CO2020009476A2 - Anti-cd25 para depleción de células específicas de tumor - Google Patents

Anti-cd25 para depleción de células específicas de tumor

Info

Publication number
CO2020009476A2
CO2020009476A2 CONC2020/0009476A CO2020009476A CO2020009476A2 CO 2020009476 A2 CO2020009476 A2 CO 2020009476A2 CO 2020009476 A CO2020009476 A CO 2020009476A CO 2020009476 A2 CO2020009476 A2 CO 2020009476A2
Authority
CO
Colombia
Prior art keywords
specific cell
tumor specific
cell depletion
antibodies
present disclosure
Prior art date
Application number
CONC2020/0009476A
Other languages
English (en)
Inventor
Mark Brown
James Geoghegan
Anne Goubier
Corzo Beatriz Goyenechea
Pascal Merchiers
Kevin Moulder
Bianka Prinz
Sergio Quezada
Josephine Salimu
Original Assignee
Cancer Research Tech Ltd
Tusk Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1804028.7A external-priority patent/GB201804028D0/en
Priority claimed from GBGB1804029.5A external-priority patent/GB201804029D0/en
Priority claimed from GBGB1804027.9A external-priority patent/GB201804027D0/en
Priority claimed from PCT/EP2018/056312 external-priority patent/WO2018167104A1/en
Priority claimed from PCT/EP2019/056248 external-priority patent/WO2019175216A1/en
Application filed by Cancer Research Tech Ltd, Tusk Therapeutics Ltd filed Critical Cancer Research Tech Ltd
Publication of CO2020009476A2 publication Critical patent/CO2020009476A2/es

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    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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Abstract

La presente divulgación proporciona secuencias de anticuerpos encontradas en anticuerpos que se unen a CD25 humana. En particular, la presente divulgación proporciona secuencias de anticuerpos anti–CD25 humanos, que no bloquean la unión de CD25 a IL–2 ni la señalización de IL–2. Los anticuerpos y las porciones de unión a antígeno de los mismos que incluyen dichas secuencias se pueden usar en composiciones farmacéuticas y métodos de tratamiento, en particular para tratar el cáncer.
CONC2020/0009476A 2018-03-13 2020-07-29 Anti-cd25 para depleción de células específicas de tumor CO2020009476A2 (es)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201862642218P 2018-03-13 2018-03-13
US201862642243P 2018-03-13 2018-03-13
US201862642230P 2018-03-13 2018-03-13
US201862642232P 2018-03-13 2018-03-13
US201862642248P 2018-03-13 2018-03-13
GBGB1804028.7A GB201804028D0 (en) 2018-03-13 2018-03-13 Anti-CD25 antibody agents
GBGB1804029.5A GB201804029D0 (en) 2018-03-13 2018-03-13 Anti-CD25 antibody agents
GBGB1804027.9A GB201804027D0 (en) 2018-03-13 2018-03-13 Anti-CD25 antibody agents
PCT/EP2018/056312 WO2018167104A1 (en) 2017-03-17 2018-03-13 Fc-optimized anti-cd25 for tumour specific cell depletion
PCT/EP2019/056248 WO2019175216A1 (en) 2018-03-13 2019-03-13 Anti-cd25 for tumour specific cell depletion

Publications (1)

Publication Number Publication Date
CO2020009476A2 true CO2020009476A2 (es) 2020-10-30

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ID=73006482

Family Applications (3)

Application Number Title Priority Date Filing Date
CONC2020/0009476A CO2020009476A2 (es) 2018-03-13 2020-07-29 Anti-cd25 para depleción de células específicas de tumor
CONC2020/0009743A CO2020009743A2 (es) 2018-03-13 2020-08-06 Agentes anticuerpos anti–cd25
CONC2020/0009758A CO2020009758A2 (es) 2018-03-13 2020-08-06 Agentes anticuerpos anti–cd25

Family Applications After (2)

Application Number Title Priority Date Filing Date
CONC2020/0009743A CO2020009743A2 (es) 2018-03-13 2020-08-06 Agentes anticuerpos anti–cd25
CONC2020/0009758A CO2020009758A2 (es) 2018-03-13 2020-08-06 Agentes anticuerpos anti–cd25

Country Status (9)

Country Link
US (1) US20240309101A1 (es)
CL (4) CL2020002339A1 (es)
CO (3) CO2020009476A2 (es)
IL (3) IL276995A (es)
MA (2) MA51997A (es)
MX (3) MX2020008769A (es)
PH (3) PH12020551453A1 (es)
RU (2) RU2020128108A (es)
ZA (1) ZA202004771B (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11697688B2 (en) 2018-03-13 2023-07-11 Tusk Therapeutics Ltd. Anti-CD25 for tumour specific cell depletion
US11879014B2 (en) 2017-03-17 2024-01-23 Tusk Therapeutics Ltd. Method of treating cancer or depleting regulatory T cells in a subject by administering a human IGG1 anti-CD25 antibody

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11879014B2 (en) 2017-03-17 2024-01-23 Tusk Therapeutics Ltd. Method of treating cancer or depleting regulatory T cells in a subject by administering a human IGG1 anti-CD25 antibody
US11697688B2 (en) 2018-03-13 2023-07-11 Tusk Therapeutics Ltd. Anti-CD25 for tumour specific cell depletion
US11787866B2 (en) 2018-03-13 2023-10-17 Tusk Therapeutics Ltd. Anti-CD25 antibody agents
US11802161B2 (en) 2018-03-13 2023-10-31 Tusk Therapeutics Ltd. Anti-CD25 for tumour specific cell depletion
US11802160B2 (en) 2018-03-13 2023-10-31 Tusk Therapeutics Ltd. Anti-CD25 antibody agents
US11814434B2 (en) 2018-03-13 2023-11-14 Tusk Therapeutics Ltd. Anti-CD25 for tumour specific cell depletion
US11851494B2 (en) 2018-03-13 2023-12-26 Tusk Therapeutics Ltd. Anti-CD25 for tumour specific cell depletion
US11873341B2 (en) 2018-03-13 2024-01-16 Tusk Therapeutics Ltd. Anti-CD25 for tumour specific cell depletion
US11919960B2 (en) 2018-03-13 2024-03-05 Tusk Therapeutics Ltd. Anti-CD25 antibody agents

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