CN2543056Y - Immunohistochemistry dyeing automatic controller - Google Patents
Immunohistochemistry dyeing automatic controller Download PDFInfo
- Publication number
- CN2543056Y CN2543056Y CN 02217593 CN02217593U CN2543056Y CN 2543056 Y CN2543056 Y CN 2543056Y CN 02217593 CN02217593 CN 02217593 CN 02217593 U CN02217593 U CN 02217593U CN 2543056 Y CN2543056 Y CN 2543056Y
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Abstract
The utility model discloses an automatic controlling device for immunohistochemical staining, and comprises a slice control mechanism installed on a chassis, a reagent control mechanism, a washing mechanism, a screw down mechanism, and a computer control and display mechanism, wherein a slice fixation plate is installed on a vertical shaft through a bearing; a reagent fixation plate is installed on the vertical shaft through a bearing and is positioned above the slice fixation plate; slices are installed above the outer side along the circumference of the slice fixation plate, whereas a bearing is installed on the internal side of the circumference, and a plurality of drain holes are arranged at the center along the direction of the circumference; a waterspout is installed under the drain holes; the washing mechanism is installed on the chassis; a punch is installed on a bracket through a sliding bush and positioned above the reagent fixation plate. The utility model has the following advantages: (1) the shape and the volume of the device are small, while slices and reagent that can be placed in the device are numerous; (2) an operation of a batch quality can be realized to dozens of slices at the same time, and the working intensity can be reduced, the working efficiency improved; (3) operation procedures like adding, waiting for the reaction and washing of the reagent are controlled by a computer, and thus the controlling precision is high and the testing results are accurate.
Description
Technical field
The utility model body relates to a kind of immunohistochemical staining automaton.
Background technology
Immunohistochemical staining is a test of clinical medicine pathological diagnosis.Its operation steps is that the biological tissue that is fixed in the section is added certain reagent, reacts, and cleans after the reaction time in accordance with regulations is intact; And then add another kind of reagent, react, wait for, clean; So repeatedly, until the reagent total overall reaction of regulation is intact.According to the colouring method difference that is adopted, tens steps are generally wanted in this test.Because hospital need handle a large amount of sections every day, each section is tens operation stepss again, and also want strictness to control the stand-by period of reaction and the clean level of cleaning in the operation, not only labour intensity is big to adopt artificial test method, and reaction time and the also very difficult control of the degree that cleans up, inefficiency.
Summary of the invention
The purpose of this utility model provides a kind of automaton of immunohistochemical staining.
It has section control gear, reagent control gear, wiper mechanism, screw-down and computer control and the indication mechanism that is installed on the base; Said section control gear has section shaft collar, section control motor, gear, bearing; The reagent control gear has immobilization of reagents dish, reagent control motor, gear, bearing; Wiper mechanism has the motor of cleaning, cleans support, shaft coupling, leading screw, slide bar, slide block, cleaning head, washer, photoelectric sensor; Screw-down has the motor of depressing, depresses support, cam, drift, spring, sliding sleeve; On column, on column, the immobilization of reagents dish is positioned at the top of section shaft collar to the immobilization of reagents dish to the section shaft collar by Bearing Installation by Bearing Installation; The section shaft collar is installed section along the periphery top, and the inboard is a bearing, and the centre along the circumferential direction is several osculums, and rhone is installed in the osculum below; Wiper mechanism is installed on the base; Drift is rack-mount by sliding sleeve, is positioned at the top of immobilization of reagents dish.
The utlity model has following advantage:
(1) section shaft collar and immobilization of reagents rim circumferencial direction are installed section and reagent, thereby the device overall volume is little, and it is many to lay section and reagent;
(2) can realize the mass operation to tens of sections simultaneously, alleviate working strength, increase work efficiency;
(3) adopt computer control reagent to add to, react operation stepss such as wait and cleaning, the control accuracy height, test findings is accurate.
Description of drawings
Fig. 1 is the utility model general structure synoptic diagram;
Fig. 2 is a wiper mechanism synoptic diagram of the present utility model.
Among Fig. 1: 1 base, 2 columns, 3 bearings, 4 rhones, 5 outer Knucle-gears, 6 section control motors, 7 sections, 8 section shaft collars, 9 wiper mechanisms, 10 supports, 11 are depressed motor, 12 stamped bracket, 13, cam, 14, staking punch, 15, spring, 16 sliding sleeves, 17 reagent throwers, 18 immobilization of reagents dishes, 19, outer Knucle-gear, 20 bearings, 21 reagent control motor.
Among Fig. 2: 22 clean motor, 23 cleaning machine supports, 24 shaft couplings, 25 leading screws, 26 slide bars, 27 washers, 28 slide blocks, 29 cleaning heads, 30 photoelectric sensors, 31 cleaning fluid pipes
Embodiment
The immunohistochemical staining automaton has section control gear, reagent control gear, wiper mechanism, screw-down and computer control and the indication mechanism that is installed on the base; Said section control gear has section shaft collar 8, section control motor 6, gear 5, bearing 3; The reagent control gear has immobilization of reagents dish 18, reagent control motor 21, gear 19, bearing 20; Wiper mechanism has the motor 22 of cleaning, cleans support 23, shaft coupling 24, leading screw 25, slide bar 26, slide block 28, cleaning head 29, washer 27, photoelectric sensor 30; Screw-down has the motor of depressing 11, depresses support 12, cam 13, drift 14, spring 15, sliding sleeve 16; Section shaft collar [8] is installed on the column 2 by bearing 3, and the immobilization of reagents dish is installed on the column 2 by bearing 20, and the immobilization of reagents dish is positioned at the top of section shaft collar; The section shaft collar is installed section 7 along the periphery top, and the inboard is a bearing 3, and the centre along the circumferential direction is several osculums, and rhone 4 is installed in the osculum below; Wiper mechanism 9 is installed on the base 1; Drift 14 is installed on the support 10 by sliding sleeve 15, is positioned at the top of immobilization of reagents dish.
Said section control motor 6 drives outer Knucle-gear 5, and the internal-round gear wheel engagement with section shaft collar 8 belows drives the section shaft collar and rotates.
Section shaft collar 8 is installed section 7 along the circumference top, and the inboard is fixed on the column 2 by bearing 3; Between section 7 and bearing 3, the section shaft collar has several leaking holes; Rhone 4 is installed below the osculum of section shaft collar.
During work, reagent control motor drives the immobilization of reagents dish by gearing mesh, and the reagent thrower of needs is forwarded under the staking punch; Section control motor drives the section shaft collar by gearing mesh, and the section that needs is added to reagent forwards reagent thrower below successively to; Whenever there is a section to turn over, depresses motor and rotate once, drive cam rotation, staking punch is depressed, rely on again on the spring bullet, when depressing, the reagent thrower is once depressed, the reagent in the reagent thrower is ejected in the section; React wait according to computer-controlled program then.After reaction was arrived the stand-by period, section control motor drove the section shaft collar by gearing mesh, and the section that needs are cleaned forwards the below of cleaning head successively to; Cleaning head is under the promotion of cleaning motor, and is reciprocating at slice surface, cleaning fluid in the water pipe on the cleaning head dashed be spread across slice surface, and flow in the round rhone along section dish leaking hole, discharges.
The course of work of device is as follows: reagent control motor 21 drives immobilization of reagents dishes 18 by gear 19 engagements, forwards the reagent thrower 17 of needs to staking punch 14 times; Section control motor 6 drives section shaft collar 8 by gear 5 engagements, and the section 7 that needs is added to reagent forwards reagent thrower 17 belows successively to; Whenever there is a section to turn over, depresses motor 11 and rotate once, drive cam 13 and rotate, staking punch 14 is depressed, relied on again on spring 15 bullets, when depressing, reagent thrower 17 is once depressed, the reagent in the reagent thrower 17 is ejected in the section 7; React wait according to computer-controlled program then.After the reaction stand-by period arrived, section was controlled motor 6 and is driven section shaft collar 8 by gear 5 engagements, the section 7 of needs cleaning is forwarded successively to the below of cleaning head 29; Cleaning head 29 is under the promotion of cleaning motor 22, and is reciprocating on section 7 surfaces, cleaning fluid in the water pipe 31 on the cleaning head 29 dashed be spread across section 7 surfaces, and coil 8 leaking holes along section and flow in the round rhone 4, discharges.
Claims (5)
1. an immunohistochemical staining automaton is characterized in that it has section control gear, reagent control gear, wiper mechanism, screw-down and computer control and the indication mechanism that is installed on the base; Said section control gear has section shaft collar [8], section control motor [6], gear [5], bearing [3]; The reagent control gear has immobilization of reagents dish [18], reagent control motor [21], gear [19], bearing [20]; Wiper mechanism has cleaning motor [22], cleans support [23], shaft coupling [24], leading screw [25], slide bar [26], slide block [28], cleaning head [29], washer [27], photoelectric sensor [30]; Screw-down has the motor of depressing [11], depresses support [12], cam [13], drift [14], spring [15], sliding sleeve [16]; Section shaft collar [8] is installed on the column [2] by bearing [3], and the immobilization of reagents dish is installed on the column [2] by bearing [20], and the immobilization of reagents dish is positioned at the top of section shaft collar; The section shaft collar is installed section [7] along the periphery top, and the inboard is bearing [3], and the centre along the circumferential direction is several osculums, and rhone [4] is installed in the osculum below; Wiper mechanism [9] is installed on the base [1]; Drift [14] is installed on the support [10] by sliding sleeve [15], is positioned at the top of immobilization of reagents dish.
2. a kind of immunohistochemical staining automaton according to claim 1 is characterized in that: said section control motor [6] drives outer Knucle-gear [5], and the internal-round gear wheel engagement with section shaft collar [8] below drives the section shaft collar and rotates.
3. a kind of immunohistochemical staining automaton according to claim 1 is characterized in that: said section shaft collar [8] is installed section [7] along the circumference top, and the inboard is fixed on the column [2] by bearing [3]; Between section [7] and bearing [3], the section shaft collar has several leaking holes; Below the osculum of section shaft collar, rhone [4] is installed.
4. a kind of immunohistochemical staining automaton according to claim 1 is characterized in that: said reagent control motor [21] drives outer Knucle-gear [19], and the internal-round gear wheel engagement with immobilization of reagents dish [18] below drives the immobilization of reagents dish and rotates.
5. a kind of immunohistochemical staining automaton according to claim 1, it is characterized in that: said cleaning motor [22] connects with leading screw [25] by shaft coupling [24], leading screw [25] is threaded with slide block [28], slide block [28] is slidingly connected with slide bar [26], cleaning head [29] is fixed on slide block [28] below, slide block [28] below is equipped with plate washer [27], cleans an end of support [23] photoelectric sensor [30] is installed, and cleaning head [29] is gone up fixedly cleaning fluid pipe [31].
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02217593 CN2543056Y (en) | 2002-05-20 | 2002-05-20 | Immunohistochemistry dyeing automatic controller |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02217593 CN2543056Y (en) | 2002-05-20 | 2002-05-20 | Immunohistochemistry dyeing automatic controller |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2543056Y true CN2543056Y (en) | 2003-04-02 |
Family
ID=33696379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02217593 Expired - Fee Related CN2543056Y (en) | 2002-05-20 | 2002-05-20 | Immunohistochemistry dyeing automatic controller |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2543056Y (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101799478A (en) * | 2010-03-12 | 2010-08-11 | 郑州博赛生物技术股份有限公司 | Reagent tray device for automatic immunity analyzer |
| CN102183400A (en) * | 2011-01-31 | 2011-09-14 | 浙江世纪康大医疗科技有限公司 | Dyeing instrument antibody accommodating device |
| CN102213655A (en) * | 2011-03-15 | 2011-10-12 | 江苏大学 | Full-automatic microbial staining film production equipment and staining method |
| CN102519775A (en) * | 2011-11-15 | 2012-06-27 | 深圳市科软科技有限公司 | Automatic slide stainer |
| CN103033609A (en) * | 2011-09-30 | 2013-04-10 | 奥索临床诊断有限公司 | Disposable foil punch for immunohematology test elements |
| CN103149070A (en) * | 2013-03-11 | 2013-06-12 | 黄石市第一医院 | Automatic slide stainer |
| CN107907396A (en) * | 2017-11-07 | 2018-04-13 | 山西大学 | A kind of biological tissue's active immunity histochemical staining system |
| CN108414330A (en) * | 2018-03-14 | 2018-08-17 | 福州迈新生物技术开发有限公司 | A kind of improved structure of sample staining modules for automatic slide stainer |
-
2002
- 2002-05-20 CN CN 02217593 patent/CN2543056Y/en not_active Expired - Fee Related
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101799478A (en) * | 2010-03-12 | 2010-08-11 | 郑州博赛生物技术股份有限公司 | Reagent tray device for automatic immunity analyzer |
| CN101799478B (en) * | 2010-03-12 | 2012-08-29 | 郑州博赛生物技术股份有限公司 | Reagent tray device for automatic immunity analyzer |
| CN102183400A (en) * | 2011-01-31 | 2011-09-14 | 浙江世纪康大医疗科技有限公司 | Dyeing instrument antibody accommodating device |
| CN102183400B (en) * | 2011-01-31 | 2012-11-14 | 浙江世纪康大医疗科技有限公司 | Dyeing instrument antibody accommodating device |
| CN102213655A (en) * | 2011-03-15 | 2011-10-12 | 江苏大学 | Full-automatic microbial staining film production equipment and staining method |
| CN102213655B (en) * | 2011-03-15 | 2013-06-12 | 江苏大学 | Full-automatic microbial staining film production equipment and staining method |
| CN103033609A (en) * | 2011-09-30 | 2013-04-10 | 奥索临床诊断有限公司 | Disposable foil punch for immunohematology test elements |
| CN102519775A (en) * | 2011-11-15 | 2012-06-27 | 深圳市科软科技有限公司 | Automatic slide stainer |
| CN103149070A (en) * | 2013-03-11 | 2013-06-12 | 黄石市第一医院 | Automatic slide stainer |
| CN107907396A (en) * | 2017-11-07 | 2018-04-13 | 山西大学 | A kind of biological tissue's active immunity histochemical staining system |
| CN108414330A (en) * | 2018-03-14 | 2018-08-17 | 福州迈新生物技术开发有限公司 | A kind of improved structure of sample staining modules for automatic slide stainer |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |