CY1105741T1 - Μεθοδος παρασκευης 2-χλωροτριφαινυλομεθυλοχλωριδιου συνδεδεμενου με πολυμερικη μητρα - Google Patents

Μεθοδος παρασκευης 2-χλωροτριφαινυλομεθυλοχλωριδιου συνδεδεμενου με πολυμερικη μητρα

Info

Publication number
CY1105741T1
CY1105741T1 CY20061101557T CY061101557T CY1105741T1 CY 1105741 T1 CY1105741 T1 CY 1105741T1 CY 20061101557 T CY20061101557 T CY 20061101557T CY 061101557 T CY061101557 T CY 061101557T CY 1105741 T1 CY1105741 T1 CY 1105741T1
Authority
CY
Cyprus
Prior art keywords
preparing
linked
polymer matrix
chlorotriphenylmethyl
chlorotriphenylmethyl chloride
Prior art date
Application number
CY20061101557T
Other languages
English (en)
Inventor
Carsten Meininghaus
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of CY1105741T1 publication Critical patent/CY1105741T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/18—Introducing halogen atoms or halogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Lining Or Joining Of Plastics Or The Like (AREA)

Abstract

Περιγράφεται μια μέθοδος παρασκευής συνδεδεμένου με πολυμερική μήτρα 2-χλωροτριφαινυλομεθυ-λοχλωριδίου του τύπου (I), όπου Ρ είναι ένας πολυμερικός φορέας, κατά προτίμηση διαδικτυωμένο πολυστυρόλιο, μέσω αντίδρασης αντίστοιχου εστέρα (καρβονικού οξέος) με υδροχλώριο. Η μέθοδος επιτρέπει την επαναχρησιμοποίηση του μετά τη διάσπαση του πεπτιδίου προκύπτοντος φορέα ρητίνης της στερεής-φάσης-σύνθεσης πεπτιδίων.
CY20061101557T 2000-05-12 2006-10-30 Μεθοδος παρασκευης 2-χλωροτριφαινυλομεθυλοχλωριδιου συνδεδεμενου με πολυμερικη μητρα CY1105741T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00110039 2000-05-12
EP01956434A EP1280831B1 (de) 2000-05-12 2001-05-11 Verfahren zur herstellung von polymergebundenem 2-chlortritylchlorid
PCT/EP2001/005416 WO2001085758A2 (de) 2000-05-12 2001-05-11 Verfahren zur herstellung von polymergebundenem 2-chlortritylchlorid

Publications (1)

Publication Number Publication Date
CY1105741T1 true CY1105741T1 (el) 2010-12-22

Family

ID=8168685

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061101557T CY1105741T1 (el) 2000-05-12 2006-10-30 Μεθοδος παρασκευης 2-χλωροτριφαινυλομεθυλοχλωριδιου συνδεδεμενου με πολυμερικη μητρα

Country Status (10)

Country Link
US (1) US6828389B2 (el)
EP (1) EP1280831B1 (el)
AT (1) ATE335013T1 (el)
AU (1) AU2001278424A1 (el)
CY (1) CY1105741T1 (el)
DE (1) DE50110621D1 (el)
DK (1) DK1280831T3 (el)
ES (1) ES2269433T3 (el)
PT (1) PT1280831E (el)
WO (1) WO2001085758A2 (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100718431B1 (ko) * 2001-11-27 2007-05-14 주식회사 유앤비케미칼 트리틸기가 도입된 폴리스티렌 수지의 제조 방법
US20040209999A1 (en) * 2002-08-16 2004-10-21 Bohling James Charles Method of manufacturing polypeptides, including T-20 and T-1249, at commercial scale, and polypeptide compositions related thereto
US20040063856A1 (en) * 2002-09-30 2004-04-01 Bohling James Charles Resin for solid phase synthesis
DE60305976T2 (de) 2002-12-20 2006-11-16 F. Hoffmann-La Roche Ag Verfahren zur wiedergewinnung von festphasen harzgebundenem chlortritylchlorid
AU2004200485A1 (en) * 2003-02-25 2004-09-09 Rohm And Haas Company Method of manufacturing T-20 and T-1249 peptides at commercial scale, and T-20 and T-1249 compositions related thereto
CA3002871C (en) * 2015-10-23 2022-10-04 Cem Corporation Improvements in solid phase peptide synthesis
USRE49961E1 (en) 2016-10-21 2024-05-07 Cem Corporation Solid phase peptide syntheses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4346187A (en) * 1977-11-21 1982-08-24 Borg-Warner Chemicals, Inc. Flame retardant polypropylene compositions containing trityl synergists
JPS6254703A (ja) * 1985-09-04 1987-03-10 Kanegafuchi Chem Ind Co Ltd ルイス酸として作用する有機重合体
US5198531A (en) * 1991-06-14 1993-03-30 Research Diagnostic Antibodies Polymeric resin for peptide synthesis
JPH08217794A (ja) * 1995-02-15 1996-08-27 Bio Kosumosu:Kk 環状ペンタペプチド

Also Published As

Publication number Publication date
WO2001085758A2 (de) 2001-11-15
US6828389B2 (en) 2004-12-07
DE50110621D1 (de) 2006-09-14
ES2269433T3 (es) 2007-04-01
DK1280831T3 (da) 2006-11-27
EP1280831A2 (de) 2003-02-05
PT1280831E (pt) 2006-12-29
US20030092847A1 (en) 2003-05-15
AU2001278424A1 (en) 2001-11-20
WO2001085758A3 (de) 2002-01-31
EP1280831B1 (de) 2006-08-02
ATE335013T1 (de) 2006-08-15

Similar Documents

Publication Publication Date Title
CY1105741T1 (el) Μεθοδος παρασκευης 2-χλωροτριφαινυλομεθυλοχλωριδιου συνδεδεμενου με πολυμερικη μητρα
CY1114296T1 (el) Μεθοδος για την παρασκευη λειτουργικων πορωδων ινων
Wang et al. Visible-light-mediated defluorinative cross-coupling of gem-difluoroalkenes with thiols
ATE371702T1 (de) Verstärkte polymere
DE69811703D1 (de) Verfahren zur herstellung von konjugierten polymeren
ATE517857T1 (de) Herstellung von 4-phenylbutansäure
EP1158014A4 (en) METHOD FOR PRODUCING POLYMERS
Fritz et al. COFs meet graphene nanoribbons
Zhang et al. A traceless perfluorooctylsulfonyl tag for deoxygenation of phenols under microwave irradiation
DE60309060D1 (de) Verfahren zur alkylierung von salicylsäure
ATE276998T1 (de) Verfahren zur herstellung von (nitroxymethyl)phenylestern von salicylsäurederivaten
EP0834497A4 (en) PROCESS FOR PRODUCING 2- (HALOMETHYL) PHENYLACETIC ACID ESTERS
DE60020869D1 (de) Ein verfahren zur herstellung von hochreinem cefpodoxim-proxetil
ATE280198T1 (de) In-situ herstellung von bis- (benzothiazolesulfen)amid in polmerer matrix
ATE253030T1 (de) Verfahren zur herstellung von 1,1,4,4- tetramethoxybuten-2
Ito et al. Racemization and Deracemization of Poly (quinoxaline-2, 3-diyl) s.
KR20170078678A (ko) 뮤콘산 이성질체 및 그의 유도체로부터의 중합체
Cárdenas et al. Phenylenevinylene systems: The oligomer approach
DE50108686D1 (de) Verfahren zur herstellung von trifluorethoxysubstituierten benzoesäuren
Minta et al. Easy saponification by metal silanolates: application in SPPS and in (S)-5-hydroxynorvaline preparation
Yoshino et al. Facile preparation of polymer-supported methyl sulfonate and its recyclable use for methylation of carboxylic acids and amines
CN102367225B (zh) 一种萘普生的制备方法
CN114957614B (zh) 一种可见光促进的杂链高分子主链碳氢键胺基化的方法
ATE301637T1 (de) Verfahren zur herstellung von n-geschützten azetidin-2-carbonsäuren
Li et al. Asymmetric synthesis of free unusual β aminoacid esters via Yb (OTf) 3-caalyzed CC bond formation and simultaneous deprotection/purification