CS179980B2 - Method of production of 2-amino-4,5-dihydro-pyridine 3,5-dicarboxylic acid esters - Google Patents

Method of production of 2-amino-4,5-dihydro-pyridine 3,5-dicarboxylic acid esters

Info

Publication number
CS179980B2
CS179980B2 CS7300001590A CS159073A CS179980B2 CS 179980 B2 CS179980 B2 CS 179980B2 CS 7300001590 A CS7300001590 A CS 7300001590A CS 159073 A CS159073 A CS 159073A CS 179980 B2 CS179980 B2 CS 179980B2
Authority
CS
Czechoslovakia
Prior art keywords
dihydro
pyridine
amino
production
dicarboxylic acid
Prior art date
Application number
CS7300001590A
Other languages
Czech (cs)
English (en)
Inventor
Horst Mayer
Friedrich Bossert
Wulf Vater
Kurt Stoepel
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2210650A external-priority patent/DE2210650C3/de
Priority claimed from DE19722260860 external-priority patent/DE2260860A1/de
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of CS179980B2 publication Critical patent/CS179980B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyridine Compounds (AREA)
CS7300001590A 1972-03-06 1973-03-06 Method of production of 2-amino-4,5-dihydro-pyridine 3,5-dicarboxylic acid esters CS179980B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2210650A DE2210650C3 (de) 1972-03-06 1972-03-06 2-Amino-6-alkoxy-4,5-dihydropyridin-3,5-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
DE19722260860 DE2260860A1 (de) 1972-12-13 1972-12-13 Verfahren zur herstellung von neuen 2-amino-6-alkylmercapto-4,5-dihydropyridinen sowie ihre verwendung als antihypertensiva

Publications (1)

Publication Number Publication Date
CS179980B2 true CS179980B2 (en) 1977-12-30

Family

ID=25762843

Family Applications (1)

Application Number Title Priority Date Filing Date
CS7300001590A CS179980B2 (en) 1972-03-06 1973-03-06 Method of production of 2-amino-4,5-dihydro-pyridine 3,5-dicarboxylic acid esters

Country Status (16)

Country Link
US (1) US3876646A (no)
JP (1) JPS5626658B2 (no)
AT (1) AT325614B (no)
CA (1) CA985685A (no)
CH (1) CH580591A5 (no)
CS (1) CS179980B2 (no)
DD (1) DD106832A5 (no)
DK (1) DK135714C (no)
ES (1) ES412320A1 (no)
FR (1) FR2183673B1 (no)
GB (1) GB1374551A (no)
HU (1) HU167088B (no)
IE (1) IE37367B1 (no)
IL (1) IL41666A (no)
NL (1) NL7303134A (no)
SE (1) SE384206B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3951993A (en) * 1972-03-06 1976-04-20 Bayer Aktiengesellschaft 2-Amino-4,5-dihydropyridine derivatives and process for their preparation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern
DE2013431C3 (de) * 1970-03-20 1979-12-20 Bayer Ag, 5090 Leverkusen 4-Azidophenyl-l,4-dihydropyridin-3,5-dicarbonsäureester
DE1963186C3 (de) * 1969-12-17 1979-02-15 Bayer Ag, 5090 Leverkusen Schwefelhaltige 1,4-Dihydropyridin-33-dicarbonsäureester
ZA7152B (en) * 1970-01-24 1971-10-27 Bayer Ag New pharmaceutically active 1,4-dihydropyridines
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2117572C3 (de) * 1971-04-10 1980-03-20 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin ^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
JPS4899180A (no) 1973-12-15
FR2183673B1 (no) 1976-12-03
GB1374551A (en) 1974-11-20
AT325614B (de) 1975-10-27
CA985685A (en) 1976-03-16
DD106832A5 (no) 1974-07-05
ES412320A1 (es) 1976-04-16
ATA196973A (de) 1975-01-15
JPS5626658B2 (no) 1981-06-19
US3876646A (en) 1975-04-08
IE37367L (en) 1973-09-06
IE37367B1 (en) 1977-07-06
IL41666A0 (en) 1973-05-31
SE384206B (sv) 1976-04-26
CH580591A5 (no) 1976-10-15
DK135714C (da) 1977-11-14
IL41666A (en) 1976-02-29
FR2183673A1 (no) 1973-12-21
DK135714B (da) 1977-06-13
HU167088B (no) 1975-08-28
NL7303134A (no) 1973-09-10

Similar Documents

Publication Publication Date Title
CS194234B2 (en) Method of production of the bis-/dihydrixypropylamides/ of the acid 5-hydroxypropionylamino-2,4,6-troiodisophtale
SE398876B (sv) Sett att framstella basiska 1,4-dihydropyridinkarbonsyraestrar
CS187390B2 (en) Method of producing novel derivatives of benzimidazol-2-carbamic acid
IT1062792B (it) Procedimento di produzione di acido lattico
NZ176623A (en) The production of 7 -amino3-cephem-3-ol-4-carboxylic acid deriuatives, their 1-oxides and the corresponding 2-cephemderivatives
ZA729106B (en) Process of the production of (+)-trans-chrysanthemic acid
CS173597B2 (en) Method of 6-aminopenicillic acid production
JPS55105688A (en) Manufacture of novel penicillanic acid derivative
JPS53111073A (en) Method of producing pyridinecarboxylyc acid
IE38531B1 (en) Process for the production of n-chloroformyl-carbonic acid amides
IL41815A0 (en) Process for the production of 2,5-dichloro-3-nitro-benzoic acid
CS180568B2 (en) Method for production of novel tuberculostatically active derivatives of alfa-aminoxycarbonylhydroxamic acids
CS181280B2 (en) Method of production of citric acid esters,citric acid or citric acid salts
CS182792B2 (en) Method of production of 2,6-diaminodihydropyridines
ZA739729B (en) Production of esters
CA947216A (en) Process for the production of 6-aminopenicillanic acid
CS179980B2 (en) Method of production of 2-amino-4,5-dihydro-pyridine 3,5-dicarboxylic acid esters
EG11414A (en) 5-phenylsulfinyl-2-benzimidazolyl-carbamic acid esters and process for their manufacture
CS175748B1 (en) Method of alfa-6-deoxytetracycline production
CS179425B2 (en) Method for production of h-tetrasole-l-acetic acid and esters thereof.
YU39649B (en) Process for producing 6-amino-penicillanic acid
CS191211B2 (en) Method of production of the 0,0-dimethyl-event. 0,0-diethyl-0-/2,2-dichlorvinyl/esters of the thionofosfor for acid
CS181278B2 (en) Method of producing cephalosporane acid derivatives
CS188334B1 (en) Method of producing esters of 6,7-dialkoxy-4-oxyquinoline-3-carboxylic acid
IL33776A0 (en) Process for the production of o,o-dimethyl-thionophosphoric acid(o-quinoxalyl-(2))ester