MX2020008768A - Agentes anticuerpos anti-cd25. - Google Patents

Agentes anticuerpos anti-cd25.

Info

Publication number
MX2020008768A
MX2020008768A MX2020008768A MX2020008768A MX2020008768A MX 2020008768 A MX2020008768 A MX 2020008768A MX 2020008768 A MX2020008768 A MX 2020008768A MX 2020008768 A MX2020008768 A MX 2020008768A MX 2020008768 A MX2020008768 A MX 2020008768A
Authority
MX
Mexico
Prior art keywords
specific cell
cell depletion
tumour specific
antibody
antibodies
Prior art date
Application number
MX2020008768A
Other languages
English (en)
Inventor
Pascal Merchiers
Anne Goubier
James Geoghegan
Sergio Quezada
Bianka Prinz
Josephine Salimu
Kevin Moulder
Corzo Beatriz Goyenechea
Mark Brown
Original Assignee
Tusk Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1804028.7A external-priority patent/GB201804028D0/en
Priority claimed from GBGB1804029.5A external-priority patent/GB201804029D0/en
Priority claimed from GBGB1804027.9A external-priority patent/GB201804027D0/en
Priority claimed from PCT/EP2018/056312 external-priority patent/WO2018167104A1/en
Application filed by Tusk Therapeutics Ltd filed Critical Tusk Therapeutics Ltd
Priority claimed from PCT/EP2019/056248 external-priority patent/WO2019175216A1/en
Publication of MX2020008768A publication Critical patent/MX2020008768A/es

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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A—HUMAN NECESSITIES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39566—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against immunoglobulins, e.g. anti-idiotypic antibodies
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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Abstract

La presente divulgación proporciona secuencias de anticuerpos encontradas en anticuerpos que se unen a CD25 humana. En particular, la presente divulgación proporciona secuencias de anticuerpos anti-CD25 humanos, que no bloquean la unión de CD25 a IL-2 ni la señalización de IL-2. Los anticuerpos y las porciones de unión a antígeno de los mismos que incluyen dichas secuencias se pueden usar en composiciones farmacéuticas y métodos de tratamiento, en particular para tratar el cáncer.
MX2020008768A 2018-03-13 2019-03-13 Agentes anticuerpos anti-cd25. MX2020008768A (es)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201862642218P 2018-03-13 2018-03-13
US201862642243P 2018-03-13 2018-03-13
US201862642230P 2018-03-13 2018-03-13
US201862642232P 2018-03-13 2018-03-13
US201862642248P 2018-03-13 2018-03-13
GBGB1804028.7A GB201804028D0 (en) 2018-03-13 2018-03-13 Anti-CD25 antibody agents
GBGB1804029.5A GB201804029D0 (en) 2018-03-13 2018-03-13 Anti-CD25 antibody agents
GBGB1804027.9A GB201804027D0 (en) 2018-03-13 2018-03-13 Anti-CD25 antibody agents
PCT/EP2018/056312 WO2018167104A1 (en) 2017-03-17 2018-03-13 Fc-optimized anti-cd25 for tumour specific cell depletion
PCT/EP2019/056248 WO2019175216A1 (en) 2018-03-13 2019-03-13 Anti-cd25 for tumour specific cell depletion

Publications (1)

Publication Number Publication Date
MX2020008768A true MX2020008768A (es) 2020-10-08

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Application Number Title Priority Date Filing Date
MX2020008769A MX2020008769A (es) 2018-03-13 2019-03-13 Agentes anticuerpos anti-cd25.
MX2020008768A MX2020008768A (es) 2018-03-13 2019-03-13 Agentes anticuerpos anti-cd25.
MX2020008770A MX2020008770A (es) 2018-03-13 2019-03-13 Agentes anticuerpos anti-cd25.

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MX2020008769A MX2020008769A (es) 2018-03-13 2019-03-13 Agentes anticuerpos anti-cd25.

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MX2020008770A MX2020008770A (es) 2018-03-13 2019-03-13 Agentes anticuerpos anti-cd25.

Country Status (9)

Country Link
US (1) US20240309101A1 (es)
CL (4) CL2020002339A1 (es)
CO (3) CO2020009476A2 (es)
IL (3) IL276995A (es)
MA (2) MA51997A (es)
MX (3) MX2020008769A (es)
PH (3) PH12020551453A1 (es)
RU (2) RU2020128108A (es)
ZA (1) ZA202004771B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11879014B2 (en) 2017-03-17 2024-01-23 Tusk Therapeutics Ltd. Method of treating cancer or depleting regulatory T cells in a subject by administering a human IGG1 anti-CD25 antibody
EP3765502B1 (en) 2018-03-13 2024-08-07 Tusk Therapeutics Ltd Anti-cd25 for tumour specific cell depletion

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IL276997A (en) 2020-10-29
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MA51997A (fr) 2021-06-23
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CL2020002338A1 (es) 2021-04-23
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CL2020002340A1 (es) 2021-04-23
PH12020551451A1 (en) 2021-11-22
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IL276995A (en) 2020-10-29
MA51992A (fr) 2021-06-23

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