CS641988A2 - Method of 1,4-dihydropyridines production - Google Patents
Method of 1,4-dihydropyridines productionInfo
- Publication number
- CS641988A2 CS641988A2 CS886419A CS641988A CS641988A2 CS 641988 A2 CS641988 A2 CS 641988A2 CS 886419 A CS886419 A CS 886419A CS 641988 A CS641988 A CS 641988A CS 641988 A2 CS641988 A2 CS 641988A2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- alkyl
- opt
- ring
- substd
- piperazinyl
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
4-Aryl-5-carbamoyl-1,4-dihydropyridine cpds. of formula (I) and their salts are new. (R = phenyl opt. substd. or is phenyl fused to a dioxolane ring; R1, R2 = H or 1-6C alkyl, or R1 and R2 together complete a pyrrolidinyl, piperidono, morpholino, piperazinyl, N-(1-4C alkyl)piperazinyl or N-(2-4C alkanoyl)piperazinyl gp.; or R2 is H or 1-4C alkyl and R1 is CN, 3-7C cycloalkyl, aryl, heteroaryl or a 1-4C alkyl gp., the 1-4C alkyl gp. of R1 being substd.; Z = 1-6C alkoxy, aryl(1-4C)alkoxy OH or NR4R5; R4, R5 = H or 1-6C alkyl or R4 and R5 together complete a pyrrolidine, piperidino, morpholino, piperazinyl or N-(1-4C alkyl)piperazinyl gp.; Y = 1,4-phenylene or pyridine-2,5-diyl; X = a 5 or 6 membered aromatic heterocyclic gp. contg. N atom(s) in its ring, which ring may be fused to a benzene ring or to a further 5- or 6-membered aromatic heterocyclic ring contg. N atom(s), heterocyclic ring(s) opt. also contg. an O or S atom and being opt. substd.; aryl = phenyl opt. substd., heteroaryl in the definition of R1 = 5- or 6-membered aromatic heterocyclic gp. contg. heteroatom(s) selected from N, O and S and which may opt. be fused to a benzene ring and which may opt. be substd. in heterocyclic and fused benzene ring(s).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CS886419A CS270592B2 (en) | 1988-09-28 | 1988-09-28 | Method of 1,4-dihydropyridines production |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CS886419A CS270592B2 (en) | 1988-09-28 | 1988-09-28 | Method of 1,4-dihydropyridines production |
Publications (2)
Publication Number | Publication Date |
---|---|
CS641988A2 true CS641988A2 (en) | 1989-11-14 |
CS270592B2 CS270592B2 (en) | 1990-07-12 |
Family
ID=5411180
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS886419A CS270592B2 (en) | 1988-09-28 | 1988-09-28 | Method of 1,4-dihydropyridines production |
Country Status (1)
Country | Link |
---|---|
CS (1) | CS270592B2 (en) |
-
1988
- 1988-09-28 CS CS886419A patent/CS270592B2/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CS270592B2 (en) | 1990-07-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MY104933A (en) | Platelet activating factor antagonists | |
DE3578605D1 (en) | CEPHALOSPORINE DERIVATIVES. | |
CS641988A2 (en) | Method of 1,4-dihydropyridines production | |
ES8601151A1 (en) | Substituted phenylsulfonylguanidine derivatives. | |
NO951081L (en) | Aminoalkylbenzoxazolinones and benzothiazolinones | |
KR900007371B1 (en) | Storage stable aryl-nitrone composition and method thereof | |
FR2376137A1 (en) | 5-Cyano-1,4-di:hydro-pyridine-3-carboxylate ester(s) - useful as coronary dilators | |
HUT43078A (en) | Process for producing cepheme compounds | |
FR2429213A1 (en) | Benzylamine derivs. with bromo and methoxy substits. on benzene ring - useful in prepn. of antispasmodic norbornane derivs. | |
ES8604505A1 (en) | 1-(4'Alkylsulfonylphenyl)-2-amino-1,3-propanediol N-substituted derivatives. | |
EP0233291A4 (en) | 2-arylbenzothiazine derivatives. | |
GB2093031B (en) | 4-aroylimidazol-2-ones | |
ES431804A1 (en) | Acylated 2-aminothiazole derivatives | |
DE3867563D1 (en) | 2-amino-5-hydroxy-4-pyrimidone. | |
IE781449L (en) | Imidazo-isoquinoline-diones | |
ES8504156A1 (en) | 5-Aminoisoxazole derivatives | |
ES8403853A1 (en) | Aminoalkyl naphthalene derivatives, their salts, process for their preparation and the therapeutical use of these derivatives and salts. | |
FR2166101A1 (en) | 1,4-di (morpholino,piperidino or pyrrolidino)-7-substd - -pyrido (3,4-d)-pyridazines - as diuretics | |
IT1230754B (en) | New 1-heterocyclyl-2-amino-ethanol cpds. | |
IT1201455B (en) | New 2-aminoalkyl-4 phenyl-di:hydro-pyridine di:carboxylate derivs. | |
IT1217657B (en) | New 1-heterocyclyl-2-amino-ethanol cpds. | |
PT73274A (en) | Process for preparing new naphthimidazole and naphthoxazole derivatives and pharmaceutical compositions containing the same | |
IT1204458B (en) | New 2-aminoalkyl-4 phenyl-di:hydro-pyridine di:carboxylate derivs. | |
SE8503088D0 (en) | NEW PARA-SUBSTITUTED 3-PHENOXY-1-PIPERIDINECARBONYL-AMINOALKYLAMINO-PROPANOL-2-S HAVING BETA RECEPTOR BLOCKING PROPERTIES |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
IF00 | In force as of 2000-06-30 in czech republic | ||
MM4A | Patent lapsed due to non-payment of fee |
Effective date: 20050928 |