CN2485656Y - Plasma separating and analyzing reagnet box - Google Patents
Plasma separating and analyzing reagnet box Download PDFInfo
- Publication number
- CN2485656Y CN2485656Y CN 01227580 CN01227580U CN2485656Y CN 2485656 Y CN2485656 Y CN 2485656Y CN 01227580 CN01227580 CN 01227580 CN 01227580 U CN01227580 U CN 01227580U CN 2485656 Y CN2485656 Y CN 2485656Y
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- film
- pad
- hemofiltration
- membrane
- blood
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Abstract
The utility model discloses a plasma separating and testing reagent box, which comprises a supporting base piece made of waterproof rigid material. A blood filtering membrane curtain is stuck at the supporting base piece. A testing membrane is stuck at the supporting base piece, and one end of the testing membrane is connected with the blood filtering membrane curtain. A waterproof separating membrane is attached at the end of the blood filtering membrane curtain of the connecting place of the testing membrane and the blood filtering membrane curtain, and the other end is stick at the top of the blood filtering membrane curtain. In order to make the blood corpuscle filter more thorough and penetrate quicker, a blood filter membrane and a blood dispersing membrane liner can be additionally arranged in the utility model. Due to simple structure and convenient use, the utility model is a good tool for quick test with micro-whole blood.
Description
The utility model relates to a kind of detection kit, and particularly a kind of micro whole blood that uses directly detects the kit of some material at the blood plasma intensive amount.
The normal concentration by measuring some material in the blood or whether have the diagnosis of carrying out disease clinically.In the blood testing commonly used (as paper chromatography), all need observe change in color then to determine the blood levels of determinand with immobilon-p or film pad as the support of reagent.Owing to contain a large amount of red blood cells in the whole blood, blood is taken on a red color or peony, so, if in test, adopt whole blood, be difficult to or can't directly judge the result of detection.For this reason, during clinical examination, must at first from whole blood, isolate fresh plasma, measure then.Plasma separation method commonly used has centrifuge method, natural sedimentation and membrane filter method.The above two or need Special Equipment or needs are placed the long time, make troubles to detection.Membrane filter method is present most convenient and micro-fast plasma separation method, mainly be divided into rectilinear and two kinds of side direction types (or horizontal) (patent US5186843, US5240862, EP586789, WO9610177, WO960394).Rectilinear high to the filtering membrane requirement, therefore, the cost of film is higher.Side direction type to film require relatively low, but present all diagnostic kits on the domestic and international market, after adding blood sample, haemocyte and blood plasma while swimming forward, the mobility speed by blood plasma is greater than the principle separated plasma of the mobility speed of haemocyte.With regard to diagnostic kit at present commonly used, side direction type hemofiltration film pad adds behind the blood sample 4-6 minute just has haemocyte to enter the detection film, influences result's observation.And general clinical detection whole blood often needs 15-20 minute reaction time after adding blood sample, and therefore the filtering membrane of this side direction type also far can not satisfy the needs of clinical detection.
The purpose of this utility model provide a kind of can be fast with haemocyte and separating plasma, can carry out the kit that separating plasma detects with micro whole blood.
For achieving the above object, the utility model is taked following design proposal: the separating plasma detection kit, and it comprises:
Support egative film, make by waterproof hard material;
Hemofiltration film pad sticks on and supports on the egative film;
Detect film, stick on and support on the egative film, an end and hemofiltration film pad join;
Barrier film is fluid-tight film, and an end is pasted on the hemofiltration film pad end that detects film and hemofiltration film pad joint, and a relative end is pasted on the top of hemofiltration film pad in addition; Barrier film be shorter in length than described hemofiltration film pad.
In order to make haemocyte filter more thoroughly, be provided with the additional hemofiltration film pad of one deck at least on the described hemofiltration film pad, the sidewall of the nearly described detection film end of this additional hemofiltration film pad is provided with waterproof membrane, and the bottom of waterproof membrane and described barrier film join.
In actual the use, the relation between balance cost and the effect, additional hemofiltration film pad is good with two layers.
In order to accelerate the infiltration rate of blood, be placed with one deck blood dispersion membrane pad at least on the described hemofiltration film pad, the sidewall of the nearly described detection film end of this blood dispersion membrane pad is provided with dispersion membrane pad waterproof membrane, and the bottom and the described barrier film of dispersion membrane pad waterproof membrane join.When being provided with additional hemofiltration film pad on the hemofiltration film pad, blood dispersion membrane pad is placed on the additional hemofiltration film pad, and described waterproof membrane extends to the top of blood dispersion membrane pad.
It is thick that blood plasma is done, and increases surface tension simultaneously to make blood plasma walk faster, is pasted with transparent, fluid-tight diaphragm seal at the top of described detection film.
In order to make blood plasma increase attractive force fast by detecting film to blood plasma, on the detection film of end that joins away from described detection film and hemofiltration film pad, be connected an absorption layer, this absorption layer sticks on and supports on the egative film.
In order to form stronger surface tension, be pasted with fluid-tight capping at described absorption layer top.
The present invention is owing to taked above-mentioned design, and after whole blood was added on the dispersion membrane pad, blood scattered rapidly and infiltrates in the film pad, and infiltration downwards filters out a part of haemocyte by additional hemofiltration film then, continues downwards by hemofiltration film pad.Owing to be provided with waterproof membrane between additional hemofiltration film pad and the described hemofiltration film pad, so the whole blood side direction is held back whole haemocytes by hemofiltration film pad, blood plasma is then along hemofiltration film pad, the detection film moves forward, and measures the content of required detection detecting membrane portions, enters the adsorption film pad at last.Barrier film can guarantee that liquid flows by additional hemofiltration film pad and hemofiltration film pad, can not flow directly into the detection film downwards.By which floor filtration, haemocyte is trapped in additional hemofiltration film pad and the hemofiltration film pad substantially fully, its speed that moves forward of haemocyte that does not have to be detained also lags far behind the translational speed of blood plasma, can guarantee that haemocyte does not enter in time of at least 20 minutes to detect in the film.
The utility model is simple in structure, and cost is low, and is easy to use, and it is accurate to detect effect, is a kind of good tool of using micro whole blood can carry out fast detecting.
Below in conjunction with accompanying drawing embodiment of the present utility model is described further.
Fig. 1 is a structural representation of the present utility model
Fig. 2 is the vertical view of Fig. 1
As shown in Figure 1 and Figure 2, the utility model comprises the support egative film 1 that rigid plastic is made, the hemofiltration film pad 2 of the haemocyte separating plasma pad material that commercially available side direction type diagnostic kit is used, the detection film 3 that commercially available diagnostic kit is used, the absorption layer 4 that commercially available diagnostic kit is used, two layers of additional hemofiltration film pad 6 with hemofiltration film pad 2 identical materials, the blood dispersion membrane pad 7 (making) that the commercially available diagnostic kit of one deck is used as materials such as available Polyester or Glass Fiber, fluid-tight barrier film 8, transparent diaphragm seal 10, fluid-tight capping 5, fluid-tight waterproof membrane 11.
As shown in Figure 1, hemofiltration film pad 2 detects film 3, absorption layer 4 sticks on successively and supports on the egative film 1, the two ends of detecting film 3 are connected with absorption layer 4 with hemofiltration film pad 2 respectively, and have mutually certain overlapping, to guarantee that liquid can move to another film from a kind of film.
Be provided with two layers of additional hemofiltration film pad 6 on the hemofiltration film pad 2, the additional hemofiltration film pad 6 nearly sidewalls that detect film 3 ends are provided with waterproof membrane 11, and the bottom of waterproof membrane 11 and barrier film 8 sealings are joined and become one.
Be placed with one deck blood dispersion membrane pad 7 on the additional hemofiltration film pad 6, waterproof membrane 11 extends to the top of blood dispersion membrane pad.
In the above-described embodiments, the number of plies of additional hemofiltration film pad 6 and blood dispersion membrane pad 7, barrier film 8 all can be adjusted according to actual conditions with the length of capping 5.The material of hemofiltration film pad 2, additional hemofiltration film pad 6, blood dispersion membrane pad 7 and absorption layer 4 also not only is confined to available reagent box material therefor.
Claims (9)
1, separating plasma detection kit is characterized in that it comprises:
Support egative film, make by waterproof hard material;
Hemofiltration film pad sticks on and supports on the egative film;
Detect film, stick on and support on the egative film, an end and hemofiltration film pad join;
Barrier film is fluid-tight film, and an end is pasted on the hemofiltration film pad end that detects film and hemofiltration film pad joint, and a relative end is pasted on the top of hemofiltration film pad in addition; Barrier film be shorter in length than described hemofiltration film pad.
2, separating plasma detection kit according to claim 1, it is characterized in that: be provided with the additional hemofiltration film pad of one deck at least on the described hemofiltration film pad, the sidewall that should add the nearly described detection film end of hemofiltration film pad is provided with waterproof membrane, and the bottom of waterproof membrane and described barrier film join.
3, separating plasma detection kit according to claim 1 is characterized in that: described additional hemofiltration film pad is two layers.
4, separating plasma detection kit according to claim 1, it is characterized in that: be placed with one deck blood dispersion membrane pad at least on the described hemofiltration film pad, the sidewall of the nearly described detection film end of this blood dispersion membrane pad is provided with dispersion membrane pad waterproof membrane, and the bottom and the described barrier film of dispersion membrane pad waterproof membrane join.。
5, separating plasma detection kit according to claim 2 is characterized in that: be placed with one deck blood dispersion membrane pad at least on the described additional hemofiltration film pad, described waterproof membrane extends to the top of blood dispersion membrane pad.
6, according to claim 1 or 2 or 3 or 4 described separating plasma detection kit, it is characterized in that: be pasted with transparent, fluid-tight diaphragm seal at the top of described detection film.
7, according to claim 1 or 2 or 3 or 4 described separating plasma detection kit, it is characterized in that: be connected an absorption layer on the detection film of end that joins away from described detection film and hemofiltration film pad, this absorption layer sticks on and supports on the egative film.
8, separating plasma detection kit according to claim 7 is characterized in that: be pasted with fluid-tight capping at described absorption layer top.
9, according to claim 4 or 5 described separating plasma detection kit, it is characterized in that: described dispersion membrane pad is one deck.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01227580 CN2485656Y (en) | 2001-06-20 | 2001-06-20 | Plasma separating and analyzing reagnet box |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01227580 CN2485656Y (en) | 2001-06-20 | 2001-06-20 | Plasma separating and analyzing reagnet box |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2485656Y true CN2485656Y (en) | 2002-04-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 01227580 Expired - Fee Related CN2485656Y (en) | 2001-06-20 | 2001-06-20 | Plasma separating and analyzing reagnet box |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2485656Y (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1759316B (en) * | 2003-03-10 | 2010-10-06 | 爱科来株式会社 | Blood cell separation membrane and blood retention tool including the same |
| CN101819198B (en) * | 2003-03-10 | 2012-07-18 | 爱科来株式会社 | Blood cell separation membrane |
| CN101965225B (en) * | 2008-03-11 | 2014-04-30 | 皇家飞利浦电子股份有限公司 | Filtering apparatus for filtering a fluid |
| CN105092323A (en) * | 2014-04-28 | 2015-11-25 | 深圳迈瑞生物医疗电子股份有限公司 | Method for adjusting blood film characteristics of blood smear pushed by push piece machine |
-
2001
- 2001-06-20 CN CN 01227580 patent/CN2485656Y/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1759316B (en) * | 2003-03-10 | 2010-10-06 | 爱科来株式会社 | Blood cell separation membrane and blood retention tool including the same |
| CN101819198B (en) * | 2003-03-10 | 2012-07-18 | 爱科来株式会社 | Blood cell separation membrane |
| CN101965225B (en) * | 2008-03-11 | 2014-04-30 | 皇家飞利浦电子股份有限公司 | Filtering apparatus for filtering a fluid |
| CN105092323A (en) * | 2014-04-28 | 2015-11-25 | 深圳迈瑞生物医疗电子股份有限公司 | Method for adjusting blood film characteristics of blood smear pushed by push piece machine |
| CN105092323B (en) * | 2014-04-28 | 2018-03-13 | 深圳迈瑞生物医疗电子股份有限公司 | A kind of blood film characterization method for adjusting sheet pushing machine and releasing blood film |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |