CY1113055T1 - Μεθοδοι θεραπειας δερματικης εξαψης χρησιμοποιωντας εκλεκτικους αγωνιστες αλφα-2-αδρενεργικου υποδοχεα - Google Patents

Μεθοδοι θεραπειας δερματικης εξαψης χρησιμοποιωντας εκλεκτικους αγωνιστες αλφα-2-αδρενεργικου υποδοχεα

Info

Publication number
CY1113055T1
CY1113055T1 CY20121100617T CY121100617T CY1113055T1 CY 1113055 T1 CY1113055 T1 CY 1113055T1 CY 20121100617 T CY20121100617 T CY 20121100617T CY 121100617 T CY121100617 T CY 121100617T CY 1113055 T1 CY1113055 T1 CY 1113055T1
Authority
CY
Cyprus
Prior art keywords
flushing
adreneric
receptors
alpha
methods
Prior art date
Application number
CY20121100617T
Other languages
English (en)
Inventor
Warren J Scherer
Original Assignee
Galderma Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Pharma S.A. filed Critical Galderma Pharma S.A.
Publication of CY1113055T1 publication Critical patent/CY1113055T1/el

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η παρούσα εφεύρεση αφορά στη μέθοδο θεραπείας, μείωσης, αναστολής, πρόληψης ή/και αναστροφής δερματικής έξαψης προσώπου που προκαλείται από μη φυσιολογική, ενδογενώς προκαλούμενης αγγειοκινητικής αστάθειας που σχετίζεται με, αλλά δεν περιορίζεται σε ροδόχρωμη ακμή, εξάψεις που σχετίζονται με εμμηνόπαυση, εξάψεις που είναι αποτέλεσμα ορχεκτομίας ή κατάποση ουσιών που είναι ικανές να προάγουν αντίδραση δερματικής έξαψης προσώπου (π.χ. αλκοόλη, σοκολάτα, μπαχαρικά), με τοπική δερματολογική εφαρμογή αποτελεσματικής δόσης σύνθεσης που περιλαμβάνει τουλάχιστον ένα αγωνιστή a2 αδρενεργικού υποδοχέα (όπως παράγωγο (2-ιμιδαζολιν-2-υλαμινο) κινοξαλίνης όπως τρυγική βριμονιδίνη) και κατάλληλο φορέα.
CY20121100617T 2003-07-23 2012-07-10 Μεθοδοι θεραπειας δερματικης εξαψης χρησιμοποιωντας εκλεκτικους αγωνιστες αλφα-2-αδρενεργικου υποδοχεα CY1113055T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/626,037 US20050020600A1 (en) 2003-07-23 2003-07-23 Methods of treating cutaneous flushing using selective alpha-2-adrenergic receptor agonists
EP20040778941 EP1789433B1 (en) 2003-07-23 2004-07-21 Methods of treating cutaneous flushing using selective alpha-2-adrenergic receptor agonists

Publications (1)

Publication Number Publication Date
CY1113055T1 true CY1113055T1 (el) 2016-04-13

Family

ID=34080324

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121100617T CY1113055T1 (el) 2003-07-23 2012-07-10 Μεθοδοι θεραπειας δερματικης εξαψης χρησιμοποιωντας εκλεκτικους αγωνιστες αλφα-2-αδρενεργικου υποδοχεα

Country Status (10)

Country Link
US (2) US20050020600A1 (el)
EP (2) EP1789433B1 (el)
CY (1) CY1113055T1 (el)
DK (1) DK1789433T3 (el)
ES (1) ES2386786T3 (el)
HK (1) HK1104308A1 (el)
PL (1) PL1789433T3 (el)
PT (1) PT1789433E (el)
SI (1) SI1789433T1 (el)
WO (1) WO2005010025A2 (el)

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Also Published As

Publication number Publication date
EP2481747A1 (en) 2012-08-01
US20050020600A1 (en) 2005-01-27
HK1104308A1 (en) 2008-01-11
PT1789433E (pt) 2012-07-24
SI1789433T1 (sl) 2012-09-28
DK1789433T3 (da) 2012-09-17
ES2386786T3 (es) 2012-08-30
WO2005010025A2 (en) 2005-02-03
PL1789433T3 (pl) 2012-10-31
EP1789433A2 (en) 2007-05-30
EP1789433A4 (en) 2010-08-18
WO2005010025A3 (en) 2006-03-23
EP1789433B1 (en) 2012-06-06
US20150031700A1 (en) 2015-01-29

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