CN2595372Y - Disposable filter for removing white blood cell - Google Patents
Disposable filter for removing white blood cell Download PDFInfo
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- CN2595372Y CN2595372Y CN 03214544 CN03214544U CN2595372Y CN 2595372 Y CN2595372 Y CN 2595372Y CN 03214544 CN03214544 CN 03214544 CN 03214544 U CN03214544 U CN 03214544U CN 2595372 Y CN2595372 Y CN 2595372Y
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- blood
- filter
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Abstract
The utility model relates to a disposable filter for removing white cells, and belongs to a medical treatment instrument for filtering matters in bloods, which comprises a puncture needle, a white cell filter device and a blood storage bag, wherein the white cell filter device is composed of a blood inlet chamber, a filter layer and a blood outlet chamber where the blood respectively passes through. The blood inlet chamber and the blood outlet chamber are respectively positioned on both sides of the filter layer. The utility model is characterized in that the filter layer of the white cell filter device is a double structure which is composed of organic fibers with different hole diameters; the maximum hole diameter of the fiber layer on the blood inlet chamber side is 45 micrometers, and the maximum hole diameter of the fiber layer on the blood outlet chamber side is 25 micrometers. The simple structure and reasonable. The blood to be filtered uniformly passes through filter material with double layer, which can enhance the filter rate of the white cells and recovery rate of red cells. The filter rate of the white cells can achieve more than 99.99 %, the recovery rate of the red cells achieves more than 90 %, and the indexes are superior to national trade standard and blood station basic standards issued by the health ministry of China.
Description
Technical field
This utility model belongs to the medical treating instrument that leaches material in the blood, relates in particular to and leaches leukocytic defecator in a kind of blood.
Background technology
Blood transfusion is one of important means of clinical treatment, but because the leukocyte in the blood loses physiological function in the short time after leaving human body easily, has become a kind of pollutant, may cause patient's untoward reaction or infectious blood born diseases.Existing in the world many countries adopt various apparatuses to remove leukocyte in the blood (comprising whole blood and red blood cell suspension), and leucocyte content in the blood is reached in the safe content range, and using the leucocyte-removing filter is rule of thumb wherein.On April 1st, 2002, China National Drug Administration has issued the industry standard of disposable use leucocyte-removing filter, and this shows the use of removing the leukocyte device trend that is inevitable.The key parameter of estimating the leucocyte-removing filter is a leukocyte depletion rate, but because blood is valuable resource, must make full use of, so the erythrocyte response rate also is to estimate an important indicator of leucocyte-removing filter effectiveness.
Filtering material is to influence the key factor that leukocyte leaches rate, and in addition, time length and leukocytic rejection rate that blood stores behind the extraction human body also have certain relation.Clear and definite regulation in China's national sector standard: " RF type leucocyte-removing filter prepares the residue leukocyte count of 1 unit whole blood or red cell suspension should be less than 2.5 * 10
6Individual." present existing leucocyte-removing filter is about 95% to the leukocytic rate that leaches, can reach requirement basically, but still have certain gap with the industry standard ratio.October 18 nineteen ninety-five, disclosed Chinese patent application 94111296.9 provided a kind of glass fibre leucocyte filter, it is characterized in that: glass fibre leucocyte filter comprises housing, cap, adsorbed film and the filter membrane of filter, adsorbed film and filter membrane are made by containing the alkali ultra-fine fibre glass, settle the reinforcing membrane of the organic non-woven material of one deck between cap and filter membrane.It mainly is used in blood transfusion and has lost the leukocyte of physiological function to reduce or to avoid exothermic reaction, immunoreation, anaphylaxis and viral communication etc. because of transfusional untoward reaction in the filtering whole blood in filtering.But,, also have fat, lipid material and electrolyte as albumin, fibrin and immunoglobulin owing to contain the material that forms the polarity gel coat than leukocyte diameter greatly and easily in the blood plasma; Therefore leukocyte easy deformation in addition, physical form cause filter membrane to stop up greater than micropore easily, influences filter efficiency, and the while erythrocyte also has loss in various degree.
The utility model content
The purpose of this utility model provides a kind of disposable use leucocyte-removing filter, when reaching higher leukocyte depletion rate, improves the erythrocytic response rate to greatest extent.
The technical solution adopted in the utility model is: disposable use leucocyte-removing filter, comprise puncture needle, leucocyte filtration device and liquid storing bag, the intake chamber that leucocyte filtration device is passed through successively by blood, filter course and liquid outtake chamber form, intake chamber and liquid outtake chamber lay respectively at the both sides of filter course, it is characterized in that the filter course in the leucocyte filtration device is the double-decker that different apertures organic fiber is formed, the fibrolaminar maximum diameter of hole of intake chamber's side is 45 μ m, and the fibrolaminar maximum diameter of hole of liquid outtake chamber's side is 25 μ m.
The double-decker of filter course is attached to together by two fibrous layers to be formed.Filter course is the filtering material layer that superfine fibre is formed, find according to the study, glass fibre has to a certain degree destruction to blood constituent, influence the quality of filtering blood, generally adopt the PET polyester fiber to replace existing glass fibre, it is stronger to leukocytic absorbability, can adsorb a large amount of leukocyte, but the aperture of filtering material still must be controlled in the specific scope, makes adsorption efficiency reach rational requirement, the filter result conformance with standard.
Conduit between puncture needle and leucocyte filtration device is provided with the blood filtration net, can leach lipid macromole and most of storehouse blood clotting polymers before blood is by leucocyte filtration device in advance, the problem of gel layer appears in the filter course surface of minimizing in leucocyte filtration device.
For the aperture that guarantees adsorbing fiber layer and filter fiber layer blood or blood plasma by the time do not change, be provided with honeycomb texture in the outside of double medium filtration fiber.Intake chamber and liquid outtake chamber lay respectively at filter course lateral two ends up and down.Treat that blood passes through leucocyte filtration device, must pass through the honeycomb texture and the liquid outtake chamber of intake chamber, honeycomb texture, large aperture layer of polyester fiber, small-bore layer of polyester fiber, opposite side successively, flow out by liquid outlet at last by inlet.The effect of large aperture layer of polyester fiber is tentatively to adsorb leukocyte and virocyte, and the small-bore layer of polyester fiber plays strengthens filtering effect, and because erythrocyte greater than erythrocytic diameter, can be reclaimed to greatest extent in the aperture.
The beneficial effects of the utility model are, simple and reasonable, blood to be filtered is uniformly by the double medium filtration material, the leukocytic rejection rate and the erythrocytic response rate have been improved, leukocytic rejection rate can reach more than 99.99%, the erythrocyte response rate reaches more than 90%, and index all is better than the blood station basic standard of national sector standard and health ministry promulgation.
Description of drawings
Below in conjunction with drawings and Examples this utility model is further described.
Fig. 1 is the structural representation of this utility model embodiment;
Fig. 2 is that the A at I position among Fig. 1 is to cross section view.
The specific embodiment
Among embodiment such as the figure, disposable use leucocyte-removing filter comprises puncture needle 3, leucocyte filtration device 8 and liquid storing bag 9, leucocyte filtration device 8 forms 14 by intake chamber 16, filter course and the liquid outtake chamber that blood passes through successively, intake chamber 16 and liquid outtake chamber 14 lay respectively at the lateral two ends up and down of filter course, filter course is the double-decker that the organic fiber in different apertures is formed, the maximum diameter of hole of the fibrous layer 11 of intake chamber's 16 sides is 45 μ m, and the maximum diameter of hole of the fibrous layer 13 of liquid outtake chamber's 14 sides is 25 μ m.Large aperture fibrous layer and small-bore fibrous layer are attached to forms filter course together.The conduit that puncture needle 3 and leucocyte filtration device 8 are asked is provided with blood filtration net 5, parallel connection has saline puncture needle 2 and empty filter 1 on the conduit that puncture needle 3 and drainage screen are 5, after finishing, blood filtration can use the normal saline washing filter, reclaim erythrocyte to greatest extent, lay flow-stopping clip 4 on the conduit of connection puncture needle 1.Leucocyte filtration device and exhaustor 6 parallel connections that have flow-stopping clip 7, the rearmost end of conduit is a storage blood bag 9, leucocyte filtration device 8 is a flat type cylinder, and inlet 17 and liquid outlet 12 lay respectively at the both sides of its inner filtration layer, and the outside of double medium filtration fiber is provided with honeycomb texture 10 and 15.
Claims (5)
1, disposable use leucocyte-removing filter, comprise puncture needle, leucocyte filtration device and liquid storing bag, the intake chamber that leucocyte filtration device is passed through successively by blood, filter course and liquid outtake chamber form, intake chamber and liquid outtake chamber lay respectively at the both sides of filter course, it is characterized in that the filter course in the leucocyte filtration device (8) is (11) and (13) double-decker that different apertures organic fiber is formed, the maximum diameter of hole of the fibrous layer (11) of intake chamber (16) side is 45 μ m, and the maximum diameter of hole of the fibrous layer (13) of liquid outtake chamber (14) side is 25 μ m.
2, disposable use leucocyte-removing filter according to claim 1 is characterized in that intake chamber (16) and liquid outtake chamber (14) lay respectively at filter course lateral two ends up and down.
3, disposable use leucocyte-removing filter according to claim 1 is characterized in that the conduit between puncture needle (3) and leucocyte filtration device (8) is provided with blood filtration net (5).
4, disposable use leucocyte-removing filter according to claim 1 is characterized in that the both sides of double medium filtration layer are provided with honeycomb texture (10) and (15).
5, disposable use leucocyte-removing filter according to claim 1 is characterized in that the double medium filtration layer is attached to together by two fibrous layers to form.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03214544 CN2595372Y (en) | 2003-01-04 | 2003-01-04 | Disposable filter for removing white blood cell |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03214544 CN2595372Y (en) | 2003-01-04 | 2003-01-04 | Disposable filter for removing white blood cell |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2595372Y true CN2595372Y (en) | 2003-12-31 |
Family
ID=33754722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 03214544 Expired - Fee Related CN2595372Y (en) | 2003-01-04 | 2003-01-04 | Disposable filter for removing white blood cell |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2595372Y (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102205154A (en) * | 2010-03-30 | 2011-10-05 | 旭化成医疗株式会社 | Blood processing filter and blood filtering method adopting same |
-
2003
- 2003-01-04 CN CN 03214544 patent/CN2595372Y/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102205154A (en) * | 2010-03-30 | 2011-10-05 | 旭化成医疗株式会社 | Blood processing filter and blood filtering method adopting same |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |