CN2414415Y - Capillary tube electrophoresis high-frequency conductivity tester - Google Patents
Capillary tube electrophoresis high-frequency conductivity tester Download PDFInfo
- Publication number
- CN2414415Y CN2414415Y CN 99256001 CN99256001U CN2414415Y CN 2414415 Y CN2414415 Y CN 2414415Y CN 99256001 CN99256001 CN 99256001 CN 99256001 U CN99256001 U CN 99256001U CN 2414415 Y CN2414415 Y CN 2414415Y
- Authority
- CN
- China
- Prior art keywords
- detecting device
- high frequency
- utility
- model
- capillary electrophoresis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000001962 electrophoresis Methods 0.000 title description 2
- 239000002184 metal Substances 0.000 claims abstract description 9
- 238000005251 capillar electrophoresis Methods 0.000 claims description 11
- 230000010355 oscillation Effects 0.000 claims description 2
- 230000002093 peripheral effect Effects 0.000 claims description 2
- 239000011241 protective layer Substances 0.000 abstract description 2
- 230000007547 defect Effects 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 description 5
- 238000010521 absorption reaction Methods 0.000 description 3
- 238000001499 laser induced fluorescence spectroscopy Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000001514 detection method Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 1
- 230000005518 electrochemistry Effects 0.000 description 1
- 238000007772 electroless plating Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
Images
Landscapes
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Abstract
The utility model relates to an analyzer which is composed of a high-frequency oscillating circuit, a voltage follower, a current-voltage converter, a high-frequency conducting electrode, etc. When the utility model is applied, only a separating capillary passes through a tubular metal electrode, and thus, the utility model with overcomes the defect of direct contact of the traditional solution; besides, the user doesn't need to carefully scrape off a protective layer on the outer wall of the capillary with a knife like using a tester of the optical class. All the is the advantages of the utility model.
Description
The utility model relates to a kind of analytical instrument, or the parts of analytical instrument.
Capillary Electrophoresis is that developed recently is rapid, a kind of very widely method for separating and analyzing of application, is considered to one of most important analytical approach of the nineties.Detecting device is the important composition part of capillary electrophoresis apparatus, directly influences detected object, detection sensitivity, the range of linearity and instrument cost.The detecting device of using morely at present mainly contains ultraviolet absorption detector, laser induced fluorescence detector, electric conductivity detector, ampere detector etc.They respectively have relative merits, and on using, ultraviolet absorption detector and electric conductivity detector are more general, but sensitivity is lower; Laser induced fluorescence detector and ampere detector sensitivity are higher, but range of application is narrow.On cost, ultraviolet absorption detector and laser induced fluorescence detector are more expensive, and electric conductivity detector and ampere detector are.In operation, they are all cumbersome.
The purpose of this utility model foot overcomes the shortcoming of prior art, provides one one kinds of manufacture crafts uncomplicated, and is easy to operate during use, sensitivity is higher, range of application is wide, the capillary tube electrophoresis detector of favorable reproducibility.
For achieving the above object, the utility model designs a kind of brand-new high frequency conductance detecting device.
The utility model is according to the high frequency titration principle, and under higher frequency, electrode can place the container outer wall of detected solution, can avoid electrode to contact with detected solution like this.This principle is applied to Capillary Electrophoresis, and its conductance electrode can place the kapillary outer wall, imposes HF voltage to conductance electrode, and when the component stream of separating was through between two electrodes, high-frequency current just changed.In view of the above, can write down Capillary Electrophoresis figure.
The utility model will be further described below in conjunction with drawings and Examples.
Fig. 1 is a structural representation of the present utility model;
Fig. 2 is the utility model electrode structure synoptic diagram;
Fig. 3 implements circuit diagram for the utility model.
With reference to accompanying drawing 1～3, the utility model is by high-frequency oscillating circuits (1), voltage follower (2), electric current--electric pressure converter (3) and high frequency conductance electrode compositions such as (4).The input end of the output termination voltage follower (2) of high-frequency oscillating circuits (1), the input end of the output terminal and the electric current of voltage follower (2)--electric pressure converter (3) connects two utmost points of high frequency conductance electrode (4) respectively, and the output terminal of electric current--electric pressure converter (3) is as the signal output part of this detecting device.
Needs according to the data recordin and procesin system of the capillary electrophoresis apparatus that matches with the utility model, the utility model also can be at electric current--and the output terminal of electric pressure converter (3) is connected to amplifier, and the output terminal of this amplifier is as the signal output part of this detecting device.
The waveform of above-mentioned high-frequency oscillating circuits (1) can be sine wave or square wave, also can be other waveforms, is good with sine or square wave.Oscillation frequency can be good with 20～200kHz from 10kHz to 100MHz.
For reducing circuit noise, improve detection sensitivity, at electric current--electric pressure converter (3) is peripheral or/and whole detecting device periphery is provided with the metallic shield box.
High frequency conductance electrode of the present utility model (4) is two metal tubes, and two metal tubes are coaxial, and tube pitch is good from being 0.5～4mm with 1～3mm.The metal tube internal diameter is slightly larger than the separation capillary external diameter, and kapillary passes through in metal tube.Also can be directly plate two similar metal levels at the kapillary outer wall with the method for electroless plating and make electrode, this method better effects if is a little, but operation is little convenient when using.
The utility model only needs separation capillary is worn in the tubular metal electrode when using Cross, overcome that electrode directly contacts the shortcoming that causes with solution in traditional electric conductivity detector; No Resembling in the electrochemistry class detector electrode installs and fixes and bothers the formality; Need not resemble optics yet Detector carefully scrapes off the protective layer of capillary outer wall like that with cutter. These all are that this practicality is new The advantage of type.
Claims (5)
1, a kind of Capillary Electrophoresis high frequency conductance detecting device, it is characterized in that by high-frequency oscillating circuits (1), voltage follower (2), electric current--electric pressure converter (3) and high frequency conductance electrode (4) are formed, the input end of the output termination voltage follower (2) of high-frequency oscillating circuits (1), the input end of the output terminal and the electric current of voltage follower (2)--electric pressure converter (3) connects two utmost points of high frequency conductance electrode (4) respectively, and the output terminal of electric current--electric pressure converter (3) is as the signal output part of this detecting device.
2, Capillary Electrophoresis high frequency conductance detecting device according to claim 1, it is characterized in that also can be at electric current--and the output terminal of electric pressure converter (3) is connected to amplifier, and the output terminal of this amplifier is as the signal output part of this detecting device.
3, Capillary Electrophoresis high frequency conductance detecting device according to claim 1 is characterized in that the waveform of high-frequency oscillating circuits (1) can be sine wave or square wave, also can be other waveforms, is good with sine or square wave.Oscillation frequency can be good with 20～200kHz from 10kHz to 100MHz.
4, Capillary Electrophoresis high frequency conductance detecting device according to claim 1 is characterized in that at electric current--electric pressure converter (3) is peripheral or/and whole detecting device periphery is provided with the metallic shield box.
5, Capillary Electrophoresis high frequency conductance detecting device according to claim 1 is characterized in that high frequency conductance electrode (4) is two metal tubes, and two metal tubes are coaxial, and tube pitch is good from being 0.5～4mm with 1～3mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99256001 CN2414415Y (en) | 1999-12-17 | 1999-12-17 | Capillary tube electrophoresis high-frequency conductivity tester |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99256001 CN2414415Y (en) | 1999-12-17 | 1999-12-17 | Capillary tube electrophoresis high-frequency conductivity tester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2414415Y true CN2414415Y (en) | 2001-01-10 |
Family
ID=34039225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 99256001 Expired - Fee Related CN2414415Y (en) | 1999-12-17 | 1999-12-17 | Capillary tube electrophoresis high-frequency conductivity tester |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2414415Y (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1295499C (en) * | 2001-11-20 | 2007-01-17 | 生命扫描有限公司 | Determination of sample volume sufficiency in biosensor |
| CN108593748A (en) * | 2018-01-26 | 2018-09-28 | 南京溯远基因科技有限公司 | capillary and DNA sequencer |
-
1999
- 1999-12-17 CN CN 99256001 patent/CN2414415Y/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1295499C (en) * | 2001-11-20 | 2007-01-17 | 生命扫描有限公司 | Determination of sample volume sufficiency in biosensor |
| CN108593748A (en) * | 2018-01-26 | 2018-09-28 | 南京溯远基因科技有限公司 | capillary and DNA sequencer |
| CN108593748B (en) * | 2018-01-26 | 2024-04-30 | 南京溯远基因科技有限公司 | Capillary and DNA sequencer |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7842174B2 (en) | Electrochemical chip with miniaturized sensor array | |
| AU3791995A (en) | Apparatus for identifying container components using electrical conductivity | |
| EP0236434A1 (en) | Wave shape chemical analysis apparatus and method. | |
| CN2414415Y (en) | Capillary tube electrophoresis high-frequency conductivity tester | |
| CN115452757B (en) | CO based on sensor 2 Concentration monitoring system | |
| CN111751625B (en) | Non-contact conductivity measuring device and method based on LC circuit | |
| US20220178866A1 (en) | Method for measuring semiconductor gas sensor based on virtual alternating current impedance | |
| CN106370635A (en) | Method, equipment and system for quantitatively detecting content of polar ingredients in edible oil | |
| CN204718996U (en) | The direct insertion multiparameter water quality analyzer of microelectrode | |
| CN206161582U (en) | Electric capacity type soil moisture sensor | |
| CN108269729A (en) | A kind of plate armature High-Field asymmetric waveform ion mobility spectrometry combined instrument | |
| Leung et al. | Determination of arsenic in polluted waters by differential pulse anodic-stripping voltammetry | |
| JPH07280691A (en) | Liquid leakage detector | |
| CN201255648Y (en) | Liquid level detecting device | |
| CN204556052U (en) | A kind of liquid level intelligent-induction circuit and device thereof | |
| CN2354140Y (en) | Plasma ion-energy measuring and analyzing instrument | |
| CN219742702U (en) | Peak-hold blood sugar ac impedance measuring device | |
| CN2600820Y (en) | Internal resistance of source measuring instrument | |
| CN214041551U (en) | Open short circuit terminal of high-frequency impedance analyzer | |
| CN213068986U (en) | Automatic measuring and printing system for oscilloscope probe | |
| CN111104277B (en) | Electronic pen testing device and method | |
| Williams et al. | Hand-held instrumentation for environmental monitoring | |
| CN108508083A (en) | The intelligent heavy metal ion specific detection instrument for effect of being shaken based on magnetic | |
| CN211741077U (en) | Fluorescence detection circuit and fluorescence detection equipment | |
| CN117871622A (en) | Simple heavy metal detector and detection method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |