CO2019013786A2 - Métodos y composiciones para reducir la inmunogenicidad de los receptores notch quiméricos - Google Patents

Métodos y composiciones para reducir la inmunogenicidad de los receptores notch quiméricos

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Publication number
CO2019013786A2
CO2019013786A2 CONC2019/0013786A CO2019013786A CO2019013786A2 CO 2019013786 A2 CO2019013786 A2 CO 2019013786A2 CO 2019013786 A CO2019013786 A CO 2019013786A CO 2019013786 A2 CO2019013786 A2 CO 2019013786A2
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Colombia
Prior art keywords
immunogenicity
compositions
methods
notch receptors
chimeric notch
Prior art date
Application number
CONC2019/0013786A
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English (en)
Inventor
Peter Emtage
Amy Gilbert
Vladimir Slepushkin
Anselm Levskaya
Spencer Scott
Original Assignee
Cell Design Labs Inc
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Publication date
Application filed by Cell Design Labs Inc filed Critical Cell Design Labs Inc
Publication of CO2019013786A2 publication Critical patent/CO2019013786A2/es

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Abstract

La presente invención se refiere a métodos y composiciones para reducir la inmunogenicidad de receptores Notch quiméricos, y específicamente a factores de transcripción útiles para controlar la expresión génica administrada a los tejidos por dichos receptores Notch quiméricos.
CONC2019/0013786A 2017-06-19 2019-12-09 Métodos y composiciones para reducir la inmunogenicidad de los receptores notch quiméricos CO2019013786A2 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762603993P 2017-06-19 2017-06-19
US201762556765P 2017-09-11 2017-09-11
PCT/US2018/038218 WO2018236825A1 (en) 2017-06-19 2018-06-19 METHODS AND COMPOSITIONS FOR REDUCING THE IMMUNOGENICITY OF CHIMERIC NOTCH RECEPTORS

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Publication Number Publication Date
CO2019013786A2 true CO2019013786A2 (es) 2020-01-17

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US (3) US11325957B2 (es)
EP (1) EP3641791A1 (es)
JP (2) JP7106581B2 (es)
KR (4) KR102489939B1 (es)
CN (1) CN110753552B (es)
AU (2) AU2018289383B2 (es)
BR (1) BR112019026309A2 (es)
CA (1) CA3065549C (es)
CO (1) CO2019013786A2 (es)
IL (1) IL271144A (es)
MX (1) MX2019015513A (es)
NZ (1) NZ759712A (es)
SA (1) SA519410835B1 (es)
SG (1) SG11201911639TA (es)
TW (1) TWI826379B (es)
WO (1) WO2018236825A1 (es)

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CN112243442A (zh) * 2018-04-10 2021-01-19 桑昆血液供给基金会 嵌合Notch受体
CN111826398A (zh) * 2019-04-16 2020-10-27 常州费洛斯药业科技有限公司 用于活细胞间膜蛋白展示和相互作用检测的工程质粒系统
WO2021061856A1 (en) * 2019-09-24 2021-04-01 The Regents Of The University Of California Receptors with heterologous transmembrane domain
EP4267623A1 (en) 2020-12-24 2023-11-01 Kite Pharma, Inc. Prostate cancer chimeric antigen receptors

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