CO6311116A2 - Sistema para la expresion de peptidos sobre la superficie bacteriana de escherichia coli - Google Patents

Sistema para la expresion de peptidos sobre la superficie bacteriana de escherichia coli

Info

Publication number
CO6311116A2
CO6311116A2 CO10128683A CO10128683A CO6311116A2 CO 6311116 A2 CO6311116 A2 CO 6311116A2 CO 10128683 A CO10128683 A CO 10128683A CO 10128683 A CO10128683 A CO 10128683A CO 6311116 A2 CO6311116 A2 CO 6311116A2
Authority
CO
Colombia
Prior art keywords
peptides
expression
escherichia coli
bacterial surface
peptide
Prior art date
Application number
CO10128683A
Other languages
English (en)
Inventor
La Fuente Garcia Jose De Jesus De
Garcia-Menocal Mario Manuel Canales
Original Assignee
Consejo Superior Investigacion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior Investigacion filed Critical Consejo Superior Investigacion
Publication of CO6311116A2 publication Critical patent/CO6311116A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/29—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Richettsiales (O)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43527—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from ticks
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Insects & Arthropods (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Sistema de expresión de péptidos sobre la superficie bacteriana caracterizado porque comprende una región de anclaje a la membrana bacteriana y el péptido expuesto, donde la región de anclaje a la membrana bacteriana es cualquiera de las siguientes secuencias:a. Péptido que comprende la secuencia aminoacídica SEQ ID NO: 1; ob. Una secuencia aminoacídica con una identidad de al menos un 99%, 98%, 95%, 90%, o un 80% con Ia SEQ ID NO: 1.
CO10128683A 2008-04-16 2010-10-15 Sistema para la expresion de peptidos sobre la superficie bacteriana de escherichia coli CO6311116A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200801129A ES2352946B1 (es) 2008-04-16 2008-04-16 Sistema para la expresión de péptidos sobre la superficie bacteriana.

Publications (1)

Publication Number Publication Date
CO6311116A2 true CO6311116A2 (es) 2011-08-22

Family

ID=41198810

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10128683A CO6311116A2 (es) 2008-04-16 2010-10-15 Sistema para la expresion de peptidos sobre la superficie bacteriana de escherichia coli

Country Status (7)

Country Link
US (1) US8435537B2 (es)
EP (1) EP2281893B1 (es)
BR (1) BRPI0907340A2 (es)
CO (1) CO6311116A2 (es)
ES (1) ES2352946B1 (es)
MX (1) MX2010011384A (es)
WO (1) WO2009127766A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR102013026625B1 (pt) 2013-10-16 2022-04-26 Universidade Federal de Viçosa Vacina de peptídeos recombinantes para o controle de carrapatos e sequências de nucleotídeos codificadoras dos peptídeos recombinantes
US9580758B2 (en) 2013-11-12 2017-02-28 Luc Montagnier System and method for the detection and treatment of infection by a microbial agent associated with HIV infection

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0001717B1 (pt) * 2000-05-04 2013-10-08 Vacina sintética para o controle de carrapatos
US6979451B1 (en) * 2000-10-30 2005-12-27 The Board Of Regents For Oklahoma State University Recombinant antigen MSP1a from anaplasma marginale to reduce infections in ticks, vaccine compositions and methods of use

Also Published As

Publication number Publication date
EP2281893A4 (en) 2012-10-31
US8435537B2 (en) 2013-05-07
ES2352946A1 (es) 2011-03-07
BRPI0907340A2 (pt) 2016-07-05
EP2281893A1 (en) 2011-02-09
WO2009127766A1 (es) 2009-10-22
ES2352946B1 (es) 2012-01-23
EP2281893B1 (en) 2016-05-04
MX2010011384A (es) 2011-04-12
US20110097354A1 (en) 2011-04-28

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Legal Events

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