CS267944B1 - Method of ethylene-oxide indicator papers preparation - Google Patents

Abstract

To prepare a detection paper for ethylene oxide, characterized by β solution containing 0.2 to 0.5 wt. cobalt (II) chloride diols, 0.1 to 0.7% by weight, parts of potassium hydrogen sulphate, 0.005 to 0.1% by weight, parts of brm-phenol blue, and 98.7 to 99.7% by weight of alcohol, are impregnated with filtered paper for 5 to 10 minutes, and then dried at 50 to 70 ° C in a conventional temperature apparatus.

Description

The invention relates to a process for the preparation of detection papers for detecting the presence of ethylene oxide.

At present, ethylene oxide has a wide range of uses in the sterilization of medical materials, the preservation of documents in archives, etc. Monitorovanle processor sterilization · It is based on the use of materials impregnated with a reagent that is colored by the action of ethylene oxide. A wide variety of organic azo dyes are currently used for this purpose (Japan Kokai Tokkyo Koho, JP 60,248,782, JP 6,015,330, JP 59,219,375, JP 5,936,172, JP 8,069,671, US 4,015 937). Azo dyes are in the form of inks, foils, packaging, etc. Methyl methacrylates or methyl methacrylate copolymers (JP 60,248,782), phenolic resins and ethylcellulose (JP 6,015,330), modified malelic acid resin (JP 5,936,172), polyamide (US 4,4θ7,96θ), nitrool 78,138,393), polyethylene glycol (US 3,992,154).

The species group of roagents consists of inorganic salts. Chromenes and dichromates are used applied on a polyester film (JP 7,449,693) in the composition! with iodine oxide, the color of ethylene oxide turns blue. Also used are compounds which react to form a basic product and change the carbonyl to change the pH of the sensitive dye. This includes a monitoring system composed of anhydrous magnesium chloride, sodium bisulfate and bromophenol blue (US 4,138,216).

In contrast to these known methods, a process for the preparation of detection papers for ethylene oxide has been verified, in which a solution containing 0.2 to 0.5 parts by weight of cobalt trichloride, 0.1 to 0.7 parts by weight, parts of potassium bisulfate, 0.005 to 0%, 01 parts by weight of bromophenol blue and 98.7 to 99.7 parts by weight of alcohol are impregnated on the filter paper for 5 to 10 minutes and then dried at 50 to 70 DEG C. in conventional type temperature equipment.

The advantage of this procedure over the above is that both the ethylene oxide sensitive reagent and the impregnated material are commonly available, the preparation of detection papermaking is very simple and the ethylene oxide moiety is very sensitive.

Specific methods of carrying out the subject matter of the invention are given in the following examples.

Example 1

0.2 g of cobalt trichloride, 0.1 potassium bisulfate and 0.008 g of bromophenol blue are dissolved in 100 g of denatured ethyl alcohol. The mixture is then impregnated with filter paper for 10 minutes. At the end of the impregnation, the paper is left to dry in an oven at 60 ° C. The paper thus prepared is colored blue with the action of ethylene oxide over a period of 5 minutes. Sfarbenle is still at least 24 hours.

Example 2 0.5 g of cobalt trichloride, 0.5 g of potassium bisulfate and 0.012 g of bromophenolose are dissolved in a methanol / ethyl alcohol mixture in a ratio of 7/3 by volume. The procedure is as described in Example 1.

Claims (1)

OBJECT OF THE INVENTION The process for the preparation of ethylene oxide detection papers is characterized in that the β-rocking system contains 0.2 to 0.5 parts by weight, parts of cobalt trichloride, 0.1 to 0.7 parts by weight, parts of potassium hydrogen sulphate, 0.005 to 0.01 parts by weight. bromophenol blue and 98.7 to 99.7 parts by weight of alcohol, and impregnates the filtered paper for 5 to 10 minutes and not. and dried in January at a temperature of 5θ to 70 ° C in temperature devices.