CY1112090T1 - Μεθοδος για ανιχνευση βιολογικων οργανισμων με χρηση σκεδασης raman - Google Patents

Μεθοδος για ανιχνευση βιολογικων οργανισμων με χρηση σκεδασης raman

Info

Publication number
CY1112090T1
CY1112090T1 CY20111100821T CY111100821T CY1112090T1 CY 1112090 T1 CY1112090 T1 CY 1112090T1 CY 20111100821 T CY20111100821 T CY 20111100821T CY 111100821 T CY111100821 T CY 111100821T CY 1112090 T1 CY1112090 T1 CY 1112090T1
Authority
CY
Cyprus
Prior art keywords
analyte
detecting biological
raman
organizations
screening
Prior art date
Application number
CY20111100821T
Other languages
English (en)
Inventor
Neal A Siegel
David R Fischell
Original Assignee
Sword Diagnostics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sword Diagnostics, Inc. filed Critical Sword Diagnostics, Inc.
Publication of CY1112090T1 publication Critical patent/CY1112090T1/el

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

Μέθοδος για την ανίχνευση ενώσεων, μεταξύ αυτών βιολογικών μακρομορίων και κυττάρων, με χρήση αλλαγών στις φασματοσκοπικές ιδιότητες Raman μετά από δέσμευση τουλάχιστον ενός εταίρου δέσμευσης προσδιοριζόμενης ουσίας. Η μέθοδος περιλαμβάνει την επαφή τουλάχιστον μίας προσδιοριζόμενης ουσίας με τουλάχιστον έναν εταίρο δέσμευσης προσδιοριζόμενης ουσίας, δέσμευση τουλάχιστον μίας προσδιοριζόμενης ουσίας σε τουλάχιστον έναν εταίρο δέσμευσης προσδιοριζόμενης ουσίας για το σχηματισμό συμπλέγματος, και ανίχνευση του συμπλέγματος με χρήση της αλλαγής της σκέδασης ακτινοβολίας Raman.
CY20111100821T 2005-10-17 2011-08-26 Μεθοδος για ανιχνευση βιολογικων οργανισμων με χρηση σκεδασης raman CY1112090T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72732805P 2005-10-17 2005-10-17
US83693606P 2006-08-11 2006-08-11
EP06816934A EP1946083B1 (en) 2005-10-17 2006-10-16 Method for detection of biological organisms using raman scattering

Publications (1)

Publication Number Publication Date
CY1112090T1 true CY1112090T1 (el) 2015-11-04

Family

ID=37771029

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100821T CY1112090T1 (el) 2005-10-17 2011-08-26 Μεθοδος για ανιχνευση βιολογικων οργανισμων με χρηση σκεδασης raman

Country Status (9)

Country Link
US (2) US7599057B2 (el)
EP (2) EP1946083B1 (el)
AT (1) ATE511636T1 (el)
CA (1) CA2628968C (el)
CY (1) CY1112090T1 (el)
DK (1) DK1946083T3 (el)
PL (1) PL1946083T3 (el)
PT (1) PT1946083E (el)
WO (1) WO2007047526A1 (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1946083B1 (en) * 2005-10-17 2011-06-01 Sword Diagnostics, Inc. Method for detection of biological organisms using raman scattering
US20100041016A1 (en) 2005-10-17 2010-02-18 Sword Diagnostics, Inc. Methods for detecting organisms and enzymatic reactions using raman spectroscopy and aromatic compounds comprising phosphate
US7947437B2 (en) 2005-10-17 2011-05-24 Sword Diagnostics, Inc. Methods for detecting organisms and enzymatic reactions using raman spectroscopy
CN101978248A (zh) * 2008-01-07 2011-02-16 动态通量生命科学仪器有限公司 具有整合微流化生物标记物光学检测阵列装置的发现工具和使用方法
US8547550B2 (en) * 2009-04-03 2013-10-01 Battelle Memorial Institute Biological and chemical collection and detection
US8279437B2 (en) 2010-07-14 2012-10-02 Hewlett-Packard Development Company, L.P. Multi-wavelength Raman light detection for detecting a species
US9662047B2 (en) 2010-08-05 2017-05-30 Massachusetts Institute Of Technology Portable raman diagnostic system
US20210003581A1 (en) * 2016-08-05 2021-01-07 The Texas A&M University System Immobilized substrate enzymatic surface enhanced raman spectroscopy (sers) assays
SG11202011970TA (en) 2018-08-27 2020-12-30 Regeneron Pharma Use of raman spectroscopy in downstream purification
CN113295672A (zh) * 2021-06-02 2021-08-24 上海海洋大学 基于表面增强拉曼光谱技术定量检测海水中碱性磷酸酶的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0714025A1 (en) 1994-11-25 1996-05-29 Kyoto Dai-ichi Kagaku Co., Ltd. Method of and apparatus for determining hydrogen peroxide by Raman scattering
US5741660A (en) 1995-02-01 1998-04-21 Kyoto Dai-Ichi Kagaku Co., Ltd. Method of measuring enzyme reaction by Raman scattering
JP2965502B2 (ja) 1996-02-20 1999-10-18 株式会社京都第一科学 表面増強ラマン散乱測定による分析方法
US5866430A (en) * 1996-06-13 1999-02-02 Grow; Ann E. Raman optrode processes and devices for detection of chemicals and microorganisms
US7267948B2 (en) * 1997-11-26 2007-09-11 Ut-Battelle, Llc SERS diagnostic platforms, methods and systems microarrays, biosensors and biochips
JP2000258346A (ja) 1999-03-08 2000-09-22 Arkray Inc ラマン分光法による基質の定量分析方法
EP1463926A4 (en) * 2002-01-10 2010-09-08 Chemimage Corp METHOD FOR DETECTING PATHOGENIC MICROORGANISMS
GB0216197D0 (en) 2002-07-12 2002-08-21 Univ Strathclyde Serrs active particles
US20060199209A1 (en) 2005-03-03 2006-09-07 Neal Arthur Siegel Enhanced detection of biological and bioactive components by resonance Raman spectroscopy
US20060216835A1 (en) 2005-03-24 2006-09-28 General Electric Company Method of separating unattached Raman-active tag from bioassay or other reaction mixture
WO2007011778A2 (en) 2005-07-18 2007-01-25 Parallax Biosystems Use of raman spectroscopy in enzyme activity assays
EP1946083B1 (en) 2005-10-17 2011-06-01 Sword Diagnostics, Inc. Method for detection of biological organisms using raman scattering
US7947437B2 (en) * 2005-10-17 2011-05-24 Sword Diagnostics, Inc. Methods for detecting organisms and enzymatic reactions using raman spectroscopy
ATE478559T1 (de) 2006-05-03 2010-09-15 Univ California Nachweis von protease und protease-aktivität mithilfe einer einzel-nanosteigerungs-sers-sonde

Also Published As

Publication number Publication date
PL1946083T3 (pl) 2012-04-30
US8243267B2 (en) 2012-08-14
WO2007047526A1 (en) 2007-04-26
PT1946083E (pt) 2011-09-13
CA2628968C (en) 2016-10-11
EP2264440A3 (en) 2011-10-19
ATE511636T1 (de) 2011-06-15
US7599057B2 (en) 2009-10-06
EP1946083B1 (en) 2011-06-01
EP1946083A1 (en) 2008-07-23
CA2628968A1 (en) 2007-04-26
EP2264440A2 (en) 2010-12-22
DK1946083T3 (da) 2011-09-19
US20100092942A1 (en) 2010-04-15
US20070087430A1 (en) 2007-04-19

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