CR9171A - NEW COMPOUNDS - Google Patents

NEW COMPOUNDS

Info

Publication number
CR9171A
CR9171A CR9171A CR9171A CR9171A CR 9171 A CR9171 A CR 9171A CR 9171 A CR9171 A CR 9171A CR 9171 A CR9171 A CR 9171A CR 9171 A CR9171 A CR 9171A
Authority
CR
Costa Rica
Prior art keywords
new compounds
alkyl
ocf3
het
alkoxyalkyl
Prior art date
Application number
CR9171A
Other languages
Spanish (es)
Inventor
Vincent Fish Paul
Ryckmans Thomas
Stobie Alan
Wakenhut Florian
Alistair Whitlock Gavilan
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CR9171A publication Critical patent/CR9171A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un compuesto de formula ( I ) y sus derivados farmaceutica y/o veterinariamente aceptables, en la que R1, R2 y R20 son cada uno independientemente H, CI, BR, F, I, CF3, OCF3, ME o Et, R4 es het o cicloalquilo de c 3-7 opcionalmente substituido con alquilo de c1-4, alcoxi de c1-4, alcoxialquilo qu econtiene de 2 a 4 atomos de carbono, o S-(alquilo de c1-4) a es 0 o 1A compound of formula (I) and its pharmaceutically and / or veterinarily acceptable derivatives, wherein R1, R2 and R20 are each independently H, CI, BR, F, I, CF3, OCF3, ME or Et, R4 is het or C 3-7 cycloalkyl optionally substituted with C 1-4 alkyl, C 1-4 alkoxy, alkoxyalkyl having 2 to 4 carbon atoms, or S- (C 1-4 alkyl) a is 0 or 1

CR9171A 2004-11-23 2007-06-07 NEW COMPOUNDS CR9171A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0425766.3A GB0425766D0 (en) 2004-11-23 2004-11-23 Novel compounds

Publications (1)

Publication Number Publication Date
CR9171A true CR9171A (en) 2007-07-04

Family

ID=33548739

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9171A CR9171A (en) 2004-11-23 2007-06-07 NEW COMPOUNDS

Country Status (26)

Country Link
EP (1) EP1817281A1 (en)
JP (1) JP4233596B2 (en)
KR (1) KR100886294B1 (en)
CN (1) CN101065355A (en)
AP (1) AP2007004003A0 (en)
AR (1) AR052243A1 (en)
AU (1) AU2005308534A1 (en)
BR (1) BRPI0518486A2 (en)
CA (1) CA2589258A1 (en)
CR (1) CR9171A (en)
EA (1) EA011217B1 (en)
GB (1) GB0425766D0 (en)
GT (1) GT200500337A (en)
IL (1) IL183191A0 (en)
MA (1) MA29038B1 (en)
MX (1) MX2007006138A (en)
NL (2) NL1030485C2 (en)
NO (1) NO20072486L (en)
PA (1) PA8653501A1 (en)
PE (1) PE20061056A1 (en)
SV (1) SV2006002311A (en)
TN (1) TNSN07201A1 (en)
TW (1) TWI300776B (en)
UY (1) UY29224A1 (en)
WO (1) WO2006056884A1 (en)
ZA (1) ZA200703910B (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH628885A5 (en) * 1978-01-01 1982-03-31 Anphar Sa Piperidine derivative
GB0314054D0 (en) * 2003-06-17 2003-07-23 Pfizer Ltd Amide derivatives as selective serotonin re-uptake inhibitors
ES2305776T3 (en) * 2003-06-17 2008-11-01 Pfizer Inc. DERIVATIVES OF N-PIRROLIDIN-3-IL-AMIDA AS INHIBITORS OF THE RE-CAPTURE OF SEROTONINE AND NORADRENALINE.

Also Published As

Publication number Publication date
TW200626543A (en) 2006-08-01
MA29038B1 (en) 2007-11-01
TWI300776B (en) 2008-09-11
BRPI0518486A2 (en) 2008-11-18
GB0425766D0 (en) 2004-12-22
EA011217B1 (en) 2009-02-27
IL183191A0 (en) 2007-08-19
ZA200703910B (en) 2008-09-25
GT200500337A (en) 2006-06-13
UY29224A1 (en) 2006-06-30
PA8653501A1 (en) 2006-06-02
TNSN07201A1 (en) 2008-11-21
CA2589258A1 (en) 2006-06-01
NL1032760C2 (en) 2007-04-17
MX2007006138A (en) 2007-07-19
PE20061056A1 (en) 2006-11-08
NL1030485A1 (en) 2006-05-24
KR20070086599A (en) 2007-08-27
NL1030485C2 (en) 2006-11-07
JP4233596B2 (en) 2009-03-04
SV2006002311A (en) 2006-09-14
NO20072486L (en) 2007-06-20
WO2006056884A1 (en) 2006-06-01
AU2005308534A1 (en) 2006-06-01
AR052243A1 (en) 2007-03-07
AP2007004003A0 (en) 2007-06-30
KR100886294B1 (en) 2009-03-04
CN101065355A (en) 2007-10-31
JP2008520646A (en) 2008-06-19
EP1817281A1 (en) 2007-08-15
EA200700920A1 (en) 2007-12-28
NL1032760A1 (en) 2006-12-13

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)