CO4700484A1 - Compuestos y metodos relacionados con tuberculosis . - Google Patents

Compuestos y metodos relacionados con tuberculosis .

Info

Publication number
CO4700484A1
CO4700484A1 CO97059667A CO97059667A CO4700484A1 CO 4700484 A1 CO4700484 A1 CO 4700484A1 CO 97059667 A CO97059667 A CO 97059667A CO 97059667 A CO97059667 A CO 97059667A CO 4700484 A1 CO4700484 A1 CO 4700484A1
Authority
CO
Colombia
Prior art keywords
ala
pro
gly
thr
ser
Prior art date
Application number
CO97059667A
Other languages
English (en)
Inventor
Steven G Reed
A W Skeiky Yasir
David C Dillon
Antonio Campos-Neto
Raymond Houghton
Thomas S Vedvick
Daniel R Twardzik
Michael J Lodes
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/818,112 external-priority patent/US6290969B1/en
Application filed by Corixa Corp filed Critical Corixa Corp
Publication of CO4700484A1 publication Critical patent/CO4700484A1/es

Links

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  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Un polipéptido que comprende una porción inmunogénica de unantígeno soluble de M. tuberculosis, o una variante de dicho antígeno que difiere únicamente en sustituciones conservativas y/o modificaciones, donde dicho antígeno tiene una secuencia N-terminal seleccionada a partir del grupo que consiste de: (a) Asp-Pro-Tal-Bal-Asp-Ala-Bal-Ile-Asn-Thr-Thr- Cys-Asn-Tyr-Gly-Gln-Val-Val-Ala-Ala-Leu; (SEQ-ID No. 120) (b) Ala-Bal-Glu-Ser-Gly-Met-Leu-Ala-Leu-Gly-Thr- Pro-Ala-Pro-Ser; (SEQ ID No. 121) (c) Ala-Ala-Met-Lys-Pro-Arg-Thr-Gly-Asp-Gly-Pro- Leu-Glu-Ala-Ala-Lys-Glu-Gly-Arg; (SEQ ID No.122) (d) Tyr-Trp-Cys-Pro-Gly-Gln-Pro-Phe-Asp-Pro-Ala- Trp-Gly-Pro; (SEQ. ID No.123) (e) Asp-Ile-Gly-Ser-Glu-Ser-Thr-Glu-Asp-Gln-Gln- Xaa-Ala-Val-(SEQ ID No. 124) (f) Ala-Glu-Glu-Ser-Ile-Ser-Thr-Xaa-Ile-Val-Pro-;(SEQ. ID No.125) (g) Asp-Pro-Glu-Pro-Ala-Pro-Pro-Val-Pro-Thr-Thr- Ala-Ala-Ser-Pro-Pro-Ser; (SEQ ID No.126) (h) Ala-Pro-Lys-Thr-Tyr-Xaa-Glu-Glu-Leu-Lys-Gly-Thr- Asp-Thr-Gly; (SEQ ID No. 127) (i) Asp-Pro-Ala-Ser-Ala-Pro-Asp-Val-Pro-Thr-Ala- Ala-Gln-Leu-Thr-Ser-Leu-Leu-Asn-Ser-Leu-Ala-Asp- Pro-Asn-Val-Ser-Phe-Ala-Asn; (SEQ ID No. 128) y (j) Ala-Pro-Glu-Ser-Gly-Ala-Gly-Leu-Gly-Gly-Thr- Val-Gln-Ala-Gly-; (SEQ ID No. 136).
CO97059667A 1996-10-11 1997-10-10 Compuestos y metodos relacionados con tuberculosis . CO4700484A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73051096A 1996-10-11 1996-10-11
US08/818,112 US6290969B1 (en) 1995-09-01 1997-03-13 Compounds and methods for immunotherapy and diagnosis of tuberculosis

Publications (1)

Publication Number Publication Date
CO4700484A1 true CO4700484A1 (es) 1998-12-29

Family

ID=40930091

Family Applications (1)

Application Number Title Priority Date Filing Date
CO97059667A CO4700484A1 (es) 1996-10-11 1997-10-10 Compuestos y metodos relacionados con tuberculosis .

Country Status (2)

Country Link
AR (1) AR010517A1 (es)
CO (1) CO4700484A1 (es)

Also Published As

Publication number Publication date
AR010517A1 (es) 2000-06-28

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