CY1112166T1 - Παραγωγο αζολιου χρησιμο ως αντιμυκητιακοι παραγοντες με μειωμενη αλληλεπιδραση με μεταβολικα κυτοχρωματα - Google Patents

Παραγωγο αζολιου χρησιμο ως αντιμυκητιακοι παραγοντες με μειωμενη αλληλεπιδραση με μεταβολικα κυτοχρωματα

Info

Publication number
CY1112166T1
CY1112166T1 CY20101100539T CY101100539T CY1112166T1 CY 1112166 T1 CY1112166 T1 CY 1112166T1 CY 20101100539 T CY20101100539 T CY 20101100539T CY 101100539 T CY101100539 T CY 101100539T CY 1112166 T1 CY1112166 T1 CY 1112166T1
Authority
CY
Cyprus
Prior art keywords
useful
agents
antificial
azoli
producer
Prior art date
Application number
CY20101100539T
Other languages
English (en)
Inventor
Massimo Pinori
Maria Lattanzio
Daniela Modena
Paolo Mascagni
Original Assignee
Italfarmaco S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco S.P.A. filed Critical Italfarmaco S.P.A.
Publication of CY1112166T1 publication Critical patent/CY1112166T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Η παρούσα εφεύρεση αφορά νέες ενώσεις του γενικού τύπου (I), τις μορφές Ν-οξειδίου αυτών, τα άλατα αυτών με φαρμακευτικώς αποδεκτά οξέα και τα στερεοχημικά ισομερή αυτών, που είναι χρήσιμα ως αντιμυκητιακοί παράγοντες, φαρμακευτικές συνθέσεις που περιέχουν τέτοιες ενώσεις ως το δραστικό συστατικό, μεθόδους για την παραγωγή των εν λόγω ενώσεων και σχετικών φαρμακευτικών συνθέσεων.
CY20101100539T 2003-10-17 2010-06-11 Παραγωγο αζολιου χρησιμο ως αντιμυκητιακοι παραγοντες με μειωμενη αλληλεπιδραση με μεταβολικα κυτοχρωματα CY1112166T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT002020A ITMI20032020A1 (it) 2003-10-17 2003-10-17 Nuovi agenti antifungini azolici con diminuita interazione con i citocromi metabolici
EP04790506A EP1673368B1 (en) 2003-10-17 2004-10-14 Azole derivative useful as antifungal agents with reduced interaction with metabolic cytochromes

Publications (1)

Publication Number Publication Date
CY1112166T1 true CY1112166T1 (el) 2015-12-09

Family

ID=34509451

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100539T CY1112166T1 (el) 2003-10-17 2010-06-11 Παραγωγο αζολιου χρησιμο ως αντιμυκητιακοι παραγοντες με μειωμενη αλληλεπιδραση με μεταβολικα κυτοχρωματα

Country Status (17)

Country Link
US (1) US7427620B2 (el)
EP (1) EP1673368B1 (el)
JP (1) JP4744446B2 (el)
KR (1) KR101182740B1 (el)
CN (1) CN1867565B (el)
AT (1) ATE463493T1 (el)
BR (1) BRPI0415319A (el)
CA (1) CA2542361C (el)
CY (1) CY1112166T1 (el)
DE (1) DE602004026457D1 (el)
DK (1) DK1673368T3 (el)
ES (1) ES2344703T3 (el)
IT (1) ITMI20032020A1 (el)
PL (1) PL1673368T3 (el)
PT (1) PT1673368E (el)
SI (1) SI1673368T1 (el)
WO (1) WO2005040156A1 (el)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5963363B2 (ja) 2010-09-30 2016-08-03 国立大学法人 鹿児島大学 Ａｕｒｏｒａキナーゼプロモーターを含む増殖制御型ウイルスベクター

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3609596A1 (de) * 1986-03-21 1987-10-01 Hoechst Ag 2-azolylmethyl-2-aryl-1,3-dioxolane und deren salze, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung
EP0237693A1 (fr) 1986-03-21 1987-09-23 Ambrogio Catracchia Gicleur pour le nettoyage des dents et des appareils dentaires
US4788190A (en) * 1986-12-24 1988-11-29 Schering Corporation 2,4,4-tri- and 2,2,4,4-tetra substituted-1,3-dioxolane antifungal, antiallergy compounds
AU681753B2 (en) 1993-12-21 1997-09-04 Merck Sharp & Dohme Corp. Tetrahydrofuran antifungals
ATE273002T1 (de) 1996-06-28 2004-08-15 Schering Corp Feste lösung eines fungizids mit erhöhter bioverfügbarkeit
DE69824834T2 (de) 1997-02-11 2005-07-21 Janssen Pharmaceutica N.V. Azole enthaltende antifungale aminosäure-ester
EP0957101A1 (en) * 1998-05-14 1999-11-17 Janssen Pharmaceutica N.V. Water soluble azoles as broad-spectrum antifungals
FR2807434B1 (fr) * 2000-04-05 2002-10-18 Hoechst Marion Roussel Inc Nouveaux derives de la 1,2,3,4-tetrahydroisoquinoleine, leur procede de preparation et leur application comme fongicides

Also Published As

Publication number Publication date
ES2344703T3 (es) 2010-09-03
ITMI20032020A1 (it) 2005-04-18
DE602004026457D1 (de) 2010-05-20
BRPI0415319A (pt) 2006-12-05
PL1673368T3 (pl) 2010-09-30
US7427620B2 (en) 2008-09-23
CA2542361C (en) 2012-04-24
DK1673368T3 (da) 2010-06-07
KR101182740B1 (ko) 2012-09-13
ATE463493T1 (de) 2010-04-15
CA2542361A1 (en) 2005-05-06
SI1673368T1 (sl) 2010-08-31
US20070129376A1 (en) 2007-06-07
CN1867565B (zh) 2011-06-22
JP4744446B2 (ja) 2011-08-10
CN1867565A (zh) 2006-11-22
KR20060130554A (ko) 2006-12-19
WO2005040156A8 (en) 2005-06-23
EP1673368A1 (en) 2006-06-28
WO2005040156A1 (en) 2005-05-06
PT1673368E (pt) 2010-07-09
EP1673368B1 (en) 2010-04-07
JP2007533638A (ja) 2007-11-22

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CY1112166T1 (el) Παραγωγο αζολιου χρησιμο ως αντιμυκητιακοι παραγοντες με μειωμενη αλληλεπιδραση με μεταβολικα κυτοχρωματα
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