALKILPIPERASINE AS RECESSOR CXCR3 MODULATORS | |
BR112017013574A2 (en) | amino acid and peptide conjugates and uses thereof | |
UA116889C2 (en) | COMPOSITION COMPRISING A MIXTURE OF CD95-Fc ISOFORMS | |
MX2014004953A (en) | Tyrosine based linkers for the releasable connection of peptides. | |
EA201690390A1 (en) | AMIDO DERIVATIVES AS ANTAGONISTS OF A RECEPTOR FOR LYSOPHOSPHATIDIC ACID |