CU20210092A7 - Péptidos bnip3 para el tratamiento de la lesión por reperfusión - Google Patents
Péptidos bnip3 para el tratamiento de la lesión por reperfusiónInfo
- Publication number
- CU20210092A7 CU20210092A7 CU2021000092A CU20210092A CU20210092A7 CU 20210092 A7 CU20210092 A7 CU 20210092A7 CU 2021000092 A CU2021000092 A CU 2021000092A CU 20210092 A CU20210092 A CU 20210092A CU 20210092 A7 CU20210092 A7 CU 20210092A7
- Authority
- CU
- Cuba
- Prior art keywords
- peptides
- bnip3
- treatment
- reperfusion injury
- bax
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7019—Ischaemia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7038—Hypoxia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
<p>La invención proporciona péptidos capaces de inhibir la actividad individual y la comunicación entre rutas de BNIP3, BAX y mitocondria. Los péptidos se pueden utilizar en métodos para tratar una enfermedad o condición en un sujeto en el que es deseable prevenir el daño celular y la muerte celular.</p>
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP19173715 | 2019-05-10 | ||
PCT/EP2020/062926 WO2020229362A1 (en) | 2019-05-10 | 2020-05-08 | Bnip3 peptides for treatment of reperfusion injury |
Publications (1)
Publication Number | Publication Date |
---|---|
CU20210092A7 true CU20210092A7 (es) | 2022-06-06 |
Family
ID=66483874
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CU2021000092A CU20210092A7 (es) | 2019-05-10 | 2020-05-08 | Péptidos bnip3 para el tratamiento de la lesión por reperfusión |
Country Status (15)
Country | Link |
---|---|
US (1) | US20220220174A1 (es) |
EP (1) | EP3966230A1 (es) |
JP (1) | JP2022532092A (es) |
KR (1) | KR20220007084A (es) |
CN (1) | CN114026114A (es) |
AU (1) | AU2020275076A1 (es) |
BR (1) | BR112021022156A2 (es) |
CA (1) | CA3138825A1 (es) |
CO (1) | CO2021015130A2 (es) |
CU (1) | CU20210092A7 (es) |
EA (1) | EA202192970A1 (es) |
IL (1) | IL287946A (es) |
MX (1) | MX2021013510A (es) |
SG (1) | SG11202112252UA (es) |
WO (1) | WO2020229362A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112608972B (zh) * | 2020-12-21 | 2021-09-10 | 广东源心再生医学有限公司 | Myog基因作为靶点在制备治疗心肌细胞凋亡相关的心血管疾病的药物中的应用 |
EP4333830A1 (en) * | 2021-05-04 | 2024-03-13 | Corvitus GmbH | Method for inhibiting reperfusion injury |
WO2023079141A2 (en) | 2021-11-05 | 2023-05-11 | Tienush Rassaf | Amelioration and treatment of infarction damage |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2838444B1 (fr) * | 2002-04-10 | 2016-01-01 | Neovacs | Nouveaux peptides et leur application en therapeutique |
AU2003256636A1 (en) * | 2002-07-22 | 2004-02-09 | University Of Miami | Preventing ischemia-induced cell damage |
EP2072527A1 (en) * | 2007-12-21 | 2009-06-24 | Altonabiotec AG | Fusion polypeptides comprising a SHBG dimerization component and uses thereof |
US20130196922A1 (en) * | 2010-07-21 | 2013-08-01 | University Of Manitoba | Bnip3 isoforms and methods of use |
-
2020
- 2020-05-08 US US17/608,655 patent/US20220220174A1/en active Pending
- 2020-05-08 EP EP20724123.3A patent/EP3966230A1/en active Pending
- 2020-05-08 BR BR112021022156A patent/BR112021022156A2/pt unknown
- 2020-05-08 EA EA202192970A patent/EA202192970A1/ru unknown
- 2020-05-08 WO PCT/EP2020/062926 patent/WO2020229362A1/en unknown
- 2020-05-08 MX MX2021013510A patent/MX2021013510A/es unknown
- 2020-05-08 CA CA3138825A patent/CA3138825A1/en active Pending
- 2020-05-08 CU CU2021000092A patent/CU20210092A7/es unknown
- 2020-05-08 CN CN202080044457.6A patent/CN114026114A/zh active Pending
- 2020-05-08 SG SG11202112252UA patent/SG11202112252UA/en unknown
- 2020-05-08 KR KR1020217039113A patent/KR20220007084A/ko unknown
- 2020-05-08 AU AU2020275076A patent/AU2020275076A1/en active Pending
- 2020-05-08 JP JP2021566026A patent/JP2022532092A/ja active Pending
-
2021
- 2021-11-09 CO CONC2021/0015130A patent/CO2021015130A2/es unknown
- 2021-11-09 IL IL287946A patent/IL287946A/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2020275076A1 (en) | 2021-11-25 |
MX2021013510A (es) | 2022-02-11 |
US20220220174A1 (en) | 2022-07-14 |
JP2022532092A (ja) | 2022-07-13 |
CA3138825A1 (en) | 2020-11-19 |
EA202192970A1 (ru) | 2022-03-03 |
SG11202112252UA (en) | 2021-12-30 |
CN114026114A (zh) | 2022-02-08 |
EP3966230A1 (en) | 2022-03-16 |
CO2021015130A2 (es) | 2021-11-30 |
KR20220007084A (ko) | 2022-01-18 |
WO2020229362A1 (en) | 2020-11-19 |
BR112021022156A2 (pt) | 2021-12-21 |
IL287946A (en) | 2022-01-01 |
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