CO2022018016A2 - Composiciones y métodos para inhibir la proliferación de células musculares lisas vasculares - Google Patents

Composiciones y métodos para inhibir la proliferación de células musculares lisas vasculares

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Publication number
CO2022018016A2
CO2022018016A2 CONC2022/0018016A CO2022018016A CO2022018016A2 CO 2022018016 A2 CO2022018016 A2 CO 2022018016A2 CO 2022018016 A CO2022018016 A CO 2022018016A CO 2022018016 A2 CO2022018016 A2 CO 2022018016A2
Authority
CO
Colombia
Prior art keywords
methods
cell proliferation
smooth muscle
muscle cell
vascular smooth
Prior art date
Application number
CONC2022/0018016A
Other languages
English (en)
Inventor
Frank Rutsch
David Thompson
Yvonne Nitschke
Robert Terkeltaub
Original Assignee
Inozyme Pharma Inc
Univ Muenster Westfaelische Wilhelms
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inozyme Pharma Inc, Univ Muenster Westfaelische Wilhelms filed Critical Inozyme Pharma Inc
Publication of CO2022018016A2 publication Critical patent/CO2022018016A2/es

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Abstract

La presente descripción proporciona composiciones y métodos para tratar la proliferación de células musculares lisas vasculares en un sujeto que no tiene una deficiencia de ectonucleótido pirofosfatasa fosfodiesterasa-1 (ENPP1) que resulta en una enfermedad patológica de calcificación u osificación mediante la administración de un agente ENPP1 o un agente ENPP3.
CONC2022/0018016A 2020-05-27 2022-12-13 Composiciones y métodos para inhibir la proliferación de células musculares lisas vasculares CO2022018016A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063030870P 2020-05-27 2020-05-27
PCT/US2021/034576 WO2021243054A1 (en) 2020-05-27 2021-05-27 Compositions and methods for inhibiting vascular smooth muscle cell proliferation

Publications (1)

Publication Number Publication Date
CO2022018016A2 true CO2022018016A2 (es) 2023-01-26

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CONC2022/0018016A CO2022018016A2 (es) 2020-05-27 2022-12-13 Composiciones y métodos para inhibir la proliferación de células musculares lisas vasculares

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US (1) US20230330307A1 (es)
EP (1) EP4157328A4 (es)
JP (1) JP2023527365A (es)
KR (1) KR20230047334A (es)
CN (1) CN116367851A (es)
AU (1) AU2021281267A1 (es)
CA (1) CA3180119A1 (es)
CO (1) CO2022018016A2 (es)
IL (1) IL298482A (es)
MX (1) MX2022014733A (es)
TW (1) TW202214293A (es)
WO (1) WO2021243054A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023196820A2 (en) * 2022-04-04 2023-10-12 Inozyme Pharma, Inc. Treatment of enpp1 deficiency and abcc6 deficiency
CN115433776B (zh) * 2022-09-30 2023-12-22 中国医学科学院阜外医院 Ccn3在调控血管平滑肌细胞钙化中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11039942B2 (en) * 2006-06-13 2021-06-22 Sino Medical Sciences Technology Inc. Drug eluting stent and method of use of the same for enabling restoration of functional endothelial cell layers
EP3471747A1 (en) * 2016-06-16 2019-04-24 Alexion Pharmaceuticals, Inc. Methods of treating myointimal proliferation
CA3096821A1 (en) * 2017-09-27 2019-04-04 Inozyme Pharma, Inc. Methods of improving cardiovascular function and treating cardiovascular disease using a recombinant ectonucleotide pyrophosphatase phosphodiesterase (npp1)
WO2020047520A1 (en) * 2018-08-31 2020-03-05 Yale University Enpp1 polypeptides and methods of using same

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JP2023527365A (ja) 2023-06-28
TW202214293A (zh) 2022-04-16
CA3180119A1 (en) 2021-12-02
CN116367851A (zh) 2023-06-30
WO2021243054A1 (en) 2021-12-02
IL298482A (en) 2023-01-01
MX2022014733A (es) 2023-03-14
EP4157328A1 (en) 2023-04-05
KR20230047334A (ko) 2023-04-07
EP4157328A4 (en) 2024-06-05
AU2021281267A1 (en) 2023-01-05
US20230330307A1 (en) 2023-10-19

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