CO4790169A1 - Procedimiento para la obtencion de antagonistas de receptore de endotelina del tipo sulfanilo - Google Patents
Procedimiento para la obtencion de antagonistas de receptore de endotelina del tipo sulfaniloInfo
- Publication number
- CO4790169A1 CO4790169A1 CO99013759A CO99013759A CO4790169A1 CO 4790169 A1 CO4790169 A1 CO 4790169A1 CO 99013759 A CO99013759 A CO 99013759A CO 99013759 A CO99013759 A CO 99013759A CO 4790169 A1 CO4790169 A1 CO 4790169A1
- Authority
- CO
- Colombia
- Prior art keywords
- procedure
- signifies
- sulfanil
- type
- receptor antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Procedimiento para la obtención de derivados de ácidocarboxílico de la fórmula general I:en la que R1 significa hidroxi, alcoxi, sulfonamidilo, amino, R2 significa alquilo, arilo o heteroarilo, eventualmente sustituido, R3 , R4 , R5 son idénticos o diferentes ysignifican independientemente alquilo o arilo, eventualmente sustituido. Por reacción nucleófila de un derivado de ácido carboxílico de la fórmula II con un sulfuro de la fórmula III en la que X significa SR6 o SO2 R6 R6 significa alquilo o arilo, eventualmente sustituido.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19809635A DE19809635A1 (de) | 1998-03-06 | 1998-03-06 | Verfahren zur Darstellung von Endothelinrezeptorantagonisten vom Sulfanyltyp |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4790169A1 true CO4790169A1 (es) | 1999-05-31 |
Family
ID=7859948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO99013759A CO4790169A1 (es) | 1998-03-06 | 1999-03-05 | Procedimiento para la obtencion de antagonistas de receptore de endotelina del tipo sulfanilo |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6235903B1 (es) |
| EP (1) | EP1060168A2 (es) |
| JP (1) | JP2002505319A (es) |
| KR (1) | KR20010041631A (es) |
| CN (1) | CN1292783A (es) |
| AR (1) | AR018145A1 (es) |
| AU (1) | AU3408799A (es) |
| BG (1) | BG104722A (es) |
| BR (1) | BR9908585A (es) |
| CA (1) | CA2322226A1 (es) |
| CO (1) | CO4790169A1 (es) |
| DE (1) | DE19809635A1 (es) |
| HR (1) | HRP20000649A2 (es) |
| HU (1) | HUP0100857A3 (es) |
| ID (1) | ID26348A (es) |
| IL (1) | IL137538A0 (es) |
| NO (1) | NO20004422L (es) |
| PL (1) | PL343426A1 (es) |
| SK (1) | SK12012000A3 (es) |
| TR (1) | TR200002577T2 (es) |
| WO (1) | WO1999044988A2 (es) |
| ZA (1) | ZA991779B (es) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU620573B2 (en) * | 1987-11-27 | 1992-02-20 | Societe Nationale Elf Aquitaine | Process for phenol alkylthiolation and its application to the synthesis of 4-acyl-2-alkylthiophenols |
| DE4313412A1 (de) | 1993-04-23 | 1994-10-27 | Basf Ag | 3-(Het)aryl-Carbonsäurederivate, Verfahren und Zwischenprodukte zu ihrer Herstellung |
| DE4411225A1 (de) | 1994-03-31 | 1995-10-05 | Basf Ag | Verwendung von Carbonsäurederivaten als Arzneimittel |
| DE19533023B4 (de) | 1994-10-14 | 2007-05-16 | Basf Ag | Neue Carbonsäurederivate, ihre Herstellung und Verwendung |
| US5719292A (en) * | 1997-03-27 | 1998-02-17 | Eastman Kodak Company | Process for preparing a thioether compound |
-
1998
- 1998-03-06 DE DE19809635A patent/DE19809635A1/de not_active Withdrawn
-
1999
- 1999-02-25 US US09/622,771 patent/US6235903B1/en not_active Expired - Fee Related
- 1999-02-25 IL IL13753899A patent/IL137538A0/xx unknown
- 1999-02-25 KR KR1020007009830A patent/KR20010041631A/ko not_active Application Discontinuation
- 1999-02-25 AU AU34087/99A patent/AU3408799A/en not_active Abandoned
- 1999-02-25 WO PCT/EP1999/001209 patent/WO1999044988A2/de not_active Application Discontinuation
- 1999-02-25 JP JP2000534532A patent/JP2002505319A/ja active Pending
- 1999-02-25 PL PL99343426A patent/PL343426A1/xx unknown
- 1999-02-25 BR BR9908585-2A patent/BR9908585A/pt not_active IP Right Cessation
- 1999-02-25 EP EP99915535A patent/EP1060168A2/de not_active Withdrawn
- 1999-02-25 CA CA002322226A patent/CA2322226A1/en not_active Abandoned
- 1999-02-25 TR TR2000/02577T patent/TR200002577T2/xx unknown
- 1999-02-25 CN CN998037222A patent/CN1292783A/zh active Pending
- 1999-02-25 SK SK1201-2000A patent/SK12012000A3/sk unknown
- 1999-02-25 ID IDW20001720A patent/ID26348A/id unknown
- 1999-02-25 HU HU0100857A patent/HUP0100857A3/hu unknown
- 1999-03-05 ZA ZA9901779A patent/ZA991779B/xx unknown
- 1999-03-05 AR ARP990100941A patent/AR018145A1/es not_active Application Discontinuation
- 1999-03-05 CO CO99013759A patent/CO4790169A1/es unknown
-
2000
- 2000-08-28 BG BG104722A patent/BG104722A/xx unknown
- 2000-09-05 NO NO20004422A patent/NO20004422L/no not_active Application Discontinuation
- 2000-10-03 HR HR20000649A patent/HRP20000649A2/hr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20004422D0 (no) | 2000-09-05 |
| WO1999044988A3 (de) | 1999-11-11 |
| HRP20000649A2 (en) | 2001-06-30 |
| WO1999044988A2 (de) | 1999-09-10 |
| EP1060168A2 (de) | 2000-12-20 |
| BG104722A (en) | 2001-05-31 |
| NO20004422L (no) | 2000-09-05 |
| PL343426A1 (en) | 2001-08-13 |
| JP2002505319A (ja) | 2002-02-19 |
| AR018145A1 (es) | 2001-10-31 |
| BR9908585A (pt) | 2000-11-21 |
| TR200002577T2 (tr) | 2000-11-21 |
| CA2322226A1 (en) | 1999-09-10 |
| US6235903B1 (en) | 2001-05-22 |
| IL137538A0 (en) | 2001-07-24 |
| ZA991779B (en) | 2000-10-11 |
| HUP0100857A3 (en) | 2001-12-28 |
| DE19809635A1 (de) | 1999-09-09 |
| HUP0100857A2 (hu) | 2001-08-28 |
| CN1292783A (zh) | 2001-04-25 |
| ID26348A (id) | 2000-12-14 |
| SK12012000A3 (sk) | 2001-01-18 |
| AU3408799A (en) | 1999-09-20 |
| KR20010041631A (ko) | 2001-05-25 |
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