CN2876761Y - Thin cell specimen preparing machine - Google Patents

Thin cell specimen preparing machine Download PDF

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Publication number
CN2876761Y
CN2876761Y CN 200620056977 CN200620056977U CN2876761Y CN 2876761 Y CN2876761 Y CN 2876761Y CN 200620056977 CN200620056977 CN 200620056977 CN 200620056977 U CN200620056977 U CN 200620056977U CN 2876761 Y CN2876761 Y CN 2876761Y
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cell
motor
frame
slide
glass carrier
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Expired - Fee Related
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CN 200620056977
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Chinese (zh)
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吴勇
刘志宇
李京考
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李京考
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Abstract

The utility model discloses a thin cell specimen preparing machine consisting mainly of a specimen bottle fixed seat as well as its rotation device 1, a cell metastasis device 2, a cell adsorption-separation device 3, a lifting device 4, a frame 5, an upload glass table 6 and a download glass table 7. A cell stationary liquid bottle seat 8 is arranged on the lower part of the download glass table. The cell adsorption-separation device 3 is respectively connected with an inspiratory cylinder 32, a gas blowing cylinder 33, a waste bottle 34 through an inspiratory pipe 31, a gas blowing pipe 35 and a waste pipe 36 arranged on a cell filter fixed seat 21. The lifting device 4 consists mainly of a lifting plate 41, a linear bearing 42, a slide bar 43, a screw 44, a motor 45 and a deployable mast 46. The linear bearing 42 is arranged on the slide bar 43 and fixed together with the lifting plate 41. The motor 45 is connected with the lower part of the slide bar 43 and fixed on the frame 5. The machine is simple in structure, low in cost and reliable in operation, and can realize automation in the whole making process.

Description

A kind of thin-layer cell pelleter
Technical field
The utility model belongs to the technical field of medical plant equipment, relates to a kind of thin-layer cell pelleter that is used to make cell smear.
Background technology
Traditional cervical cell film-making can not be removed impurity in the sample, mucus, blood etc. effectively, causes that the smear cell accumulation is overlapping, blurred background, cellular morphology is unclear even distortion, and influence is diagnosis correctly.Still residual cell more than 80% such as employed Uterine neck bush, scraper plate or cotton swab can not be transferred to slide and be dropped, and therefore, traditional cervical cell plate coating checking has higher false negative (5%-60%) and false positive.
Cell smear through fixing dyeing is difficult to realize dynamic concept sheet effect.Dyeing course is because the flushing and the immersion of chemicals repeatedly, can not keep full detail, the especially bacterium of former smear preparation and microorganism is lost and morphology destroys, and influence is correctly diagnosed.
Summary of the invention
In order to overcome the deficiencies in the prior art, the utility model provides a kind of thin-layer cell pelleter, it can effectively disperse the cell mass in the sample, isolates the impurity in the sample, make background clear, have high diagnostic significance and meet the thin-layer cell smear of medical standard.This machine compact conformation, with low cost, energy savings, running is accurately reliable.
The technical scheme that its technical matters that solves the utility model adopts is: this thin-layer cell pelleter comprises specimen bottle holder and whirligig, cell transfer device, cell absorb and the separation facility, jacking gear and frame; Specimen bottle holder and whirligig thereof are made up of specimen bottle holder, bearing seat, bearing support, motor and specimen bottle, the specimen bottle holder is fixed on the frame by bearing seat, the below of specimen bottle holder is connected with motor, and motor is fixed on the frame by bearing support; Cell transfer device mainly is made up of cell filter, cell filter holder, invertible head, and cell filter is made up of cell filtration film and cell filtration film round tube frame, and invertible head is connected with motor, and motor is fixed on the extending arm of jacking gear; Upper glass carrier bench and following glass carrier bench are installed on the described frame, on the frame of upper glass carrier bench below cell fixation liquid bottle seat are installed; Described cell absorb and the separation facility mainly is that three conduits by cell filter holder bottom are connected with the refuse bottle with air-breathing cylinder, air blowing cylinder respectively and form; Described jacking gear mainly is made up of lifter plate, linear bearing, slide bar, screw rod, motor and extending arm, linear bearing be installed on the slide bar and and lifter plate be fixed together, motor is connected the below of screw rod and is fixed on the frame.
Described upper glass carrier bench mainly is made up of slide folder, the reservation of slide clamping and motor, and following glass carrier bench mainly is made up of slide folder, the reservation of slide clamping and motor.
The axial line of described cell filter holder does not overlap with the axial line of specimen bottle holder, constitutes an eccentric position.
The air-breathing cylinder and the air blowing cylinder of described jacking gear are fixed on the frame, and the piston rod of air-breathing cylinder directly is connected with the front end of lifter plate, and the piston rod of air blowing cylinder is connected with the rear end of lifter plate by connecting spring.
On the slide folder of described upper and lower glass carrier bench unlatching, the blocking device that can make the slide self-unloading is installed all, unlatching, the blocking device that can make the cell filter self-unloading also is installed on the described cell filter holder.
The utlity model has following technique effect: the utility model only need rotate specimen bottle, the liquid in the specimen bottle and the pipe wall of cell filter produce high velocity impact, because cell filter holder and specimen bottle holder vertical centre axis have designed eccentric position, strengthened eddy current extruding beating action, mucus and cell mass are disperseed rapidly.The utility model only needs a motor, just can drive the jacking gear motion, simultaneously, drives two movement cylinders, also drives invertible head and moves between upper and lower glass carrier bench, makes cell absorption, shifts, separates functions such as draining one gas Ah Chengs.So compact to design, simple structure, with low cost, reliable can realize operating the robotization of overall process.
Description of drawings
Fig. 1 is a structural representation of the present utility model;
Fig. 2 is the structural representation of cell absorb and the separation facility;
Fig. 3 is the structural representation of specimen bottle holder and whirligig thereof.
1. specimen bottle holder and whirligigs thereof among the figure, 10. specimen bottle holder, 11. bearing seats, 12. bearing support, 13. motors, 14. specimen bottles, 2. cell transfer device, 20. cell filters, 201. cell filtration films, 202. cell filtration film round tube frame, 21. cell filter holders, 22. invertible heads, 3. cell absorb and the separation facility, 31. air intake ducts, 32. air-breathing cylinders, 33. the air blowing cylinder, 34. refuse bottles, 35. gas blow pipes, 36. sewer pipe, 4. jacking gear, 41. lifter plates, 42. linear bearing, 43. slide bars, 44. screw rods, 45. motor, 46. extending arms, 5. frame, 6. upper glass carrier bench, 61. slides folder, 62. slide clamping reservation, 63. motor 7. descends glass carrier bench, 71. slides folder, 72. the reservation of slide clamping, 73. motors, 8. cell fixation liquid bottle seat.
Embodiment
Below in conjunction with drawings and Examples the utility model is further specified.
As shown in Figure 1, 2, 3, the utility model mainly is made up of specimen bottle holder and whirligig 1, cell transfer device 2, cell absorb and the separation facility 3, jacking gear 4, frame 5, upper glass carrier bench 6, following glass carrier bench 7 and cell fixation liquid bottle seat 8.
Specimen bottle holder and whirligig 1 thereof are made up of specimen bottle holder 10, bearing seat 11, bearing support 12, motor 13 and specimen bottle 14, specimen bottle holder 10 is fixed on the frame 5 by bearing seat 11, the below of specimen bottle holder 10 is connected with motor 13, and motor 13 is fixed on the frame 5 by bearing support 12.
Cell transfer device 2 mainly is made up of cell filter 20, cell filter holder 21, invertible head 22, cell filter 20 is made up of cell filtration film 201 and cell filtration film round tube frame 202, invertible head 22 is connected with motor 23, and motor 23 is fixed on the extending arm 46 of jacking gear 4.Unlatching, the blocking device that can make cell filter 20 self-unloadings are installed on the cell filter holder 21.
Upper and lower glass carrier bench is separately fixed on the frame 5, and upper glass carrier bench 6 mainly is made up of slide folder 61, the reservation 62 of slide clamping and motor 63, and following glass carrier bench 7 mainly is made up of slide folder 71, the reservation 72 of slide clamping and motor 73.On slide folder 61 and the slide folder 71 unlatching, blocking device are installed, can make the slide self-unloading.
Cell absorb and the separation facility 3 mainly is to be connected with refuse bottle 34 with air-breathing cylinder 32, air blowing cylinder 33 respectively by the air intake duct 31 of cell filter holder 21 bottoms, gas blow pipe 35 and sewer pipe 36 to form, air-breathing cylinder 32 and air blowing cylinder 33 are fixed on the frame 5, the piston rod of air-breathing cylinder 32 directly is connected with the front end of lifter plate 41, and the piston rod of air blowing cylinder 33 is connected with the rear end of lifter plate 41 by connecting spring 34.
Described jacking gear 4 mainly is made up of lifter plate 41, linear bearing 42, slide bar 43, screw rod 44, motor 45 and extending arm 46, linear bearing 42 be installed on the slide bar 43 and and lifter plate 41 be fixed together, motor 45 is connected the below of screw rod 43 and is fixed on the frame 5.5 millimeters of the axial line off normals of cell filter holder 21 and specimen bottle holder 10.When the machine operate as normal, it is descending that invertible head 22 drives cell filter 20, and the 5mm place, bottom apart from specimen bottle 14 stops at cell filtration film 202.
It is as follows that this mechanism of use is done the operating process of artificially colored sample.Specimen bottle is placed in the specimen bottle holder, embedded slide, place cell filter in holder to upper glass carrier bench.Turn on the power switch a cell filter fixing seal that is fixed.Invertible head drives cell filter and moves downward, when cell filter face stroke stops during in distance specimen bottle bottom 5mm.This moment, the specimen bottle whirligig drove the specimen bottle high speed rotating, cell filter pipe wall and specimen fluids strong collision, and the eddy current beating action is played in the off-centre of cell filter and specimen bottle design in addition, and the mucus of specimen fluids and cell mass are broken up rapidly.Air-breathing afterwards cylinder is opened, and invertible head drives cell filter and repeatedly moves up and down in specimen fluids.Cell filter cell filtration film is one deck micron order uniform small pores (selecting corresponding filtering membrane according to different samples), when negative pressure is raised to certain value in the cell filter, the cell that area is big more at first is attracted to filter membrane surface, be less cell successively, be filtered less than the material of micropore.When the filtering membrane surface was filled up fully by cell, the cell filter internal pressure surpassed certain value, and invertible head drives cell filter and moves upward, and was reversed after leaving the sample bottleneck, and liquid is discharged in the refuse bottle fully in the cell filter.Meanwhile, upper glass carrier bench is done entad motion, closely pastes mutually with up cell filter filtering membrane, and at this moment, the air blowing cylinder is opened, and forms malleation in the cell filter, and the cell of filter membrane surface is transferred on the slide.Invertible head drives cell filter and moves downward, and when arriving the sample bottleneck, the cell filter holder is removed the fixing seal of pair cell filtrator, and cell filter falls in the specimen bottle, and invertible head resets.In this process, upper glass carrier bench resets, and the slide folder is opened automatically, and slide falls in the immobile liquid bottle.
It is as follows that this mechanism of use is done the operating process of dynamic concept sheet sample.Specimen bottle is placed in the specimen bottle fixator, and glass carrier bench embeds slide downwards, places cell filter in the cell filter holder, turns on the power switch.Cell filter is by cell filter holder fixing seal, and invertible head drives cell filter and moves downward, and cell filter face stroke distances stops when the 5mm of specimen bottle bottom.Meanwhile the specimen bottle whirligig drives the specimen bottle high speed rotating, and by cell filter tube wall and specimen fluids strong collision, the eddy current beating action is played in the off-centre of cell filter and specimen bottle design in addition, and the mucus and the cell mass of specimen fluids are decomposed rapidly.This moment, air-breathing cylinder was opened, and invertible head drives cell filter and repeatedly moves up and down in specimen fluids.Cell filter cell filtration film is one deck micron order uniform small pores (selecting corresponding filtering membrane according to different samples), when negative pressure is raised to certain value in the cell filter, the cell that area is big more at first is attracted to filter membrane surface, be less cell successively, be filtered less than the material of micropore.When the filtering membrane surface was filled up fully by cell, the cell filter internal pressure surpassed certain value, and invertible head drives cell filter and moves upward, and was reversed after leaving the sample bottleneck, and liquid is discharged in the refuse bottle fully in the cell filter.Meanwhile, following glass carrier bench drives the slide folder and does entad motion, closely pastes mutually with descending cell filter filtering membrane, and at this moment, the air blowing cylinder is opened, and forms malleation in the cell filter, and the filter membrane surface cell is transferred on the slide.Following microscope carrier drives the slide folder and resets.Invertible head drives cell filter and moves downward, and when arriving the sample bottleneck, the cell filter holder is removed the fixing seal of pair cell filtrator, and cell filter falls in the specimen bottle, and invertible head resets, and following glass carrier bench resets.At this moment, manually add a cover cover glass, extract slide out.
Above-mentioned two making processes can realize robotization fully, thereby avoid artificial factor, also avoid operating personnel's pollution, have guaranteed slice-making quality.

Claims (5)

1, a kind of thin-layer cell pelleter that is used to make cell smear comprises specimen bottle holder and whirligig thereof (1), cell transfer device (2), cell absorb and the separation facility (3), jacking gear (4) and frame (5); Specimen bottle holder and whirligig thereof (1) are made up of specimen bottle holder (10), bearing seat (11), bearing support (12), motor (13) and specimen bottle (14), specimen bottle holder (10) is fixed on the frame (5) by bearing seat (11), the below of specimen bottle holder (10) is connected with motor (13), and motor (13) is fixed on the frame (5) by bearing support (12); Cell transfer device (2) mainly is made up of cell filter (20), cell filter holder (21), invertible head (22), cell filter (20) is made up of cell filtration film (201) and cell filtration film round tube frame (202), invertible head (22) is connected with motor (23), and motor (23) is fixed on the extending arm (46) of jacking gear (4); It is characterized in that: upper glass carrier bench (6) and following glass carrier bench (7) are installed on the described frame (5), on the frame of upper glass carrier bench below cell fixation liquid bottle seat (8) are installed; Described cell absorb and the separation facility (3) mainly is to be connected with refuse bottle (34) with air-breathing cylinder (32), air blowing cylinder (33) respectively by the air intake duct (31) of cell filter holder (21) bottom, gas blow pipe (35) and sewer pipe (36) to form; Described jacking gear (4) mainly is made up of lifter plate (41), linear bearing (42), slide bar (43), screw rod (44), motor (45) and extending arm (46), linear bearing (42) be installed in that slide bar (43) is gone up and and lifter plate (41) be fixed together, be connected the below of screw rod (43) and be fixed on the frame (5).
2, thin-layer cell pelleter according to claim 1, it is characterized in that: described upper glass carrier bench (6) mainly is made up of slide folder (61), slide clamping reservation (62) and motor (63), and following glass carrier bench (7) mainly is made up of slide folder (71), slide clamping reservation (72) and motor (73).
3, thin-layer cell pelleter according to claim 1 and 2 is characterized in that: the axial line of described cell filter holder (21) does not overlap with the axial line of specimen bottle holder (10), constitutes an eccentric position.
4, thin-layer cell pelleter according to claim 1 and 2, it is characterized in that: the air-breathing cylinder (32) of described jacking gear (4) and air blowing cylinder (33) are fixed on the frame (5), the piston rod of air-breathing cylinder (32) directly is connected with the front end of lifter plate (41), and the piston rod of air blowing cylinder (33) is connected with the rear end of lifter plate (41) by connecting spring (34).
5, thin-layer cell pelleter according to claim 1 and 2, it is characterized in that: the described slide of going up upper glass carrier bench (6) and following glass carrier bench (7) presss from both sides unlatching, the blocking device that can make the slide self-unloading is installed, and unlatching, the blocking device that can make cell filter (20) self-unloading also is installed on the described cell filter holder (21).
CN 200620056977 2006-03-27 2006-03-27 Thin cell specimen preparing machine Expired - Fee Related CN2876761Y (en)

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Application Number Priority Date Filing Date Title
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103900874A (en) * 2014-03-20 2014-07-02 南昌光明化验设备有限公司 Device capable of automatically separating samples and bottling and having cleaning function
CN106342789A (en) * 2016-10-13 2017-01-25 深圳韦拓生物科技有限公司 Cell vitrification freezing treatment equipment and method
CN107643201A (en) * 2017-10-31 2018-01-30 麦克奥迪(厦门)医疗诊断系统有限公司 A kind of membrane type cell monolayer pelleter and its flaking method
CN108106922A (en) * 2018-01-31 2018-06-01 迈克医疗电子有限公司 A kind of concentration mixing mechanism
CN108398312A (en) * 2018-03-05 2018-08-14 岳晗禹 A kind of medical pathologies preservation observation device
CN108982179A (en) * 2018-07-25 2018-12-11 湖南省天骑医学新技术股份有限公司 A kind of method and apparatus of fast transfer miillpore filter
CN109030151A (en) * 2018-07-27 2018-12-18 上海皓信生物科技有限公司 Liquid-based flaking method
CN110771600A (en) * 2019-11-25 2020-02-11 深圳科学之门生物工程有限公司 A transfer frame for stem cell cryopreserving

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103900874A (en) * 2014-03-20 2014-07-02 南昌光明化验设备有限公司 Device capable of automatically separating samples and bottling and having cleaning function
CN106342789A (en) * 2016-10-13 2017-01-25 深圳韦拓生物科技有限公司 Cell vitrification freezing treatment equipment and method
CN107643201A (en) * 2017-10-31 2018-01-30 麦克奥迪(厦门)医疗诊断系统有限公司 A kind of membrane type cell monolayer pelleter and its flaking method
CN107643201B (en) * 2017-10-31 2024-04-19 麦克奥迪(厦门)医疗诊断系统有限公司 Film type monolayer cell pelleter and pelleter method thereof
CN108106922A (en) * 2018-01-31 2018-06-01 迈克医疗电子有限公司 A kind of concentration mixing mechanism
CN108398312A (en) * 2018-03-05 2018-08-14 岳晗禹 A kind of medical pathologies preservation observation device
CN108982179A (en) * 2018-07-25 2018-12-11 湖南省天骑医学新技术股份有限公司 A kind of method and apparatus of fast transfer miillpore filter
CN108982179B (en) * 2018-07-25 2023-11-07 湖南省天骑医学新技术股份有限公司 Method and equipment for rapidly transferring microporous filter membrane
CN109030151A (en) * 2018-07-27 2018-12-18 上海皓信生物科技有限公司 Liquid-based flaking method
CN110771600A (en) * 2019-11-25 2020-02-11 深圳科学之门生物工程有限公司 A transfer frame for stem cell cryopreserving

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C17 Cessation of patent right
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Granted publication date: 20070307