CU20110130A7 - Uso de racematos de pinocembrin en la preparación de medicamentos para tratar isquemia - Google Patents
Uso de racematos de pinocembrin en la preparación de medicamentos para tratar isquemiaInfo
- Publication number
- CU20110130A7 CU20110130A7 CU20110130A CU20110130A CU20110130A7 CU 20110130 A7 CU20110130 A7 CU 20110130A7 CU 20110130 A CU20110130 A CU 20110130A CU 20110130 A CU20110130 A CU 20110130A CU 20110130 A7 CU20110130 A7 CU 20110130A7
- Authority
- CU
- Cuba
- Prior art keywords
- pinocembrin
- racemates
- medicines
- preparation
- treat ischemia
- Prior art date
Links
- URFCJEUYXNAHFI-ZDUSSCGKSA-N pinocembrin Chemical class C1([C@@H]2CC(=O)C3=C(O)C=C(C=C3O2)O)=CC=CC=C1 URFCJEUYXNAHFI-ZDUSSCGKSA-N 0.000 title abstract 6
- 239000003814 drug Substances 0.000 title abstract 3
- 208000028867 ischemia Diseases 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- RTIXKCRFFJGDFG-UHFFFAOYSA-N Chrysin Natural products C=1C(O)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=CC=C1 RTIXKCRFFJGDFG-UHFFFAOYSA-N 0.000 abstract 1
- 208000032382 Ischaemic stroke Diseases 0.000 abstract 1
- FGUBFGWYEYFGRK-HNNXBMFYSA-N Pinocembrin Natural products Cc1cc(C)c2C(=O)C[C@H](Oc2c1)c3ccccc3 FGUBFGWYEYFGRK-HNNXBMFYSA-N 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- KCFYHBSOLOXZIF-UHFFFAOYSA-N dihydrochrysin Natural products COC1=C(O)C(OC)=CC(C2OC3=CC(O)=CC(O)=C3C(=O)C2)=C1 KCFYHBSOLOXZIF-UHFFFAOYSA-N 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
Abstract
Uso de un racemato de pinocembrina, una sal de racenato de pinocembrina, un precursor del racemato de pinocembrina o un hidrato de racemato de pinocembrina en fabricación de un medicamento para profilaxis y tratamiento de la apoplejía. Particularmente, uso de racemato de pinocembrina en la fabricación de un medicamento para el tratamiento de la apoplejía isquémica aguda.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN200810185559 | 2008-12-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
CU20110130A7 true CU20110130A7 (es) | 2012-01-31 |
Family
ID=42242358
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CU20110130A CU20110130A7 (es) | 2008-12-11 | 2011-06-09 | Uso de racematos de pinocembrin en la preparación de medicamentos para tratar isquemia |
Country Status (17)
Country | Link |
---|---|
US (1) | US20110245334A1 (es) |
EP (1) | EP2377529A4 (es) |
JP (1) | JP5770098B2 (es) |
KR (1) | KR20110094136A (es) |
CN (1) | CN102548626A (es) |
AP (1) | AP2011005766A0 (es) |
AU (1) | AU2009326715B2 (es) |
BR (1) | BRPI0923242A8 (es) |
CA (1) | CA2746457A1 (es) |
CU (1) | CU20110130A7 (es) |
EA (1) | EA022275B1 (es) |
IL (1) | IL213440A0 (es) |
MX (1) | MX2011006141A (es) |
SG (1) | SG172072A1 (es) |
UA (1) | UA102874C2 (es) |
WO (1) | WO2010066199A1 (es) |
ZA (1) | ZA201105037B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10363288B2 (en) | 2015-01-14 | 2019-07-30 | National Jewish Health | Insulin mimotopes and methods of using the same |
AU2017236977B2 (en) | 2016-03-24 | 2022-05-26 | Immunomolecular Therapeutics, Inc. | Methods of treating autoimmune disease |
US11052060B2 (en) | 2018-02-12 | 2021-07-06 | The Regents Of The University Of Colorado, A Body Corporate | Compounds and methods for treating autoimmunity |
US11013707B2 (en) | 2018-03-23 | 2021-05-25 | The Regents Of The University Of Colorado, A Body Corporate | Administration of oral methyldopa |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5591771A (en) * | 1991-12-17 | 1997-01-07 | Michel Fockerman | Use of propolis components as an adjuvant |
UY26816A1 (es) * | 2001-07-04 | 2003-04-30 | Horacio Heinzen | Una preparación liposomal de achyrocline satureioides ("marcela"), flavonoides y derivados semisintéticos, para la protección del tejido cerebral frente al dano isquémico- vascular y neurodegenerativo. |
CN1285334C (zh) * | 2004-05-12 | 2006-11-22 | 中国医学科学院药物研究所 | 生松素在制备防治神经细胞损伤相关疾病药物中的应用 |
CN1879656B (zh) * | 2006-04-27 | 2010-04-21 | 魏春华 | 固体水溶性蜂胶组合物及其制备方法 |
CN101537188B (zh) * | 2007-03-21 | 2012-07-18 | 中国医学科学院药物研究所 | 松属素环糊精或环糊精衍生物包合物 |
CN101307044B (zh) * | 2007-05-16 | 2012-07-04 | 中国医学科学院药物研究所 | 生松素化合物两种晶型和制备方法及在疾病治疗中的应用 |
US20090232782A1 (en) * | 2008-03-14 | 2009-09-17 | Yu-Show Fu | Method for treating brain ischemic injury through transplantation of human umbilical mesenchymal stem cells |
AP2011005707A0 (en) * | 2008-11-11 | 2011-06-30 | Cspc Zhongqi Pharmaceutical Technology Shijiazhuang Co Ltd | Inclusion complexes of pinocembrin with cyclodextrin or its derivatives. |
-
2009
- 2009-12-10 AP AP2011005766A patent/AP2011005766A0/xx unknown
- 2009-12-10 US US13/133,894 patent/US20110245334A1/en not_active Abandoned
- 2009-12-10 EA EA201170776A patent/EA022275B1/ru not_active IP Right Cessation
- 2009-12-10 WO PCT/CN2009/075456 patent/WO2010066199A1/zh active Application Filing
- 2009-12-10 MX MX2011006141A patent/MX2011006141A/es not_active Application Discontinuation
- 2009-12-10 CA CA2746457A patent/CA2746457A1/en not_active Abandoned
- 2009-12-10 SG SG2011042363A patent/SG172072A1/en unknown
- 2009-12-10 AU AU2009326715A patent/AU2009326715B2/en not_active Ceased
- 2009-12-10 CN CN2009801537942A patent/CN102548626A/zh active Pending
- 2009-12-10 BR BRPI0923242A patent/BRPI0923242A8/pt not_active IP Right Cessation
- 2009-12-10 UA UAA201108565A patent/UA102874C2/uk unknown
- 2009-12-10 KR KR1020117015995A patent/KR20110094136A/ko not_active Application Discontinuation
- 2009-12-10 JP JP2011539884A patent/JP5770098B2/ja not_active Expired - Fee Related
- 2009-12-10 EP EP09831476.8A patent/EP2377529A4/en not_active Withdrawn
-
2011
- 2011-06-09 CU CU20110130A patent/CU20110130A7/es unknown
- 2011-06-09 IL IL213440A patent/IL213440A0/en unknown
- 2011-07-08 ZA ZA2011/05037A patent/ZA201105037B/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP2377529A1 (en) | 2011-10-19 |
WO2010066199A1 (zh) | 2010-06-17 |
EA201170776A1 (ru) | 2011-12-30 |
EA022275B1 (ru) | 2015-12-30 |
UA102874C2 (uk) | 2013-08-27 |
AU2009326715B2 (en) | 2015-12-03 |
CA2746457A1 (en) | 2010-06-17 |
US20110245334A1 (en) | 2011-10-06 |
EP2377529A4 (en) | 2013-05-22 |
KR20110094136A (ko) | 2011-08-19 |
JP2012511518A (ja) | 2012-05-24 |
BRPI0923242A2 (pt) | 2016-01-26 |
SG172072A1 (en) | 2011-07-28 |
AP2011005766A0 (en) | 2011-06-30 |
BRPI0923242A8 (pt) | 2016-09-13 |
JP5770098B2 (ja) | 2015-08-26 |
AU2009326715A1 (en) | 2011-07-14 |
MX2011006141A (es) | 2011-09-21 |
ZA201105037B (en) | 2012-09-26 |
IL213440A0 (en) | 2011-07-31 |
CN102548626A (zh) | 2012-07-04 |
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