CS391391A3 - Benzopyran isomers, process of their preparation and pharmaceuticalscomprising thereof - Google Patents

Benzopyran isomers, process of their preparation and pharmaceuticalscomprising thereof Download PDF

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Publication number
CS391391A3
CS391391A3 CS913913A CS391391A CS391391A3 CS 391391 A3 CS391391 A3 CS 391391A3 CS 913913 A CS913913 A CS 913913A CS 391391 A CS391391 A CS 391391A CS 391391 A3 CS391391 A3 CS 391391A3
Authority
CS
Czechoslovakia
Prior art keywords
isomer
compound
formula
weight
optionally
Prior art date
Application number
CS913913A
Other languages
Czech (cs)
English (en)
Inventor
Erol Faruk
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of CS391391A3 publication Critical patent/CS391391A3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CS913913A 1983-03-24 1991-12-19 Benzopyran isomers, process of their preparation and pharmaceuticalscomprising thereof CS391391A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838308062A GB8308062D0 (en) 1983-03-24 1983-03-24 Active compounds

Publications (1)

Publication Number Publication Date
CS391391A3 true CS391391A3 (en) 1992-09-16

Family

ID=10540102

Family Applications (1)

Application Number Title Priority Date Filing Date
CS913913A CS391391A3 (en) 1983-03-24 1991-12-19 Benzopyran isomers, process of their preparation and pharmaceuticalscomprising thereof

Country Status (12)

Country Link
EP (1) EP0120428B1 (fr)
JP (1) JPH0791188B2 (fr)
AU (1) AU571498B2 (fr)
CA (1) CA1284150C (fr)
CS (1) CS391391A3 (fr)
DE (1) DE3482323D1 (fr)
ES (1) ES8607964A1 (fr)
GB (1) GB8308062D0 (fr)
GR (1) GR81923B (fr)
IE (1) IE57119B1 (fr)
NZ (1) NZ207594A (fr)
ZA (1) ZA842123B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT84806B (pt) * 1986-05-03 1989-12-29 Beecham Group Plc Processo para a preparacao de benzopiranos
GB8625185D0 (en) * 1986-10-21 1986-11-26 Beecham Group Plc Active compounds
DE3703227A1 (de) * 1987-02-04 1988-08-18 Hoechst Ag Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
DE3881714D1 (de) * 1987-02-04 1993-07-22 Hoechst Ag Alkylsubstituierte n-benzopyranyllactame, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen.
CH674984A5 (fr) * 1987-05-16 1990-08-15 Sandoz Ag
DE3811017A1 (de) * 1988-03-31 1989-10-19 Hoechst Ag Ungesaettigte n-benzopyranyllactame
DE3818245A1 (de) * 1988-05-28 1989-12-07 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit kaliumkanal-modulatoren sowie deren verwendung in arzneimitteln
US4988723A (en) * 1988-06-02 1991-01-29 Fujisawa Pharmaceutical Co., Ltd. Benzopyran derivatives and their use as anti-hypertensives
DE3823533A1 (de) * 1988-07-12 1990-02-08 Beiersdorf Ag Substituierte 4-heterocyclyl-2h-benzo(b)pyrane, verfahren und 4-hydroxy-3-brom-, 3,4-oxiranyl-3,4-dehydro-2h-benzo(b)pyrane als zwischenprodukte zu ihrer herstellung, sowie sie enthaltende pharmazeutsche praeparate
DE3901720A1 (de) * 1989-01-21 1990-07-26 Hoechst Ag Substituierte benzo(b)pyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
GB8902118D0 (en) * 1989-02-01 1989-03-22 Beecham Group Plc Chemical process
US5239090A (en) * 1989-02-01 1993-08-24 Beecham Group P.L.C. Certain optically active 3,4-dihydrobenzopyran-4-ols which are intermediates
US5066816A (en) * 1989-03-03 1991-11-19 Yoshitomi Pharmaceutical Industries, Ltd. Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2h-1-benzopyran compounds and intermediates therefor
US5162553A (en) * 1989-03-03 1992-11-10 Yoshitomi Pharmaceutical Industries, Ltd. Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds and intermediates therefor
IE63935B1 (en) * 1989-06-27 1995-06-28 Chem Pharm Forsch Gmbh Novel thienopyran derivatives a process for their preparation and their use
DE3922392A1 (de) 1989-07-07 1991-01-17 Merck Patent Gmbh Chromanderivate
HU207861B (en) * 1989-07-21 1993-06-28 Alkaloida Vegyeszeti Gyar Process for producing benzopirane derivative of blood pressure lowering activity
HUT72741A (en) * 1992-12-19 1996-05-28 Alkaloida Vegyeszeti Gyar Method for producing benzopyrane derivatives and pharmaceutical compositions containing them
US6417207B1 (en) 1999-05-12 2002-07-09 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
WO2015117024A1 (fr) 2014-01-31 2015-08-06 Mayo Foundation For Medical Education And Research Nouveaux agents thérapeutiques pour le traitement du glaucome

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1548222A (en) * 1976-12-17 1979-07-04 Beecham Group Ltd Trans-4-heterocyclyl-3,4-dihydro-2h-benzo pyarn-3-ol derivatives
EP0009912B1 (fr) * 1978-10-04 1983-06-22 Beecham Group Plc Dérivés de chromanol, procédé pour leur préparation et compositions pharmaceutiques les contenant
GB2064514B (en) * 1979-10-29 1984-01-18 Maruko Pharmaceutical Co Flavan compounds and acid addition salts thereof and pharmaceutical compositions thereof
EP0033612B1 (fr) * 1980-02-02 1984-04-11 Beecham Group Plc Dérivés pyraniques, procédé pour leur préparation et compositions antihypertensives les contenant
GB2107706A (en) * 1981-09-25 1983-05-05 Beecham Group Plc Benzopyrans
JPH0471072A (ja) * 1990-07-11 1992-03-05 Fujitsu Ltd アナログ／ディジタル混載集積回路のシミュレーション方法

Also Published As

Publication number Publication date
GB8308062D0 (en) 1983-05-05
GR81923B (fr) 1984-12-12
JPH0791188B2 (ja) 1995-10-04
AU571498B2 (en) 1988-04-21
IE840707L (en) 1984-09-24
IE57119B1 (en) 1992-05-06
ZA842123B (en) 1985-04-24
JPS59176282A (ja) 1984-10-05
NZ207594A (en) 1987-07-31
ES8607964A1 (es) 1986-06-01
EP0120428A1 (fr) 1984-10-03
EP0120428B1 (fr) 1990-05-23
ES530958A0 (es) 1986-06-01
CA1284150C (fr) 1991-05-14
DE3482323D1 (de) 1990-06-28
AU2600784A (en) 1984-09-27

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