CO2023013766A2 - Compuestos carboxi-benzimidazol moduladores de glp-1r - Google Patents

Compuestos carboxi-benzimidazol moduladores de glp-1r

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Publication number
CO2023013766A2
CO2023013766A2 CONC2023/0013766A CO2023013766A CO2023013766A2 CO 2023013766 A2 CO2023013766 A2 CO 2023013766A2 CO 2023013766 A CO2023013766 A CO 2023013766A CO 2023013766 A2 CO2023013766 A2 CO 2023013766A2
Authority
CO
Colombia
Prior art keywords
glp
carboxy
modulating
benzimidazole compounds
compounds
Prior art date
Application number
CONC2023/0013766A
Other languages
English (en)
Spanish (es)
Inventor
Elbert Chin
Chienhung Chou
Zheng-Yu Yang
Scott D Schroeder
Gediminas J Brizgys
James S Cassidy
Chao-I Hung
Rhiannon Thomas-Tran
Nathan E Wright
David W Lin
Michael L Mitchell
Megan K Armstrong
Ezra Roberts
James G Taylor
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of CO2023013766A2 publication Critical patent/CO2023013766A2/es

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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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IL306110A (en) 2021-04-21 2023-11-01 Gilead Sciences Inc Carboxy-benzimidazole glp-1r modulating compounds
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WO2023111144A1 (en) 2021-12-16 2023-06-22 Astrazeneca Ab Certain 3-azabicyclo[3.1.0]hexanes as glp-1 receptor modulators
US20250042882A1 (en) 2021-12-16 2025-02-06 Astrazeneca Ab Certain 3-azabicyclo[3.1.0]hexanes as glp-1 receptor modulators
EP4592285A1 (en) 2022-09-22 2025-07-30 Shionogi & Co., Ltd. Fused ring compound having glp-1 receptor agonist effect
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KR20250085816A (ko) 2022-11-16 2025-06-12 일라이 릴리 앤드 캄파니 글루카곤-유사 펩티드 1 수용체 효능제
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