CS258001B1 - Method of ergotamine production - Google Patents
Method of ergotamine production Download PDFInfo
- Publication number
- CS258001B1 CS258001B1 CS794080A CS794080A CS258001B1 CS 258001 B1 CS258001 B1 CS 258001B1 CS 794080 A CS794080 A CS 794080A CS 794080 A CS794080 A CS 794080A CS 258001 B1 CS258001 B1 CS 258001B1
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- ergotamine
- tul
- production
- ibp
- lav lav
- Prior art date
Links
- OFKDAAIKGIBASY-VFGNJEKYSA-N ergotamine Chemical compound C([C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@@](C(N21)=O)(C)NC(=O)[C@H]1CN([C@H]2C(C3=CC=CC4=NC=C([C]34)C2)=C1)C)C1=CC=CC=C1 OFKDAAIKGIBASY-VFGNJEKYSA-N 0.000 title claims 4
- 229960004943 ergotamine Drugs 0.000 title claims 4
- XCGSFFUVFURLIX-UHFFFAOYSA-N ergotaminine Natural products C1=C(C=2C=CC=C3NC=C(C=23)C2)C2N(C)CC1C(=O)NC(C(N12)=O)(C)OC1(O)C1CCCN1C(=O)C2CC1=CC=CC=C1 XCGSFFUVFURLIX-UHFFFAOYSA-N 0.000 title claims 4
- 238000004519 manufacturing process Methods 0.000 title claims 2
- 238000000034 method Methods 0.000 title claims 2
- HEEACTTWORLLPM-UHFFFAOYSA-N 2-(1h-imidazol-5-yl)ethanol Chemical compound OCCC1=CNC=N1 HEEACTTWORLLPM-UHFFFAOYSA-N 0.000 claims description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical class N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical class [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 238000010564 aerobic fermentation Methods 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 229910052500 inorganic mineral Chemical class 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 239000011707 mineral Chemical class 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 241000221751 Claviceps purpurea Species 0.000 description 5
- 241000221760 Claviceps Species 0.000 description 2
- XGZRAKBCYZIBKP-UHFFFAOYSA-L disodium;dihydroxide Chemical compound [OH-].[OH-].[Na+].[Na+] XGZRAKBCYZIBKP-UHFFFAOYSA-L 0.000 description 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Inorganic materials [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 2
- WUBBRNOQWQTFEX-UHFFFAOYSA-N 4-aminosalicylic acid Chemical compound NC1=CC=C(C(O)=O)C(O)=C1 WUBBRNOQWQTFEX-UHFFFAOYSA-N 0.000 description 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 241000368779 Asota Species 0.000 description 1
- 101100120289 Drosophila melanogaster Flo1 gene Proteins 0.000 description 1
- 229910005390 FeSO4-7H2O Inorganic materials 0.000 description 1
- 229910005444 FeSO4—7H2O Inorganic materials 0.000 description 1
- 101150096418 Mepe gene Proteins 0.000 description 1
- 206010037549 Purpura Diseases 0.000 description 1
- 241001672981 Purpura Species 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- CSNNHWWHGAXBCP-UHFFFAOYSA-L magnesium sulphate Substances [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
Landscapes
- Crystals, And After-Treatments Of Crystals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DD21723579A DD234172A3 (de) | 1979-07-16 | 1979-07-16 | Verfahren zur herstellung von ergotamin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS258001B1 true CS258001B1 (en) | 1988-07-15 |
Family
ID=5521316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS794080A CS258001B1 (en) | 1979-07-16 | 1980-11-20 | Method of ergotamine production |
Country Status (2)
| Country | Link |
|---|---|
| CS (1) | CS258001B1 (de) |
| DD (1) | DD234172A3 (de) |
-
1979
- 1979-07-16 DD DD21723579A patent/DD234172A3/de unknown
-
1980
- 1980-11-20 CS CS794080A patent/CS258001B1/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DD234172A3 (de) | 1986-03-26 |
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