CY1112023T1 - Φαρμακοτεχνικη μορφη νιτροοξυπαραγωγων των nsaids - Google Patents

Φαρμακοτεχνικη μορφη νιτροοξυπαραγωγων των nsaids

Info

Publication number
CY1112023T1
CY1112023T1 CY20111100026T CY111100026T CY1112023T1 CY 1112023 T1 CY1112023 T1 CY 1112023T1 CY 20111100026 T CY20111100026 T CY 20111100026T CY 111100026 T CY111100026 T CY 111100026T CY 1112023 T1 CY1112023 T1 CY 1112023T1
Authority
CY
Cyprus
Prior art keywords
nsaids
pharmaceutical form
formula
compound
cooh
Prior art date
Application number
CY20111100026T
Other languages
English (en)
Inventor
Ulla Gasslander
Christina Holmberg
Original Assignee
Nicox S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox S.A. filed Critical Nicox S.A.
Publication of CY1112023T1 publication Critical patent/CY1112023T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Η παρούσα εφεύρεση αφορά φαρμακοτεχνική μορφή περιλαμβάνουσα: α) ένα ή περισσότερα NSAID(s) απελευθέρωσης NO του τύπου (I), β) ένα ή περισσότερα επιφανειοδραστικά, γ) ένωση σαρωτή καρβονυλίου που επιλέγεται από μορφές ελευθέρου οξέος, άλατα, παράγωγα εστέρων καρβοξυλικού οξέος μιας ένωσης του τύπου (II): Η2Ν-(CH2)m-(C6H4)-COOH όπου το m = 0-10 και δ) προαιρετικά ένα έλαιο ή ημι-στερεό λίπος ή/και αλκοόλη βραχείας αλύσου.
CY20111100026T 2005-07-26 2011-01-07 Φαρμακοτεχνικη μορφη νιτροοξυπαραγωγων των nsaids CY1112023T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05106854 2005-07-26
EP06777502A EP1906938B1 (en) 2005-07-26 2006-06-29 Pharmaceutical formulation of nitrooxyderivatives of nsaids

Publications (1)

Publication Number Publication Date
CY1112023T1 true CY1112023T1 (el) 2015-11-04

Family

ID=37670077

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100026T CY1112023T1 (el) 2005-07-26 2011-01-07 Φαρμακοτεχνικη μορφη νιτροοξυπαραγωγων των nsaids

Country Status (25)

Country Link
US (1) US8691869B2 (el)
EP (1) EP1906938B1 (el)
JP (1) JP5238499B2 (el)
KR (1) KR101342910B1 (el)
CN (1) CN101227896B (el)
AR (1) AR055094A1 (el)
AT (1) ATE485033T1 (el)
AU (1) AU2006274098B2 (el)
CA (1) CA2616508C (el)
CY (1) CY1112023T1 (el)
DE (1) DE602006017701D1 (el)
DK (1) DK1906938T3 (el)
ES (1) ES2354278T3 (el)
HK (1) HK1120414A1 (el)
HR (1) HRP20110025T1 (el)
IL (1) IL188253A0 (el)
MX (1) MX2008001213A (el)
NO (1) NO20080983L (el)
NZ (1) NZ564589A (el)
PL (1) PL1906938T3 (el)
PT (1) PT1906938E (el)
RU (1) RU2406482C2 (el)
SI (1) SI1906938T1 (el)
WO (1) WO2007012539A2 (el)
ZA (1) ZA200801009B (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011209757A (ja) * 2011-07-06 2011-10-20 Rohto Pharmaceutical Co Ltd コンタクトレンズケア方法及び組成物
CN103874488B (zh) * 2011-08-15 2018-03-20 纽约城市大学研究基金会 No‑和h2s‑释放化合物
US20130225529A1 (en) * 2012-02-27 2013-08-29 Basil Rigas Phospho-ester derivatives and uses thereof
RU2657803C1 (ru) * 2017-03-21 2018-06-15 федеральное государственное бюджетное образовательное учреждение высшего образования "Алтайский государственный университет" Средство, обладающее противовоспалительным и анальгезирующим действием

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1925697A (en) * 1996-03-12 1997-10-01 Novartis Ag Filled gelatin capsules having a reduced degree of cross-linking
TWI243672B (en) * 1999-06-01 2005-11-21 Astrazeneca Ab New use of compounds as antibacterial agents
SE0000774D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0000773D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
AU2003240536B2 (en) 2002-06-05 2007-11-15 Ivax Pharmaceuticals, S.R.O. Reduction of gelatin cross-linking
WO2004010974A2 (en) * 2002-07-31 2004-02-05 Pharmacia Corporation Gelatin capsule exhibiting reduced cross-linking

Also Published As

Publication number Publication date
IL188253A0 (en) 2008-04-13
ZA200801009B (en) 2008-11-26
MX2008001213A (es) 2008-03-24
KR101342910B1 (ko) 2013-12-19
ATE485033T1 (de) 2010-11-15
WO2007012539A3 (en) 2007-04-19
ES2354278T3 (es) 2011-03-11
KR20080028412A (ko) 2008-03-31
WO2007012539A2 (en) 2007-02-01
RU2406482C2 (ru) 2010-12-20
HRP20110025T1 (hr) 2011-03-31
JP2009502850A (ja) 2009-01-29
CN101227896A (zh) 2008-07-23
US8691869B2 (en) 2014-04-08
AU2006274098A1 (en) 2007-02-01
DE602006017701D1 (de) 2010-12-02
EP1906938A2 (en) 2008-04-09
PT1906938E (pt) 2011-01-17
AU2006274098B2 (en) 2012-02-09
DK1906938T3 (da) 2011-02-07
AR055094A1 (es) 2007-08-08
US20090203759A1 (en) 2009-08-13
NZ564589A (en) 2010-01-29
SI1906938T1 (sl) 2011-02-28
CA2616508C (en) 2015-02-24
EP1906938B1 (en) 2010-10-20
CA2616508A1 (en) 2007-02-01
JP5238499B2 (ja) 2013-07-17
CN101227896B (zh) 2013-02-06
PL1906938T3 (pl) 2011-05-31
HK1120414A1 (en) 2009-04-03
NO20080983L (no) 2008-02-25
RU2008104505A (ru) 2009-09-10

Similar Documents

Publication Publication Date Title
CY1119784T1 (el) Ακετυλιωμενες σαλικυλικες ενωσεις λιπαρου οξεος και οι χρησεις αυτων
ES2633317T3 (es) Compuestos y métodos para la modulación de quinasas, e indicaciones para ello
CO6382079A2 (es) Composiciones insecticidas estables a base de sulfoximina
EA200701810A1 (ru) Производное изоксазолина и новый способ его получения
UY31553A1 (es) Derivados herbicidas de piridazinona
NO20075068L (no) Lipocalinprotein
CY1113267T1 (el) Παραγωγα θειοφαινιου ως αγωνιστες των υποδοσεων s1p1/edg1
ATE442146T1 (de) Pharmazeutische zusammensetzung mit prostaglandin
CY1112023T1 (el) Φαρμακοτεχνικη μορφη νιτροοξυπαραγωγων των nsaids
RS53312B (en) TERNARY HERBICIDE COMPOSITIONS CONTAINING AMINOPYRALID AND IMAZAMOX
GT200500246A (es) Combinacion de compuestos organicos
RU2008139905A (ru) Фармацевтическая композиция для наружного применения
AR049681A1 (es) Macrolidos preparados a partir de actinomicetos. composiciones farmaceuticas
PE20081816A1 (es) Composiciones para bebidas comprendiendo polilisina y por lo menos un acido debil
AR074541A1 (es) Composiciones desinfectantes de plata naturales
EA200970124A1 (ru) Производные 2-арилиндола в качестве ингибиторов npges-1
RS52108B (en) 3-SUBSTITUTED [1,2,3] -BENZOTRIAZINONE UNIT TO INCREASE GLUTAMATERGIC SYNAPTIC ANSWERS
AR057174A1 (es) Mezclas
EA201100622A1 (ru) Солюбилизатор для ионов металлов
WO2007120725A3 (en) Pharmaceutical composition containing sympathomimetic amine salt and co-distillable additive
FR2925330B1 (fr) Utilisation d'un hydrolysat de pomme de terre en tant que principe actif activateur de la synthese des aquaporines
UY28375A1 (es) Agente terapéuticos
BR112012021108A2 (pt) composições biocidas, e, uso de valerolactona e/ou de seus derivados de amida
ATE365036T1 (de) Creatinester-pronutrient-verbindungen und formulierungen
RU2009138470A (ru) Композиция для наружного применения на коже