CY1112023T1 - Φαρμακοτεχνικη μορφη νιτροοξυπαραγωγων των nsaids - Google Patents

Φαρμακοτεχνικη μορφη νιτροοξυπαραγωγων των nsaids

Info

Publication number
CY1112023T1
CY1112023T1 CY20111100026T CY111100026T CY1112023T1 CY 1112023 T1 CY1112023 T1 CY 1112023T1 CY 20111100026 T CY20111100026 T CY 20111100026T CY 111100026 T CY111100026 T CY 111100026T CY 1112023 T1 CY1112023 T1 CY 1112023T1
Authority
CY
Cyprus
Prior art keywords
nsaids
pharmaceutical form
formula
compound
cooh
Prior art date
Application number
CY20111100026T
Other languages
English (en)
Inventor
Ulla Gasslander
Christina Holmberg
Original Assignee
Nicox S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox S.A. filed Critical Nicox S.A.
Publication of CY1112023T1 publication Critical patent/CY1112023T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Η παρούσα εφεύρεση αφορά φαρμακοτεχνική μορφή περιλαμβάνουσα: α) ένα ή περισσότερα NSAID(s) απελευθέρωσης NO του τύπου (I), β) ένα ή περισσότερα επιφανειοδραστικά, γ) ένωση σαρωτή καρβονυλίου που επιλέγεται από μορφές ελευθέρου οξέος, άλατα, παράγωγα εστέρων καρβοξυλικού οξέος μιας ένωσης του τύπου (II): Η2Ν-(CH2)m-(C6H4)-COOH όπου το m = 0-10 και δ) προαιρετικά ένα έλαιο ή ημι-στερεό λίπος ή/και αλκοόλη βραχείας αλύσου.
CY20111100026T 2005-07-26 2011-01-07 Φαρμακοτεχνικη μορφη νιτροοξυπαραγωγων των nsaids CY1112023T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05106854 2005-07-26
EP06777502A EP1906938B1 (en) 2005-07-26 2006-06-29 Pharmaceutical formulation of nitrooxyderivatives of nsaids

Publications (1)

Publication Number Publication Date
CY1112023T1 true CY1112023T1 (el) 2015-11-04

Family

ID=37670077

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100026T CY1112023T1 (el) 2005-07-26 2011-01-07 Φαρμακοτεχνικη μορφη νιτροοξυπαραγωγων των nsaids

Country Status (25)

Country Link
US (1) US8691869B2 (el)
EP (1) EP1906938B1 (el)
JP (1) JP5238499B2 (el)
KR (1) KR101342910B1 (el)
CN (1) CN101227896B (el)
AR (1) AR055094A1 (el)
AT (1) ATE485033T1 (el)
AU (1) AU2006274098B2 (el)
CA (1) CA2616508C (el)
CY (1) CY1112023T1 (el)
DE (1) DE602006017701D1 (el)
DK (1) DK1906938T3 (el)
ES (1) ES2354278T3 (el)
HK (1) HK1120414A1 (el)
HR (1) HRP20110025T1 (el)
IL (1) IL188253A0 (el)
MX (1) MX2008001213A (el)
NO (1) NO20080983L (el)
NZ (1) NZ564589A (el)
PL (1) PL1906938T3 (el)
PT (1) PT1906938E (el)
RU (1) RU2406482C2 (el)
SI (1) SI1906938T1 (el)
WO (1) WO2007012539A2 (el)
ZA (1) ZA200801009B (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011209757A (ja) * 2011-07-06 2011-10-20 Rohto Pharmaceutical Co Ltd コンタクトレンズケア方法及び組成物
CA2827887C (en) * 2011-08-15 2020-06-09 Research Foundation Of The City University Of New York No- and h2s-releasing compounds
WO2013130625A1 (en) * 2012-02-27 2013-09-06 Basil Rigas Phospho-ester derivatives and uses thereof
RU2657803C1 (ru) * 2017-03-21 2018-06-15 федеральное государственное бюджетное образовательное учреждение высшего образования "Алтайский государственный университет" Средство, обладающее противовоспалительным и анальгезирующим действием

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997033568A1 (en) 1996-03-12 1997-09-18 Novartis Ag Filled gelatin capsules having a reduced degree of cross-linking
TWI243672B (en) * 1999-06-01 2005-11-21 Astrazeneca Ab New use of compounds as antibacterial agents
SE0000773D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0000774D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
NZ537022A (en) * 2002-06-05 2006-10-27 Ivax Pharmaceuticals S Reduction of gelatin cross-linking in the gelatin shell of gelatin capsules by incorporating a free amino acid into the capsule shall and a carboxylic acid ester into the capsule filling
BR0313064A (pt) * 2002-07-31 2005-06-28 Pharmacia Corp Forma de dosagem farmacêutica compreendendo um composto de sulfito

Also Published As

Publication number Publication date
JP2009502850A (ja) 2009-01-29
DE602006017701D1 (de) 2010-12-02
EP1906938B1 (en) 2010-10-20
US20090203759A1 (en) 2009-08-13
ATE485033T1 (de) 2010-11-15
NO20080983L (no) 2008-02-25
WO2007012539A2 (en) 2007-02-01
IL188253A0 (en) 2008-04-13
KR101342910B1 (ko) 2013-12-19
DK1906938T3 (da) 2011-02-07
CA2616508A1 (en) 2007-02-01
PT1906938E (pt) 2011-01-17
HRP20110025T1 (hr) 2011-03-31
AU2006274098B2 (en) 2012-02-09
RU2406482C2 (ru) 2010-12-20
JP5238499B2 (ja) 2013-07-17
CA2616508C (en) 2015-02-24
CN101227896A (zh) 2008-07-23
ZA200801009B (en) 2008-11-26
AR055094A1 (es) 2007-08-08
EP1906938A2 (en) 2008-04-09
CN101227896B (zh) 2013-02-06
PL1906938T3 (pl) 2011-05-31
AU2006274098A1 (en) 2007-02-01
KR20080028412A (ko) 2008-03-31
SI1906938T1 (sl) 2011-02-28
HK1120414A1 (en) 2009-04-03
RU2008104505A (ru) 2009-09-10
US8691869B2 (en) 2014-04-08
MX2008001213A (es) 2008-03-24
ES2354278T3 (es) 2011-03-11
WO2007012539A3 (en) 2007-04-19
NZ564589A (en) 2010-01-29

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