CS222957B1 - Indication tube for detecting urea - Google Patents
Indication tube for detecting urea Download PDFInfo
- Publication number
- CS222957B1 CS222957B1 CS786445A CS644578A CS222957B1 CS 222957 B1 CS222957 B1 CS 222957B1 CS 786445 A CS786445 A CS 786445A CS 644578 A CS644578 A CS 644578A CS 222957 B1 CS222957 B1 CS 222957B1
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- μοιλη
- urease
- bands
- indicator
- tube
- Prior art date
Links
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title claims 2
- 239000004202 carbamide Substances 0.000 title claims 2
- 108010046334 Urease Proteins 0.000 claims 3
- 238000001514 detection method Methods 0.000 claims 1
- 150000002772 monosaccharides Chemical class 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 101500021172 Aplysia californica Myomodulin-C Proteins 0.000 description 1
- -1 amino- Chemical class 0.000 description 1
- 230000029305 taxis Effects 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/521—Single-layer analytical elements
- G01N33/523—Single-layer analytical elements the element being adapted for a specific analyte
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/58—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving urea or urease
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Description
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H3JIO3CBHKE CYIUHOCTH H30BPETEHHH
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Tax xax BH^exeHHe rasa προτβχββτ Ηβ xHHeftHoS saBHCHMocThro οτ xo-ΧΗΠβΟΤΒΘ ΜΟηβΒΜΗΗ, HHflHXaTOpHBie ΟΗΓΗΘΧΒΗΗβ SOHH ΒΗΠΟΧΗβΗΗ ΪΪΛΗ TaX,hto ohh cooTBeTCTByroT npoueccy, hxh xaamax 3OHa oópaaoeaHa ApyrnsíCOOTBeTCTByratMM ΗΗχΗΧθΤΟρΟΜ HJIH χοδβΒΛβΗΗβΜ ΟρΓβΗΗΗβΟΧΟίί XHCXOTH,XJTO ytIHTHBaeTCfl 9ΤΟ OÓCTOHTeXbCTBO · 4
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HanbHOfí ΛβΗΤΗ. ΠγΤβΜ ΛθΛβΗΜΗ MHflHKaTOpHHX SOH Ha ΟΚΓΗ&ΚΒΗΗβ 30HH M3 ρβ8ΛΗΗΗΗΧnojioc y^ynnúSeTca oijeHxa ΗβοπυτΗΗΜ nepcoHanoM.
MapKHpOBKa MH^HKaTOpHHX CMrHSJIbHHX SOH C pa8JIHqHHMM, ΠΟΠβρβΜβΗ-ho HaBeceHHHMH zHflMKaTopaMH jjaeT ayHmwx πΒβτοβοίί xoHTpacT, oC-aernaeT oneHKy h .neaaeT ee τοπΗββ. MH^MKaTopnaH noaoca OTjnmaeTca Aaaee τβΜ, hto Haxoflamaftca bpeaKKHOHHoň aoHe καα οπρβΛβΛβΗΜΗ μοηθεμηκ npenapai* ypeasa co^ep-xht AOÓasxy MOHOcaxapíifla οτ 1 ao 15%, npeMMymecTBeHHO ruiBKOsy. IIpenapaTH ypeaaH, κοτορκβ Ηβ ηβληβτοη CBepxHHCTHMH, HanpHMep,cupaa ypeasa, cooTBeTCTByionjax ",'/orthington Enzimes for Reaserch", κβτβΛΟΓΗ qeH 1967, CTp. 17 μλμ 1970, CTp. 20 /lort-hington Eiochemical Corporation, Freehold, New Jersey, USA /, b κοτορυχ ΛβΗΒΐ τρκ xanecTBa : BHcrnee c οτ 1500 qo 2000unita / wr, cpeflHee c 12Q units / μγ h cupaa ypeaaa c 50unita /μγ, κοτορκβ yqoaaeTBopamT Haninu τρβδοΒβΗΗΗΜ, πρκΒο-Λητ πρκ HaHeceHMM Ha xocnTejxb, očaaqammHS BnMTHBaBmeii cnocoó-HOCTbSJ X ΤΗ^ρΟφοδΗββΐχΗΗ ΤβΚ, ΗΤΟ ρβθΧΠΗΟΗΗβΗ 30Η3 ΜΟΧβΤ ΒΠΜΤΗ-BSTb CHBOpOTKy m KpOBb Ηβ ΛΟΟΤβΤΟΗΗΟ ĎHCTpO. ^ΟδθΒΚβ ΜΟΗΟΟβΧβ-ΡΗΛΟΒ yCTpaHfl«T 8Τ0Τ ΗβΛΟΟΤβΤΟΧ Η ΟΛΗΟΒρβΜβΗΗΟ ΒΛΗΗβΤ ΟΤθδΗΛΜ-SHpymme Ha ycTO&nuBOCTb φβρΜβΗτποδ θκτμβηοοτμ πρη xpaHeHnn β ΗορΜβΛΒΗΗΧ yCJTOBHHX. ΧρβΗβΗΗβ Β ΧΟΛΟ,ΖζΜΛΒΗΗΚβ Ηβ Tpe6yeTCH. ΜΗ£ΗΧβΤΘρΗ8Η ΠΟΛΟ Ca ΟΤΛΗΗββΤΟΗ ΤβΜ, ΗΤΟ ρββΚΙξΗΟΗΗβΛ 30Ηβ ΗβΗΜββΤ Čy$epM8aHHH, Ηβτ £θ6βΒΧΗ ΐςβΛΟΗΗΟΓΟ ΧββΟΗΘΤβ η/μλη ΓΗΛΡΟ-orbck ιηβΛΟΗΗΟΓΟ ΜβτβΛΛβ η coqepxnT uajxooHiReHHyx) ypeaay· 3τημ Μοχβτ ÓHTb jjocTíirHyTO coxpaiqeHHe peaxqnoHHoro BpeueHH 6es©ΓρβΗΜΗβΗΜΗ TOHHOCTH. 5 ΠΡΚΜΕΡ OCyiUECTBJIEHHfl Π3ΟΒΡΒΤΕΗΗΗ ΜβοδρβτβΗΗβ oÓtHCHfieTCfl no^poóHee Ha ΟΛβΑγκπξΜΧ npraiepax. OTHOcamHftcH ciofla ηβρτβχ noKa3H«aeT: φΗΓ. 1: TpyČKa-HHflHKaTop c ocTawnicfl ποοτοηηηημ BHyTpeHHHMΑΗΘΜβΤρΟΜ ΚΘΠΜΛΛΗρΗΟίί TpyÓKH, φΗΓ. 2: TpyČKa-HHflMKaTop c nacTHHHo yBexHHeHHHM BHyTpeHHHMΛΗβΜβΤρΟΜ ΚβΠΗΛΛΗρΗΟίί TpyÓKH. ΠρπΜβρ 1 &JUI ΚβΠΗΛΛΗρΗΟΜ TpyÓKM, Η300ρβΧβΗΗ0& Ha φΗΓ. 1, BHĎpaH ΚβΠΗΛ- jrsp H3 οηητοτηηβοκογο ΜβτβρκβΛβ c BHyTpeHHHM ΑΗβΜβτροΜ 2,5 mm Μ ΛΛΜΗΟϋ 60 MM, KOTOpHÍÍ ΗΜββΤ MapKHpOBKy 2 B 4 MM . &IH HH£HKa- TOpHOS ΟΗΓΗβΛΒΗΟΠ ΛΘΗΤΗ 3 BHČpaH φΗΗΒΤρΟΒβΤβΧΒΗΗϋ KapTOH C ΒβΟΟΜ2 βΛΗΗΗΗ&ι noeepxHOCTH 200 γ/μ . PeaKHHOHHan apna 4 HMnperHHpoeaHacjie^ysu^HM oópaaoM : ypeasa, MSJíoomtmeHHaH 100 μγrxroKoaa 1 r BO^a #ecT. r 10 mjx
KaHT φΗΛΒΤρΟΒβΛΒΗΟΓΟ KapTOHa ίΠΗρΗΗΟδ B 20 MM OKyHSUOT B 9TOTpacTBop. Cpaay ate nocxe θτογο Ha 3Ty peaKHHOHHy® cHCTeMy 4ΗΘΤΗΓΗΒβΙΟΤ nOXOCKy ΠΙΗρΗΗΟϋ 4 MM 20% —ΗΘΓΟ paCTBOpa CTeapHHOBOSκηολοτη b qeTHTexxaopHCTOM yrzepo^e. 3τβ γθλροΦο6η38ηηοηη8ηaoHa npe.no apaqaeT προημκηοβ6ηηθ HccjienyeMoft xhakocth b ηη^ηκθ-τορΗΗβ cHrHajrbHue sohh 5. Οηθ Μοχβτ Chtb βυποΛΗβΗβ no pasHOMyC MSBeCTHHM ΓH1^poφo6H8HpyM)I^HMH CpenCTBBMH AJlfl ΤβΚΟΤΗΛΗ ΗΛΗ 6y-ΜβΓΗ Η ΠΘ CBOeft ΠΙΗρΚΗβ KQXeOdTbCH MeX#y 2 Η 5 MM· ΟΑΗΟΒρβΜβΗΗΟC paCTBOpGM ypea3H H ΓH,^pOφOÓH3HpyEΠ^HM paCTBOpOM HaHGCHTCfl HH-flHKaTOpHUe ΟΗΓΗβΛΒΗΗβ 3ΟΗΗ 5 ΠΟΒβρΧ ΓΗηρθφθ6Η3βηΗΟΗΗΗΧ 3OH cor-jiacHo npHMepaM 2 - 4. Jlx pacnoaoaeHHe ©npenezaeTCfl τβ,. κβκοβonpenefleHze λολχηο 6mtb npose^eHo, noxyKOJiHHecTBeHHoe ηλη kojih-necTBeHHoe. 6 ΠΟΑΓΟΤΟΒΛβΗΗΗΜ TaKMM OČpaSOM φΜΛΒΤρΟΒβΤβΛΒΗΗίί ΚβρΤΟΗ Η3ρβ3βΚΤySXHMM ΟΗΓΗΘΛΒΗΗΜΗ ΠΟΛΟΟΚΘΜΗ 3. Πο Μβρβ Ha^OÓHOCTH HHflHKaTOp-Hym curHaabHy® soay 3 bctwiabt b KaniuijiapHyio TpyÓKy 1.
Ecjik floazna ÓiiTb ocymecTBaeHa προββρκβ Ha MoneBHHy, το ηηλη-κβτορΗγτο cwrHajibHyro aeHTy 3 βντηγηβ8®τ Haeepx Haa ΜβρκΗροβκοίί2 npMČJI. Ha 10 MM. MapKWpOBaHHhlft ΚΟΗβΡ ΚβΠΗΛΛΒρΗΟδ TpyÓKH 1OKyHamT b npoaepaeMyy xhakoctb. Ecan HanoaHeHHe caynaíiHo npon-8ΟΙΠΛΟ Bmne MapKHpOBKH 2, ΤΟΓ£β Η3ΛΜΙΠΗββ ΚΟΛΗΗβΟΤΒΟ ZHflKOCTMOCTOpQZHO CHHM81DT IIOJIOCKOft φΜΛΒΤρΟΒβΤβΛΒΗΟ^ ÓyMarW Μ T8KHM oó-pasoip oho ycTaHSBjmBaeTCH aerxo η tohho. BuTarMBaHMeM HasaAΜΗ,ΣξΗΚβτορΗοίί οηγηθλβηοΑ ΛβΗτκ 3 Ha itapKHpoBKy 2 HannHaeTca on-pefleaeHKe. PeaKpME npoBO^HT πρκ 25°C m nepes 15 mhh. nponsBo-ΛΗΤ oiíeHKy. ΠρΗΜβρ 2
BpHJIJIHaHTOBHŽ SeJXTHM 10 ΜΓ
ΘΤΘΗΟΛ 10 MZ
PlHAHKaTopHHií pacTBop HaHOCHT na noaocxy, nmpnHoíi 2-3 mm, nosepxΓΗ,ςροφο6Η38ΐριθΗΗθ& 30HH tsk, htoÓh eceraa ocTaBajiacb npoMezyTon-Haa 3OHa nmpHHoft 1 - 2 mm. C 3T0íí ΗΗΛΗΚβτορΗοϋ οηγηολβηοΛ aeHTOft3, KOTopaa coaepzHT 5 ηηαηχβτορηηχ οηγη&λβηηχ soh 5, προηθβολητΟΠρβΛβΛβΗΜβ ΚρΟΒΗ HZ Η CHBOpOTKH npH 25°C Β ΚΘΠΗΖΖΗρβ 1, ΚΘΚ ΟΠΗ-caHo β npHMepe 1, τα nepea 15 μηη. προβοζητ opeHKy.
Ilepsys oijeHKy noBumeHHHX κοΗηβΗτρβηπβ μθζηο ocymecTBHTb nepas5 MZHyT. Kazzaa HHZHKaTopHaa sohs 5 cooTBeTCTByeT no ycTSHOB—zeHHoS nmpHHe h ycTaHOBzeHHoft npoMezyTonHoS ποΒβρχΗοοτΜ onpeze-zeHHOuy KoznnecTBy monesmhh. 3HaneHMa κ STOMy οηκτβκ>τοΗ c πρκ-ΖΟΖβΗΗΟϋ TaĎZHIÍH HZ H MOPyT ÓHTb ΟΤΠβηβΤβΗΗ Ha ΠΟΖΟΟΚβ ΤΑΧΙΑ ΚΒΠ1ΑΧ-ΛΗρβ. ΠρΗΜβρ 3 B KanecTBe KanazzapHoft TpyÓKH 1 npHMeHaBT KanMzzap corzacno npHMepy 1. 7
pacTBop a) 6pOMKpe3OJIOBHH 3βΛβΗΗΜ ΒΗΗΗβΛ KHCJIOTa ΘΤΘΗΟΛ 40 μγ 100 μγ 10 MJI pacTBop 6) ĎpmtJIMaHTOBHÍi ΧβΛΤΗϋ 3T aHOJl 40 μγ 10 MJI
Tskhm oCpaaoM naroTOBJíeHHue ΗΗΛΜΚβτορΗΗβ pacTBopu hhhocíit no-eepx rimpo$oÓMaaiíit©HHOÍi 3ohh b caeayraneM nopnaice : 1. ΗΗ^ΗκβτορΗβΗ cHrnajibHáH aoHa pacTBopa a) npoMexyTOHHan aoHa 2 ao 3 um mHpHHH 1 MM 2. HHflHKaTopHaa cHrHajtbHaH aoHa pacTBop 6) npoMexyTOHHaa aoHa 2 flO 3 MM IHHpHHH 1 MM 3. HH^HKaTopHaH cHrHaztbHaH aoHa pacTBop a) npoMexyTOHHaH aoHa 2 flO 3 MM nrapHHa 2 MM 4. ΗΗβΗΚΘΤΟρΗβίΙ CHrHaJIbHaH 3ΟΗΘ paCTBOp β) npoMexyTOHHajj a©Ha 2 flo 3 mm mHpHHB 3 MM 5. ηη^ηκθτορηθη οηγηθλβηηη sona pacTBop a) 4 2 £0 3 MM ΙΠΗρΗΗΗ IIpoMexy το traste 3ohsi 6 MoryT HMeTb Taxym xe nmpiray, Kate η ηηλη-κβτορΗΗβ cHrHajtbHsie 3ohu 5, ho MoryT ÓstTb ΒΗδρβΗΗ h apyruMM.Πο hx ycTaHOBKe Ha^o jxaeaTb οοοτΒβτοτββΗΗο aHanenne Ha xaniui-jtnpe 1, mjiií ΗΗ^ΗκβτορΗο^ cHrHazibHoft jteHTe 3, jum TaČJtnne· npHMeHene ΜΗ,χκκβτορβ, Μ3ΜβΗΗΐοιςβΓθ ρββτ b KpacHHíí, αλη βτοροϋMHflHKaTOpHOÍÍ ΟΜΓΗβΛΒΗΟΚ 30HH flOJIXHO ΟΗΓΗΘΛΗβϊίρΟΒβΤΙ» ΗβΗΘΛΟ ΠΟΒΒΠΠΘΗΗΟΓΟ 3Η8ΗθΗΗΗ ΜΟΗβΒΗΗΗ-θβΟΤβ· ΡββΚρΜΚ) ΠρΟΒΟ^ΗΤ ΠρΗ 25°Cnepea 15 MHHyT προηθβολητ oiíeHxy. 8 ΠρΗΜβρ 4
BpoMKpesojiOBHÍí aeJieHHiíB ΜΗ ΗΘΗ ΚΗΟΛΟΤβ
3T8HOJI 30 ΜΓ60 ΜΓ10 ΜΛ PIsaeCTHHM CnOCOĎOM ΠρΜΓΟΤΟΒΛβΗΗΗϋ ΗΗβΗΚ aTOpHNÍí paCTBOp HaHOCHT-CH Ha ΟΗΓΗβΧΒΗΗβ 3OHH 5 HIHpHHOfó 1 flO 3 MM C paSJtHtlHMMH pacCTO-hhkhmh flpyr ot apyra nosepx rM£po$oÓH8aiíMOHHOií bohu. npOMexy-To^Haa 80Ha 6 n hhcxo ΜΗ^ΜΚβτορΗκχ οκγηθλβηηχ soh 5 οπρβΛβχηκτtohhoctí» h onpeflejifieMoe KOJnmecTBO. Ecjih Mes#y 1-fí h 2-S οηγη^λβhhmh sohsmh ycTHHOBjíeHo paccTOHHHe i 1 uu, Mex^y 2-S H 3-& - pacCTOHHMe b 2 mm η Mex^y 3-ft h 4-ft-paccTOHHHe b 4 mu, to nepsáncurHasbHan soHa ποκββΗβββτ, ΗβπρΗΜβρ, λο 20 μγ MoneBunu/aaoTa.Βτορβη curH&ffbHan aoHa noKasMBaei* 30 ur uoqeBMHu/aaoTa, τρβτΒΗcHrHaabHan soHa - 45 μγ uoneBHHu/a3OTa η ηβτΒβρτβη -60 μγ Mone-BHHM/aaoTa. ΠρζΜβΗΗκτ cornacHO φΗΓ.2 Kanaxxap c pacraupeHHHM ρββκςιιοΗΗΗΜnpocrpaHCTBOM 7, κοτοροβ ΗΜββτ AffHHy 10 mm b npe^exax uapKHpo-BRH H ΗΜββΤ BHyTpeHHHft ΛΗΘΜβΤρ 2,5 UM. K dTOMy npMCOe^MHHeTCHnacTb jíJXHHoft 30 mm m BHyrpeHHHu ΛΗβΜβτροΜ 7 um η ββτβΜ cxe^yeTqaďb Kanonnnpa 20 um fíxvino& h BHyTpeHHHM flHaueTpou 2,5 mu.PeaKHMa coKpamaeTca Ha 7 uKHyr. ΦΟΡΜΟΑ Μ30ΒΡΕΤΕΗΚΗ
TpyÓKa-HimHKaTop rxx onpeRejiennsi ΜΟΗβΒΗΗΗ c πομο^β© ypea3H, HaMHfliiKaTopHoft carHajibHoa ΛβΗτβ κοτοροδ pacnojioseHH o^Ha ηλη Hec-KOJIBKO MHflHKaTOpHHX ΟΗΓΗΘΛΒΗΜΧ 3OH Β BH£6 ΠΟΛΟΟΟΚ, ΗΗβΗΚβΤΟρΟΜκοτορυχ ΗΒΛΗΘΤΟΗ ΜβΗΗΜ(Η& ΙξΒβΤ B ΐηβΛΟΠΗΟϋ ορβΛβ KpaCHTCJIb, ΟΤΛΗ-qa©mastcfl ΤβΜ, ΗΤΟ Ha HHflHKaTOpHOÍi ΟΗΓΗΘΛΒΗΟβ ΛβΗΤβ (3), Haxoflfl-meftCH Β ΒΗΠΟΛΗβΗΗΟίί Β ΒΗ^β ΠΜΠβΤΚΗ ΚβΠΜΛΛΗρΗΟϋ TpyÓJie (1), pac-ποΛΟΛβΗβ nacTb Heóy$epHoii, cboÓo^hoS ot mejiOHHoro icapČOHaTa -m/OM ΠξβΛΟΠΗΟβ ΓΗΛΡΟΟΚΗΟΚ ρββΚίχΗΟΗΗΟδ CHCTeMH (4) H3 ΜβΛΟΟΗΗΠφΗ-hoS ypeaaH κ οτ 1 ío 15% MOHOcaxapH.ua, h npoMeacyroHHHe οτρββκκ(6) HHflHKaTOpHHX 30H (1) HMCKT QHpMHy OT 1 RO 10 MM.
AHHOTAW ΜθοδρβτβΗκβ KacaeTCH τργΰκκ-ΜΗΛΜΚβτορβ ^λη οπρβΛβΛβΗΜΑ uone-BKHH M OTHOCMTCfl K MH^MKaTOpy OJISI δΖΟΧΜΜΜΧΙβ CKMX ρβθΚρΜΜ.
Ue2b Μ3θδρβΤβΗΗΗ 38KJimaeTCH B TOU, WTOÓN paSpaÓOTSTb TpyÓKH“ΗΗΑΗΚΘΤΟρ, κοτορϋδ CJiyXHM 6n OTÓOpa pacenHTaHHOrO ΚΟΛΜΠβ- CTBa KpOBM Win CMBOpOTKM ΪΙ3 OpraHMSMa M RBJl On BOSMOXHOCTb Bκοροτκοβ Bpeua cflexaTb noxyKOJixnecTBeHHoe m κοΛΜπβοτΒβΗΗοβaaKjiro^eHMe o coAepxaHMH MoqeBKHH-asoTa b kpobm. 3ajj;ana pemaeTCH Teu, bto μη^μκθτορηηη οηγηθλβηβη λθητθ, ηηχολη-iqaflCH B ΒΗΠΟΛΗβΗΗΟβ B ΒΜ£β ΠΜΠβΤΚΜ ΚβΠΜΛΛΗρΗΟβ TpyČKe, COflepKHTΗβδγφβρΗγΒ CBOÓOflHyB OT ΠΙβΛΟΒΗΟΤΟ ΚβρβΟΗβΤβ Ϊΐ/ΚΛΜ ΠξβΛΟΒΗΟϋ ΓΟ^ρΟokmch peaKBBOHHys) cucTeuy ks uanooBMnieHBoS ypeasu μ 1 flo 15% uo-HocaxapMa, z npoueatyTOtiHse οτρββκκ ηηαηκβτορηήχ soh iímesyř mz-pzHy OT 1 ro 10 uu. ΗβΟδρβΤβΗΚβ npKMeHHMO B ΚΛΗΗΜΉβCKOfi βΗβΓΗΟΟΤΗΚβ, B ΟΠΘΟβΤβΛΒΗΟβcjiyxóe n ajxh aMČysaTopHHX Bpa^eS. ΪΙδΟδρθΤβΗΗβ nOflpOĎHO ΠρββΟΤβΒΛβΗΟ ΗΘ pZCyHKe 1.
Claims (1)
- " /// ' PŘEDMĚT VYNÁLEZU Indikační trubka pro zjišťování močoviny pomocí ureasy,na jejíž indikační signální pásce je umístěno jedno nebo ně-kolik indikačních signálních pásem v podobě pruhů, jejichž in-dikátorem je barvivo měnící barvu v alkalickém prostředí, vy-značující se tím, že na indikační signální pásce (3), umístěnév kapilární trubce (1) tvaru pipety, je část reakční soustavy(4) z málo vyčištěné ureasy a od 1 do 15 % monosacharidu a me-zilehlé úseky (6) indikačních pásem mají šířku od 1 do 10 mm· 1 výkres Uznáno vynálezem na základě výsledků expertizy, provedenéÚřadem pro vynáleze©tví a patentnictví, Berlín, DD
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DD20187377A DD137384B1 (de) | 1977-11-04 | 1977-11-04 | Indikator-kapillar-roehrchen zur harnstoff-bestimmung |
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| Publication Number | Publication Date |
|---|---|
| CS222957B1 true CS222957B1 (en) | 1983-08-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS786445A CS222957B1 (en) | 1977-11-04 | 1978-10-04 | Indication tube for detecting urea |
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| US (2) | US4252903A (cs) |
| BG (1) | BG36593A1 (cs) |
| CH (1) | CH635939A5 (cs) |
| CS (1) | CS222957B1 (cs) |
| DD (1) | DD137384B1 (cs) |
| DE (1) | DE2843485A1 (cs) |
| FR (1) | FR2408144A1 (cs) |
| GB (1) | GB2007838B (cs) |
| HU (1) | HU179400B (cs) |
| SE (1) | SE7811419L (cs) |
Families Citing this family (21)
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| JPS5670460A (en) * | 1979-11-13 | 1981-06-12 | Fuji Photo Film Co Ltd | Multilayer chemical analysis material for analysis of water liquid |
| AU547596B2 (en) * | 1980-12-19 | 1985-10-24 | Minnesota Mining And Manufacturing Company | Test method and article for estimating the concentration of free acid in liquid |
| US4654309A (en) * | 1980-12-19 | 1987-03-31 | Minnesota Mining And Manufacturing Co. | Test method and article for estimating the concentration of free acid in liquid |
| IT1205338B (it) * | 1983-08-09 | 1989-03-15 | Miles Italiana | Composizione e metodo per la determinazione enzimatica di urea in liquidi organici |
| US4973549A (en) * | 1987-06-22 | 1990-11-27 | Chemtrak Corporation | Quantitative diagnostic assay employing signal producing agent bound to support and measuring migration distance of detectable signal |
| GB8714979D0 (en) * | 1987-07-02 | 1987-08-05 | Rayman G A | Testing fluids |
| AU1816888A (en) * | 1987-06-26 | 1989-01-05 | Gerrard Abdool Rayman | Device for testing fluids |
| WO1989006792A1 (en) * | 1988-01-21 | 1989-07-27 | Boehringer Mannheim Corporation | Method and apparatus for analyte determination |
| EP0339331A3 (de) * | 1988-04-29 | 1990-09-19 | ARZNEIMITTELWERK DRESDEN GmbH | Teststreifen zur Bestimmung von Harnstoff und seine Anwendung |
| US5100620A (en) * | 1989-05-15 | 1992-03-31 | Miles, Inc. | Capillary tube/gap reagent format |
| US5212060A (en) * | 1990-04-27 | 1993-05-18 | Genesis Labs, Inc. | Dry test strip comprising a dextran barrier for excluding erythrocytes |
| DE59610885D1 (de) * | 1995-10-13 | 2004-02-05 | Crompton Vinyl Additives Gmbh | Stabilisatorkombinationen für chlorhaltige Polymere |
| ATA195796A (de) * | 1996-11-08 | 1999-02-15 | Buchrucker Karlheinz Mag | Testeinrichtung zum harnstoffnachweis in milch |
| US5948695A (en) * | 1997-06-17 | 1999-09-07 | Mercury Diagnostics, Inc. | Device for determination of an analyte in a body fluid |
| BR9813307A (pt) * | 1997-10-27 | 2000-08-22 | Idexx Lab Inc | Dispositivo e métodos para determinação de analisado em uma solução |
| US6773898B1 (en) * | 2002-09-09 | 2004-08-10 | Raven Biological Laboratories, Inc. | Process challenge device |
| US7378054B2 (en) * | 2004-04-16 | 2008-05-27 | Savvipharm Inc | Specimen collecting, processing and analytical assembly |
| WO2009143601A1 (en) | 2008-05-27 | 2009-12-03 | Zbx Corporation | Enzymatic analytical membrane, test device and method |
| GB201400115D0 (en) * | 2014-01-05 | 2014-02-19 | Gerardos Georgios | Multiple ligands detection using an immunoassay device |
| EP3813908A4 (en) | 2018-06-28 | 2022-04-20 | Rand, Kinneret | NON-CLOGGING AND ANTI-ADHESIVE MICROCAPILLARY NEEDLE WITH IMPROVED TIP VISIBILITY |
| US10765793B1 (en) | 2019-06-27 | 2020-09-08 | Fresenius Medical Care Holdings, Inc. | Ammonia detection in dialysis systems |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL101441C (cs) * | 1959-03-13 | |||
| US3249513A (en) * | 1963-09-19 | 1966-05-03 | Warner Lambert Pharmaceutical | Purification of urease |
| FR1447191A (fr) * | 1964-03-20 | 1966-07-29 | Boehringer & Soehne Gmbh | Matériel de diagnostic pour la détermination des substances contenues dans le sang entier |
| NL6509361A (cs) * | 1964-07-20 | 1966-01-21 | ||
| FR1472956A (cs) * | 1964-07-20 | 1967-06-01 | ||
| US3768978A (en) * | 1971-03-01 | 1973-10-30 | Hamilton Co | Disposable pipette |
| ZA733612B (en) * | 1972-10-11 | 1974-04-24 | Merck Patent Gmbh | Container for test strips |
| ZA733611B (en) * | 1972-10-11 | 1974-04-24 | Merck Patent Gmbh | Indicator for the determination of urea |
| US3950226A (en) * | 1974-10-31 | 1976-04-13 | Moon Ki Chang | Novel reagent and method for the determination of urea in biological fluids |
| CA1054034A (en) * | 1975-06-20 | 1979-05-08 | Barbara J. Bruschi | Multilayer analytical element |
| US4094647A (en) * | 1976-07-02 | 1978-06-13 | Thyroid Diagnostics, Inc. | Test device |
| DE2711634A1 (de) * | 1977-03-17 | 1978-09-21 | Riedel De Haen Ag | Testvorrichtung zur bestimmung von harnstoff in fluessigkeiten |
-
1977
- 1977-11-04 DD DD20187377A patent/DD137384B1/de not_active IP Right Cessation
-
1978
- 1978-10-04 CS CS786445A patent/CS222957B1/cs unknown
- 1978-10-05 DE DE19782843485 patent/DE2843485A1/de not_active Withdrawn
- 1978-10-09 BG BG7841035A patent/BG36593A1/xx unknown
- 1978-10-23 CH CH1095278A patent/CH635939A5/de not_active IP Right Cessation
- 1978-11-02 HU HU78AE547A patent/HU179400B/hu unknown
- 1978-11-03 US US05/957,358 patent/US4252903A/en not_active Expired - Lifetime
- 1978-11-03 GB GB7843150A patent/GB2007838B/en not_active Expired
- 1978-11-03 SE SE7811419A patent/SE7811419L/xx unknown
- 1978-11-06 FR FR7831358A patent/FR2408144A1/fr not_active Withdrawn
- 1978-12-22 US US05/973,075 patent/US4248973A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB2007838B (en) | 1982-05-26 |
| DD137384A1 (de) | 1979-08-29 |
| DE2843485A1 (de) | 1979-05-10 |
| SE7811419L (sv) | 1979-05-05 |
| BG36593A1 (en) | 1984-12-16 |
| DD137384B1 (de) | 1981-07-29 |
| US4248973A (en) | 1981-02-03 |
| GB2007838A (en) | 1979-05-23 |
| FR2408144A1 (fr) | 1979-06-01 |
| HU179400B (en) | 1982-10-28 |
| US4252903A (en) | 1981-02-24 |
| CH635939A5 (de) | 1983-04-29 |
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