CY1109206T1 - gM- ΑΡΝΗΤΙΚΟΙ EHV-ΜΕΤΑΛΛΑΚΤΕΣ ΧΩΡΙΣ ΕΤΕΡΟΛΟΓΑ ΣΤΟΙΧΕΙΑ - Google Patents

gM- ΑΡΝΗΤΙΚΟΙ EHV-ΜΕΤΑΛΛΑΚΤΕΣ ΧΩΡΙΣ ΕΤΕΡΟΛΟΓΑ ΣΤΟΙΧΕΙΑ

Info

Publication number
CY1109206T1
CY1109206T1 CY20091100705T CY091100705T CY1109206T1 CY 1109206 T1 CY1109206 T1 CY 1109206T1 CY 20091100705 T CY20091100705 T CY 20091100705T CY 091100705 T CY091100705 T CY 091100705T CY 1109206 T1 CY1109206 T1 CY 1109206T1
Authority
CY
Cyprus
Prior art keywords
ehv
mutals
harterogical
information
viruses
Prior art date
Application number
CY20091100705T
Other languages
English (en)
Inventor
Antonie Neubauer
Christina Ziegler
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of CY1109206T1 publication Critical patent/CY1109206T1/el

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16061—Methods of inactivation or attenuation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Η παρούσα εφεύρεση αφορά το πεδίο ζωικής υγείας και συγκεκριμένα Ιούς Έρπη των Ίππων (EHV), όπου το γονίδιο που κωδικοποιεί την πρωτεΐνη gM απουσιάζει και το οποίο είναι ελεύθερο ετερόλογων στοιχείων. Περαιτέρω απόψεις της εφεύρεσης αφορούν φαρμακευτικές συνθέσεις που περιλαμβάνουν τους εν λόγω ιούς, χρήσεις αυτών και μεθόδους για την προφύλαξη και θεραπεία μολύνσεων EHV. Η εφεύρεση επίσης αφορά φαρμακευτικές συνθέσεις που περιλαμβάνουν το συνδυασμό EHV-1 και EHV-4 ιών, όπου το γονίδιο που κωδικοποιεί την πρωτεΐνη gM απουσιάζει και το οποίο είναι ελεύθερο ετερόλογων στοιχείων.
CY20091100705T 2002-07-19 2009-07-03 gM- ΑΡΝΗΤΙΚΟΙ EHV-ΜΕΤΑΛΛΑΚΤΕΣ ΧΩΡΙΣ ΕΤΕΡΟΛΟΓΑ ΣΤΟΙΧΕΙΑ CY1109206T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2002133064 DE10233064A1 (de) 2002-07-19 2002-07-19 gM-negative EHV-Mutanten ohne heterologe Elemente
EP20030765007 EP1539808B1 (en) 2002-07-19 2003-07-16 gM-NEGATIVE EHV-MUTANTS WITHOUT HETEROLOGOUS ELEMENTS

Publications (1)

Publication Number Publication Date
CY1109206T1 true CY1109206T1 (el) 2014-07-02

Family

ID=30010261

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100705T CY1109206T1 (el) 2002-07-19 2009-07-03 gM- ΑΡΝΗΤΙΚΟΙ EHV-ΜΕΤΑΛΛΑΚΤΕΣ ΧΩΡΙΣ ΕΤΕΡΟΛΟΓΑ ΣΤΟΙΧΕΙΑ

Country Status (17)

Country Link
EP (1) EP1539808B1 (el)
JP (2) JP4688491B2 (el)
KR (2) KR101167576B1 (el)
CN (4) CN101711864A (el)
AT (1) ATE427958T1 (el)
AU (1) AU2003258517B2 (el)
BR (1) BR0312787A (el)
CA (1) CA2493406C (el)
CY (1) CY1109206T1 (el)
DE (2) DE10233064A1 (el)
DK (1) DK1539808T3 (el)
ES (1) ES2324406T3 (el)
MX (1) MXPA05000592A (el)
PL (1) PL208225B1 (el)
PT (1) PT1539808E (el)
SI (1) SI1539808T1 (el)
WO (1) WO2004009802A2 (el)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1129722A1 (en) 2000-02-17 2001-09-05 Boehringer Ingelheim Vetmedica Gmbh gM-negative EHV-mutants
AR040601A1 (es) 2002-07-19 2005-04-13 Boehringer Ingelheim Vetmed Mutantes ehv negativos de gm sin elementos heterologos
CN101926560A (zh) * 2010-08-31 2010-12-29 苏州星岛金属制品有限公司 可伸缩的凳子
EA201990719A1 (ru) * 2016-09-20 2019-10-31 Новые промоторы
WO2023012331A1 (en) 2021-08-06 2023-02-09 Intervet International B.V. Vaccine for equine herpesvirus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6193983B1 (en) * 1992-06-01 2001-02-27 The University Of Melbourne Equine herpesvirus glycoproteins
EP1129722A1 (en) * 2000-02-17 2001-09-05 Boehringer Ingelheim Vetmedica Gmbh gM-negative EHV-mutants

Also Published As

Publication number Publication date
ATE427958T1 (de) 2009-04-15
CA2493406C (en) 2013-02-26
EP1539808A2 (en) 2005-06-15
ES2324406T3 (es) 2009-08-06
KR20050055689A (ko) 2005-06-13
WO2004009802A2 (en) 2004-01-29
MXPA05000592A (es) 2005-04-28
JP2005532819A (ja) 2005-11-04
JP2010057512A (ja) 2010-03-18
PT1539808E (pt) 2009-05-21
WO2004009802A3 (en) 2005-04-21
PL374574A1 (en) 2005-10-31
KR101167576B1 (ko) 2012-08-01
KR101111998B1 (ko) 2012-02-15
CN101712949B (zh) 2013-07-03
JP5469444B2 (ja) 2014-04-16
BR0312787A (pt) 2005-05-03
CN1668736A (zh) 2005-09-14
CN101711864A (zh) 2010-05-26
DE10233064A1 (de) 2004-02-05
JP4688491B2 (ja) 2011-05-25
CA2493406A1 (en) 2004-01-29
CN102978168A (zh) 2013-03-20
DK1539808T3 (da) 2009-07-27
EP1539808B1 (en) 2009-04-08
AU2003258517A1 (en) 2004-02-09
DE60327082D1 (de) 2009-05-20
AU2003258517B2 (en) 2009-05-07
CN101712949A (zh) 2010-05-26
SI1539808T1 (sl) 2009-08-31
KR20110007629A (ko) 2011-01-24
PL208225B1 (pl) 2011-04-29

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