CN2650134Y - Fully-automatic dynamic contamination device - Google Patents
Fully-automatic dynamic contamination device Download PDFInfo
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- CN2650134Y CN2650134Y CN 200320117313 CN200320117313U CN2650134Y CN 2650134 Y CN2650134 Y CN 2650134Y CN 200320117313 CN200320117313 CN 200320117313 CN 200320117313 U CN200320117313 U CN 200320117313U CN 2650134 Y CN2650134 Y CN 2650134Y
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Abstract
The utility model relates to a toxicology testing device, which is mainly used for dynamic inhaling toxicological test of animals for water-soluble or oil-soluble exogenous materials. The device consists of a control system, a toxicological system, an air supply system, a liquid supply system, an exhaust and drainage system; the whole device has large application range, toxicological concentration of 10 to 10000MG/M<3>, safe system, accurate and timely obtained data, easy getting manufacture materials, and is suitable for batch production. The device combines a plurality of modern technologies and discipline theories, thereby filling in the gaps in the fields of homemade automatic toxicology testing.
Description
Affiliated field: the utility model relates to a kind of toxicological experiment device, mainly is applicable to the dynamic suction-type exposure experiment of animal for water-soluble or oil-soluble allogene.
Prior art:
Along with the development of economy and technology, the market demand is maked rapid progress, and new biogenetic products are all arranged every day, and new medicine, health products, cosmetics, new chemical fertilizer, agricultural chemicals or the like come out.And whether these new things are harmful to human body or environment, then must carry out toxicological experiment to it.Very important means of toxicological experiment are animal contaminated experiments, and contamination has per os (feeding), and through skin (smearing), realize through respiratory tract modes such as (suction), the utility model product promptly is one to overlap the device that is specifically designed to animal imbedibility exposure experiment.This device can provide experimental datas such as concentration of contamination, contamination time, temperature, humidity in real time in the environment of circulation of air is arranged, for toxicologic study provides in time, accurate, reliable scientific basis.The current experiments mode, mostly adopt quiet formula to suck or analysis obtains data to air sampling by other analytical instrument such as gas chromatograph,, consumption power consuming time as the method, cost are high, and it is not directly perceived, can not obtain experimental result in real time, and can't control experimentation, can't satisfy the toxicologic study with widespread demand and the experiment demand of application far away.
Technology contents
For addressing the above problem, the toxicological experiment whole experiment is control effectively, real-time collection experimental data provides a kind of safety, is easy to control, and institute's image data is the toxicological experiment device accurately, and the utility model provides following technical scheme:
1, system architecture:
This device mainly is made up of control system, toxicity contaminated system, liquid-supplying system, air supply system and exhaust outlet system.Control system mainly comprises computer system, and single-chip microcomputer and governor circuit are connected by cable between each system of control system and other; The built-in control program of single-chip microcomputer wherein.Begin to carry out initialization during system start-up, according to requirement of experiment input experimental period, (scope is from 10mg/m for concentration of contamination
3-10000mg/m
3), soup proportion etc.; Calculate the ratio of soup and air then according to initial value; Proportionate relationship satisfies following formula:
K: default concentration of contamination (mg/m
3)
N: soup proportion (g/ml)
H: soup flow velocity (ml/min)
L: gas flow rate (l/min)
In system's operational process, whether the ratio that constantly detects liquid supply rate, air demand by circuit satisfies preset value, and the size of constantly regulating air demand and liquid supply rate is till the time finishes.Establish the data-interface of standard between control desk and the computer, experimental data is taken in the computer at any time by interface and analyzes automatically, prints and preserves.
Toxicity contaminated system comprises toxicant exposure cabinet, and toxicant exposure cabinet adopts stainless steel to make, and center section adopts clear glass, is convenient to during experiment observe.Toxicant exposure cabinet inside is provided with airtight circular glass inner bag, and inner bag is the rest area of animal used as test.Inner bag inflow point is provided with atomising head.Inner bag is equipped with temperature, moisture probe, and this probe links to each other with control system.When system moved, the temperature of inner bag and humidity can be passed control system in real time back
Air supply system includes compressor, gas meter, air valve, air supply pipe.Compressor is mainly used in pressurized air, the size of air valve major control gas flow, and gas meter is measured the gas flow rate flow.
Liquid-supplying system comprises medicine pond, fixed displacement pump, lacks medicine warning device and woven hose.The medicine pond is used to deposit treats reagent liquid; Fixed displacement pump adopts the creeping motion type fixed displacement pump of superprecision, and the signal work that fixed displacement pump accepts control console to send is transported to atomising head with soup by woven hose.Lacking the medicine warning device is infrared generation receiving sensor, is responsible for monitoring the soup in the medicine pond.It has used the light refraction principle, it is a pair of infrared generation receiver, be installed in bottom, medicine pond with certain angle, the infrared light that sends when soup is sufficient is refracted and can not be received, when lacking medicine, sensor can receive infrared light, sends a signal this moment, and controller will send scarce medicine warning after receiving this signal.
The air draft unwatering system mainly includes blower fan, airduct, drainpipe.Blower fan guarantee of work inner bag negative pressure prevents that inner bag poison gas from leaking, and guarantees personal safety, and gas in the cabinet is extracted out to be reached for the purpose of inner bag ventilation.Drainpipe is connected with inner bag, discharges animal used as test excreta and cohesion liquid medicine.
2, system works principle:
As shown in Figure 2, its core is single-chip microcomputer and the control program in the control desk 3.The data-interface 2 that standard is arranged between control desk and the computer 1, by this interface, experimental data can be taken in the computer at any time and analyze, and prints and preserves.At first, control program is according to default concentration of contamination, the calculation of parameter liquid medicine of soup proportion and the ratio of tolerance, and send instruction specified rate pump 7 by stube cable 4, start compressor 10, the soup that pumps from medicine pond 5 mixes to atomising head 8 with pressurized air through air supply pipe 13 through woven hose 6, enters 9 li of airtight inner bags that are placed with animal used as test with vaporific form, the work of gas outlet 16 is to guarantee the inner bag air negative pressure, makes the air of inner bag keep circulation.Drainpipe 17 is discharged the excreta of animal and the combination gas that condenses into water.Gas meter 11 feeds back to control desk in real time with gas flow, and control desk is according to this feedback signal, and the amount of infusion of real-time regulated air valve 12 sizes and fixed displacement pump 7 so forms a closed-loop control system, guarantees that the mixture strength that enters into inner bag reaches preset value.The scarce medicine warning device 14 of liquid-supplying system is to send signal to control desk when soup uses up, and control desk gives the alarm after receiving this signal, reminds operating personnel's dosing.Temperature, moisture detector 15 are reported temperature and moisture condition in the inner bag at any time to control desk.
3, systematic functional structrue
From functional structure, whole device is divided into control, execution, experiment, feedback and aftertreatment five parts, as shown in Figure 4.
The core of control section is a computer system, single-chip microcomputer and software program, and the work that it will be finished is the goal-selling of accepting the experimenter, issues instructions to operating part, shows the experimentation data in real time, accepts feedback information and makes corresponding adjustment or warning.
Operating part is the instruction of finishing control console, mainly is meant water pump for soup, and air valve folding size, air feed are also sent soup and gas mixed aerosol into the test block, and the fanman makes to keep the inner bag negative pressure.
Experimental section is the target that this device finally should be realized.It is actually the circular airtight cylinder body of being made by clear glass.Transparent being convenient to observed, and the airtight inner bag combination gas that can guarantee is the poison gas concentration of presetting.
Feedback fraction is to send some necessary datas of experimentation back to control section in real time, its air inclusion flowmeter, thermometer, hygrometer, IR sensor.Gas meter feeds back to controller with gas flow, can adjust tolerance and soup ratio at any time; Temperature, moisture meter report to controller and demonstration with real-time temperature, the humidity of test block; IR sensor is after soup uses up, and sends signal and gives controller.
Aftertreatment partly comprises the discharging (after-treatment device of poison gas, sewage is not contained in this device) of harmful toxic gas, soup.
Advantage of the present utility model
1, advanced technology
This device has been used multinomial modern means of science and technology and each subjects theory, forms through well-designed, has filled up a blank of domestic robotization toxicological experiment.
3, applied widely
Concentration of contamination is from 10-10000mg/m
3, default arbitrarily, can do high poison, every toxicological experiment of poisoning and low toxicity.
4, the data of Shou Jiing accurately and timely
Owing to adopt computer control, can guarantee the blending ratio of soup and gas, thereby guarantee the reliability of experimental result.Experimental data shows in real time in experimentation, and can directly be called by computer and carry out data analysis, printing and preservation.
5, safety
Operator's console separates with cabinet, can allow the operator as far as possible away from venomous injurant, and exhaust system prevents that poison gas from leaking.The toxic and harmful and the liquid of discharging can be through environmental protection treatment, unlikely contaminated environment.
6, can realize
No matter on technology and material, this device all makes things convenient for realization, is convenient to produce in batches, can be widely used in having all departments of toxicological experiment needs.
7, the chemical property of target allogene is constant.The oxygen level of Experimental Area air is consistent with atmosphere.
Six, description of drawings
Figure one is the utility model device for mechanical structural representation
Figure two is the utility model device principle of work synoptic diagram
Figure three is the utility model apparatus control program process flow diagrams
Figure four is the utility model apparatus function structural representations
Wherein:
1 is computer system
2 is data-interface
3 is controller
4 is umbilical cable
5 is the medicine pond
6 is woven hose
7 is the creeping motion type fixed displacement pump
8 is the hydrocone type atomising head
9 is inner bag
10 is air compressor
11 is gas meter
12 is air valve
13 is air supply pipe
14 is IR sensor
15 is temperature, moisture meter
16 is gas exhaust duct
17 is drainage pipeline
18, contamination cabinet
Case study on implementation:
Below in conjunction with accompanying drawing the utility model is implemented to be further described:
Whole device is made up of control system, toxicity contaminated system, air supply system, liquid-supplying system, exhaust outlet system.
As shown in Figure 1, set controller 3 earlier, in controller 3, set the The whole control program in single-chip microcomputer, circuit and the single-chip microcomputer.The whole control system is independently separated with other parts, and links to each other with other each several part by cable 4.Under experiment work on the spot environment condition of severe, the operator can be in the operation that experimentizes away from the scene like this.Simultaneously control system is linked to each other with computer 1 by standard data interface 2, realize real-time analysis, printing.
Adopting stainless steel is that material is made contamination cabinet 18, and the cabinet center section is provided with transparent glass.The core of cabinet is provided with circular glass inner bag 9.Upper top inflow point at inner bag 9 is provided with hydrocone type atomising head 8.Be provided with exhaust system 16 and drainpipe 17 in the bottom of inner bag 9.The conical top of glass inner bag 9 is provided with temperature, the humidity sensor 15 that links to each other with control system.
The bottom of toxicant exposure cabinet is provided with compressor 10, compressor 10 is connected with gas woven hose 13, gas meter 11 is housed on the gas woven hose 6 successively, air valve 12, reach the hydrocone type atomising head 8 at inner bag 9 tops at last, gas meter 11 links to each other with control system by cable 4 simultaneously, regulates the tolerance size by control system control air valve.
Be provided with medicine pond 5 at the cabinet middle part, the bottom, pond is provided with a pair of infrared sensor 14 of accepting.The medicine pond is connected with woven hose 6, and fixed displacement pump 7 is housed on the woven hose 6, and woven hose upwards reaches the hydrocone type atomising head 8 at inner bag top, pools together with the gas woven hose.
So far after total system assembles, can begin to carry out the test of animal dynamic contamination.The ready soup of packing in medicine pond 5, start-up control system 3, the concentration of contamination of input experiment, contamination time, data such as the proportion of soup.Operational system then, controller is started working, and control fixed displacement pump 7 and air valve 13 feed flows, air feed start exhaust system 16 simultaneously; So soup and air begin to enter into inner bag 9 by atomising head 8 with vaporific form by preset ratio continuously.In system's operational process, control system 3 constantly detects the proportionate relationship of air feed and liquid supply rate, and controls by Air-regulating valves 12 and fixed displacement pump 7 in real time; Relevant temperature humidity data are by the automatic Be Controlled system log (SYSLOG) of temperature humidity probe 15 devices in this process; Whether infrared generation receiving sensor 14 monitoring soup in real time uses up and makes alarm.The time that so continues until experiment finishes.
Claims (7)
1, a kind of full-automatic dynamic contamination device is characterized in that: it is made up of control system, toxicity contaminated system, air flow system, liquid-supplying system, exhaust outlet system;
Control system mainly comprises computer system, single-chip microcomputer and governor circuit, is connected by cable between each system of control system and other, wherein the built-in control program of single-chip microcomputer;
Toxicity contaminated system comprises toxicant exposure cabinet, and the toxicant exposure cabinet center section adopts clear glass, and toxicant exposure cabinet inside is provided with inner bag, and the inner bag top is provided with atomising head, and inner bag is equipped with humidity temperature pickup; Atomising head connects air supply pipe and woven hose;
Air flow system includes compressor, gas meter, air valve, air supply pipe; Air compressor, gas meter, air valve connects together by air supply pipe, and air supply pipe is connected with atomising head; Gas meter, air valve link to each other with control system by cable;
The soup system comprises medicine pond, fixed displacement pump, lacks medicine warning device, woven hose; Lacking the medicine warning device is installed in around the medicine pond; Woven hose one end connects the medicine pond, and the other end connects atomising head; Fixed displacement pump is installed on the woven hose; Fixed displacement pump links to each other with control system by cable;
The exhaust outlet system mainly comprises blower fan, airduct, water pipe; Airduct, water pipe is connected with the inner bag bottom.
2, according to claim 1 described full-automatic dynamic contamination device, it is characterized in that: described atomising head is the hydrocone type atomising head.
2, according to claim 1 described full-automatic dynamic contamination device, it is characterized in that: described scarce medicine warning device is infrared generation receiving sensor.
3, according to claim 1 described full-automatic dynamic contamination device, it is characterized in that: described scarce medicine warning device is installed in bottom, medicine pond.
4, according to claim 1 described full-automatic dynamic contamination device, it is characterized in that: described fixed displacement pump is the creeping motion type fixed displacement pump.
5, according to claim 1 described full-automatic dynamic contamination device, it is characterized in that: temperature, humidity sensor are housed in the inner bag, and humidity temperature pickup links to each other with control system by cable.
6, according to claim 1 described full-automatic dynamic contamination device, it is characterized in that: inner bag adopts circular clear glass inner bag.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200320117313 CN2650134Y (en) | 2003-10-24 | 2003-10-24 | Fully-automatic dynamic contamination device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200320117313 CN2650134Y (en) | 2003-10-24 | 2003-10-24 | Fully-automatic dynamic contamination device |
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| Publication Number | Publication Date |
|---|---|
| CN2650134Y true CN2650134Y (en) | 2004-10-20 |
Family
ID=34346671
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|---|---|---|---|
| CN 200320117313 Expired - Fee Related CN2650134Y (en) | 2003-10-24 | 2003-10-24 | Fully-automatic dynamic contamination device |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100450635C (en) * | 2006-01-24 | 2009-01-14 | 广东省职业病防治院 | Liquid atomising device and its uses as drug addict device |
| CN102380433A (en) * | 2011-07-26 | 2012-03-21 | 天津开发区合普工贸有限公司 | Anti-explosion solid-phase dust contamination equipment |
| CN102488568A (en) * | 2011-12-08 | 2012-06-13 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | Animal gas contamination device |
| CN101514979B (en) * | 2009-03-31 | 2012-06-27 | 西安近代化学研究所 | Gunpowder-mixed fuel gas bio-toxicological experiment compartment |
| CN102670328A (en) * | 2012-05-29 | 2012-09-19 | 天津开发区合普工贸有限公司 | Pathogenic bacteria inhalation toxicology experimental equipment for respiratory system |
| CN103926382A (en) * | 2014-04-29 | 2014-07-16 | 国家电网公司 | Device for testing toxicity of sulfur hexafluoride gas |
| CN105092786A (en) * | 2015-07-23 | 2015-11-25 | 上海化工研究院 | Oppositely-impacting quantitative atomization drug delivery apparatus |
| CN105242008A (en) * | 2015-09-23 | 2016-01-13 | 同济大学 | Toxicant exposure testing apparatus used for regulating and controlling volatile organic compound gaseous-state pollution concentration |
| CN108721256A (en) * | 2018-09-04 | 2018-11-02 | 深圳市疾病预防控制中心（深圳市卫生检验中心、深圳市预防医学研究所） | A kind of construction method of mice lung cancer model |
-
2003
- 2003-10-24 CN CN 200320117313 patent/CN2650134Y/en not_active Expired - Fee Related
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100450635C (en) * | 2006-01-24 | 2009-01-14 | 广东省职业病防治院 | Liquid atomising device and its uses as drug addict device |
| CN101514979B (en) * | 2009-03-31 | 2012-06-27 | 西安近代化学研究所 | Gunpowder-mixed fuel gas bio-toxicological experiment compartment |
| CN102380433A (en) * | 2011-07-26 | 2012-03-21 | 天津开发区合普工贸有限公司 | Anti-explosion solid-phase dust contamination equipment |
| CN102380433B (en) * | 2011-07-26 | 2014-03-05 | 天津开发区合普工贸有限公司 | Anti-explosion solid-phase dust contamination equipment |
| CN102488568A (en) * | 2011-12-08 | 2012-06-13 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | Animal gas contamination device |
| CN102670328B (en) * | 2012-05-29 | 2015-03-25 | 天津开发区合普工贸有限公司 | Pathogenic bacteria inhalation toxicology experimental equipment for respiratory system |
| CN102670328A (en) * | 2012-05-29 | 2012-09-19 | 天津开发区合普工贸有限公司 | Pathogenic bacteria inhalation toxicology experimental equipment for respiratory system |
| CN103926382A (en) * | 2014-04-29 | 2014-07-16 | 国家电网公司 | Device for testing toxicity of sulfur hexafluoride gas |
| CN105092786A (en) * | 2015-07-23 | 2015-11-25 | 上海化工研究院 | Oppositely-impacting quantitative atomization drug delivery apparatus |
| CN105242008A (en) * | 2015-09-23 | 2016-01-13 | 同济大学 | Toxicant exposure testing apparatus used for regulating and controlling volatile organic compound gaseous-state pollution concentration |
| CN105242008B (en) * | 2015-09-23 | 2017-07-11 | 同济大学 | It is a kind of to be used to regulate and control the contamination experimental apparatus of volatile organic matter gaseous contamination concentration |
| CN108721256A (en) * | 2018-09-04 | 2018-11-02 | 深圳市疾病预防控制中心（深圳市卫生检验中心、深圳市预防医学研究所） | A kind of construction method of mice lung cancer model |
| CN108721256B (en) * | 2018-09-04 | 2019-11-26 | 深圳市疾病预防控制中心（深圳市卫生检验中心、深圳市预防医学研究所） | A kind of construction method of mice lung cancer model |
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Addressee: Wang Yonggang Document name: Notification of Termination of Patent Right |
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| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |