CO2019005540A2 - Modified isolates of streptomyces fungicidicus and its use - Google Patents

Modified isolates of streptomyces fungicidicus and its use

Info

Publication number
CO2019005540A2
CO2019005540A2 CONC2019/0005540A CO2019005540A CO2019005540A2 CO 2019005540 A2 CO2019005540 A2 CO 2019005540A2 CO 2019005540 A CO2019005540 A CO 2019005540A CO 2019005540 A2 CO2019005540 A2 CO 2019005540A2
Authority
CO
Colombia
Prior art keywords
isolates
modified
streptomyces
streptomyces fungicidicus
enduracidine
Prior art date
Application number
CONC2019/0005540A
Other languages
Spanish (es)
Inventor
T Mark Zabriskie
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Publication of CO2019005540A2 publication Critical patent/CO2019005540A2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a aislados modificados de Streptomyces fungicidicu, a composiciones que comprenden estos aislados, y métodos para usar tales aislados y composiciones para sintetizar biológicamente la enduracidina (enramicina). Además, la presente invención se refiere a aislados modificados de Streptomyces fungicidicus que sintetizan biológicamente la enduracidina y facilitan la producción de enramicina de una manera más eficiente.The present invention relates to modified isolates of Streptomyces fungicidicu, compositions comprising these isolates, and methods for using such isolates and compositions for biologically synthesizing enduracidine (enramycin). In addition, the present invention relates to modified isolates of Streptomyces fungicidicus that biologically synthesize enduracidine and facilitate the production of enramycin in a more efficient manner.

CONC2019/0005540A 2016-12-06 2019-05-28 Modified isolates of streptomyces fungicidicus and its use CO2019005540A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662430455P 2016-12-06 2016-12-06
PCT/EP2017/073771 WO2018103905A1 (en) 2016-12-06 2017-09-20 Modified streptomyces fungicidicus isolates and their use

Publications (1)

Publication Number Publication Date
CO2019005540A2 true CO2019005540A2 (en) 2019-05-31

Family

ID=60043150

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2019/0005540A CO2019005540A2 (en) 2016-12-06 2019-05-28 Modified isolates of streptomyces fungicidicus and its use

Country Status (11)

Country Link
JP (2) JP2020500509A (en)
CN (1) CN110072881A (en)
BR (1) BR112019011603A2 (en)
CO (1) CO2019005540A2 (en)
MX (1) MX2019006586A (en)
MY (1) MY194438A (en)
PE (1) PE20190967A1 (en)
PH (1) PH12019501225A1 (en)
TW (1) TWI770070B (en)
UA (1) UA127451C2 (en)
WO (1) WO2018103905A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112019011378A2 (en) 2016-12-06 2019-10-15 Univ Oregon State compositions and methods for the potentiated production of enduracidin in a genetically modified streptomyces fungicidicus strain
CN115261258A (en) * 2022-06-07 2022-11-01 四川汇邦环保科技有限公司 Microbial agent for degrading duramycin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617881C2 (en) * 1965-10-13 1984-07-05 Takeda Chemical Industries, Ltd., Osaka Antibiotic enduracidin and its manufacture
AT269354B (en) * 1965-10-13 1969-03-10 Takeda Chemical Industries Ltd Process for the production of a new antibiotic
US3577530A (en) 1969-07-24 1971-05-04 Squibb & Sons Inc Janiemycin
JPS6038120B2 (en) 1980-10-31 1985-08-30 武田薬品工業株式会社 Production method of the antibiotic enzyuracydin
US8188245B2 (en) 2006-09-29 2012-05-29 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Enduracidin biosynthetic gene cluster from streptomyces fungicidicus
CN101974469B (en) * 2010-10-22 2012-05-23 安徽丰原发酵技术工程研究有限公司 Streptomyces fungicidious mutant strain and application thereof
CN103374537B (en) * 2012-04-25 2015-01-07 牡丹江佰佳信生物科技有限公司 Method for preparing enduracidin and strain produced thereby
CN102864114B (en) * 2012-10-19 2013-11-06 河北圣雪大成制药有限责任公司 Strain for highly yielding enramycin, and preparation method and application thereof
CN103740612A (en) * 2013-12-19 2014-04-23 河北圣雪大成制药有限责任公司 High-yield enramycin strain and screening method thereof

Also Published As

Publication number Publication date
PE20190967A1 (en) 2019-07-08
UA127451C2 (en) 2023-08-30
TWI770070B (en) 2022-07-11
TW201827590A (en) 2018-08-01
MX2019006586A (en) 2019-08-22
PH12019501225A1 (en) 2019-09-23
RU2019117260A (en) 2021-01-11
JP2020500509A (en) 2020-01-16
CN110072881A (en) 2019-07-30
RU2019117260A3 (en) 2021-01-29
JP2023012549A (en) 2023-01-25
BR112019011603A2 (en) 2020-08-18
MY194438A (en) 2022-11-30
WO2018103905A1 (en) 2018-06-14

Similar Documents

Publication Publication Date Title
CO2020015156A2 (en) Rip1 Inhibitor Compounds and Methods for Making and Using The Same Cross Reference to a Related Application
PH12019502283A1 (en) Anti-lag3 antibodies
BR112019012343A2 (en) il-11ra antibodies
CO2020001220A2 (en) Compounds, compositions and methods
BR112018073384A2 (en) modulating polynucleotides
BR112019012342A2 (en) il-11 antibodies
TN2018000276A1 (en) Inhibitors of receptor-interacting protein kinase 1.
CU20190006A7 (en) COMPOSITIONS TO INHIBIT MASP-3
CL2018001722A1 (en) New anti-mfi2 antibodies and methods of use (divisional application 201700506)
TR2021016542A2 (en) Plasma-based films and methods for making and using the same
BR112017003414A2 (en) compositions comprising casein and methods for producing the same
CL2018003087A1 (en) Synthesis of indazoles.
BR112017013661A8 (en) Anthracycline-derived conjugate (pnu), drug-binding protein conjugate (bpdc), method for producing a drug-binding protein conjugate (bpdc), use of a binding protein-drug conjugate (bpdc) and pharmaceutical composition
EA201692526A1 (en) SUBSTITUTED [1,2,4] TRIAZOLE COMPOUNDS
MX2020006612A (en) Compound functioning as bromodomain protein inhibitor, and composition.
EA202090296A1 (en) SPIROCYCLIC COMPOUNDS AND METHODS FOR THEIR PREPARATION AND APPLICATION
CY1120759T1 (en) PREPARATION OF DIGLYCOSITE (S, S) -SECOCOSOLARICIRESINOL AND DIGLYCOSITE (R, R) -SECOSOSOLARICIRESINOL
EA201591712A1 (en) ANTIBIOTIC COMPOSITIONS BASED ON CEFTOLOSAN
EA201591451A1 (en) FLAP MODULATORS
EA201892500A1 (en) APPLICATION OF THE LIGNIN FRACTION AS AN ANTIFYTOPATOGENIC AGENT AND CONTAINING ITS ANTIFYTOPATOGENIC COMPOSITIONS
MX2020002123A (en) Ribociclib salts and solid state forms thereof.
EA202090312A1 (en) SPIROCYCLIC COMPOUNDS AND METHODS FOR THEIR PREPARATION AND APPLICATION
PH12020550703A1 (en) Sulfonamide compounds and use thereof
MX2018005785A (en) Anti-cd22 antibody-maytansine conjugates and methods of use thereof.
PH12017502277A1 (en) Multi-specific binding proteins