CR11057A - Nuevos compuestos heterociclicos nitrogenados, su preparacion y su utilizacion como medicamentos antibacterianos - Google Patents

Nuevos compuestos heterociclicos nitrogenados, su preparacion y su utilizacion como medicamentos antibacterianos

Info

Publication number
CR11057A
CR11057A CR11057A CR11057A CR11057A CR 11057 A CR11057 A CR 11057A CR 11057 A CR11057 A CR 11057A CR 11057 A CR11057 A CR 11057A CR 11057 A CR11057 A CR 11057A
Authority
CR
Costa Rica
Prior art keywords
preparation
new nitrogen
antibacterial medicines
compounds
heterociclic compounds
Prior art date
Application number
CR11057A
Other languages
English (en)
Inventor
Lampilas Maxime
Alun Rowlands David
Kebsi Adel
Ledoussal Benoit
Pierres Camille
Original Assignee
Novexel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novexel filed Critical Novexel
Publication of CR11057A publication Critical patent/CR11057A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/529—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La invencion trata de compuestos heterociclicos nitrogenados, su preparacion y su utilizacion como medicamentos antibacterianos, los compuestos de formula general (I).
CR11057A 2007-04-12 2009-10-09 Nuevos compuestos heterociclicos nitrogenados, su preparacion y su utilizacion como medicamentos antibacterianos CR11057A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0702663A FR2914923B1 (fr) 2007-04-12 2007-04-12 Nouveaux composes heterocycliques azotes,leur preparation et leur utilisation comme medicaments antibacteriens.

Publications (1)

Publication Number Publication Date
CR11057A true CR11057A (es) 2010-04-12

Family

ID=38704839

Family Applications (1)

Application Number Title Priority Date Filing Date
CR11057A CR11057A (es) 2007-04-12 2009-10-09 Nuevos compuestos heterociclicos nitrogenados, su preparacion y su utilizacion como medicamentos antibacterianos

Country Status (30)

Country Link
US (1) US8063219B2 (es)
EP (1) EP2146994B1 (es)
JP (1) JP2010523630A (es)
KR (1) KR20090130126A (es)
CN (1) CN101687870B (es)
AR (1) AR066023A1 (es)
AU (1) AU2008252799B2 (es)
BR (1) BRPI0809593A2 (es)
CA (1) CA2683350A1 (es)
CL (1) CL2008001048A1 (es)
CO (1) CO6220973A2 (es)
CR (1) CR11057A (es)
CU (1) CU23854B1 (es)
EC (1) ECSP099682A (es)
FR (1) FR2914923B1 (es)
GT (1) GT200900266A (es)
HN (1) HN2009002099A (es)
IL (1) IL201252A (es)
MX (1) MX2009010837A (es)
MY (1) MY152839A (es)
NI (1) NI200900181A (es)
NZ (1) NZ580238A (es)
PA (1) PA8776401A1 (es)
PE (1) PE20090235A1 (es)
RU (1) RU2465276C2 (es)
SV (1) SV2009003391A (es)
TW (1) TWI403323B (es)
UY (1) UY31016A1 (es)
WO (1) WO2008142285A1 (es)
ZA (1) ZA200906784B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE50204789D1 (de) * 2001-05-10 2005-12-08 Solvay Pharm Gmbh Neue 1-amidomethylcarbonyl-piperidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2936798B1 (fr) * 2008-10-03 2012-09-28 Novexel Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens.
FR2937034B1 (fr) * 2008-10-10 2012-11-23 Novexel Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens
US8796257B2 (en) 2011-12-02 2014-08-05 Naeja Pharmaceutical Inc. Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors
US9505761B2 (en) 2011-12-02 2016-11-29 Fedora Pharmaceuticals Inc. Bicyclic compounds and their use as antibacterial agents and beta-lactamase inhibitors
AR090539A1 (es) 2012-04-02 2014-11-19 Astrazeneca Ab COMPUESTOS INHIBIDORES DE b LACTAMASA
UA111925C2 (uk) 2012-12-11 2016-06-24 Федора Фармасьютікалз Інк. БІЦИКЛІЧНІ СПОЛУКИ ТА ЇХ ВИКОРИСТАННЯ ЯК АНТИБАКТЕРІАЛЬНИХ АГЕНТІВ ТА ІНГІБІТОРІВ β-ЛАКТАМАЗИ
WO2016081452A1 (en) 2014-11-17 2016-05-26 Entasis Therapeutics Limited Combination therapy for treatment of resistant bacterial infections
WO2018053215A1 (en) 2016-09-16 2018-03-22 Entasis Therapeutics Limited Beta-lactamase inhibitor compounds
SG11201909443YA (en) 2017-05-08 2019-11-28 Entasis Therapeutics Inc Compounds and methods for treating bacterial infections

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2812635B1 (fr) * 2000-08-01 2002-10-11 Aventis Pharma Sa Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens
FR2825705B1 (fr) * 2001-06-08 2005-05-20 Aventis Pharma Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens
US7439253B2 (en) * 2002-12-06 2008-10-21 Novexel Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
FR2848210B1 (fr) * 2002-12-06 2007-10-19 Aventis Pharma Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens et inhibiteurs de beta-lactamases
RU2228934C1 (ru) * 2003-05-20 2004-05-20 ООО "Исследовательский институт химического разнообразия" Замещенные 3,7-диазобицикло[3.3.1]нонаны, фокусированная библиотека и комбинаторная библиотека

Also Published As

Publication number Publication date
FR2914923A1 (fr) 2008-10-17
NZ580238A (en) 2012-03-30
US20100137355A1 (en) 2010-06-03
AU2008252799B2 (en) 2013-08-15
NI200900181A (es) 2011-07-25
TWI403323B (zh) 2013-08-01
AU2008252799A1 (en) 2008-11-27
MY152839A (en) 2014-11-28
WO2008142285A1 (fr) 2008-11-27
US8063219B2 (en) 2011-11-22
TW200904445A (en) 2009-02-01
MX2009010837A (es) 2010-01-15
ZA200906784B (en) 2011-03-30
FR2914923B1 (fr) 2013-06-14
RU2009137255A (ru) 2011-05-20
UY31016A1 (es) 2008-11-28
RU2465276C2 (ru) 2012-10-27
CA2683350A1 (fr) 2008-11-27
CN101687870B (zh) 2013-06-19
AR066023A1 (es) 2009-07-15
EP2146994A1 (fr) 2010-01-27
IL201252A (en) 2014-08-31
HN2009002099A (es) 2012-01-05
CU23854B1 (es) 2012-11-15
CL2008001048A1 (es) 2008-08-08
KR20090130126A (ko) 2009-12-17
IL201252A0 (en) 2010-05-31
GT200900266A (es) 2011-09-23
PA8776401A1 (es) 2008-11-19
CO6220973A2 (es) 2010-11-19
CN101687870A (zh) 2010-03-31
EP2146994B1 (fr) 2015-07-01
PE20090235A1 (es) 2009-03-12
CU20090173A7 (es) 2011-10-14
BRPI0809593A2 (pt) 2014-09-30
ECSP099682A (es) 2009-12-28
SV2009003391A (es) 2010-07-02
JP2010523630A (ja) 2010-07-15

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