CO6351796A2 - TOXIN GENES AND METHODS FOR USE - Google Patents

TOXIN GENES AND METHODS FOR USE

Info

Publication number
CO6351796A2
CO6351796A2 CO10157545A CO10157545A CO6351796A2 CO 6351796 A2 CO6351796 A2 CO 6351796A2 CO 10157545 A CO10157545 A CO 10157545A CO 10157545 A CO10157545 A CO 10157545A CO 6351796 A2 CO6351796 A2 CO 6351796A2
Authority
CO
Colombia
Prior art keywords
plants
compositions
amino acid
bacteria
methods
Prior art date
Application number
CO10157545A
Other languages
Spanish (es)
Inventor
Shruti Agarwal
Chris Campbell
Daniel Tomso
Kimberly Sampson
Bryan Mcnulty
Original Assignee
Athenix Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41258971&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6351796(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Athenix Corp filed Critical Athenix Corp
Publication of CO6351796A2 publication Critical patent/CO6351796A2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/18Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1278Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Bacillus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pest Control & Pesticides (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Insects & Arthropods (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pretreatment Of Seeds And Plants (AREA)

Abstract

Se proporcionan composiciones y métodos para conferir actividad pesticida contra bacterias, plantas, células vegetales, tejidos y semillas. Se proporcionan composiciones que comprenden una secuencia codificadora para un polipéptido de delta-endotoxina. Las secuencias codificadoras pueden utilizarse en constructos de ADN o cassettes de expresión para transformación y expresión en plantas y bacterias. Las composiciones también comprenden bacterias, plantas, células vegetales, tejidos y semillas transformados. En particular, se proporcionan moléculas aisladas de ácido nucleico de delta-endotoxina. Adicionalmente, están comprendidas secuencias de aminoácidos que corresponden a los polinucleótidos y anticuerpos que se unen específicamente a dichas secuencias de aminoácidos. En particular, la presente invención prevé moléculas de ácido nucleico aisladas que comprenden una secuencia de nucleótidos que codifica la secuencia de aminoácidos que se muestra en cualquiera de SEQ ID NO:61-121 y 133-141, o una secuencia de nucleótidos que se indica en SEQ ID NO:1-60,124-132 y 142-283, así como también variantes y fragmentos de las mismas.Compositions and methods for conferring pesticidal activity against bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a delta-endotoxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. The compositions also comprise bacteria, plants, plant cells, tissues and transformed seeds. In particular, isolated delta-endotoxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to polynucleotides and antibodies that specifically bind said amino acid sequences are included. In particular, the present invention provides isolated nucleic acid molecules comprising a nucleotide sequence encoding the amino acid sequence shown in any of SEQ ID NO: 61-121 and 133-141, or a nucleotide sequence indicated in SEQ ID NO: 1-60,124-132 and 142-283, as well as variants and fragments thereof.

CO10157545A 2008-06-25 2010-12-15 TOXIN GENES AND METHODS FOR USE CO6351796A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7571908P 2008-06-25 2008-06-25
US15813709P 2009-03-06 2009-03-06

Publications (1)

Publication Number Publication Date
CO6351796A2 true CO6351796A2 (en) 2011-12-20

Family

ID=41258971

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10157545A CO6351796A2 (en) 2008-06-25 2010-12-15 TOXIN GENES AND METHODS FOR USE

Country Status (19)

Country Link
US (5) US8461421B2 (en)
EP (4) EP3470419B1 (en)
JP (1) JP2011526150A (en)
CN (2) CN105002189A (en)
AR (1) AR072316A1 (en)
AU (1) AU2009262153B2 (en)
BR (2) BRPI0914780B8 (en)
CA (2) CA3008307C (en)
CL (1) CL2010001436A1 (en)
CO (1) CO6351796A2 (en)
EA (2) EA030439B1 (en)
ES (1) ES2911327T3 (en)
MX (2) MX2010013910A (en)
NZ (2) NZ589991A (en)
PE (2) PE20110599A1 (en)
PH (1) PH12014500606A1 (en)
UA (1) UA121093C2 (en)
WO (1) WO2009158470A2 (en)
ZA (1) ZA201009045B (en)

Families Citing this family (118)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2406278A2 (en) * 2009-03-11 2012-01-18 Athenix Corp. Axmi-001, axmi-002, axmi-030, axmi-035, and axmi-045: insecticidal proteins from bacillus thuringiensis and methods for their use
WO2011009182A2 (en) * 2009-07-24 2011-01-27 Embrapa - Empresa Brasileira De Pesquisa Agropecuária Isolated nucleic acid molecule, genetic construct, vector, transgenic cell, method for producing a transgenic cell and plant, isolated and purified polypeptide, biodegradable pesticide composition, pest control method, method for producing transgenic strains resistant to insect pests
US10647993B2 (en) * 2009-07-24 2020-05-12 Empresa Brasileira de Pesquisa Agropecuaria—EMBRAPA Genetic construct expressing insecticidal toxin and the method of using thereof
US8609937B2 (en) * 2009-12-21 2013-12-17 Pioneer Hi Bred International Inc Bacillus thuringiensis gene with coleopteran activity
RS55986B1 (en) 2010-01-22 2017-09-29 Bayer Ip Gmbh Acaricides and/or insecticidal agent combinations
BR112012020921A2 (en) 2010-02-18 2015-09-08 Athenix Corp delta-endotoxin genes axmi218, axmi219, axmi220, axmi226, axmi227, axmi228, axmi229, axmi230 and axmi231 and methods for their use
US9234208B1 (en) * 2010-05-10 2016-01-12 Dow Agrosciences Llc DIG-13 insecticidal cry toxins
JP2012082186A (en) 2010-09-15 2012-04-26 Bayer Cropscience Ag Insecticidal arylpyrrolidines
US8865622B2 (en) * 2010-09-22 2014-10-21 Bayer Intellectual Property Gmbh Use of active ingredients for controlling nematodes in nematode-resistant crops
WO2012065944A1 (en) 2010-11-15 2012-05-24 Bayer Cropscience Ag N-aryl pyrazole(thio)carboxamides
EP2663452A4 (en) 2011-01-14 2014-07-09 Certainteed Gypsum Inc Composite building boards with thermoplastic coatings and cementitious precoated fibrous mats
WO2012135501A2 (en) * 2011-03-30 2012-10-04 Athenix Corp. Axmi232, axmi233, and axmi249 toxin genes and methods for their use
CA2838955C (en) 2011-06-16 2023-10-24 The Regents Of The University Of California Synthetic gene clusters
AU2012293636B2 (en) 2011-08-10 2015-12-03 Bayer Intellectual Property Gmbh Active compound combinations comprising specific tetramic acid derivatives
EA025208B1 (en) * 2011-08-19 2016-11-30 Синтетик Дженомикс, Инк. Integrated method for high-throughput identification of novel pesticidal compositions and uses thereof
CN102363632A (en) * 2011-11-09 2012-02-29 四川农业大学 A kind of insecticidal Bt protein Cry8Kb1, its coding gene and application
CN102517228B (en) * 2011-11-29 2014-02-19 四川农业大学 A strain of Bacillus thuringiensis ST7 and its anticancer gene and application
CN102408472B (en) * 2011-11-29 2013-04-10 四川农业大学 Bt (Bacillus Thuringiensis) protein Cry62Aa1 and coding gene as well as application thereof
CN102408474B (en) * 2011-12-07 2013-04-10 四川农业大学 Bt protein Cry69Aa1, and coding gene and application thereof
US9725735B2 (en) * 2012-03-08 2017-08-08 Athenix Corp. AXMI345 delta-endotoxin gene and methods for its use
TWI654180B (en) 2012-06-29 2019-03-21 美商艾佛艾姆希公司 Fungicidal heterocyclic carboxamide
WO2014036238A1 (en) * 2012-08-30 2014-03-06 Athenix Corp. Axmi-234 and axmi-235 toxin genes and methods for their use
EP2906703A2 (en) 2012-10-15 2015-08-19 Pioneer Hi-Bred International, Inc. Methods and compositions to enhance activity of cry endotoxins
US10968446B2 (en) 2012-11-01 2021-04-06 Massachusetts Institute Of Technology Directed evolution of synthetic gene cluster
EP2735231A1 (en) 2012-11-23 2014-05-28 Bayer CropScience AG Active compound combinations
BR112015012473A2 (en) 2012-11-30 2017-07-11 Bayer Cropscience Ag pesticide and fungicide binary mixtures
EP2925138A1 (en) 2012-11-30 2015-10-07 Bayer CropScience AG Ternary fungicidal and pesticidal mixtures
PL2925134T3 (en) 2012-11-30 2020-06-29 Bayer Cropscience Ag Ternary fungicidal mixtures
CN115960896A (en) 2013-03-14 2023-04-14 先锋国际良种公司 Compositions and methods for controlling insect pests
US10023877B2 (en) 2013-03-15 2018-07-17 Pioneer Hi-Bred International, Inc. PHI-4 polypeptides and methods for their use
AR097292A1 (en) * 2013-08-09 2016-03-02 Monsanto Technology Llc ACTIVE PESTICIDE TOXIN AGAINST COLEOPTER AND / OR HEMIPTER INSECTS
WO2015038262A2 (en) * 2013-08-09 2015-03-19 Athenix Corp. Axmi281 toxin gene and methods for its use
CA2920339C (en) 2013-08-16 2023-10-24 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
BR122020001770B1 (en) 2013-09-13 2022-11-29 Pioneer Hi-Bred International, Inc DNA CONSTRUCTION, METHOD FOR OBTAINING A TRANSGENIC PLANT, FUSION PROTEIN, METHOD FOR CONTROLLING AN INSECT PEST POPULATION, METHOD FOR INHIBITING THE GROWTH OR KILLING AN INSECT PEST
WO2015120270A1 (en) 2014-02-07 2015-08-13 Pioneer Hi Bred International, Inc. Insecticidal proteins and methods for their use
MX2016010187A (en) 2014-02-07 2017-07-11 Pioneer Hi Bred Int INSECTICIDED PROTEINS AND METHODS FOR USE.
WO2016000237A1 (en) 2014-07-03 2016-01-07 Pioneer Overseas Corporation Plants having enhanced tolerance to insect pests and related constructs and methods involving insect tolerance genes
US20170247719A1 (en) 2014-09-17 2017-08-31 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
EP3207144B1 (en) 2014-10-16 2019-05-01 Monsanto Technology LLC Lepidopteran-active cry1da1 amino acid sequence variant proteins
US10316329B2 (en) 2014-10-16 2019-06-11 Monsanto Technology Llc Proteins toxic or inhibitory to lepidopteran insects
US10487123B2 (en) 2014-10-16 2019-11-26 Monsanto Technology Llc Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
WO2016061206A1 (en) 2014-10-16 2016-04-21 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
PE20170895A1 (en) 2014-10-16 2017-07-12 Monsanto Technology Llc NOVEDOUS INSECTICIDE CHEMERIC PROTEINS TOXIC OR INHIBITOR OF LEPIDOPTER PESTS
RU2745322C2 (en) 2014-12-12 2021-03-23 Зингента Партисипейшнс Аг Compositions and methods for controlling plant pests
AU2015369927A1 (en) 2014-12-22 2017-07-06 AgBiome, Inc. Pesticidal genes and methods of use
EP3244727A4 (en) * 2015-01-15 2018-10-31 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
WO2016144688A1 (en) 2015-03-11 2016-09-15 Pioneer Hi Bred International Inc Insecticidal combinations of pip-72 and methods of use
US20160304898A1 (en) 2015-04-17 2016-10-20 AgBiome, Inc. Pesticidal Genes and Methods of Use
US10053707B2 (en) 2015-04-22 2018-08-21 AgBiome, Inc. Pesticidal genes and methods of use
RU2017144238A (en) 2015-05-19 2019-06-19 Пайонир Хай-Бред Интернэшнл, Инк. INSECTICIDAL PROTEINS AND METHODS OF THEIR APPLICATION
EP3303595A2 (en) * 2015-06-03 2018-04-11 Agbiome, Inc. Pesticidal genes and methods of use
US10647995B2 (en) 2015-06-16 2020-05-12 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
UA125336C2 (en) 2015-06-22 2022-02-23 Аґбайомі, Інк. PESTICIDE GENE AND METHOD OF ITS APPLICATION
EP3115458A1 (en) 2015-07-06 2017-01-11 Genective Method for gene optimization
CA2991776A1 (en) 2015-07-13 2017-01-19 Pivot Bio, Inc. Methods and compositions for improving plant traits
BR112018002535A2 (en) 2015-08-06 2018-09-25 Du Pont recombinant insecticidal polypeptide, recombinant polynucleotide, dna construct, transgenic plant or plant cell, composition, fusion protein, method for controlling a pest, method for inhibiting growth or for exterminating a pest or pest population and use of the polypeptide
WO2017030808A1 (en) * 2015-08-18 2017-02-23 Monsanto Technology Llc Novel insect inhibitory proteins
AU2016315655A1 (en) 2015-08-28 2018-02-01 E. I. Du Pont De Nemours And Company Ochrobactrum-mediated transformation of plants
US11479516B2 (en) 2015-10-05 2022-10-25 Massachusetts Institute Of Technology Nitrogen fixation using refactored NIF clusters
CN114470192A (en) * 2015-10-13 2022-05-13 优瑞科生物技术公司 Antibody agent specific for human CD19 and use thereof
ES2954940T3 (en) * 2015-10-14 2023-11-27 BASF Agricultural Solutions Seed US LLC Delta-endotoxin axmi554 gene and procedures for its use
RU2767209C2 (en) 2015-10-23 2022-03-16 Еурека Терапьютикс, Инк. Chimeric antibody/t-cell receptor structures and their applications
CA3002995A1 (en) 2015-12-18 2017-06-22 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
EP3394269A2 (en) 2015-12-22 2018-10-31 AgBiome, Inc. Pesticidal genes and methods of use
US11781151B2 (en) 2016-04-14 2023-10-10 Pioneer Hi-Bred International, Inc. Insecticidal CRY1B variants having improved activity spectrum and uses thereof
CA3021391A1 (en) 2016-04-19 2017-10-26 Pioneer Hi-Bred International, Inc. Insecticidal combinations of polypeptides having improved activity spectrum and uses thereof
EP3960863B1 (en) 2016-05-04 2024-11-13 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
WO2017218207A1 (en) 2016-06-16 2017-12-21 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
CA3026653A1 (en) 2016-06-24 2017-12-28 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
CA3026113A1 (en) 2016-07-01 2018-01-04 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
WO2018013333A1 (en) 2016-07-12 2018-01-18 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
CN110214189A (en) 2016-09-06 2019-09-06 农业生物群落股份有限公司 Killing gene and application method
CN116003539A (en) 2016-11-01 2023-04-25 先锋国际良种公司 Insecticidal proteins and methods of use thereof
CA3044404A1 (en) 2016-12-14 2018-06-21 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
WO2018118811A1 (en) 2016-12-22 2018-06-28 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
CN110799474B (en) 2017-01-12 2022-07-26 皮沃特生物公司 Methods and compositions for improving plant traits
WO2018140214A1 (en) 2017-01-24 2018-08-02 Pioneer Hi-Bred International, Inc. Nematicidal protein from pseudomonas
BR112019015582A2 (en) 2017-01-30 2020-03-10 AgBiome, Inc. PESTICIDAL GENES AND METHODS OF USE
US20190390219A1 (en) 2017-02-08 2019-12-26 Pioneer Hi-Bred International, Inc. Insecticidal combinations of plant derived insecticidal proteins and methods for their use
BR112019021380A2 (en) 2017-04-11 2020-05-05 Agbiome Inc pesticide genes and methods of use
AU2018258045B2 (en) 2017-04-26 2024-02-29 Eureka Therapeutics, Inc. Chimeric antibody/T-cell receptor constructs and uses thereof
UA126807C2 (en) 2017-05-11 2023-02-08 Піонір Хай-Бред Інтернешнл, Інк. INSECTICIDAL PROTEIN AND METHOD OF ITS APPLICATION
WO2018217333A1 (en) 2017-05-26 2018-11-29 Pioneer Hi-Bred International, Inc. Insecticidal polypeptides having improved activity spectrum and uses thereof
BR112020002279A2 (en) 2017-08-03 2020-07-28 AgBiome, Inc. pesticide genes and methods of use
WO2019074598A1 (en) 2017-10-13 2019-04-18 Pioneer Hi-Bred International, Inc. Virus-induced gene silencing technology for insect control in maize
KR20200087166A (en) 2017-10-25 2020-07-20 피벗 바이오, 인크. Gene targeting for nitrogen fixation targeting to improve plant properties
WO2019084059A2 (en) 2017-10-25 2019-05-02 Pivot Bio, Inc. Methods and compositions for improving engineered microbes that fix nitrogen
US10907173B2 (en) 2017-12-22 2021-02-02 AgBiome, Inc. Pesticidal genes and methods of use
EP3755797A1 (en) 2018-02-22 2020-12-30 Zymergen, Inc. Method for creating a genomic library enriched for bacillus and identification of novel cry toxins
AR114446A1 (en) 2018-03-02 2020-09-09 Zymergen Inc PLATFORM FOR THE DISCOVERY OF INSECTICIDE PROTEINS, AND INSECTICIDE PROTEINS DISCOVERED FROM THE SAME
US20210002657A1 (en) 2018-03-02 2021-01-07 Pioneer Hi-Bred International, Inc. Plant health assay
CA3092075A1 (en) 2018-03-14 2019-09-19 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
CN112020302B9 (en) 2018-03-14 2023-05-09 先锋国际良种公司 Insecticidal proteins from plants and methods of use thereof
WO2019204584A1 (en) 2018-04-20 2019-10-24 AgBiome, Inc. Pesticidal proteins and methods of use
CA3096516A1 (en) 2018-05-22 2019-11-28 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
CA3103977A1 (en) 2018-06-27 2020-01-02 Pivot Bio, Inc. Agricultural compositions comprising remodeled nitrogen fixing microbes
CN112739202A (en) 2018-07-11 2021-04-30 皮沃特生物股份有限公司 Temporally and spatially targeted dynamic nitrogen delivery by remodeling microbes
BR112021003797A2 (en) 2018-08-29 2021-05-25 Pioneer Hi-Bred International, Inc. insecticidal proteins and methods for their use
WO2020047704A1 (en) * 2018-09-03 2020-03-12 Syngenta Participations Ag Compositions and methods for controlling plant pests
WO2020190363A1 (en) 2019-03-19 2020-09-24 Massachusetts Institute Of Technology Control of nitrogen fixation in rhizobia that associate with cereals
WO2021076346A1 (en) 2019-10-18 2021-04-22 Pioneer Hi-Bred International, Inc. Maize event dp-202216-6 and dp-023211-2 stack
RU2744443C1 (en) * 2019-12-17 2021-03-09 Российская Федерация, от имени которой выступает Министерство здравохранения Российской Федерации Reagent-software complex for target analysis
CA3172637A1 (en) 2020-05-01 2021-11-04 Pivot Bio, Inc. Measurement of nitrogen fixation and incorporation
CA3186978A1 (en) 2020-07-14 2022-01-20 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
WO2022035649A1 (en) 2020-08-10 2022-02-17 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
US11780890B2 (en) 2020-11-24 2023-10-10 AgBiome, Inc. Pesticidal genes and methods of use
WO2022125639A1 (en) 2020-12-08 2022-06-16 Monsanto Technology Llc Modified plant-associated bacteria and methods of their use
MX2023007427A (en) 2020-12-21 2023-07-03 Monsanto Technology Llc Novel insect inhibitory proteins.
UY39585A (en) 2020-12-23 2022-07-29 Monsanto Technology Llc PROTEINS THAT EXHIBIT INSECT INHIBITOR ACTIVITY AGAINST PESTS OF AGRICULTURAL IMPORTANCE OF CROP PLANTS AND SEEDS
WO2022146874A1 (en) 2020-12-31 2022-07-07 Monsanto Technology Llc Novel insect inhibitory proteins
AR125794A1 (en) 2021-05-06 2023-08-16 Agbiome Inc PESTICIDE GENES AND METHODS OF USE
EP4381052A4 (en) 2021-07-08 2025-07-02 Monsanto Technology Llc NEW INSECT-REPELLENT PROTEINS
WO2023107943A1 (en) 2021-12-07 2023-06-15 AgBiome, Inc. Pesticidal genes and methods of use
WO2024044596A1 (en) 2022-08-23 2024-02-29 AgBiome, Inc. Pesticidal genes and methods of use
WO2024129674A1 (en) 2022-12-13 2024-06-20 AgBiome, Inc. Pesticidal genes and methods of use
AU2024245952A1 (en) * 2023-03-31 2025-10-09 Ctc - Centro De Tecnologia Canavieira S.A. Recombinant cry protein for controlling insect pests
WO2025178772A1 (en) 2024-02-23 2025-08-28 Genective Sa Insecticidal proteins compositions and methods of use
WO2025193453A1 (en) 2024-03-14 2025-09-18 Genective Sa Insecticidal proteins compositions and methods of use

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1506602A (en) 1922-05-17 1924-08-26 Nichols Henry Vehicle wheel
US4196265A (en) 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US5380831A (en) 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
DE3685968T2 (en) 1985-01-22 1993-07-01 Mycogen Corp CELLULAR ENCLOSURE OF BIOLOGICAL PESTICIDES.
US6028346A (en) * 1986-04-25 2000-02-22 Mitsubishi Denki Kabushiki Kaisha Isolated trench semiconductor device
US5039523A (en) 1988-10-27 1991-08-13 Mycogen Corporation Novel Bacillus thuringiensis isolate denoted B.t. PS81F, active against lepidopteran pests, and a gene encoding a lepidopteran-active toxin
US5240842A (en) 1989-07-11 1993-08-31 Biotechnology Research And Development Corporation Aerosol beam microinjector
AU642889B2 (en) 1989-07-11 1993-11-04 Biotechnology Research And Development Corporation Aerosol beam microinjector
CA2051562C (en) 1990-10-12 2003-12-02 Jewel M. Payne Bacillus thuringiensis isolates active against dipteran pests
UA48104C2 (en) * 1991-10-04 2002-08-15 Новартіс Аг Dna fragment including sequence that codes an insecticide protein with optimization for corn, dna fragment providing directed preferable for the stem core expression of the structural gene of the plant related to it, dna fragment providing specific for the pollen expression of related to it structural gene in the plant, recombinant dna molecule, method for obtaining a coding sequence of the insecticide protein optimized for corn, method of corn plants protection at least against one pest insect
TW261517B (en) 1991-11-29 1995-11-01 Mitsubishi Shozi Kk
CA2143296C (en) * 1992-08-27 2010-01-05 Bart Lambert New bacillus thuringiensis strains and their insecticidal proteins
US5743477A (en) 1992-08-27 1998-04-28 Dowelanco Insecticidal proteins and method for plant protection
EP0694062B1 (en) * 1993-04-09 2010-08-04 Bayer BioScience N.V. New bacillus thuringiensis strains and their insecticidal proteins
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5994526A (en) * 1996-06-21 1999-11-30 Plant Genetic Systems Gene expression in plants
US7129212B2 (en) * 1996-10-30 2006-10-31 Mycogen Corporation Polynucleotides, pesticidal proteins, and novel methods of using them
US6017534A (en) * 1996-11-20 2000-01-25 Ecogen, Inc. Hybrid Bacillus thuringiensis δ-endotoxins with novel broad-spectrum insecticidal activity
TR199901109T2 (en) * 1996-11-20 1999-10-21 Ecogen, Inc Broad spectrum delta-endotoxins.
US5942664A (en) * 1996-11-27 1999-08-24 Ecogen, Inc. Bacillus thuringiensis Cry1C compositions toxic to lepidopteran insects and methods for making Cry1C mutants
KR20010082543A (en) * 1998-05-01 2001-08-30 추후제출 Optimization of pest resistance genes using dna shuffling
US6468523B1 (en) 1998-11-02 2002-10-22 Monsanto Technology Llc Polypeptide compositions toxic to diabrotic insects, and methods of use
US6938976B2 (en) 1999-06-16 2005-09-06 Eastman Kodak Company Printer and method therefor adapted to sense data uniquely associated with a consumable loaded into the printer
BR0014516A (en) * 1999-09-15 2002-07-02 Monsanto Technology Llc Compositions and methods of using delta-endotoxin from active lepidopteran bacillus thuringiensis
CN1375009A (en) * 1999-09-17 2002-10-16 阿温提斯作物科学公司 Insect-resistant rice plants
BR0016030A (en) 1999-11-29 2002-07-30 Midwest Oilseeds Inc Methods and compositions for introducing molecules into cells
ATE421973T1 (en) * 1999-12-28 2009-02-15 Bayer Bioscience Nv INCECTICIDAL PROTEINS OF BACILLUS THURINGIENSIS
US20020038005A1 (en) * 2000-01-07 2002-03-28 Wojciechowska Jana Alexandrovna Novel delta-endotoxins and nucleic acid sequences coding therefor
WO2001087940A2 (en) * 2000-05-15 2001-11-22 Monsanto Technology Llc Polypeptide composionns toxic to anthonomus insects, and use thereof
FR2822157B1 (en) * 2001-03-19 2003-10-31 Aventis Cropscience Sa MODIFIED BACILLUS THURINGIENSIS INSECTICIDE TOXIN SENSITIVE TO PEPSIN
CA2478964A1 (en) 2002-03-11 2003-09-25 Athenix Corporation Integrated system for high throughput capture of genetic diversity
US7053266B2 (en) * 2002-03-27 2006-05-30 Council Of Scientfic And Industrial Research Chimeric cry1E δendotoxin and methods of controlling insects
US6927062B2 (en) * 2002-11-25 2005-08-09 Agdia, Inc. Controls and standards for assays and method for manufacture thereof
EP1947184B1 (en) * 2003-02-20 2011-03-30 Athenix Corporation Delta-endotoxin genes and methods for their use
US7351881B2 (en) * 2003-02-20 2008-04-01 Athenix Corporation AXMI-008, a delta-endotoxin gene and methods for its use
WO2005066202A2 (en) * 2003-12-22 2005-07-21 E.I. Du Pont De Nemours And Company Bacillus cry9 family members
CN1950395A (en) * 2004-03-02 2007-04-18 美国陶氏益农公司 Insecticidal toxin complex fusion proteins
US8143474B2 (en) * 2006-04-18 2012-03-27 Rutgers, The State University Of New Jersey Compositions and methods for increasing transgene expression in the plastids of higher plants
EP2032598B1 (en) * 2006-06-14 2012-10-17 Athenix Corporation Axmi-031, axmi-039, axmi-040 and axmi-049, a family of delta-endotoxin genes and methods for their use
EP2455393A3 (en) * 2006-06-15 2012-08-22 Athenix Corporation A family of pesticidal proteins and methods for their use
US7858849B2 (en) * 2006-12-08 2010-12-28 Pioneer Hi-Bred International, Inc. Bacillus thuringiensis crystal polypeptides, polynucleotides, and compositions thereof
US7772465B2 (en) 2007-06-26 2010-08-10 Pioneer Hi-Bred International, Inc. Bacillus thuringiensis gene with lepidopteran activity
AR081386A1 (en) * 2010-05-10 2012-08-29 Texas A & M Univ Sys COMPOSITIONS, ORGANISMS, SYSTEMS AND METHODS TO EXPRESS A GENETIC PRODUCT IN PLANTS

Also Published As

Publication number Publication date
JP2011526150A (en) 2011-10-06
BRPI0914780B8 (en) 2022-07-05
EP2727933A1 (en) 2014-05-07
US9556255B2 (en) 2017-01-31
CN102066408B (en) 2015-07-01
NZ602352A (en) 2014-06-27
PE20110599A1 (en) 2011-08-31
EP2297189A2 (en) 2011-03-23
BRPI0914780B1 (en) 2022-02-08
UA121093C2 (en) 2020-04-10
EP3470419A1 (en) 2019-04-17
EA201071312A1 (en) 2011-06-30
EP3904371A2 (en) 2021-11-03
EA030439B1 (en) 2018-08-31
EP3904371A3 (en) 2022-01-26
CA3008307C (en) 2020-12-15
EP3470419B1 (en) 2022-01-05
ZA201009045B (en) 2013-02-27
US8461421B2 (en) 2013-06-11
US20130310543A1 (en) 2013-11-21
EA201400248A1 (en) 2014-10-30
PE20140942A1 (en) 2014-08-06
US20130305412A1 (en) 2013-11-14
WO2009158470A2 (en) 2009-12-30
MX2010013910A (en) 2011-06-20
ES2911327T3 (en) 2022-05-18
AU2009262153A1 (en) 2009-12-30
EA020327B1 (en) 2014-10-30
US20170101447A1 (en) 2017-04-13
AU2009262153B2 (en) 2014-02-27
PH12014500606A1 (en) 2015-12-07
US20200055907A1 (en) 2020-02-20
CN105002189A (en) 2015-10-28
AR072316A1 (en) 2010-08-18
MX351227B (en) 2017-09-14
CA2729294A1 (en) 2009-12-30
WO2009158470A3 (en) 2010-04-29
US20100005543A1 (en) 2010-01-07
EP2727933B1 (en) 2019-01-09
CN102066408A (en) 2011-05-18
BRPI0914780A2 (en) 2020-07-14
CA2729294C (en) 2018-08-14
BR122021022392B1 (en) 2022-08-09
CL2010001436A1 (en) 2012-08-24
NZ589991A (en) 2012-09-28
CA3008307A1 (en) 2009-12-30

Similar Documents

Publication Publication Date Title
CO6351796A2 (en) TOXIN GENES AND METHODS FOR USE
AR114076A2 (en) PESTICIDED PROTEINS AND METHODS OF USE OF THEM
CO6630079A2 (en) Delta genes -endotoxins axmi221z, axmi222z, axmi223z, axmi224z and axmi225z and methods for use
AR080201A1 (en) DELTA-ENDOTOXINIC GENES OF BACILLUS THURINGIENSIS (AXMI218, AXMI219, AXMI220, AXMI226, AXMI227, AXMI228, AXMI229, AXMI230, AND AXMI231), AND METHODS FOR USE
AR075818A1 (en) AXMI-001, AXMI- 002, AXMI-030 AND AXMI -035 AND AXMI -045: TOXIN GENES AND METHODS FOR USE
AR087367A1 (en) AXMI 270 TOXIN GEN AND ITS METHODS OF USE
AR111197A2 (en) AXMI-031, AXMI-039, AXMI-040 AND AXMI-049, A FAMILY OF D-ENDOTOXIN GENES, AND METHODS TO USE THEM
AR077344A1 (en) FAMILY OF PESTICIATED GENES AXMI-192 AND METHODS FOR USE
AR074871A1 (en) PESTICIDE GENES OF BREVIBACILLUS AND METHODS FOR USE
AR090275A1 (en) GENE OF DELTA-ENDOTOXINA AXMI345 AND ITS METHODS OF USE
CO6390007A2 (en) GENES THAT CODE TOXINS AGAINST NEMATODES
AR068433A1 (en) SYNTHETIC GENES OF DELTA-ENDOTOXINA AXMI-004 AND METHODS OF USE OF THE SAME
CO6400155A2 (en) DELTA-ENDOTOXINE GEN AXMI-150 AND METHODS OF USE OF THE SAME
AR075799A1 (en) METHODS AND COMPOSITIONS FOR CONTROLLING PLANT PESTS
EA201171006A1 (en) VARIANT GENES AXMI-R1 DELTA-ENDOTOXIN AND METHODS FOR THEIR APPLICATION
AR090274A1 (en) GENE OF TOXIN AXMI335 OF BACILLUS THURINGIENSIS AND ITS METHODS OF USE
MX2021000709A (en) Axmi477, axmi482, axmi486 and axmi525 toxin genes from bacillus thuringiensis and methods for their use.
AR106371A1 (en) DELTA-ENDOTOXIN GEN AND METHODS FOR USE
MX387173B (en) AXMI669 AND AXMI991 TOXIN GENES AND METHODS FOR THEIR USE.
AR126609A2 (en) BP005 TOXIN GENE AND METHODS FOR ITS USE
UA117731C2 (en) AXMI277 TOXIN AGAINST NEMATODS AND ITS APPLICATION
AR097281A1 (en) AXMI440 TOXINE GEN AND ITS EMPLOYMENT METHODS
AR097280A1 (en) AXMI422 TOXIN GEN AND ITS EMPLOYMENT METHODS
MX2022004552A (en) NEW INSECT RESISTANCE GENES AND METHODS OF USE.
AR114190A2 (en) GENES THAT CODE TOXINS AGAINST NEMATODES

Legal Events

Date Code Title Description
FC Application refused