CS199693B2 - Způsob výroby derivátů thiazolidin-, thiazana morfolinkarboxylových kyselin - Google Patents

Způsob výroby derivátů thiazolidin-, thiazana morfolinkarboxylových kyselin Download PDF

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Publication number
CS199693B2
CS199693B2 CS777853A CS785377A CS199693B2 CS 199693 B2 CS199693 B2 CS 199693B2 CS 777853 A CS777853 A CS 777853A CS 785377 A CS785377 A CS 785377A CS 199693 B2 CS199693 B2 CS 199693B2
Authority
CS
Czechoslovakia
Prior art keywords
acid
ethyl acetate
formula
salt
carbon atoms
Prior art date
Application number
CS777853A
Other languages
Czech (cs)
English (en)
Inventor
Miguel A Ondetti
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of CS199693B2 publication Critical patent/CS199693B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
CS777853A 1976-12-03 1977-11-28 Způsob výroby derivátů thiazolidin-, thiazana morfolinkarboxylových kyselin CS199693B2 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74728176A 1976-12-03 1976-12-03

Publications (1)

Publication Number Publication Date
CS199693B2 true CS199693B2 (cs) 1980-07-31

Family

ID=25004426

Family Applications (1)

Application Number Title Priority Date Filing Date
CS777853A CS199693B2 (cs) 1976-12-03 1977-11-28 Způsob výroby derivátů thiazolidin-, thiazana morfolinkarboxylových kyselin

Country Status (5)

Country Link
BE (1) BE861454A (fr)
CS (1) CS199693B2 (fr)
HU (1) HU175671B (fr)
SU (2) SU786895A3 (fr)
ZA (1) ZA777062B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4220791A (en) 1979-03-08 1980-09-02 E. R. Squibb & Sons, Inc. Mercaptoacylpyrazolidinone carboxylic acid derivatives
US4211786A (en) * 1979-03-08 1980-07-08 E. R. Squibb & Sons, Inc. Mercaptoacyldihydropyrazole carboxylic acid derivatives
US4221804A (en) * 1979-09-27 1980-09-09 Rovnyak George C Mercaptoacyldihydropyrazole carboxylic acid derivatives
US4254267A (en) 1979-10-25 1981-03-03 E. R. Squibb & Sons, Inc. Mercaptoacyldihydropyrazole carboxylic acid derivatives
US4308392A (en) 1979-12-03 1981-12-29 E. R. Squibb & Sons, Inc. Hydroxamic acid derivatives of mercaptoacyl amino acids
US4284561A (en) 1979-12-03 1981-08-18 E. R. Squibb & Sons, Inc. Hydroxamic acid derivatives of mercaptoacyl amino acids
US4321392A (en) * 1980-02-06 1982-03-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4-oxazolidine-carboxylic acids
US4482725A (en) * 1980-04-03 1984-11-13 E. R. Squibb & Sons, Inc. S-Acylation products of mercaptoacyl amino acids and carboxyl group containing diuretics
RU2455287C1 (ru) * 2011-03-22 2012-07-10 Учреждение Российской академии наук Институт высокомолекулярных соединений РАН Способ получения (2s,4s)-3-(3-ацетилтиопропионил)-2-алкил(арил)-6-оксогексагидропиримидин-4-карбоновых кислот

Also Published As

Publication number Publication date
HU175671B (hu) 1980-09-28
BE861454A (fr) 1978-06-02
SU786895A3 (ru) 1980-12-07
SU795470A3 (ru) 1981-01-07
ZA777062B (en) 1979-02-28

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