CS199615B2 - Process for preparing derivatives of alkaloids - Google Patents

Process for preparing derivatives of alkaloids Download PDF

Info

Publication number
CS199615B2
CS199615B2 CS7699A CS9976A CS199615B2 CS 199615 B2 CS199615 B2 CS 199615B2 CS 7699 A CS7699 A CS 7699A CS 9976 A CS9976 A CS 9976A CS 199615 B2 CS199615 B2 CS 199615B2
Authority
CS
Czechoslovakia
Prior art keywords
group
alk
carbon atoms
formula
compound
Prior art date
Application number
CS7699A
Other languages
Czech (cs)
English (en)
Inventor
George J Cullinan
Koert Gerzon
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS199615B2 publication Critical patent/CS199615B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CS7699A 1975-01-09 1976-01-07 Process for preparing derivatives of alkaloids CS199615B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53968175A 1975-01-09 1975-01-09

Publications (1)

Publication Number Publication Date
CS199615B2 true CS199615B2 (en) 1980-07-31

Family

ID=24152219

Family Applications (1)

Application Number Title Priority Date Filing Date
CS7699A CS199615B2 (en) 1975-01-09 1976-01-07 Process for preparing derivatives of alkaloids

Country Status (13)

Country Link
JP (1) JPS5195100A (US20050065096A1-20050324-C00069.png)
BE (1) BE837390A (US20050065096A1-20050324-C00069.png)
CA (1) CA1067073A (US20050065096A1-20050324-C00069.png)
CH (1) CH624962A5 (US20050065096A1-20050324-C00069.png)
CS (1) CS199615B2 (US20050065096A1-20050324-C00069.png)
DE (1) DE2558027A1 (US20050065096A1-20050324-C00069.png)
FR (1) FR2297043A1 (US20050065096A1-20050324-C00069.png)
GB (1) GB1538921A (US20050065096A1-20050324-C00069.png)
HU (1) HU176226B (US20050065096A1-20050324-C00069.png)
IE (1) IE42385B1 (US20050065096A1-20050324-C00069.png)
IL (1) IL48685A (US20050065096A1-20050324-C00069.png)
NL (1) NL7515253A (US20050065096A1-20050324-C00069.png)
PH (1) PH17563A (US20050065096A1-20050324-C00069.png)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR69783B (US20050065096A1-20050324-C00069.png) * 1976-09-08 1982-07-07 Lilly Co Eli
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
GR68940B (US20050065096A1-20050324-C00069.png) * 1977-01-19 1982-03-29 Lilly Co Eli
US4191688A (en) 1977-08-08 1980-03-04 Eli Lilly And Company Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine
US4195022A (en) 1978-03-27 1980-03-25 Eli Lilly And Company 4-Desacetoxy-4α-hydroxyvinblastine and related compounds
US4166810A (en) * 1978-04-20 1979-09-04 Eli Lilly And Company Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
AR225153A1 (es) * 1978-10-10 1982-02-26 Lilly Co Eli Un procedimiento para la preparacion de sulfato de vindesina
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
LU83822A1 (fr) * 1981-12-08 1983-09-01 Omnichem Sa Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina

Also Published As

Publication number Publication date
BE837390A (fr) 1976-07-08
IL48685A0 (en) 1976-02-29
FR2297043B1 (US20050065096A1-20050324-C00069.png) 1978-08-11
HU176226B (en) 1981-01-28
CA1067073A (en) 1979-11-27
IL48685A (en) 1980-03-31
CH624962A5 (en) 1981-08-31
NL7515253A (nl) 1976-07-13
DE2558027A1 (de) 1976-07-15
IE42385B1 (en) 1980-07-30
FR2297043A1 (fr) 1976-08-06
GB1538921A (en) 1979-01-24
PH17563A (en) 1984-10-01
JPS5195100A (US20050065096A1-20050324-C00069.png) 1976-08-20
IE42385L (en) 1976-07-09

Similar Documents

Publication Publication Date Title
DK141511B (da) Analogifremgangsmåde til fremstilling af derivater af vindblastin, leurosidin eller leurocristin.
EP0005051B1 (en) 4-desacetyl vlb c-3 carboxhydrazides, their preparation and formulations containing them
CS199615B2 (en) Process for preparing derivatives of alkaloids
US6403636B1 (en) Xanthone compounds, their preparation and use as medicament
US3944554A (en) 4-Desacetoxy-3-hydroxyvinblastine
Crow et al. Alkaloids of the Australian Apocynaceae: Kopsia longiflora Merr. III. preliminary Degradation of the Alkaloids
DK161833B (da) Analogifremgangsmaade til fremstilling af n-(vinblastinoyl-23)-derivater af aminosyrer eller farmaceutisk acceptable syreadditionssalte deraf
DE2753791C2 (US20050065096A1-20050324-C00069.png)
HU182952B (en) Process for producing 1-formyl-indol-dihydroindol derivatives
JPS624398B2 (US20050065096A1-20050324-C00069.png)
US4189432A (en) N-formyl and N-desmethyl leurosine derivatives
EP0001920B1 (en) Vincaleukoblastine derivatives, a process for their preparation, pharmaceutical formulations containing them and the derivatives for use as antimitotic agents
AT345996B (de) Verfahren zur herstellung neuer amidderivate von vinblastin, leurosidin und leurocristin und ihrer saeureadditionssalze
KR790000810B1 (ko) 빈브라스틴 유도체의 제조방법
JPS6277372A (ja) ジロリン、その製造法およびそれを含有する薬学的組成物
Sako Syntheses of Pyridazine Derivatives. IV. Halogenopyridazine 1-Oxides
PL94203B1 (US20050065096A1-20050324-C00069.png)
IE47489B1 (en) 4-desacetoxy-4a-hydroxyindole-dihydroindoles,pharmaceutical formulations containing them and their use as antimitotic agents
HU179080B (en) Process for producing new 1,4-dithiepino-square bracket-2,3-c-square bracket closed-pyrrole derivatives
EP0205169A2 (en) Bis-indole derivatives, process for preparing same and pharmaceutical compositions containing them
PL90467B1 (US20050065096A1-20050324-C00069.png)