CS239181B1 - An agent for the treatment of tonsillitis and larynx - Google Patents
An agent for the treatment of tonsillitis and larynx Download PDFInfo
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- CS239181B1 CS239181B1 CS8310299A CS1029983A CS239181B1 CS 239181 B1 CS239181 B1 CS 239181B1 CS 8310299 A CS8310299 A CS 8310299A CS 1029983 A CS1029983 A CS 1029983A CS 239181 B1 CS239181 B1 CS 239181B1
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Abstract
Očelnm vynálezu je příprava prostriedku, ktorý sa používá na liečenie zápalov mandlí a hrtana. Nový prostriedok sa získá perkoláciou rastlinných drog vňate kuklíka městského (Herba caryophyllatae), vňate parnajoránu cbyčajného (Herba origani), vňate zlatobýlu obyčajného (Herba virgaureae) a kvetu klinčekového (Flos caryophylli) zrie,děným liehom, pričom hmotnostný poměr násady k hotovému výluhu je 1:1 a koncentrácia liehu je od 40 do 60 obj. %.The main purpose of the invention is to prepare a composition used for the treatment of inflammation of the tonsils and larynx. The new composition is obtained by percolating the herbal drugs of the herb of the city of the city (Herba caryophyllatae), the herb of the common oregano (Herba origani), the herb of the common goldenrod (Herba virgaureae) and the flower of the clove (Flos caryophylli) with diluted alcohol, whereby the weight ratio of the batch to the finished extract is 1:1 and the alcohol concentration is from 40 to 60 vol. %.
Description
239181239181
Vynález sa týká prostriedku na liečeniezápalov mandlí a hrtana. Prostriedok obsa-huje zmes adstringentných, antiseptických,protizápalových a fytoncídnych látok v zrie-denom liehovom výluhu z rastlinných drog,ako aj ďalšie bližšie neurčené fyziologickyaktivně látky, ktoré posobia stimulačně svo-jlm synergickým účinkom. Prostriedok sapoužívá na výplachy ústnej dutiny vo forměkloktadla.The invention relates to a composition for the treatment of tonsils of the tonsils and larynx. The composition comprises a mixture of astringent, antiseptic, anti-inflammatory and phytonutic agents in the diluted plant extract liquor as well as other non-specified physiologically active substances which will stimulate their synergistic effect. The composition is used to rinse the oral cavity in the form of a collocation.
Na liečenie zápalov mandlí a hrtana sa unás používajú kloktadlá typu Ga-Fo, ktorésa však móže používat len krátkodobo aStopangln s obsahom Hexetidinu, ktorý přidlhšom užívaní dráždi chuťové kanáliky.For the treatment of tonsillitis and larynx, ga-gars of the Ga-Fo type are used, but can only be used for a short time with aStopangin containing Hexetidine, which will irritate the taste canal for longer.
Zo zahraničných kompozitných príprav-kov na báze liečivých rastlín možno spome-núť Cional-Kreussler fy Kreussler (Flor.Chamomillae, Fol. Salviae, Flor. Arnicaej,Echtrose.pt Fy Vogel a Weber (01. Anisi, 01.Foeniculi, Succ. Echinacea purp., Tinct. Ar-nicae, Tinct. Caryophylli, Tinct. Myrhae,Tinct. Rathaniae a inéj, Kamillosan M fyDegussa Ph. Gr. Homburg (Extr. Chamomil-lae, 01. Menthae píp., 01. Bergamottae ainéj, Anginasin Spray fy Opfermann (Hexe-tidin v kombinácii s 01. Rosmarini, 01. Thy-mi, 01. Menthae píp. a ďalšie) a Salviathy-mol fy Galenika Hetterich (01. Salviae, 01.Eucalypti, 01. Caryophylli, Tinct. Myrrhae,Tinct. Ratanhiae, tymol a inéj.Among the foreign medicinal plant-based compositions, the Cional-Kreussler by Kreussler (Flor. Chamomillae, Fol. Salviae, Flor. Arnicaej, Echtrose.pt by Fy Vogel and Weber (01. Anisi, 01.Foeniculi, Succ.) Can be mentioned. Echinacea purp., Tinct. Ar-nicae, Tinct. Caryophylli, Tinct. Myrhae, Tinct. Rathaniae and others, Kamillosan M fyDegussa Ph. Gr. Homburg (Extrem. Chamomil-lae, 01. Menthae Peak, 01. Bergamottae ainéj, Anginasin Spray by Opfermann (Hexe-tidine in combination with 01. Rosmarini, 01. Thy-mi, 01. Menthae and others) and Salviathy-mol by Galenika Hetterich (01. Salviae, 01.Eucalypti, 01. Caryophylli, Tinct Myrrhae, Tinct Ratanhiae, tymol and others.
Tieto přípravky obsahuji! éterické oleje aextrakty z cudzokrajných drog, ktoré sú ná-ročné po spracovateískej aj ekonomickejstránke.These products are included! essential oils and extraneous drug extracts that are both costly and economical.
Tieto nedostatky odstraňuje prostriedokpodl'a vynálezu, kterého podstatou je, že je-ho účinná zložka pozostáva zo zriedenéhotekutého extraktu nasledovných drog: vňa-te kuklíka městského (Herba Caryophylla-tae), vňate pamajoránu obyčajného (HerbaOrigani), vňate zlatobýlu obyčajného (Her-ba Virgaureae) a kvetu klinčekového (FlosCaryophylli) v pomere 1 až 4 : 1 až 4 : 1 až4 : 1. Hmotnostný poměr násady drog k ho-tovému extraktu je 1 : 1.These drawbacks are remedied by the present invention that its active ingredient consists of a dilute liquid extract of the following drugs: include the cervix (Herba Caryophylla-tae), the periwinkle (HerbaOrigani), of the goldenrod (Her- and Virgaureae) and a clove flower (FlosCaryophylli) in a ratio of 1: 4: 1 to 4: 1 to 4: 1. The weight ratio of drug to pot extract is 1: 1.
Na přípravu extraktu sa používá zriedenýlieh o koncentrácii 40 až 60 obj. %, pretožerozpusta takmer všetky terapeuticky vý-znamné látky nachádzajúce sa vo vyššie u-vedených drogách a posobí konzervačně akov zmysle mikrobiologickom, tak i chemie -kom. Extrakt je stály, nerozkládá sa a účin-né látky nepodliehajú hydrolýze ani inýmrozkladným procesom. Vňať kuklíka městského obsahuje euge-nol, triesloviny a flavonoidy, ktoré posobiaantiseptický a adstringentne. Pri vonkajšompoužití slúži droga na výplachy ústnej du-tiny ako dezinfekčně kloktadlo a na odstrá-nenie nepříjemného zápachu z úst. Vňať pamajoránu obyčajného obsahuje é-terický olej s hlavnou zložkou tymolom, kto-rý posobí dezinfekčně a protizápalovo. Vňať zlatobýlu obyčajného obsahuje tries-loviny a flavonoidy, ktoré posobia adsrtin-gentne a fytoncídne. Droga sa používá ajako diuretikum a urologikum, stimuluje lát-koví! premenu, posobí liečebne a detoxikač-ne. Ludové sa uplatňuje zvonka na obkladyna zle sa hojace a hnisavé raný.For the preparation of the extract, dilutions of 40-60% by volume are used, and almost all of the therapeutically important substances found in the above-mentioned drugs are conserved and conserved in both microbiological and chemistry terms. The extract is stable, does not decompose, and the active substances are not subject to hydrolysis or other decomposition processes. The scent of the urban avens contains eugelol, tannins and flavonoids that are posant and adepting. For external use, the oral duo rinse drug serves as a disinfectant gargle and to remove unpleasant odor from the mouth. The periwinkle flavor contains ethereal oil with the main component thymol, disinfectant and anti-inflammatory. The fragrance of the goldenrod contains flavoring agents and flavonoids, which will serve as adsorbents and phytoncids. The drug is used as a diuretic and urologic, stimulating the substance! conversion, healing and detoxification. Ludova applies externally to the cladding of badly healing and purulent early.
Hlavně výhody uvedeného prostriedkuspočívajú v poměrně jednoduchej príprave,využití dostupných liečivých rastlín a nízkejtoxicitě, pričom liečivý účinok je zrovnateí-ný s vyššie uvedenými známými přípravka-mi.In particular, the advantages of said composition are in relatively simple preparation, utilization of available medicinal plants and low toxicity, wherein the healing effect is comparable to the aforementioned known formulations.
Akútny zápal podnebných mandlí (akút-na tonzilitída) a akútny zápal hrtana (akút-na faryngitída) patria medzi najčastejšiechoroby horných dýchacích a zažívacíchciest, pričom v popředí bývá izolovaný zá-pal mandlí (tonzilitída). Liehový extrakt voformě kloktadla (3X denne 15 až 20 kva-piefc rozpuštěných v 100 ml vlažnéj vody)bol podávaný skupině 30 pacientov s diagnó-zou akútna faryngitída a akútna tonzilitídavo veku od 20 do 60 rokov v počiatočnýchštádiách nemoci. Už po niekolkých poda-niach sa pacienti cítili subjektivné lepšie,ustúpili bolesti v krku a znížilo sa prekrve-nie hltanovej úžiny. Po 5- až 7dňovom podá-vaní přípravku příznaky choroby pominuli. Ďalej sú uvedené příklady přípravy pro-striedku podl'a vynálezu. Příklad 1Acute tonsillitis and acute inflammation of the larynx (acute to pharyngitis) are among the most common diseases of the upper respiratory tract and digestive tract, with tonsillitis being isolated in the foreground. The alcohol extract in the gargle form (3X daily 15-20 kVA) dissolved in 100 mL lukewarm water was administered to a group of 30 patients diagnosed with acute pharyngitis and acute tonsillitis aged 20 to 60 years in the early stages of the disease. Already after several administrations, the patients felt subjective better, withdrew from sore throats and reduced the blood flow of the pharynx. After 5- to 7-day administration, the symptoms of the disease have disappeared. The following are examples of preparation of the composition according to the invention. Example 1
Na 1 0Π0 g tekutého extraktu sa použijeperkolátor s obsahom 6 až 7 L. 1 000 g ná-sady drog skladajúcej sa z 300 g Herba ca-ryophyllatae, 300 g Herba origani, 300 gHerba virgaureae a 100 g Flos caryophyllisa prevlhčí s 500 g 60% liehu. Potom sa per-koluje 60% liehom sposobom uvedeným vPhBs III str. 615. Získá sa tak 1 OOO g teku-tého extraktu na priamu aplikáciu. Příklad 2 1 OOO g tekutého extraktu získáme zmieša-ním 300 g extraktu Herba virgaureae fluidi(1:1), 300 g extraktu Herba origani fluidi(1:1), 300 g extraktu Herba caryophyllataefluidi (1:1) a 100 g Tinctura caryophylli(1:10).For 10% of the liquid extract, use a centrifuge containing 6 to 7 liters. 1000 g of drug additive consisting of 300 g of Herba caophyllata, 300 g of Herba origani, 300 g of Herba virgaureae and 100 g of Flos caryophyllisa moisten with 500 g 60 % alcohol. Thereafter, 60% alcohol was passed through the process described in PhBs III p. 615 to obtain 1000 g of liquid extract for direct application. Example 2 1000 g of liquid extract are obtained by mixing 300 g of Herba virgaureae fluidi extract (1: 1), 300 g of Herba origani fluid extract (1: 1), 300 g of Herba caryophyllataefluidium extract (1: 1) and 100 g of Tinctura caryophylli (1:10).
Prostriedok podl'a vynálezu je tekutinatmavoi hnědá, výraznej tymiánovej a klinče-kovej vóne a zvieravej chuti. S vodou samieša bez zákalu. Obsah alkoholu je najme-nej 40i%. Z účinných látok přítomných vextrakte bol stanovený eugenol, tymol, tries-loviny a flavonoidy. Pyrolizidínové alkaloi-dy v extrakte neboli dokázané. Extrakt jestály, ak sa uchovává v nádobách dobré u-zavretých, pri obyčajnej teplote, chráněnýpřed svetlom.The composition according to the invention is a liquid dark brown, pronounced thyme and clinker, and an appetizing taste. With water samiea without cloudiness. The alcohol content is at least 40%. Of the active ingredients present in the extract, eugenol, thymol, tannins and flavonoids were determined. Pyrolizidine alkaloids in the extract have not been proven. The extract was present when kept in containers well sealed, at room temperature, protected from light.
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CS8310299A CS239181B1 (en) | 1983-12-30 | 1983-12-30 | An agent for the treatment of tonsillitis and larynx |
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CS8310299A CS239181B1 (en) | 1983-12-30 | 1983-12-30 | An agent for the treatment of tonsillitis and larynx |
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CS239181B1 true CS239181B1 (en) | 1985-12-16 |
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