CO5721009A2 - Proceso para preparar intermediarios de cefalosporinas mediante esteres de acido alfa-yodo-1-azetidinacetico y trialquilfosfitos - Google Patents

Proceso para preparar intermediarios de cefalosporinas mediante esteres de acido alfa-yodo-1-azetidinacetico y trialquilfosfitos

Info

Publication number
CO5721009A2
CO5721009A2 CO06090501A CO06090501A CO5721009A2 CO 5721009 A2 CO5721009 A2 CO 5721009A2 CO 06090501 A CO06090501 A CO 06090501A CO 06090501 A CO06090501 A CO 06090501A CO 5721009 A2 CO5721009 A2 CO 5721009A2
Authority
CO
Colombia
Prior art keywords
trialquilfosfitos
azetidinacetico
esteres
cephalosporine
intermediaries
Prior art date
Application number
CO06090501A
Other languages
English (en)
Inventor
Hiromasa Morita
Isao Nagakura
Timothy Norris
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of CO5721009A2 publication Critical patent/CO5721009A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1.- Un proceso para preparar un compuesto de la formula (IVa) en la que R1 es para-nitrobencilo o alilo y R2 es bencilo o bencilo sustituido;que comprende el paso de hacer reaccionar un compuesto de la formula (V) en la que R1 y R2 son como se definieron con anterioridad;con una sal de yoduro para producir el compuesto de la formula (IVa).2.- Un proceso para preparar un compuesto de la formula (III) en la que R1 es para-nitrobencilo o alilo; R2 es bencilo o bencilo sustituido; y R3 es alquilo C1-6;que comprende el paso de hacer reaccionar un compuesto de la formula (IVa) como se describe en la reivindicacion 1, con P(OR3)3 en un solvente.
CO06090501A 2004-03-09 2006-09-08 Proceso para preparar intermediarios de cefalosporinas mediante esteres de acido alfa-yodo-1-azetidinacetico y trialquilfosfitos CO5721009A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55184504P 2004-03-09 2004-03-09

Publications (1)

Publication Number Publication Date
CO5721009A2 true CO5721009A2 (es) 2007-01-31

Family

ID=34960709

Family Applications (1)

Application Number Title Priority Date Filing Date
CO06090501A CO5721009A2 (es) 2004-03-09 2006-09-08 Proceso para preparar intermediarios de cefalosporinas mediante esteres de acido alfa-yodo-1-azetidinacetico y trialquilfosfitos

Country Status (14)

Country Link
US (1) US20070208172A1 (es)
EP (1) EP1725568A1 (es)
JP (1) JP2007528386A (es)
CN (1) CN1930173A (es)
AR (1) AR048081A1 (es)
AU (1) AU2005225626B2 (es)
BR (1) BRPI0508595A (es)
CA (1) CA2557798A1 (es)
CO (1) CO5721009A2 (es)
IL (1) IL177297A0 (es)
NO (1) NO20064580L (es)
RU (1) RU2321590C1 (es)
WO (1) WO2005092900A1 (es)
ZA (1) ZA200606742B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2575261B (en) 2018-07-02 2022-03-09 Norbrook Lab Ltd Intermediates in the synthesis of C3-substituted cephalosporins
CN117186116B (zh) * 2023-09-07 2024-06-07 浙江荣耀生物科技股份有限公司 一种头孢维星中间体的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001997A (en) * 1990-07-24 1999-12-14 Bateson; John Hargreaves Cephalosporins and homologues, preparations and pharmaceutical compositions
GB2300856A (en) * 1995-05-16 1996-11-20 Pfizer Ltd Beta-lactam preparation
DE19704841A1 (de) * 1997-02-08 1998-08-13 Itt Mfg Enterprises Inc Verfahren und Vorrichtung zur Regelung der Längsdynamik eines Fahrzeugs
US6208106B1 (en) * 1999-12-22 2001-03-27 Visteon Global Technologies, Inc. Method and system for adjusting headway in an adaptive speed control system based on road surface coefficient of friction
GB0019124D0 (en) * 2000-08-03 2000-09-27 Pfizer Novel process
US6304808B1 (en) * 2000-09-09 2001-10-16 Kelsey-Hayes Company Enhanced active brake control system functionality through system integration with adaptive cruise control
WO2002046199A1 (en) * 2000-12-04 2002-06-13 Pfizer Products Inc. Process and ester derivatives useful for preparation of cephalosporins
AU2394302A (en) * 2000-12-04 2002-06-18 Pfizer Prod Inc Coupling process and intermediates useful for preparing cephalosphorins

Also Published As

Publication number Publication date
NO20064580L (no) 2006-10-09
WO2005092900A1 (en) 2005-10-06
CN1930173A (zh) 2007-03-14
BRPI0508595A (pt) 2007-08-21
ZA200606742B (en) 2008-09-25
RU2321590C1 (ru) 2008-04-10
AU2005225626A1 (en) 2005-10-06
US20070208172A1 (en) 2007-09-06
JP2007528386A (ja) 2007-10-11
IL177297A0 (en) 2006-12-10
AU2005225626B2 (en) 2008-03-13
EP1725568A1 (en) 2006-11-29
AR048081A1 (es) 2006-03-29
CA2557798A1 (en) 2005-10-06

Similar Documents

Publication Publication Date Title
RU2009105669A (ru) Способ получения 3-замещенных 2-амино-5-галогенбензамидов
CO6321190A2 (es) Compuestos mesoionicos de pirimidinio para el control de plagas de invertebrados
AR063429A1 (es) Anticuerpos anti- htnfalfa cristalinos
TW200637559A (en) 3-propenylcefem derivative
RU2008108079A (ru) Стабильные при хранении растворы оптических отбеливателей
AR063449A1 (es) Proceso quimico para derivados de quinazolina, intermediarios
EP3388426A3 (en) Compounds for protection of cells
EA200701738A1 (ru) Способ получения транс-1-((1r,3s)-6-хлор-3-фенилиндан-1-ил)-3,3-диметилпиперазина
FI20115816A0 (fi) Antimikrobinen ionomeerikoostumus sekä sen käytöt
RU2014153544A (ru) Стеклянный контейнер и способ его изготовления
RU2010131168A (ru) Сульфенамид, ускоритель вулканизации каучука, содержащий сульфенамид и способ получения ускорителя вулканизации
BR112015001769A2 (pt) Processo para a síntese de compostos de ureia substituída
BRPI0507422A (pt) processo para produção de ácido 2,5-dimetilfenilacético
BRPI0408160A (pt) processo para o preparo de ésteres do ácido nicotìnico substituìdo
CO5721009A2 (es) Proceso para preparar intermediarios de cefalosporinas mediante esteres de acido alfa-yodo-1-azetidinacetico y trialquilfosfitos
AR068755A1 (es) Metodo para la preparacion de acido montelukast en medio liquido ionico
DE502005003737D1 (de) Leitsalze fur galvanische zellen, deren herstellung und verwendung
AR051936A1 (es) Proceso para la preparacion de pirazoles
BR0315112A (pt) Sal de adição ácido, e, processo para a preparação de um composto
ATE466003T1 (de) Herstellung von 2-aminothiazol-5- carbonsäurederivaten
HRP20080440A2 (en) Process for production of 5-alkoxy-4-hydroxymethylpyrazole compound
AR058210A1 (es) Procedimiento para preparar 5-amino-3h-tiazolo[4,5-d]pirimidin-2-ona, un intermediario util para la preparacion de ciertos nucleosidos de tiazolo[4,5-d]pirimidina que actuan como inmunomoduladores.
CL2012000554A1 (es) Proceso para la preparacion de artemisina a partir de un derivado de anhidro; y el compuesto intermediario considerado.
BRPI0517302A (pt) processo de preparação de compostos de pirimidina
RU2010114928A (ru) Биологически активные вещества, подавляющие патогенные бактерии

Legal Events

Date Code Title Description
FC Application refused