CS188414B1 - New d-6-alkyl-8-cyanmethyl ergolines,their salts and method of producing - Google Patents

New d-6-alkyl-8-cyanmethyl ergolines,their salts and method of producing

Info

Publication number
CS188414B1
CS188414B1 CS758472A CS847275A CS188414B1 CS 188414 B1 CS188414 B1 CS 188414B1 CS 758472 A CS758472 A CS 758472A CS 847275 A CS847275 A CS 847275A CS 188414 B1 CS188414 B1 CS 188414B1
Authority
CS
Czechoslovakia
Prior art keywords
cyanmethyl
ergolines
salts
alkyl
producing
Prior art date
Application number
CS758472A
Other languages
Czech (cs)
English (en)
Inventor
Antonin Cerny
Miroslav Semonsky
Rudolf Kotva
Karel Rezabek
Marie Auskova
Miroslav Seda
Original Assignee
Antonin Cerny
Miroslav Semonsky
Rudolf Kotva
Karel Rezabek
Marie Auskova
Miroslav Seda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antonin Cerny, Miroslav Semonsky, Rudolf Kotva, Karel Rezabek, Marie Auskova, Miroslav Seda filed Critical Antonin Cerny
Priority to CS758472A priority Critical patent/CS188414B1/cs
Priority to AU20377/76A priority patent/AU502928B2/en
Priority to AT881776A priority patent/AT356293B/de
Priority to FI763442A priority patent/FI61189C/fi
Priority to CH1514676A priority patent/CH622259A5/de
Priority to SE7613673A priority patent/SE419986B/xx
Priority to GB51352/76A priority patent/GB1505800A/en
Priority to DK553376AA priority patent/DK141874B/da
Priority to DE19762656093 priority patent/DE2656093A1/de
Priority to CA267,668A priority patent/CA1069502A/en
Priority to BE173188A priority patent/BE849318A/xx
Priority to JP14832576A priority patent/JPS5285195A/ja
Priority to FR7637531A priority patent/FR2334360A1/fr
Priority to US05/749,995 priority patent/US4321380A/en
Priority to NL7613843A priority patent/NL7613843A/xx
Publication of CS188414B1 publication Critical patent/CS188414B1/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CS758472A 1975-12-12 1975-12-12 New d-6-alkyl-8-cyanmethyl ergolines,their salts and method of producing CS188414B1 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
CS758472A CS188414B1 (en) 1975-12-12 1975-12-12 New d-6-alkyl-8-cyanmethyl ergolines,their salts and method of producing
AU20377/76A AU502928B2 (en) 1975-12-12 1976-09-08 8-cyanoethyl ergolines
AT881776A AT356293B (de) 1975-12-12 1976-11-29 Verfahren zur herstellung von neuen d-6-alkyl-8 -zyanmethylergolinen-i und deren salzen
FI763442A FI61189C (fi) 1975-12-12 1976-11-30 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara d-6-alkyl-8-cyanmetylergoliner-i och deras salt
CH1514676A CH622259A5 (US20110009641A1-20110113-C00256.png) 1975-12-12 1976-12-01
SE7613673A SE419986B (sv) 1975-12-12 1976-12-06 Analogiforfarande for framstellning av d-6-alkyl-8-cyanmetylergoliner-i
GB51352/76A GB1505800A (en) 1975-12-12 1976-12-09 D-6-alkyl-8-cyanomethylergolines their salts and methods of producing same
DK553376AA DK141874B (da) 1975-12-12 1976-12-09 Analogifremgangsmåde til fremstilling af D-6-alkyl-8-cyanmethylergolin-1'er eller farmaceutisk acceptable salte deraf.
DE19762656093 DE2656093A1 (de) 1975-12-12 1976-12-10 Neue d-6-alkyl-8-cyanomethylergolin-i-derivate, deren salze, verfahren zu ihrer herstellung und pharmazeutische mittel
CA267,668A CA1069502A (en) 1975-12-12 1976-12-10 D-6-alkyl-8-cyanomethylergolines, their salts and methods of producing them
BE173188A BE849318A (fr) 1975-12-12 1976-12-10 Procede de preparation de nouvelles d-6-alcoyle-8-cyanaogene-methyl-ergolines-i et de leurs sels et produits obtenues
JP14832576A JPS5285195A (en) 1975-12-12 1976-12-11 Dd66alkyll88cyanomethyl ergoline salts thereof and process for preparing same
FR7637531A FR2334360A1 (fr) 1975-12-12 1976-12-13 Procede de preparation des nouvelles d-6-alcoyle-8-cyanogene-methyl-ergolines- i et de leurs sels et produits obtenus par ce procede
US05/749,995 US4321380A (en) 1975-12-12 1976-12-13 Alkyl cyanomethyl ergoline-I derivatives and salts thereof, and methods for their preparation
NL7613843A NL7613843A (nl) 1975-12-12 1976-12-13 Derivaten van ergoline-i met prolactine remmende en gonadotropine stimulerende werking.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS758472A CS188414B1 (en) 1975-12-12 1975-12-12 New d-6-alkyl-8-cyanmethyl ergolines,their salts and method of producing

Publications (1)

Publication Number Publication Date
CS188414B1 true CS188414B1 (en) 1979-03-30

Family

ID=5435273

Family Applications (1)

Application Number Title Priority Date Filing Date
CS758472A CS188414B1 (en) 1975-12-12 1975-12-12 New d-6-alkyl-8-cyanmethyl ergolines,their salts and method of producing

Country Status (15)

Country Link
US (1) US4321380A (US20110009641A1-20110113-C00256.png)
JP (1) JPS5285195A (US20110009641A1-20110113-C00256.png)
AT (1) AT356293B (US20110009641A1-20110113-C00256.png)
AU (1) AU502928B2 (US20110009641A1-20110113-C00256.png)
BE (1) BE849318A (US20110009641A1-20110113-C00256.png)
CA (1) CA1069502A (US20110009641A1-20110113-C00256.png)
CH (1) CH622259A5 (US20110009641A1-20110113-C00256.png)
CS (1) CS188414B1 (US20110009641A1-20110113-C00256.png)
DE (1) DE2656093A1 (US20110009641A1-20110113-C00256.png)
DK (1) DK141874B (US20110009641A1-20110113-C00256.png)
FI (1) FI61189C (US20110009641A1-20110113-C00256.png)
FR (1) FR2334360A1 (US20110009641A1-20110113-C00256.png)
GB (1) GB1505800A (US20110009641A1-20110113-C00256.png)
NL (1) NL7613843A (US20110009641A1-20110113-C00256.png)
SE (1) SE419986B (US20110009641A1-20110113-C00256.png)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3913756A1 (de) * 1989-04-21 1990-10-25 Schering Ag 8(beta)-substituierte ergoline, verfahren zu ihrer herstellung und ihre verwendung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE712054A (US20110009641A1-20110113-C00256.png) * 1967-03-16 1968-07-15
US3920664A (en) * 1972-07-21 1975-11-18 Lilly Co Eli D-2-halo-6-alkyl-8-substituted ergolines and related compounds
US3880856A (en) * 1973-06-29 1975-04-29 Lilly Co Eli Ergoline dimers
CS171480B1 (US20110009641A1-20110113-C00256.png) * 1974-03-19 1976-10-29
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
US3992385A (en) * 1975-01-20 1976-11-16 Eli Lilly And Company 2,3-Dihydroergolines

Also Published As

Publication number Publication date
FI763442A (US20110009641A1-20110113-C00256.png) 1977-06-13
FI61189B (fi) 1982-02-26
BE849318A (fr) 1977-04-01
DK553376A (US20110009641A1-20110113-C00256.png) 1977-06-13
CH622259A5 (US20110009641A1-20110113-C00256.png) 1981-03-31
AT356293B (de) 1980-04-25
JPS5285195A (en) 1977-07-15
SE419986B (sv) 1981-09-07
AU502928B2 (en) 1979-08-16
AU2037776A (en) 1978-06-15
SE7613673L (sv) 1977-06-13
FR2334360A1 (fr) 1977-07-08
DK141874C (US20110009641A1-20110113-C00256.png) 1980-12-15
NL7613843A (nl) 1977-06-14
DE2656093A1 (de) 1977-06-23
GB1505800A (en) 1978-03-30
FR2334360B1 (US20110009641A1-20110113-C00256.png) 1980-03-07
US4321380A (en) 1982-03-23
FI61189C (fi) 1982-06-10
ATA881776A (de) 1979-09-15
CA1069502A (en) 1980-01-08
DK141874B (da) 1980-07-07

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