CN2696662Y - Incision applicator for postoperation - Google Patents

Incision applicator for postoperation Download PDF

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Publication number
CN2696662Y
CN2696662Y CN 200420041486 CN200420041486U CN2696662Y CN 2696662 Y CN2696662 Y CN 2696662Y CN 200420041486 CN200420041486 CN 200420041486 CN 200420041486 U CN200420041486 U CN 200420041486U CN 2696662 Y CN2696662 Y CN 2696662Y
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China
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plaster
wound
zinc
healing
applied ointment
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CN 200420041486
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Chinese (zh)
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刘大为
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Shaanxi Zhongbang Pharma Tech Co ltd
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Shaanxi Zhongbang Pharma Tech Co ltd
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Abstract

The utility model relates to a medical applicator, in particular to an incision applicator for postoperation. The utility model is characterized in that a non-drying adhesive base layer is connected with water punched fabrics, a water-absorbing cotton core is covered by the water punched fabrics, a permanent magnetic sheet is stuck on the water-absorbing cotton core, and the external surface of the applicator is provided with a piece of protective paper. The upper surface of the water punched fabrics is provided with an anti-sticking moisture-preserving film, and a microelement is arranged on the water punched fabrics. The external surface of the permanent magnetic sheet is provided with a microelement coating of platinum, iron and zinc to accelerate the wound healing. Wherein, the platinum element is 0. 5%-1%, the iron element is 93%-95% and the zinc element is 4%-6%. The microelement is the platinum element. The incision applicator for postoperation is adopted by the operative incision, which has the advantages of excellent moisture-preserving property, fast wound healing, persistent pain-relieving effect, security, no side effect and fast detumescence. The mucosa adhesion of postoperation can be prevented, and no scar is left after healing.

Description

A kind of postoperative wound is applied ointment or plaster
Technical field: this utility model relates to a kind of external applies ointment or plaster, and particularly a kind of postoperative wound is applied ointment or plaster.
Background technology:
Magnetic therapy sheets has analgesic effect, because the analgesic effect immediately of magnetic therapy mainly is the irritability that reduces peripheral nerve.Magnetic therapy has bigger alleviation spasm effect, through clinical observation, can make stomach spasm, ascariasis of biliary tract under the action of a magnetic field, and patients' such as renal colic symptom is eased.This mainly is the result of magnetic field to sphincter, smooth muscle spasmolysis.In addition, when diseases such as treatment stiff neck, the obvious diastole of musculi colli before also can making, it is of flaccid muscles to treat the back, and pain is also alleviated thereupon.But present external is applied ointment or plaster and is had only plaster, and the magnetic that is not used in the postoperative wound healing pastes.
Summary of the invention
The purpose of this utility model provides a kind of postoperative wound and applies ointment or plaster, adopt this applying ointment or plaster on the operative incision, have good moisture preserving, wound healing is fast, analgesic effect lastingly, safely, have no side effect, subside a swelling fast, can prevent not long cicatrix after adhesion of postoperative mucosa and the healing.
The technical solution of the utility model is: design a kind of postoperative wound and apply ointment or plaster, it is characterized in that: be connected with spun laced fabric in adhesive sticker basic unit, be surrounded by the suction cotton core in the spun laced fabric, post the permanent magnetism sheet on the suction cotton core, the outer surface of applying ointment or plaster has protection sheet.
Described spun laced fabric upper surface has antiseized moisture film.
On the described spun laced fabric trace element is arranged.
Described permanent magnetism sheet outer surface has copper, ferrum, the zinc microelement coating that promotes wound healing, and wherein copper accounts for 0.5%-1%; Ferrum element accounts for 93%-95%; Zinc element accounts for 4%-6%.
Described trace element is a copper.
Described trace element is a ferrum element.
Described trace element is a zinc element.
In the described dressing moisture film is arranged.
Spun laced fabric both sides in the described adhesive sticker basic unit are connected with protection sheet respectively.
Trace element in the described dressing is that the fineness crossed through nanotechnology treatments is at 120 orders-200 purpose trace element.
This utility model characteristics are: wound healing is the biological process of a complexity.The different mechanical factors acts on operation and the wound surface that different tissues causes and varies in size, and wound healing process is difference to some extent.Operative incision behind thorough debridement and suturing, Level of organization involutory good, wound healing is smooth, scar tissue seldom person is primary healing.Tissue defect is bigger, and slough is more or with infection, needing granulation tissue to fill up wound surface can healing person be secondary healing.The agglutination of operative incision roughly is divided into three phases, and they both had any different, and interknits juxtaposition again.Phase I is inflammatory reaction phase (being stage of preparation), exudate solidifies in wound, fibrin and fibronectin are bonding with wound, platelet, neutrophilic granulocyte, mononuclear cell, fibroblast and blood capillary enter in the wound in succession, justacrine plurality of enzymes and somatomedin start agglutination.Generally in 48 hours, the existing epithelium in the surface of whole wound covers.This phase lays a good foundation for healing, but wound tissue tension intensity is very low in initial 2-3 days.Phase III is a proliferative phase, and postoperative 4-5 days granulation tissue (fibroblast, blood capillary system and substrate) active proliferation collagen stroma occurs, and increases sharply in the wound, and tissue tension intensity raises rapidly, and the peak of general hyperplasia is 2 weeks approximately after surgery.Phase III is the period of maturation, postoperative about January hyperplasia and tissue tension growth rate slow down, cell number and vascularization reduce.After 60-80 days in the wound total collagen quantity reach normal value, and the synthetic of collagen still proceeded with decomposing, the cicatrix refigure, scanning electron microscope confirms that cicatrix fiber figure is in slow change in the several months.In wound healing process, microcirculatory perfusion well is a prerequisite with organizing oxygen supply, and macrophage, platelet and fibroblast play a crucial role.And the magnetic field that the permanent magnetism sheet produces has blood circulation promoting, the absorption that can quicken exudate is dissipated, removed the stimulation of inflammation swelling to nerve, observed by the microcirculation of many cases being sprained patient, the treatment metarteriole vein stasis of blood stagnates, slow blood flow, the part serious symptom has capillary break-up to go out clot, all case blood flow quickenings after the magnetic therapy, and the vein end stasis of blood stagnates and dissolves gradually, wherein most patients cure the back check and all recover normal, and the microcirculatory effect that has clear improvement is described.
Trace element effect in the dressing is as follows:
1, the synthetic and Cu of collagen 2+Relation: the tropocollagen molecules that three peptide chains are formed, its tensile strength of initial period be a little less than.As time passes, between three peptide chains or neighboring molecule form covalent bond, tensile strength just is increased.Though between the intramolecularly of collagen fiber and the molecule character of covalent bond also under study for action, some key internal reaction is determined, as the interconnection of lysine between two peptide bonds.Lysine changes aldehyde earlier into, and the aldehyde radical on two peptide chains reacts and links up then.Under the catalysis of lysyl amino oxidase lysine become-need Cu in the reaction of semialdehyde-a amine adipic acid 2+Be cofactor.The exhaustion of copper or the not enough formation and the crosslinked connection that will influence aldehyde.
2, the synthetic and Fe of collagen 2+Relation with ascorbic acid: also have characteristics during collagen is synthetic, be that proline or lysine are not that first hydroxyl turns to resynthesis collagen after hydroxyproline or the hydroxylysine, but proline or lysine participates in after the synthetic procollagen, makes proline hydroxylating on the peptide chain by the peptidyl-prolyl hydroxylase again.In the hydroxylating process, the oxygen atom in the hydroxyl is from airborne molecular oxygen.The peptidyl-prolyl hydroxylase is substrate and Fe except that needing a-copper 1,3-propanedicarboxylic acid 2+Outside cofactor, also need ascorbic acid as electron donor.So ferrum and ascorbic acid are the necessary materials of wound healing.The general otch that does not infect, postoperative 7d left and right sides collagen forms, and can make patient be engaged in general unlikely the splitting of movable otch, and can take out stitches and leave hospital this moment.But the formation of wound collagen and crosslinked sustainable several months or for many years, this period still needs constantly to replenish ascorbic acid.If lack ascorbic acid, vitamin C deficiency can appear in patient, and otch still has the possibility of splitting under external force.
3, the relation of wound healing and zinc: zinc is the coenzyme of many enzymes in the body or the composition of prothetic group, and extensive influence body internal protein, fat and sugar metabolism.Particularly zinc is the coenzyme composition of archaeal dna polymerase and RNA polymerase, with the division and the proteinic synthetic substantial connection that all has of cell.With closely-related proteoglycan of wound healing and collagen fiber, on chemical constituent, all belong to protide, so zinc also influences the synthetic of them.Moreover, zinc is more remarkable to the influence that the wound epithelium covers, and this influences cell division and growth from zinc, influences proteinic synthetic, and 20% zinc is present in the skin in the body, especially concentrates on epithelial tissue (zinc content is up to 120~250 μ g/g) and can obtain explaining.Many scholar's research affirm that body is in when hanging down the zinc state, and zinc supplement has facilitation to wound healing.And stress the time (as operation) discharge and increase along with urinary nitrogen, urine phosphorus, urine sulfur etc., urine zinc is discharged and is also increased.Because of zincode easily combines with some low-molecular-weight chemical compounds such as aminoacid, beta-hydroxybutyric acid etc. in the blood plasma, filtered and discharge by kidney, so when albumen was lost from urinate, zinc was also lost thereupon.Urine zinc is lost the degree that descends with blood plasma zinc and the length of persistent period with the character of wound and the order of severity and different.So operation back body more or less is in low zinc state for some time, as is replenished then and can be promoted the epithelium wound healing.If zinc supplement before the operation although postoperative still has blood zinc to reduce, can keep normal level.Come zinc supplement with zinc sulfate or zinc acetate clinically.Food aspect, animal skin zinc content are all very high, when as a supplement during the source of glycine, proline, also having obtained the zinc of volume with Corii Sus domestica or Ungula Sus domestica simultaneously.
The utlity model has following effect in a word:
1, has good moisture preserving, be beneficial to wound healing.
2, good permeability can guarantee the eupnea of skin.
3, the exudation effect is strong, is beneficial to tissue repair.
4, analgesic effect lastingly, safely, have no side effect.
5, detumescence is fast, than common dressing fast about 3 days.
6, antiinflammatory can be avoided infection of incisional wound, be alleviated patient's burden.
7, can prevent the adhesion of postoperative mucosa.
8, can shorten healing time.
9, finished the cicatrix time of moulding again in advance in 5 months, and not long cicatrix after the healing.
10,1/3 time finished in advance can to make healing time.
11, subcutaneous nothing scleroma phenomenon, the tissue blood circulation is good.
12, sticking wound is removed when changing dressings the back destruction to new granulation tissue from.
13, can make the ulcer wound healing, alleviate patient's misery.
14, the wound after the healing, the sensation of depletion of YIN it rains sufferings has been removed patient's sequela from.
15, contained trace element is copper, ferrum, zinc in the dressing, and these trace element have facilitation to wound healing, is that wound healing is requisite.
16, the moisture film in the dressing keeps the wound surface moist environment, and the damaged tissues wound surface is created a moist environment, because the autolysis of moistening wound surface, its healing can be simplified debridement, promotes the cleaning of wound.Because the wound surface exudate is a ring of whole agglutination, exudate contains a great deal of to the indispensable somatomedin of wound healing process, and its kind and quantity play important regulating action to wound healing; Its function comprises stimulates fibroblast proliferation as macrophage, all many-sides such as chemical chemoattractant of neutrophilic granulocyte and smooth muscle cell.Moist environment helps the wound healing performance: (1) protection granulation granule; (2) the inflammation diffusion is disappeared; (3) wound pain alleviates; (4) exudate reduces; (5) fibrin film appears; (6) growth of wound surface microbial bacterial is suppressed, and pathogen disappears; (7) wound re-epithelialization ability improves.
One, accelerates healing speed, minimizing cicatrization.
Wound healing time, Dditch discovers: wound surface 10d healing person, the incidence rate of cicatrix is 0-6%, hinders back 10-14d healing, and incidence rate is 4%-19%, and after the 14-21d healing, sending out the back rate is 30%-35%, and mostly is hypertrophic cicatrix after hindering.Wound 21d is just healing later on, and incidence rate is 60%-80%.This shows healing time to the generation of growth property cicatrix be formed with confidential relation.Of the present utility model applying ointment or plaster compared fast 18-20d to speed of wound healing than the wound of common dressing parcel, compare with biopsy wound healing rate, all healings of two week of wound back of applying ointment or plaster and covering of the present utility model, and healing back cicatrix is slight, and common dressing covers wound, have only 63% healing, and the generation of hypertrophic cicatrix is arranged more.
Two, pain relieving, detumescence, antiinflammatory
The postoperative disorganization, circulatory disturbance, neural destruction exposes, and organizes transudate that the stimulation of otch is caused pain.Of the present utility model apply ointment or plaster cover pain behind the wound and significantly be lighter than the patient that those fine mesh spun laced fabrics cover wounds, particularly postoperative anesthetic action and disappear after, in 72 hours the pain difference very obviously, (p (0.001).Of the present utility model applying ointment or plaster can be loosened 50-100 μ arteriole and be improved the vasomotion of 20-30 μ arteriole, and the permeability that suppresses venule portion is hyperfunction, makes the blood exudate of the state of smouldering recover normal rapidly.Under effect of applying ointment or plaster of the present utility model, blood can bring out a kind of Joule heat in body circulation time, impels telangiectasis, and blood flow is accelerated, so reach analgesic effect.And then suppress histamine, 5-hydroxy tryptamine, the slow stimulation that swashs chemical substances such as titanium to teleneuron.Eliminating postoperative edema is postoperative human body spontaneous recovery process, of the present utility model apply ointment or plaster to have to stop ooze out and sorbefacient dual function, the hematoma area is littler by about 50% than common dressing after 3 days, regression time fast 60%; This is that blood flow rate has due to the optimum effect because of of the present utility model applying ointment or plaster to microvascular permeability, colloid osmotic pressure.Of the present utility modelly apply ointment or plaster better, bacterium property inflammation is had better curative effect too the aseptic inflammation curative effect.Because of leukocyte under the action of a magnetic field, phagocytic function obviously strengthens, neutrophilic granulocyte accounts for 70% of total white blood cells, neutrophilic granulocyte has to be engulfed and germ-resistant function, in body, play important defense reaction, the inflammation of wound healing is a feature with the quick gathering of neutrophilic granulocyte to the injury promptly in early days, and it mainly act as infection.
The analgesic test
(1) experimental technique
1,50 ♂ ♀ half and half of SD kind rat, body weight 167.7 ± 16.4g is divided into 5 groups at random, and 3 the dosage groups of applying ointment or plaster of the present utility model with this utility model design are respectively 2000Gs, 1800Gs, 1500Gs; 30 rat backs cut off 4 * 1.5cm dorsal body setae, by operation specification handles sterilization, cut-3cm is long, and the degree of depth is the 3mm edge of a knife, sews up two pins, the applying ointment or plaster of the utility model that loses money in a business.Dolantin is as positive controls, and dosage is 50mg/kg, and 10 rat the north cut off 4 * 1.5cm dorsal body setae, by the sterilization of operation specification handles, cuts-3cm, and the degree of depth is the 3mm edge of a knife, sews up two pins, and common sterilization spun laced fabric dressing is handled, experiment back 15min intraperitoneal administration; With the negative matched group of normal saline, dosage is 10ml/kg, and 30min filling stomach gives before the experiment.
2, the wound analgesic experiment is adopted in this experiment, measures the pain threshold of a rat.
Experimental result:
Group Number of animals (only) Pain threshold (s) X ± s
The dolantin group 10 59.7±0.7
The normal saline group 10 10.9±1.6
Permanent magnetism is applied ointment or plaster 2000GS 10 48.8±3.1
1800GS 10 45.2±4.2
1500GS 10 42.5±4.6
Compare with the normal saline group * *P<0.01
Experiment conclusion: under this experiment condition, 3 the dosage groups of applying ointment or plaster of the present utility model all have significant analgesia role.
Microcirculation experimental technique and result:
50 of SD kind rats, body weight 167.1 ± 16.3g, ♂ ♀ half and half, random packet, the utility model that loses money in a business be applied to rat ears root, normal saline and intramuscular injection phentolamine.Applying ointment or plaster of the utility model that loses money in a business is preceding earlier with two observation by light microscope mensuration rat ears one blood capillary diameter of marked region, get under the same visual field average of the approaching substantially blood capillary diameter of several calibers, the metarteriole diameter of applying ointment or plaster as the utility model that loses money in a business, each group is pasted the fast obedient 40min of healing and is observed the blood vessel diameter of measuring under the same visual field once more, gets the diameter of its average as the back blood vessel of applying ointment or plaster of the utility model that loses money in a business.Add up the lose money in a business difference of blood capillary diameter before and after the applying ointment or plaster of utility model of each treated animal, handle, the results are shown in following table with the paired t-test method statistic:
Of the present utility model applying ointment or plaster to the influence of rat ears blood capillary
This practicality of group permanent magnetism 2.16 ± 0.20 Dosage (GS) is 2000GS 0.83 ± 0.32 (g/kg) The variation of blood vessel diameter (μ/m) X±sDifference 1.88 ± 0.21 novel applying ointment or plaster before and after using after using before the P value is used
<0.01 0.78±0.29 Permanent magnetism is of the present utility model applies ointment or plaster 1800GS 1.85±0.11 1.98±0.18
<0.01 0.74±0.26 Permanent magnetism is of the present utility model applies ointment or plaster 1500GS 1.78±0.25 1.86±0.19
<0.01 Normal saline 100ml/kg 1.99±0.23 2.05±0.24
0.15±0.34 1.10±0.80 Phentolamine 0.003 2.10±0.38 3.26±1.01
The permanent magnetism acute toxicity testing of applying ointment or plaster of the present utility model with this utility model design
1, totally 8 of Kunming mouses, male and female half and half, age in 8-10 week, body weight 18-22g.
2, preceding 8 mices of experiment are all taken off dorsal body setae, area 3 * 5cm 2
Cut homalographic when 3, testing and apply ointment or plaster, observe mice and have no adverse reaction in three weeks of mouse back.
The result: 8 mices there is no any untoward reaction (21 days).
The permanent magnetism repeatedly skin irritation test subject source of applying ointment or plaster of the present utility model: Shanxi Zhongbang Pharmaceutical Technology Co., Ltd.'s experimental technique: 3 of rabbit, male and female are not limit, the heavy 2.5-3kg of female no conceptus.Test and cut off rabbit spinal column both sides 3 * 3cm dorsal body setae in preceding 24 hours.Left side depilation district is coated with normal saline and does blank, right side region the applying ointment or plaster of utility model that lose money in a business.Continuous once a day 14 times, observe the animal skin reaction.Experimental result: skin perusal and the equal zero difference of histopathologic examination, no abnormality seen are distinguished in 3 rabbit left sides or right depilation.
Experiment conclusion: according to " disinfection technology standard " skin irritation test evaluation criterion repeatedly, this is applied ointment or plaster to the skin nonirritant.
Below in conjunction with the embodiment accompanying drawing this utility model is described further.
Description of drawings:
Fig. 1 is embodiment 1 structural representation.
Fig. 2 is embodiment 1 cutaway view.
Among the figure: 1, adhesive sticker basic unit; 2, antiseized moisture film; 3, adhesive plaster; 4, permanent magnetism sheet; 5, suction cotton core; 6, carat hot paper; 7, spun laced fabric.
The specific embodiment:
Embodiment 1 as shown in Figure 1, mid portion in adhesive sticker basic unit 1 is connected with spun laced fabric 7, be wrapped in suction cotton core 5 in the spun laced fabric 7, post permanent magnetism sheet 4 on the suction cotton core 5, be stained with adhesive plaster 3 on the permanent magnetism sheet 4, the upper surface of spun laced fabric 7 is covered with antiseized moisture film 2, be bonded with a carat hot paper 6 respectively in spun laced fabric 7 both sides of adhesive sticker basic unit 1, cover the dressing surface and shield, be coated with trace element on the permanent magnetism sheet 4, wherein copper accounts for 0.8%; Ferrum element accounts for 94%; Zinc element accounts for 5.2%.Open a carat hot paper 6 during use, on wound, and be adjacent to fixing the dressing paste that is connected with permanent magnetism sheet 4 with the adhesive sticker basic unit 1 of spun laced fabric 7 both sides.Because copper, ferrum, the zinc element of plating emit in the wound under the effect of the magnetic line of force on the permanent magnetism sheet 4, add the effect of magnetic force, quickening cicatrizes a wound.
This product amounts to seven kinds of specifications and sees the following form:
Specification The magnetic sheet number Size Explanation
8×7 1 cm Adhesive tape size 8 * 7
12×10 2 cm Cotton core 12 * 5 adhesive tapes 18 * 10
18×10 3 cm Cotton core 18 * 5 adhesive tapes 22 * 10
22×10 4 cm Cotton core 22 * 5 adhesive tapes 28 * 10
28×10 5 cm Cotton core 28 * 5 adhesive tapes 34 * 10
35×10 6 cm Cotton core 35 * 5 adhesive tapes 41 * 10
42×10 7 cm Cotton core 42 * 5 adhesive tapes 48 * 10
Remarks Except that 8 * 7, all the other 6 kinds of specification illustrated dimension are meant cotton core length * tape width
The clinical experiment result of embodiment 1 is as follows:
Patient's 140 examples at 3~31 years old age, will be divided into two groups with sick patient's random digit method of planting: experimental group, matched group.
The common dressing of matched group patient; After the experimental group patient implemented operation stitching, wound was disinfected by standard and is finished, and was about to dressing of the present utility model and applied on otch by the wound size, and fix, until the doctor's advice nurse that takes out stitches provides special care to, and the patient who makes respective record and matched group makes contrast.
Specifically be grouped as follows:
Experimental group: 80 examples, wherein gynecological's cesarean is routine with embodiment 3 dressing, appendicitis operation 16 example embodiment 4 dressing with dressing 30 examples, orthopaedics 14 example embodiment 1 dressing, the wound suture 20 of embodiment 2.
Matched group: 60 examples, wherein gynecological's cesarean 25 examples, orthopaedics 10 examples, wound suture 15 examples, appendicitis 10 examples of performing the operation.
Evaluation criterion
1. recovery from illness: wound surface does not have redness, no secretions, and the wound healing situation is good, local slight tenderness;
2. produce effects: wound surface is slightly red and swollen, no secretions, and wound healing is good, and there is slight tenderness the part;
3. effective: the local tenderness of wound surface, redness, wound healing is poor slightly, and a little secretions is arranged;
4. invalid: wound surface tenderness, redness, wound healing difference or infection is arranged;
Experiment is done statistical analysis by The Fourth Military Medical University's military medical equipment and meterological teaching and research room after finishing, and adopts SPSS10.0 statistics software kit.
The trial state record
The operation branch The example number The set of applications healing state The example number Contrast back group healing state
Cesarean 30 1. not too feel pain in postoperative 24-72 hour; 2. wound does not have 1 example infection; 3. healing is fast, and cicatrix is slight. 25 1. sharp ache in the postoperative 24 hours, 4 example clothes tablet for alleviating pain, 1 example bucinnazine; 2. wound 2 example infection 3. cicatrixes are obvious.
Orthopaedics 14 1. postoperative had mild pain in 72 hours, and healing time is fast, and cicatrization is little; 2. healing is fast 10 1. 72 hours pain of postoperative all needs analgesic control unbearably.2. cicatrization is obvious; 3.2 example infects.
Department of general surgery 20 1. facial wound is after sewing up, and it is not obvious to use the back cicatrix of taking out stitches in 6-7 days.2. wound does not have the sense of tightening.3. healing is fast, and cicatrix is slight. 15 1. cicatrization is obvious; 2. sense is tightened in the wound; 3. face scar easily causes burden at heart to the patient.
Appendectomy 16 1. do not have cicatrization, 2. do not have 1 example and infect.3. healing is fast, and cicatrix is slight 10 1.2 obvious 1 example of routine cicatrix infects; 2.24 sharp ache in hour.
Conclusion 80 Respond well 60 Generally
1. efficacy analysis
Ranked data two samples relatively adopt non-ginseng Wilcoxon (Mann-Whitney Test) rank test.Ranked data are classified as follows table:
Table 1 patient uses and does not use this utility model dressing curative effect relatively
Do not use and use
Curative effect
Experimental group N (%) matched group N (%)
Invalid 2 (2.50%) 6 (10.00%)
Effective 23 (28.75%) 26 (43.33%)
Produce effects 38 (47.50%) 19 (31.67%)
Recovery from illness 17 (21.25%) 9 (15.00%)
Add up to 60
Assay:
P=0.012<0.05, both can think: the patient uses and does not use the curative effect of applying ointment or plaster of the present utility model that significant difference is arranged.The experimental group total effective rate is 97.50%;
Embodiment 2, its dressing syndeton is identical with embodiment 1, with the difference of embodiment 1 be that it not only is coated with trace element on permanent magnetism sheet 4, and to be evenly distributed with the fineness of crossing through nanotechnology treatments at the dressing upper surface be 200 purpose copper, ferrum, zinc element.Better through the experiment contrast effect than embodiment 1.
To this utility model clinical effective rate analytic induction be following some:
(1), have the effect of activating blood circulation to dissipate blood stasis, clinical trial result is (P<0.01) obviously, curative effect obviously is better than matched group.
(2), can reduce inflammation to ooze out and quicken inflammation absorbs, isotopic labeling finds that the action of a magnetic field can be accelerated protein and shift.Regulate the colloid osmotic pressure gradient in the blood vessel, ooze out, promote wound healing thereby reduce.
(3), granulation tissue forms and epithelial cell takes place not to be obstructed, and shows degeneration or the paraplasm collagen of can selectively degrading under the wound condition of applying ointment or plaster of the present utility model, and normal with newborn collagen is then had the growth of promotion effect.
(4), copper, ferrum, zinc element combines with dressing, complements each other, and has simultaneously to change the silt knot preferably and loose, the convergence granulation promoting suppresses the effect that cicatrization promotes wound repair.
(5), indication wide (P>0.05), do not observed allergy and toxicity or local pain aggravation performance.
(6), when different age of operation patient uses of the present utility model applying ointment or plaster, have a significant difference (P<0.01) between its curative effect, compare with older patient, experimental result shows that between twenty and fifty patient's result of use is better;
Because this applies ointment or plaster and has no side effect, easy to use, use that the back wound healing is fast, subcutaneous tissue does not have scleroma, obtained the approval of doctor and patient during the clinic trial.
2. experimental group operation kind efficacy analysis
Whether the population distribution of inferring a plurality of independent samples of ranked data has difference, with non-ginseng sum of ranks Kruskal-Wallis Test check.Ranked data are classified as follows table:
Table 2 operation kind efficacy analysis
Operation classification N (%)
Outside curative effect gynecological orthopaedics is general
Vermiform appendix
Invalid 1 (3.33%) 1 (7.14%) 0 (0.00%) 0 (0.00%)
Effective 7 (23.33%) 5 (35.71%) 6 (30.00%) 5 (31.25%)
Produce effects 14 (46.67%) 6 (42.86%) 9 (45.00%) 9 (56.25%)
Recovery from illness 8 (26.67%) 2 (14.29%) 5 (25.00%) 2 (12.50%)
Add up to 30 14 20 16

Claims (10)

1, a kind of postoperative wound is applied ointment or plaster, and it is characterized in that: be connected with spun laced fabric in adhesive sticker basic unit, be surrounded by the suction cotton core in the spun laced fabric, post the permanent magnetism sheet on the suction cotton core, the outer surface of applying ointment or plaster has protection sheet.
2, a kind of postoperative wound according to claim 1 is applied ointment or plaster, and it is characterized in that: described spun laced fabric upper surface has antiseized moisture film.
3, a kind of postoperative wound according to claim 1 is applied ointment or plaster, and it is characterized in that: on the described spun laced fabric trace element is arranged.
4, a kind of postoperative wound according to claim 1 is applied ointment or plaster, and it is characterized in that: described permanent magnetism sheet outer surface has copper, ferrum, the zinc microelement coating that promotes wound healing, and wherein copper accounts for 0.5%-1%; Ferrum element accounts for 93%-95%; Zinc element accounts for 4%-6%.
5, a kind of postoperative wound according to claim 1 is applied ointment or plaster, and it is characterized in that: described trace element is a copper.
6, a kind of postoperative wound according to claim 1 is applied ointment or plaster, and it is characterized in that: described trace element is a ferrum element.
7, a kind of postoperative wound according to claim 1 is applied ointment or plaster, and it is characterized in that: described trace element is a zinc element.
8, a kind of postoperative wound according to claim 1 is applied ointment or plaster, and it is characterized in that: in the described dressing moisture film is arranged.
9, a kind of postoperative wound according to claim 1 is applied ointment or plaster, and it is characterized in that: the spun laced fabric both sides in the described adhesive sticker basic unit are connected with protection sheet respectively.
10, a kind of postoperative wound according to claim 1 is applied ointment or plaster, and it is characterized in that: the trace element in the described dressing is that the fineness crossed through nanotechnology treatments is at 120 orders-200 purpose trace element.
CN 200420041486 2004-02-15 2004-02-15 Incision applicator for postoperation Expired - Lifetime CN2696662Y (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107854218A (en) * 2017-12-12 2018-03-30 成都美益达医疗科技有限公司 A kind of disposable hydrocolloid antibacterial application

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107854218A (en) * 2017-12-12 2018-03-30 成都美益达医疗科技有限公司 A kind of disposable hydrocolloid antibacterial application

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