CO6190540A2 - Compuesto ceramico polimero y metodo - Google Patents

Compuesto ceramico polimero y metodo

Info

Publication number
CO6190540A2
CO6190540A2 CO09054994A CO09054994A CO6190540A2 CO 6190540 A2 CO6190540 A2 CO 6190540A2 CO 09054994 A CO09054994 A CO 09054994A CO 09054994 A CO09054994 A CO 09054994A CO 6190540 A2 CO6190540 A2 CO 6190540A2
Authority
CO
Colombia
Prior art keywords
composite material
polymer phase
poly
copolymer
alpha
Prior art date
Application number
CO09054994A
Other languages
English (en)
Inventor
Xinyin Liu
Mark Thomas Fulmer
Elliot Gruskin
Milvia Lepre
Original Assignee
Synthes Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthes Gmbh filed Critical Synthes Gmbh
Publication of CO6190540A2 publication Critical patent/CO6190540A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/20—Compounding polymers with additives, e.g. colouring
    • C08J3/205—Compounding polymers with additives, e.g. colouring in the presence of a continuous liquid phase
    • C08J3/21—Compounding polymers with additives, e.g. colouring in the presence of a continuous liquid phase the polymer being premixed with a liquid phase
    • C08J3/212—Compounding polymers with additives, e.g. colouring in the presence of a continuous liquid phase the polymer being premixed with a liquid phase and solid additives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/01—Use of inorganic substances as compounding ingredients characterized by their specific function
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
    • C08J2367/04—Polyesters derived from hydroxy carboxylic acids, e.g. lactones

Abstract

1.- Un material de compuesto, que comprende: una fase de polímero que incluye un poli(alfa-hidroxi éster) mezclado con un disolvente para mantener la fase de polímero en un estado no sólido; y una fase de cerámica bioabsorbible mezclada con la fase de polímero; en el cual, cuando el disolvente está en presencia de agua, éste se difunde de la fase de polímero para producir la solidificación de la fase de polímero y curar el material de compuesto. 2.- El material de compuesto de la reivindicación 1, en donde el disolvente se escoge de un grupo que consiste en n-metil-2-pirrolidona, 2-pirrolidona y sulfóxido de dimetilo. 3.- El material de compuesto de la reivindicación 1, en donde el poli(alfa-hidroxi éster) incluye uno o más de polilactida, policaprolactona, un copolímero que incluye poli(lactida-co-glicólido), un copolímero que incluye policaprolactona y poliactida, un copolímero que incluye polietilenglicol y uno o más poli (alfahidroxi ésteres) seleccionados del grupo consistente en policaprolactona, polilactida y poliglicólido. 4.- El material de compuesto de la reivindicación 1, en donde la fase de polímero incluye un copolímero. 5.- El material de compuesto de la reivindicación 1, en donde la fase de polímero incluye una mezcla física de un poli (alfa-hidroxi éster) y uno o más agentes hidrófilos. 6.- El material de compuesto de la reivindicación 1, en donde la cerámica bioabsorbible incluye uno o más de fosfato de calcio, sulfato de calcio y una mezcla de fosfato de calcio y sulfato de calcio. 7.- El material de compuesto de la reivindicación 1, en donde el material de compuesto está contenido en un estado no sólido en una cámara de almacenamiento dentro de un dispositivo de suministro. 8.- El material de compuesto de la reivindicación 7, en donde el dispositivo de suministro incluye una jeringa para mantener el material de compuesto en el estado no sólido antes de suministro.
CO09054994A 2006-10-31 2009-05-28 Compuesto ceramico polimero y metodo CO6190540A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85590406P 2006-10-31 2006-10-31

Publications (1)

Publication Number Publication Date
CO6190540A2 true CO6190540A2 (es) 2010-08-19

Family

ID=39344908

Family Applications (1)

Application Number Title Priority Date Filing Date
CO09054994A CO6190540A2 (es) 2006-10-31 2009-05-28 Compuesto ceramico polimero y metodo

Country Status (11)

Country Link
US (1) US20100041770A1 (es)
EP (1) EP2086604A2 (es)
JP (1) JP2010508071A (es)
KR (1) KR20090091710A (es)
CN (1) CN101600462A (es)
AU (1) AU2007314268A1 (es)
BR (1) BRPI0718068A2 (es)
CA (1) CA2668265A1 (es)
CO (1) CO6190540A2 (es)
WO (1) WO2008054794A2 (es)
ZA (1) ZA200903689B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1112095T3 (da) 1998-09-11 2003-03-17 Michael Dr Raschke Biologisk aktive implantater
US20100226956A1 (en) * 2009-03-06 2010-09-09 Per Kjellin Production of moldable bone substitute
US9358323B2 (en) * 2010-04-29 2016-06-07 Warsaw Orthopedic, Inc. Flowable ceramic putty
NL2011195C2 (en) 2013-07-18 2015-01-21 Xpand Biotechnology B V Method for producing an osteoinductive calcium phosphate and products thus obtained.
US10682442B2 (en) 2014-04-04 2020-06-16 University Of Kentucky Research Foundation Small molecule drug release from in situ forming degradable scaffolds incorporating hydrogels and bioceramic microparticles
US20170252480A1 (en) * 2014-09-01 2017-09-07 Kyushu University, National University Corporation Method of producing product inorganic compound and product inorganic compound
WO2016140626A1 (en) * 2015-03-04 2016-09-09 Agency For Science, Technology And Research Composite material for drug delivery
WO2021035795A1 (zh) * 2019-08-31 2021-03-04 深圳市立心科学有限公司 可塑形的人工骨复合材料及其制备方法
CN111110929B (zh) * 2020-02-15 2020-12-22 深圳脉动医学技术有限公司 一种高生物安全性心脏支架及其制造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6926903B2 (en) * 2001-12-04 2005-08-09 Inion Ltd. Resorbable polymer composition, implant and method of making implant
GB0302026D0 (en) * 2003-01-29 2003-02-26 Biocomposites Ltd Bioabsorbable implant
US20040230309A1 (en) * 2003-02-14 2004-11-18 Depuy Spine, Inc. In-situ formed intervertebral fusion device and method
EP1778760A4 (en) * 2004-07-30 2009-01-21 Univ Nebraska BIORESORBABLE COMPOSITIONS AND MANUFACTURING METHOD THEREFOR

Also Published As

Publication number Publication date
CN101600462A (zh) 2009-12-09
WO2008054794A2 (en) 2008-05-08
KR20090091710A (ko) 2009-08-28
EP2086604A2 (en) 2009-08-12
ZA200903689B (en) 2010-08-25
WO2008054794A3 (en) 2008-09-18
JP2010508071A (ja) 2010-03-18
BRPI0718068A2 (pt) 2013-10-29
CA2668265A1 (en) 2008-05-08
US20100041770A1 (en) 2010-02-18
AU2007314268A1 (en) 2008-05-08

Similar Documents

Publication Publication Date Title
CO6190540A2 (es) Compuesto ceramico polimero y metodo
ES2557988T3 (es) Método para tratar enfermedades de próstata basado en el suministro local de principios activos
BR112012032581A2 (pt) filme e adesivo que bloquea oxigênio
RU2014116247A (ru) Медицинские устройства, содержащие полимерные композиции с памятью формы
PE20060244A1 (es) Formulacion farmaceutica de deposito que contiene polietilenglicol de peso molecular menor a 600 daltones
UY32151A (es) Nuevo portador de agentes activos liberados de forma controlada
CY1113604T1 (el) Συστημα παροχης υγρου πολυμερους χαμηλου ιξωδους
AR053968A1 (es) Composiciones de polimeros antimicrobianas de liberacion controlada
AR070033A1 (es) Composiciones inyectables, sus procesos y usos
PE20071139A1 (es) Formulacion de liberacion sostenida que comprende octreotida y dos o mas polimeros de polilactido-co-glicolido
CL2007002304A1 (es) Solucion acuosa para el cierre de cateteres que comprende citrato y un parabeno dispersados o disueltos en la misma; dispositivo de infusion; kit para el cierre del cateter.
BRPI0816076B8 (pt) Filme de barreira de oxigênio ativa multicamada e embalagem
DE69914787D1 (de) Flüssige zusammensetzungen mit kontrollierter freigabe mit niedrigem initialfreisetzungsstoss des wirkstoffs
CO6390097A2 (es) Formulaciones para el cuidado oral que incrementa la cantidad de zinc soluble
WO2008054772A3 (en) Implantable elastomeric caprolactone depot compositions and uses thereof
ES2422681T3 (es) Formulación de fármaco de moléculas pequeñas de liberación prolongada
BRPI0712910B8 (pt) sistema de múltiplos componentes para uma composição de aumento ósseo injetável, e, composição de aumento ósseo injetável
CO6231004A2 (es) Material para implantes con base en un sistema de polimeros y el uso del mismo
EP2644213B1 (en) Drug-containing bioabsorbable fibers and implants
ATE370206T1 (de) Trennmittel auf acrly-basis, produkt mit dem trennmittel und prozess zur herstellung dieses produktes
ATE382337T1 (de) Bioabsorbierbare pharmazeutische zusammensetzung enthaltend einen plga-copolymer
DE602005013262D1 (de) Bioabsorbierbare polymere mit kalziumkarbonat
PE20030519A1 (es) Forma de dosificacion, dispositivo y metodos de tratamiento
ES2398033T3 (es) Exotermia controlada de formulaciones de cianoacrilato
JP2010508071A5 (es)

Legal Events

Date Code Title Description
FA Application withdrawn