CN201036634Y - White blood cell platelet removing filtering device and using white blood cell removing filtering component - Google Patents
White blood cell platelet removing filtering device and using white blood cell removing filtering component Download PDFInfo
- Publication number
- CN201036634Y CN201036634Y CNU2006200429643U CN200620042964U CN201036634Y CN 201036634 Y CN201036634 Y CN 201036634Y CN U2006200429643 U CNU2006200429643 U CN U2006200429643U CN 200620042964 U CN200620042964 U CN 200620042964U CN 201036634 Y CN201036634 Y CN 201036634Y
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- platelet
- leucocyte
- filtering
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Abstract
The utility model belongs to the technical field of disposable filtering device for removing leucocyte and platelet. The filtering device for removing leucocyte and platelet comprises an inlet duct(1), a flow-stopping clamp(2), a drip chamber(3) with blood transfusion filtering net, a filtering component(4) for removing the leucocyte, an exhaust duct(5), a flow regulator(6) and a platelet storage bag(7); the filtering component(4) for removing the leucocyte consists of a liquid inlet chamber(41), a filtering layer(42) with single component, a barrier layer(43) and a liquid outlet chamber(44) orderly. Being different from the filtering component for filtering the whole blood or red blood cell, the filtering component of the utility model only comprises a filtering layer with single component, so that the utility model can reduce the contract of the platelet and the materials to the maximum, improve recovery rate of platelet and prevent the activation of platelet. Moreover, the utility model not only has excellent performance, but also has low cost; if used extensively, the utility model can reduce greatly the invalid transfusion of NHFTR and platelet, and has great significance to improve security and validity of blood transfusion.
Description
Technical field
This utility model belongs to disposable leucocyte-removing platelet defecator technical field.
Background technology
Infusion contains leukocytic platelet can cause many untoward reaction.Invalid etc. as nonhemolytic febrific reaction (FNHTR), platelet infusion.Simultaneously, leukocyte is still had a liking for the carrier of leukocyte virus, as cytomegalovirus (MCV), human t lymphotropic virus (HTLV-I/II) and HIV (human immunodeficiency virus) (HIV) etc., blood transfusion may cause the activation of these viral menses propagation and latent virus.Adopting the leukocyte in the special-purpose filter filtering of the leucocyte-removing platelet, is simple and effective, the most the most frequently used so far method.Gong Ying leucocyte-removing platelet filter in the market, make with composites such as multiple new material such as ultra-fine fibre glass film, polyester and rustless steels, though can remove the leukocyte more than 99.99%, but because of hematoblastic special construction and biological property, be easy in filter process, be activated or be adsorbed, finally influence the hematoblastic response rate and clinical infusion effect.
Summary of the invention
The purpose of this utility model is the deficiency that overcomes existing leucocyte-removing platelet filter, provides a kind of and can improve recovery rate of blood platelet, can prevent the leucocyte-removing filter element of platelet activation again.
This utility model also has a purpose to provide to comprise the disposable leucocyte-removing platelet defecator of above-mentioned leucocyte-removing filter element.
For reaching above-mentioned purpose, the technical scheme that this utility model is taked is:
Disposable leucocyte-removing platelet defecator, this device comprises: inlet ducts, the dropping funnel that contains the drainage screen of transfusing blood, leucocyte-removing filter element, flow-stopping clip, flow regulator and platelet reservoir bag, wherein the leucocyte-removing filter element is made up of filter course, barrier layer and the liquid outtake chamber of intake chamber, single component successively.
Described filter course is made up of 2-16 layer non-woven fabrics, and the maximum diameter of hole of each single-layer nonwoven is less than 20 μ m, thickness 0.5-1.5mm; Non-woven fabrics is done the surface by the method for irradiation grafting, chemical graft, plasma or face coat and is handled, and improves the biocompatibility of platelet filtering material.Used hydrophilic monomer is cellulose family, saccharide, heparin, acrylic acid and derivant thereof or their mixture etc.The hydrophilic group of introducing has carboxyl, amino, hydroxyl etc.The surface tension of handling back platelet filter material is 50-200 dyne/cm
2This high efficiency filter material can be implemented in when reaching higher leukocyte depletion rate, reduces hematoblastic sticking and activation degree to greatest extent, improves the hematoblastic response rate, keeps hematoblastic vigor and function.
Described barrier layer is made up of surface treated non-woven fabrics or other porous material, and its maximum diameter of hole is not more than 15 μ m, and voidage is greater than 80%, and thickness is not more than 0.5mm.The barrier layer that surface treated non-woven fabrics or other porous material are formed, it has excellent biological compatibility to platelet.Both can hold back the lymphocyte that is difficult to filtering, improve leukocyte removal efficiency; The scalable rate of filtration again.
For preventing air trapping and raising recovery rate of blood platelet in the blood platelet storage bag, in leucocyte-removing platelet defecator, also can increase exhaust manifolds, can or filter when finishing in filter process and drain air in the bag by exhaust manifolds.
This utility model can be connected use with the blood bag that contains Platelet Concentrate, also leucocyte-removing filter device and Platelets Pheresis/Apheresis platelets pipeline can be used in combination.
The beneficial effects of the utility model: different with the filter element of filtering whole blood or red cell suspension, disposable leucocyte-removing platelet filter element of the present utility model only comprises the filter course of single component, can reduce contacting of platelet and material to greatest extent, improve recovery rate of blood platelet, prevent platelet activation.Hold back main leukocyte composition one lymphocyte that causes transfusion reaction by the barrier layer.More effectively prevent the blood transfusion side reaction that leukocyte causes.Leukocyte removal efficiency and recovery rate of blood platelet are approaching or surpass inlet filter, filter the back leukocyte removal efficiency greater than 99.99%; Recovery rate of blood platelet is greater than 80%.This utility model is function admirable not only, and with low cost, will significantly reduce NHFTR and the invalid generation of platelet infusion as being extensive use of, and is significant with the blood transfusion effectiveness to improving transfusion safety.
Description of drawings
Fig. 1 is the structural representation of leucocyte-removing filter element
Fig. 2 is disposable leucocyte-removing platelet filter apparatus configuration sketch map
The specific embodiment
Below in conjunction with accompanying drawing the leucocyte-removing filter element of disposable leucocyte-removing platelet defecator of the present utility model and use thereof is done a detailed description.
As shown in Figure 1, leucocyte-removing filter element described in the utility model is made up of filter course 42, barrier layer 43 and the liquid outtake chamber 44 of intake chamber 41, single component successively.
Wherein filter course is made up of 2-16 layer non-woven fabrics, and the maximum diameter of hole of each single-layer nonwoven is less than 20 μ m, thickness 0.5-1.5mm; The barrier layer is made up of non-woven fabrics or other porous material, and its maximum diameter of hole is not more than 15 μ m, and voidage is greater than 80%, and thickness is not more than 0.5mm.
As Fig. 2 and shown in Figure 1, disposable leucocyte-removing platelet defecator described in the utility model comprises inlet ducts 1, flow-stopping clip 2, contains dropping funnel 3, leukoreduction filter parts 4, exhaust manifolds 5, flow regulator 6 and the platelet reservoir bag 7 of the drainage screen of transfusing blood, and wherein the leukoreduction filter parts are made up of filter course 42, barrier layer 43 and the liquid outtake chamber 44 of intake chamber 41, single component successively.
Disposable leucocyte-removing platelet filter is connected with the platelet product bag is aseptic by inlet ducts, contain leukocytic platelet product with conduct oneself with dignity mobile mode successively by inlet ducts, contain the dropping funnel and the leukoreduction filter parts of the drainage screen of transfusing blood, enter the platelet reservoir bag.Drain air in the platelet reservoir bag by exhaust manifolds 5, obtain the Platelet Concentrate goods of leucocyte-removing.
Leucocyte-removing filter element of the present utility model, exhaust manifolds, flow-stopping clip and flow regulator are also capable of being combined between the transfer bag and platelet reservoir bag of Platelets Pheresis/Apheresis platelets pipeline.The platelet of gathering can be in batches or is disposablely filtered by leucocyte filtration device, filters to finish the back and drain air in the platelet reservoir bag by exhaust manifolds 5.Obtain the Platelets Pheresis/Apheresis platelets goods of leucocyte-removing.
Claims (4)
1. leucocyte-removing filter element, it is characterized in that: these parts are made up of filter course (42), barrier layer (43) and the liquid outtake chamber (44) of intake chamber (41), single component successively.
2. leucocyte-removing filter element as claimed in claim 1 is characterized in that: filter course is made up of the surface treated non-woven fabrics of 2-16 layer, and the maximum diameter of hole of non-woven fabrics is less than 20 μ m, thickness 0.5-1.5mm.
3. leucocyte-removing filter element as claimed in claim 1 is characterized in that: the barrier layer is made up of non-woven fabrics or other porous material, and its maximum diameter of hole is not more than 15 μ m, and voidage is greater than 80%, and thickness is not more than 0.5mm.
4. leucocyte-removing platelet defecator, this device comprises inlet ducts (1), flow-stopping clip (2), contains the dropping funnel (3) of the drainage screen of transfusing blood, leucocyte-removing filter element (4), exhaust manifolds (5), flow regulator (6) and platelet reservoir bag (7), it is characterized in that: this leucocyte-removing filter element is made up of filter course (42), barrier layer (43) and the liquid outtake chamber (44) of intake chamber (41), single component successively.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2006200429643U CN201036634Y (en) | 2006-06-20 | 2006-06-20 | White blood cell platelet removing filtering device and using white blood cell removing filtering component |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2006200429643U CN201036634Y (en) | 2006-06-20 | 2006-06-20 | White blood cell platelet removing filtering device and using white blood cell removing filtering component |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201036634Y true CN201036634Y (en) | 2008-03-19 |
Family
ID=39209141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2006200429643U Expired - Lifetime CN201036634Y (en) | 2006-06-20 | 2006-06-20 | White blood cell platelet removing filtering device and using white blood cell removing filtering component |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201036634Y (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102357319A (en) * | 2011-08-11 | 2012-02-22 | 陶志勇 | Filtration apparatus for removing leucocytes from plasmodium-infected blood |
| CN111032118A (en) * | 2017-09-28 | 2020-04-17 | 泰尔茂株式会社 | Blood transfusion set, blood transfusion system, blood transfusion set for emergency blood transfusion, and method for using blood transfusion set |
-
2006
- 2006-06-20 CN CNU2006200429643U patent/CN201036634Y/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102357319A (en) * | 2011-08-11 | 2012-02-22 | 陶志勇 | Filtration apparatus for removing leucocytes from plasmodium-infected blood |
| CN111032118A (en) * | 2017-09-28 | 2020-04-17 | 泰尔茂株式会社 | Blood transfusion set, blood transfusion system, blood transfusion set for emergency blood transfusion, and method for using blood transfusion set |
| US11883570B2 (en) | 2017-09-28 | 2024-01-30 | Terumo Kabushiki Kaisha | Blood transfusion kit and system and method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20080319 |
|
| EXPY | Termination of patent right or utility model |