CS266429B1 - Disinfectant - Google Patents

Abstract

The invention relates to a disinfectant additive intended especially for detergents and raw materials for their production, the essence of which is that it contains a mixture of monoterpene alcohols from coniferous trees and dihydric alcohol. The disinfectant additive prevents the growth of microflora β microfauna in detergents and raw materials intended for their production.

Description

The invention relates to a disinfectant additive composed of monoterpene alcohols from conifers and dihydric alcohols, which is intended in particular for detergents and raw materials for their production.

Liquid and pasty detergents, despite all the attention paid to the cleanliness of the hygiene of the production environment, contain a number of microbial germs, some of which can be pathogenic. For ecological reasons, biodegradable surfactants are used for the production of the above-mentioned compositions, which are in fact a suitable breeding ground for the growth of microorganisms. It happens because these media multiply by multiplying the microflora and microfauna, and these products become goat during the harvest period and are unusable before the end of the warranty period. In addition, pasty detergents, especially hand cleansing pastes, contain an abrasive component which abrades the skin during washing, so that harmful microorganisms may be incorporated at the points of its weakening or damage, which in turn leads to various local inflammations or chronic biosterio or mycosis. These problems are currently commonly addressed by the addition of various traditional preservative additives such as 2,2-dihydroxy-3,5,6,3,5,6-hexashloriphenylmethane / hexachlorophene / various brominated salicylanilides, chlorobenzylphenols, 2-methylthiophenyl- 5β-iodopropargyloxy / pyrimidine (Daritin), various quaternary ammonium compounds and many other compounds.

The disinfectant must meet a number of requirements, the basic condition being that it must not react with the other ingredients contained in the detergent. Due to the

266,429 to the fact that these compositions contain a number of compounds and different functional groups, the limited choice of these additives is narrowed down. Another limiting condition for the use of these disinfectant additives is their non-toxicity, dermal tolerability, i.e. non-irritancy, and even with prolonged use, the skin must not be hypersensitive or even allergic. Furthermore, the disinfectant must be well dispersible, which is problematic especially for non-polar compounds, since detergents are solutions or suspensions of polar substances in water. Last but not least, due to the volume and relatively low price of the mentioned means, there is also an economic factor, ie the price of the disinfectant additive. Finally, the disinfectant must be effective for a wide range of microorganisms, i.e., it must have both antibacterial and antifungal effects.

The use of the above-mentioned halogen derivatives and other synthetic substances thus prevents the growth of microorganisms in detergents, but at the same time their use causes the skin and thus the human body to come into contact with other chemical compounds. have passed all the prescribed tests, the test period (months) is short compared to the fact that hand cleansing pastes have been used in some professions for decades, in fact for the entire period of employment. Although synthetic disinfectants vary, they are usually based on analogous compounds, and then allergies can occur during long-term use, which are then difficult to cause. In addition, in contact with the skin, these disinfectants, due to their high lipophilicity, adhere to the skin and penetrate the human body during the course of the period, in which undesired residues accumulate.

Based on the above facts, it can therefore be seen that the requirement for a composition free of microorganisms and at the same time absolutely free of all undesirable substances is contradictory.

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- 3 In contrast, there is a number of professional and scientific works on the antiaicrobial effects of various natural essential oils. However, 3e many! difficult to obtain specific data applicable in practice on the basis of this published information. Due to the fact that the spectra of selected substances and the selection of tested organisms are very different, on the other hand, the tested methods are so different that it is not possible to make at least an indicative selection on the basis of these data. Because natural essential oils are almost insoluble in water, they cannot be applied in their original form. In order to use them, it is first necessary to convert them into such an application form which would guarantee their perfect halogenation in the detergent.

The above-mentioned disadvantages do not have a disinfectant additive, intended mainly for detergents and raw materials for their production, the essence of which is that it contains a mixture of monoterpene alcohols from coniferous trees and dihydric alcohol with 2 to 6 carbon atoms in a weight ratio of 1: 1 to 100.

The advantage of the disinfectant additive according to the invention is that it contains natural substances with biocidal effects which do not have a detrimental effect on the human body and which are compatible with human skin. With these substances, plants defend against infestation by bacteria and fungi (molds). The results in the specific compositions have shown that the minimum inhibitory concentrations for Candida albicans, Staphylococus aureus, Eecherichis coll, Pssudoaonas aeuroginosa and Aspergillus niger are in the range of 20 to 60 ppm in a real detergent. Thus, a dosage of 100 ppm (tJ, 0.01%) reliably guarantees the cessation of the growth of microbial cultures, and at a dosage in the region of 200 ppm (i.e. 0.02%) a biocidal effect can already be detected. At the same time, this effect is achieved at post-fire concentrations, and it is a mixture of substances that are of natural origin and are well tolerated by the skin. Another advantage is the fact that it is possible to apply sparingly soluble essential oils to liquid and pasty detergents and cleaners, to find their combination with suitable solvents so that their biocidal activity is as high as possible.

Sashes of monoterpene alcohols obtained from conifers (eg Pícea excelsa L., Pinus silvesstris L., Abies alba, etc.) contain · geraniol, terpineol, nerol, nerolidol, linalool, citral aldehyde and many other minor components. It is difficult to determine which of these compounds is the carrier of the biostatic and biocidal effect, since all compounds in isolation have this effect lower in some cases up to an order of magnitude, so it is an eynergic mixture.

The invention is further illustrated by the following examples, which do not limit the scope of the invention in any way.

Examples Example 1

To prepare the hand washing paste, 26 kg of wood flour, 21 kg of water, 10 kg of sulphated adduct of leuryl alcohol with ethylene oxide (30%), 8 kg of greasy soap, 3 kg of bentonite, 30 kg of kaolin and 2 kg of a solution formed by dissolving 1% are thoroughly mixed. g of monothermic alcohols obtained from Norway spruce in 1900 g of propylene glycol. Ten samples of the hand paste thus prepared were contaminated with the mixture of microorganisms mentioned above in the description of the invention, and in no case was the growth of microorganisms observed in the microbiological analysis (monitoring period 24 weeks, temperature 28 ° C). In contrast, out of 10 contaminated control samples without the addition of a mixture of monoterpene alcohols, only 1 was recorded in which no microorganisms grew, in the other 9 a sharp growth of microorganisms was recorded after 1 week and after 4 weeks these samples were commercially unusable.

Example 2

To prepare the washing liquid suspension, 55.1 kg of water, 11.5 kg of sodium dodecylbenzenesulfonate, 6.4 kg of sodium soap, 22.4 kg of sodium tripolyphosphate, 2.6 kg of diethanolamide are thoroughly mixed successively.

266 429 oleic acid, 1.0 kg of coconut acid monoethanolamide and 1.0 kg of solution formed by dissolving 50 g of monoterpene alcohols obtained from white fir in 800 g of propylene glycol and 150 g of diethylene glycol. Under none of the 10 samples with the content of monoterpene alcohols the growth of microorganisms was recorded, in contrast in 8 out of 10 control samples without disinfectant the growth of microorganisms was recorded already after 1 week.

Example 3

To prepare a liquid hand detergent, 49 kg of water, 26 kg of wood flour, 10 kg of sulfosuccinate based on coconut acid monoethanolamide (40%), 8 kg of potassium soap, 3 kg of bentonite, 4 kg of solution formed by dissolving 200 g of monoterpene alcohols are thoroughly mixed. in 3,800 g of propylene glycol. Under the conditions described in Example 1, no growth of microorganisms was observed in any of the 10 samples containing monoterpene alcohols, in contrast, in 10 of the 10 control samples without disinfectant, the growth of microorganisms was already recorded after 1 week.

Example 4

To prepare the pasty detergent, 32 kg of water, 15 kg of sodium dodecylbenzenesulfonate, 9 kg of sodium soap, 34 kg of sodium tripolyphosphate, 3 kg of oleic acid diethanolamide, 2 kg of coconut monoethanolamide and 5 kg of solution formed by dissolving 250 g of monoterpene alcohols in 4,750 g of propylene glycol. Under the conditions described in Example 1, no growth of microorganisms was observed in any of the 10 samples containing monoterpene alcohols, in contrast, in 7 of the 10 control samples without disinfectant, the growth of microorganisms was already recorded after 1 week.

- 6 Example 5

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350 l of water are poured into a stirred duplicated reactor, heated to 40 DEG C. and 155 kg of dodecylbenzenesulfonic acid and 39.6 kg of 3.8% ammonia are added, followed by 134 kg of 38% sodium lauryl sulfate, 206 kg of 29% lauryl triethylene glycol sulfate. sodium, 31 kg of diethanolamide oleic acid, 103 kg of oleylaminoethyltotraethylene glycol and 96% finally add a solution of 400 g of monoterpene alcohols obtained from steppe spruce in 1000 g of propylene glycol. Ten samples of the dishwashing detergent thus prepared were contaminated with the microorganisms mentioned In contrast, in one case, microbiological analysis did not indicate the growth of microorganisms. In contrast, of the 10 combined control samples without the addition of monoterpene alcohols, only 2 were recorded in which no microorganisms grew;

Example 6

602 kg of water are charged to the stirred duplicate reactor, 8 kg of sodium hydroxide, 70 kg of dodecylbenzenesulfonic acid are added and the mixture is allowed to stir. After 10 minutes, 10 kg of lauryloctahothylonglycol, 150 kg of monoethanolane ammonium nitriloacetate, 20 kg of a mixture of diathanolamine and triethanolamine are added and stirred for 10 minutes. Then 40 kg of a 30% aqueous solution of the sodium oleate of nitrilotriacetic acid are added, followed by 30 kg of powdered soap, 20 kg of sodium pyrophosphate and 50 kg of sodium cumene sulphonate and 6 kg of a solution of 400 g of monoterpene alcohols obtained from Scots pine in 5400 g of propylene glycol. In Example 1, no growth of microorganisms was observed in any of the 10 samples of liquid detergent containing monoterpene alcohols.

- 7 Example 7 266 429

860 kg of water are introduced into a stirred duplicated reactor, the mixture is heated to 50 DEG C., 120 kg of N, N-diethyl-N-methyl-NZ-staaroyloxyethylammonium methyl sulfate and 20 kg of myrystyloctedecylene glycol are added and the mixture is stirred for 1 hour, then 2000 g of solution are added. 200 g of monoterpene alcohols obtained from ethyl spruce in 1800 g of propylene glycol. Under the conditions described in Example 1, no growth of microorganisms was observed in one of the 10 samples of the weighing agent containing monotherpenic alcohols, and in contrast, in 7 of the 10 control samples without disinfectant no growth of microorganisms was recorded after 1 week.

Example 8

A solution of 200 g of a mixture of monoterpene pine alcohols in 2000 g of propylene glycol is added at 1000 DEG C. to 1000 g of 40% dinetrium 2-oleyl amino monoulfoeuccinate at 70 DEG C. Under the conditions described in Example 1, the growth of microorganisms was not detected in one of the 10 samples of eulfoeuccinate, whereas in 6 of the 10 samples without disinfectant the growth of microorganisms was detected after only 2 weeks.

Claims (1)

Disinfectant is intended mainly for detergents with raw materials for their production, characterized by circulating a mixture of monotherpenic alcohols from coniferous woods and dihydric alcohols with the number of carbon etomes 2 to 6 in a weight ratio of 1: 1 to 100.