CO2022012207A2 - Inhaladores de dosis medida presurizada que comprenden una formulación farmacéutica amortiguada - Google Patents
Inhaladores de dosis medida presurizada que comprenden una formulación farmacéutica amortiguadaInfo
- Publication number
- CO2022012207A2 CO2022012207A2 CONC2022/0012207A CO2022012207A CO2022012207A2 CO 2022012207 A2 CO2022012207 A2 CO 2022012207A2 CO 2022012207 A CO2022012207 A CO 2022012207A CO 2022012207 A2 CO2022012207 A2 CO 2022012207A2
- Authority
- CO
- Colombia
- Prior art keywords
- metered dose
- pressurized metered
- pharmaceutical formulation
- dose inhalers
- buffered pharmaceutical
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- KUVIULQEHSCUHY-XYWKZLDCSA-N Beclometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)COC(=O)CC)(OC(=O)CC)[C@@]1(C)C[C@@H]2O KUVIULQEHSCUHY-XYWKZLDCSA-N 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- 229950000210 beclometasone dipropionate Drugs 0.000 abstract 1
- BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 abstract 1
- 229960002848 formoterol Drugs 0.000 abstract 1
- 229940071648 metered dose inhaler Drugs 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D127/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Coating compositions based on derivatives of such polymers
- C09D127/02—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Coating compositions based on derivatives of such polymers not modified by chemical after-treatment
- C09D127/12—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Coating compositions based on derivatives of such polymers not modified by chemical after-treatment containing fluorine atoms
- C09D127/18—Homopolymers or copolymers of tetrafluoroethene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0238—General characteristics of the apparatus characterised by a particular materials the material being a coating or protective layer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Otolaryngology (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Dispersion Chemistry (AREA)
- Materials Engineering (AREA)
- Wood Science & Technology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Abstract
La presente invención se relaciona de manera general con una formulación en aerosol que comprende formoterol y dipropionato de beclometasona, la formulación está contenida en una lata recubierta, particularmente útil para usarse en un inhalador de dosis medida presurizada para el tratamiento de enfermedades respiratorias.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20153973 | 2020-01-28 | ||
EP20214091 | 2020-12-15 | ||
PCT/EP2021/051669 WO2021151857A1 (en) | 2020-01-28 | 2021-01-26 | Pressurised metered dose inhalers comprising a buffered pharmaceutical formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2022012207A2 true CO2022012207A2 (es) | 2022-11-08 |
Family
ID=74285492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2022/0012207A CO2022012207A2 (es) | 2020-01-28 | 2022-08-26 | Inhaladores de dosis medida presurizada que comprenden una formulación farmacéutica amortiguada |
Country Status (16)
Country | Link |
---|---|
US (1) | US20230347080A1 (es) |
EP (1) | EP4096623A1 (es) |
JP (1) | JP2023511615A (es) |
KR (1) | KR20220133193A (es) |
CN (3) | CN113244490A (es) |
AU (1) | AU2021213883A1 (es) |
BR (1) | BR112022012361A2 (es) |
CA (1) | CA3163599A1 (es) |
CL (1) | CL2022002008A1 (es) |
CO (1) | CO2022012207A2 (es) |
GB (1) | GB2593283B (es) |
GE (1) | GEP20247594B (es) |
IL (1) | IL294804A (es) |
MX (1) | MX2022008440A (es) |
PE (1) | PE20221867A1 (es) |
WO (1) | WO2021151857A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024033941A1 (en) * | 2022-08-10 | 2024-02-15 | Cipla Limited | A pharmaceutical composition of salbutamol and pharmaceutical green propellant |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ306280A (en) | 1995-04-14 | 1999-07-29 | Glaxo Wellcome Inc | Metered dose inhaler for salmeterol |
BR0015884A (pt) | 2000-05-22 | 2003-07-08 | Chiesi Farma Spa | Formulações de soluções farmacêuticas estáveis para inaladores de dose medida pressurizados |
EP1241113A1 (en) * | 2001-03-12 | 2002-09-18 | CHIESI FARMACEUTICI S.p.A. | Inhaler with means for improving chemical stability of medicinal aerosol solution contained therein |
MEP30108A (en) | 2002-03-01 | 2010-06-10 | Chiesi Farmaceutici S P | Formoterol superfine formulation |
US9308199B2 (en) | 2004-04-29 | 2016-04-12 | Honeywell International Inc. | Medicament formulations |
CN1301747C (zh) * | 2004-11-30 | 2007-02-28 | 深圳市海王英特龙生物技术股份有限公司 | 一种蛋白药物微囊及其吸入性气雾剂 |
FR2895260B1 (fr) * | 2005-12-23 | 2009-02-20 | Servier Lab | Nouvelle composition pharmaceutique a base d'huile essentielle pour pulverisation nasale et/ou buccale |
GB201108039D0 (en) | 2011-05-13 | 2011-06-29 | Mexichem Amanco Holding Sa | Compositions |
AU2014375301B2 (en) * | 2013-12-30 | 2020-03-26 | Chiesi Farmaceutici S.P.A. | Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination |
EA033228B1 (ru) * | 2013-12-30 | 2019-09-30 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Находящаяся под давлением стабильная аэрозольная композиция комбинации гликопиррония бромида и формотерола в форме раствора |
WO2016018892A1 (en) * | 2014-07-29 | 2016-02-04 | 3M Innovative Properties Company | Method of preparing a pharmaceutical composition |
CA3007050C (en) * | 2015-12-04 | 2020-12-08 | Mexichem Fluor S.A. De C.V. | Pharmaceutical composition comprising a formoterol compound |
US10098837B2 (en) * | 2016-07-28 | 2018-10-16 | Chiesi Farmaceutici S.P.A. | Combination therapy for COPD |
ES2968453T3 (es) | 2016-09-19 | 2024-05-09 | Mexichem Fluor Sa De Cv | Composición farmacéutica que comprende glicopirrolato |
JP6781832B2 (ja) * | 2016-09-19 | 2020-11-04 | メキシケム フロー エセ・ア・デ・セ・ヴェ | 医薬組成物 |
GB2554091A (en) * | 2016-09-19 | 2018-03-28 | Mexichem Fluor Sa De Cv | Pharmaceutical composition |
GB2558191A (en) * | 2016-09-19 | 2018-07-11 | Mexichem Fluor Sa De Cv | Pharmaceutical composition |
GB2554088A (en) * | 2016-09-19 | 2018-03-28 | Mexichem Fluor Sa De Cv | Pharmaceautical composition |
CN112203649A (zh) * | 2018-06-07 | 2021-01-08 | 金德瓦药物控释有限公司 | 氟替卡松和维兰特罗制剂以及吸入器 |
-
2021
- 2021-01-26 JP JP2022545798A patent/JP2023511615A/ja active Pending
- 2021-01-26 MX MX2022008440A patent/MX2022008440A/es unknown
- 2021-01-26 CN CN202110100918.3A patent/CN113244490A/zh active Pending
- 2021-01-26 PE PE2022001478A patent/PE20221867A1/es unknown
- 2021-01-26 CN CN202311490675.4A patent/CN117599290A/zh active Pending
- 2021-01-26 CA CA3163599A patent/CA3163599A1/en active Pending
- 2021-01-26 KR KR1020227024888A patent/KR20220133193A/ko unknown
- 2021-01-26 WO PCT/EP2021/051669 patent/WO2021151857A1/en active Application Filing
- 2021-01-26 IL IL294804A patent/IL294804A/en unknown
- 2021-01-26 US US17/760,354 patent/US20230347080A1/en active Pending
- 2021-01-26 EP EP21702003.1A patent/EP4096623A1/en active Pending
- 2021-01-26 BR BR112022012361A patent/BR112022012361A2/pt unknown
- 2021-01-26 AU AU2021213883A patent/AU2021213883A1/en active Pending
- 2021-01-26 GE GEAP202116025A patent/GEP20247594B/en unknown
- 2021-01-26 GB GB2101048.3A patent/GB2593283B/en active Active
- 2021-01-26 CN CN202180010439.0A patent/CN115003282A/zh active Pending
-
2022
- 2022-07-26 CL CL2022002008A patent/CL2022002008A1/es unknown
- 2022-08-26 CO CONC2022/0012207A patent/CO2022012207A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
AU2021213883A1 (en) | 2022-07-21 |
US20230347080A1 (en) | 2023-11-02 |
KR20220133193A (ko) | 2022-10-04 |
BR112022012361A2 (pt) | 2022-09-06 |
CL2022002008A1 (es) | 2023-02-24 |
GEP20247594B (en) | 2024-02-12 |
CA3163599A1 (en) | 2021-08-05 |
GB2593283B (en) | 2023-09-13 |
EP4096623A1 (en) | 2022-12-07 |
PE20221867A1 (es) | 2022-12-02 |
MX2022008440A (es) | 2022-08-02 |
GB202101048D0 (en) | 2021-03-10 |
CN115003282A (zh) | 2022-09-02 |
CN113244490A (zh) | 2021-08-13 |
JP2023511615A (ja) | 2023-03-20 |
GB2593283A (en) | 2021-09-22 |
CN117599290A (zh) | 2024-02-27 |
IL294804A (en) | 2022-09-01 |
WO2021151857A1 (en) | 2021-08-05 |
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