CU34329A - DERIVATIVES OF TIACINA - Google Patents

DERIVATIVES OF TIACINA

Info

Publication number
CU34329A
CU34329A CU34329A CU34329A CU34329A CU 34329 A CU34329 A CU 34329A CU 34329 A CU34329 A CU 34329A CU 34329 A CU34329 A CU 34329A CU 34329 A CU34329 A CU 34329A
Authority
CU
Cuba
Prior art keywords
lower alkyl
optionally substituted
same meaning
general formula
derivatives
Prior art date
Application number
CU34329A
Other languages
Spanish (es)
Inventor
Dieter Binder
Paul Zeller
Rudolf Pfister
Otto Hromatka
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CU34329A publication Critical patent/CU34329A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Procedimiento para la preparación de derivados de tiacina de la formula general: En la cual R1 significa alquilo inferior, R2 significa el radical de un heterociclo aromático con 1 a 3 heteroátomos, eventualmente substituidos por uno o dos grupos alquílicos inferiores o bien un radical fenílico, eventualmente sustituidos por halógeno, por alquilo inferior, por trifluorometilo o por alcoxilo inferior y R3 y R4 significan cada uno hidrógeno o alquilo inferior, caracterizado por hacerse reaccionar un compuesto de la formula II En la que R significa alquilo inferior, mientras que R1, R3 y R4 tienen el mismo significado que antes, con una amina de la formula general En la que R2 tiene el mismo significado que antes.Procedure for the preparation of thiazine derivatives of the general formula: In which R1 means lower alkyl, R2 means the radical of an aromatic heterocycle with 1 to 3 heteroatoms, optionally substituted by one or two lower alkyl groups or a phenyl radical, optionally substituted by halogen, by lower alkyl, by trifluoromethyl or by lower alkoxy and R3 and R4 each mean hydrogen or lower alkyl, characterized by reacting a compound of formula II In which R means lower alkyl, while R1, R3 and R4 have the same meaning as before, with an amine of the general formula Wherein R2 has the same meaning as before.

CU34329A 1974-08-26 1975-08-21 DERIVATIVES OF TIACINA CU34329A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1158274A CH608500A5 (en) 1974-08-26 1974-08-26 Process for the preparation of thiazine derivatives

Publications (1)

Publication Number Publication Date
CU34329A true CU34329A (en) 1980-10-30

Family

ID=4374870

Family Applications (1)

Application Number Title Priority Date Filing Date
CU34329A CU34329A (en) 1974-08-26 1975-08-21 DERIVATIVES OF TIACINA

Country Status (5)

Country Link
BE (1) BE832707A (en)
CH (1) CH608500A5 (en)
CU (1) CU34329A (en)
MX (1) MX160332A (en)
ZA (1) ZA755055B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69027594T2 (en) * 1989-11-30 1996-10-31 Nippon Hypox Lab Inc A MEDICINE CONTAINING THIAZINE DIOXIDE DERIVATIVE

Also Published As

Publication number Publication date
ZA755055B (en) 1976-07-28
CH608500A5 (en) 1979-01-15
BE832707A (en) 1976-02-25
MX160332A (en) 1993-08-01

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