CN221359946U

CN221359946U - Liquid separating equipment

Info

Publication number: CN221359946U
Application number: CN202323578807.7U
Authority: CN
Inventors: 丁晓东; 程寿玲; 方纯
Original assignee: SANGON BIOTECH (SHANGHAI) CO Ltd
Current assignee: Nanjing Qisong Biotechnology Co.,Ltd.
Priority date: 2023-12-26
Filing date: 2023-12-26
Publication date: 2024-07-19
Anticipated expiration: 2033-12-26

Abstract

The utility model provides liquid separation equipment, and belongs to the technical field of split charging. The liquid separating device comprises an operation table, a sample storage rack, a mechanical arm, a first liquid shifter, a separating rack, an opening and closing cover device, an industrial personal computer and at least one photometer, wherein the sample storage rack, the mechanical arm, the first liquid shifter, the separating rack, the opening and closing cover device, the industrial personal computer and the at least one photometer are arranged on the operation table; a plurality of first mounting grooves for accommodating mother liquor pipes are formed in one side of the sample storage rack, which is away from the operation table; the output end of the mechanical arm is provided with a clamping part for clamping the first liquid transfer device and a grabbing part for grabbing the mother liquid pipe; the first pipettor can suck or discharge the sample in the mother liquor pipe; the split charging rack is provided with a plurality of first mounting holes for accommodating centrifuge tubes; the opening and closing cover device is provided with an installation position for accommodating the mother liquor pipe; the first pipettor, the photometer and the mechanical arm are respectively and electrically connected with the industrial personal computer. The liquid separating device provided by the utility model not only can improve the accuracy of quantitative liquid separation, but also can improve the liquid separating efficiency.

Description

Liquid separating equipment

Technical Field

The utility model relates to the technical field of split charging, in particular to liquid separating equipment.

Background

The existing pipetting workstations in the market only perform single pipetting and cannot perform quantitative pipetting of a micro spectrophotometer. At present, quantitative liquid separation is carried out by manual sample separation, so that the manual sample separation has high error rate, the split charging difference is easy to occur, the split charging speed is low, and the split charging efficiency is low.

Disclosure of utility model

In view of the above, the present utility model aims to overcome the defects in the prior art, and provide a liquid separation device.

The utility model provides the following technical scheme: the liquid separating device comprises an operation table, a sample storage rack, a mechanical arm, a first liquid shifter, a separating rack, an opening and closing cover device, an industrial personal computer and at least one photometer, wherein the sample storage rack, the mechanical arm, the first liquid shifter, the separating rack, the opening and closing cover device, the industrial personal computer and the at least one photometer are arranged on the operation table;

a plurality of first mounting grooves for accommodating mother liquor pipes are formed in one side, away from the operation table, of the sample storage rack;

The output end of the mechanical arm is provided with a clamping part for clamping the first liquid transfer device and a grabbing part for grabbing the mother liquid pipe;

The first pipettor can suck or discharge the sample in the mother liquor pipe;

The split charging rack is provided with a plurality of first mounting holes for accommodating centrifuge tubes;

The opening and closing cover device is provided with an installation position for accommodating the mother liquor pipe;

the first pipettor, the photometer and the mechanical arm are respectively and electrically connected with the industrial personal computer.

In some embodiments of the utility model, a first carrying case is provided on one side of the sample storage rack, the first carrying case defining a plurality of first receiving slots, each of the first receiving slots having a first tip disposed therein.

Further, a second bearing box is arranged on one side of the first bearing box, the second bearing box defines a plurality of second accommodating grooves, and a second suction head is placed in each second accommodating groove;

the capacity of the first tip is different from the capacity of the second tip.

Further, the liquid separating device comprises a second liquid dispenser;

the operation table is provided with a support frame for bearing the first liquid dispenser and the second liquid dispenser;

the output end of the first liquid dispenser is used for being connected with the first suction head, and the output end of the second liquid dispenser is used for being connected with the second suction head.

Further, the operation table is provided with a third accommodating groove for accommodating the first suction head and the second suction head.

Further, the opening and closing cover device comprises a supporting seat and a driving device;

At least one installation position is arranged on one side, away from the operation table, of the supporting seat;

The driving device is arranged on one side of the supporting seat, and the output end of the driving device is provided with a movable plate for opening or closing the tube cover of the mother liquid tube.

Further, the grabbing part comprises a pump body and at least one sucker, and the sucker is communicated with the output end of the pump body.

Further, the split charging frame comprises at least one bearing disc, and a plurality of first mounting holes for bearing the centrifugal tubes are formed in the bearing disc.

Further, the sample storage rack defines a plurality of tool bars, and each tool bar is provided with a plurality of first mounting grooves which are spaced apart.

Further, a fluid replacement table is arranged on the operation table, and at least one second mounting groove for containing diluent is formed in one side, away from the operation table, of the fluid replacement table.

Embodiments of the present utility model have the following advantages: the mechanical arm is controlled by the industrial personal computer to move, grab, place, rotate, position and the like, and the mechanical arm drives the sample in the mother liquor pipe of the first liquid transfer device to transfer or quantitatively divide the sample, and the first liquid transfer device extracts and divides the sample in the mother liquor pipe into centrifuge tubes on the dividing rack according to the dividing volume set in the industrial personal computer, so that the accuracy of quantitative liquid division can be improved, and the liquid division efficiency can be improved.

In order to make the above objects, features and advantages of the present utility model more comprehensible, preferred embodiments accompanied with figures are described in detail below.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings that are needed in the embodiments will be briefly described below, it being understood that the following drawings only illustrate some embodiments of the present utility model and therefore should not be considered as limiting the scope, and other related drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic view of a liquid separation device according to some embodiments of the present utility model;

fig. 2 shows an enlarged view of the portion a in fig. 1;

Fig. 3 is a schematic structural view of another view of a liquid separation device according to some embodiments of the present utility model.

Description of main reference numerals:

100-operating platform; 110-a third accommodation groove; 200-sample storage rack; 210-tool bars; 220-mother liquor pipe; 300-a mechanical arm; 310-clamping part; 320-a gripping portion; 321-a pump body; 322-sucking disc; 400-first pipettor; 500-separating and loading frames; 510—a carrier tray; 600-opening and closing cover device; 610-a support base; 620-driving means; 630-a movable plate; 700-industrial personal computer; 800-photometer; 900-a first carrier box; 1000-a first suction head; 1100-a second carrier box; 1200-second tip; 1300-a fluid infusion station; 1310-a second mounting slot; 1400-centrifuge tube; 1500-second pipettor; 1600-supporting frame.

Detailed Description

Embodiments of the present utility model are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below by referring to the drawings are illustrative only and are not to be construed as limiting the utility model.

It will be understood that when an element is referred to as being "fixed to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. In contrast, when an element is referred to as being "directly on" another element, there are no intervening elements present. The terms "vertical," "horizontal," "left," "right," and the like are used herein for illustrative purposes only.

In the present utility model, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communicated with the inside of two elements or the interaction relationship of the two elements. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.

Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. In the description of the present utility model, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this utility model belongs. The terminology used in the description of the templates herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the utility model. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.

As shown in fig. 1 to 3, some embodiments of the present utility model provide a liquid dispensing apparatus, which is mainly applied to dispensing liquid, so as to improve the quality and efficiency of dispensing liquid, and improve the accuracy of dispensing liquid.

The liquid separating device comprises an operation table 100, and a sample storage rack 200, a mechanical arm 300, a first liquid transferring device 400, a split charging rack 500, an opening and closing cover device 600, an industrial personal computer 700 and at least one photometer 800 which are arranged on the operation table 100 at intervals.

It is understood that the number of photometers 800 may be one, two or more than two, and may be specifically set according to practical situations.

In this embodiment, the number of photometers 800 is two. By providing a plurality of photometers 800, the detection efficiency of the sample per unit time is improved.

Illustratively, when one of the two photometers 800 is finished detecting a sample, the photometer 800 is required to be cleaned and dried in order to detect the next sample again, thereby ensuring the accuracy of the photometer 800 for detecting each sample. When one photometer 800 is in the process of cleaning and drying, a sample can be detected in the other photometer 800, so that the smoothness of detection is ensured, the occurrence of a detection idle stage is avoided, and the detection efficiency can be improved.

Wherein, a plurality of first mounting grooves for accommodating the mother liquor pipe 220 are provided on a side of the sample storage rack 200 facing away from the operation table 100, so as to provide support and limit for the mother liquor pipe 220 through the first mounting grooves, so as to ensure stability of the mother liquor pipe 220 in the first mounting grooves.

It is understood that the number of the first mounting grooves may be specifically set according to actual situations.

In addition, the output end of the mechanical arm 300 is provided with a clamping portion 310 for clamping the first pipette 400, and it should be noted that the output end of the mechanical arm 300 provided by the utility model can rotate 360 degrees, and the mechanical arm 300 body can rotate, so that the first pipette 400 clamped at the clamping portion 310 can conveniently pipette and split samples.

The output end of the mechanical arm 300 is further provided with a gripping portion 320 for gripping the mother liquor tube 220, so that the mother liquor tube 220 placed in the sample storage rack 200 is gripped by the gripping portion 320, and a part of the mother liquor tube 220 in the sample storage rack 200 is transferred to an installation position of the open-close cover device 600 through the mechanical arm 300, wherein the installation position is used for accommodating the mother liquor tube 220, so that the sample in the mother liquor tube 220 in the installation position can be detected and sub-packaged.

In this embodiment, the first pipettor 400 is capable of aspirating or expelling the sample from the mother liquor tube 220. Specifically, the cover on the mother liquid pipe 220 placed at the installation position is opened by the opening and closing cover device 600, the output end of the first pipettor 400 can absorb a part of samples in the mother liquid pipe 220, the first pipettor 400 absorbed with the samples is moved into the photometer 800 by the mechanical arm 300, the absorbed samples are extruded by the first pipettor 400, the samples are dropped into the photometer 800, the samples are detected by the photometer 800, the detected results are uploaded to the MES system of the industrial personal computer 700, and the detection results are judged by the MES system.

After the sample detected by the photometer 800 is qualified, a control instruction is sent to the mechanical arm 300 and the first pipettor 400 by the industrial personal computer 700, so that the first pipettor 400 is controlled to repeatedly move back and forth between the opening and closing cover device 600 and the split charging frame 500 by the mechanical arm 300, and meanwhile, the sample in the mother liquor tube 220 which is qualified in the opening and closing cover device 600 is quantitatively transferred to the centrifuge tube 1400 arranged in the first mounting hole of the split charging frame 500 by the first pipettor 400, so that split charging of the liquid in the mother liquor tube 220 is realized.

It will be appreciated that the number of the first mounting holes provided in the split charging rack 500 is plural, that is, the number of the first mounting holes may be specifically set according to practical situations, and the centrifuge tube 1400 may be placed in the first mounting holes, and the first mounting holes may provide a limiting and fixing effect on the centrifuge tube 1400, so as to meet the split charging requirement on the sample in the mother liquor tube 220.

In this embodiment, the first pipette 400, the photometer 800, and the robot 300 are electrically connected to the industrial personal computer 700, respectively.

Specifically, the photometer 800 is connected with the industrial personal computer 700, so that the photometer 800 sends the detected result to the MES system of the industrial personal computer 700, and the detection result is judged through the MES system.

In addition, it should be noted that, in some embodiments of the present utility model, the first pipette 400 is a single-channel or multi-channel bluetooth pipette, that is, the first pipette 400 can be connected to the industrial personal computer 700 through bluetooth, so that the first pipette 400 can be remotely controlled through the MES system. Specifically, the first pipette 400 may be NanoPhotometer N or 60 in sizeN120。

Specifically, the model of the robot arm 300 is CRB 15000. The MES system of the industrial personal computer 700 sends out a control instruction to the mechanical arm 300, so that the mechanical arm 300 moves, grabs, places, rotates, positions and the like according to the control instruction, quantitative liquid distribution of a sample is realized, and the accuracy and the liquid distribution efficiency of quantitative liquid distribution are improved.

In some embodiments of the present utility model, as shown in fig. 1 and 2, the sample storage rack 200 defines a plurality of tool bars 210, and each of the tool bars 210 is provided with a plurality of spaced apart first mounting grooves.

The plurality of tool bars 210 are sequentially and linearly arranged along the first direction, and the number of the tool bars 210 can be specifically set according to practical situations.

In addition, the number of the first installation grooves provided on the tool bar 210 may be specifically set according to actual situations.

It will be appreciated that by increasing the number of tool bars 210 and first mounting slots, the capacity of the sample storage rack 200 to accommodate the mother liquor tube 220 is increased.

As shown in fig. 2 and 3, in some embodiments of the present utility model, the gripping portion 320 includes a pump body 321 and at least one suction cup 322, the suction cup 322 being in communication with an output end of the pump body 321. The number of the suction cups 322 may be one, two or more than two, and may be specifically set according to practical situations.

It can be appreciated that the number of the mother liquor pipes 220 placed in the sample storage rack 200 is increased by increasing the number of the dishes to raise the number of the mother liquor pipes per unit time by the grip part 320.

The pump body 321 is electrically connected to the mechanical arm 300, so as to control the start or stop of the pump body 321 by the mechanical arm 300.

Specifically, when the industrial personal computer 700 sends a grabbing instruction to the mechanical arm 300, the mechanical arm 300 receives the grabbing instruction and controls the grabbing part 320 to move to the sample storage rack 200, when the sucker 322 corresponds to the mother liquor pipe 220, the pump body 321 is started, the mother liquor pipe 220 is sucked through the sucker 322, and the mother liquor pipe 220 adsorbed on the sucker 322 is moved to the installation position of the opening and closing cover device 600 through the mechanical arm 300, so that the transfer of the mother liquor pipe 220 is realized.

It should be noted that, when the plurality of suction cups 322 is provided, the distance between adjacent suction cups 322 is equal to the distance between two adjacent mother liquid tubes 220 in the sample storage rack 200, and therefore, each suction cup 322 can correspond to one mother liquid tube 220, so as to improve the accuracy and stability of the grabbing portion 320 grabbing the mother liquid tube 220.

As shown in fig. 1 and 3, in some embodiments of the present utility model, a first carrying case 900 is provided at one side of the sample storage rack 200, and the first carrying case 900 defines a plurality of first receiving grooves, in each of which a first suction head 1000 is placed.

The arrangement of the plurality of first accommodating grooves in the first carrying case 900 may be any one of a matrix arrangement, a linear arrangement, a spiral arrangement, or a combination of two or more thereof.

Through increasing the quantity of first holding tank to increase the bearing capacity of first carrier box 900 to first suction head 1000, so that first suction head 1000 is changed to first pipettor 400, so that through the collection of first pipettor 400 to different samples, avoid appearing the condition of sample cross contamination, in order to guarantee the accuracy that photometer 800 detected the sample, and through first pipettor 400 to sample split charging quality.

Optionally, in some embodiments of the present utility model, a second carrying case 1100 is disposed on one side of the sample storage rack 200, and the second carrying case 1100 defines a plurality of second receiving grooves, and each of the second receiving grooves has a second suction head 1200 disposed therein.

In addition, the arrangement of the plurality of second receiving grooves in the second cassette 1100 may be any one or a combination of two or more of a matrix arrangement, a linear arrangement, and a spiral arrangement.

It should be noted that, the capacity of the first pipette tip 1000 is different from the capacity of the second pipette tip 1200, so that the first pipette 400 can replace the first pipette tip 1000 or the second pipette tip 1200 according to different dispensing requirements, so as to further improve the dispensing efficiency of the sample.

As shown in fig. 1 to 3, in some embodiments of the present utility model, the cover opening and closing apparatus 600 includes a support base 610 and a driving device 620.

Wherein, at least one mounting position is disposed on a side of the support base 610 facing away from the console 100, that is, the number of mounting positions may be one, two or more than two arbitrary values, which may be specifically set according to practical situations.

In this embodiment, the number of the installation sites is equal to or greater than the number of the suction cups 322, so that each of the mother liquor pipes 220 sucked on the suction cups 322 can be placed on the installation site.

In addition, the driving device 620 is disposed at one side of the support base 610, and a movable plate 630 for opening or closing the tube cover of the mother liquor tube 220 is disposed at the output end of the driving device 620, that is, the tube cover of the mother liquor tube 220 placed on the installation site can be opened or closed by the driving device 620.

When the mother liquor pipe 220 is placed on the installation position, the movable plate 630 is driven by the driving device 620, the movable plate 630 is abutted against the pipe cover of the mother liquor pipe 220, and the pipe cover of the mother liquor pipe 220 is opened, so that the first pipettor 400 can transfer a part of samples in the mother liquor pipe 220 to the photometer 800, and the samples are detected by the photometer 800. In addition, the first pipetter 400 can also dispense the sample in the mother liquor pipe 220 into the centrifuge tube 1400 on the dispensing rack 500, thereby dispensing the sample in the mother liquor pipe 220.

After the sample in each mother liquor tube 220 at the installation position is completely split by the mechanical arm 300 and the first pipettor 400, the movable plate 630 is controlled by the driving device 620 to close the tube cover of the mother liquor tube 220, so as to prevent the sample from being sprayed out of the mother liquor tube 220 or prevent the sample in the mother liquor tube 220 from volatilizing during the moving process.

As shown in fig. 1 and 3, in some embodiments of the present utility model, the operation panel 100 is provided with a fluid-filling table 1300, and a side of the fluid-filling table 1300 facing away from the operation panel 100 is provided with at least one second mounting groove 1310 for receiving a diluent.

When the result of the sample detection of the photometer 800 is greater than the preset concentration, the concentration of the sample in the mother liquor pipe 220 is higher, and at this time, the diluent in the second installation groove 1310 is added to the mother liquor pipe 220 corresponding to the installation position by the first pipette 400, and the sample in the mother liquor pipe 220 is diluted, so as to reduce the concentration of the sample in the mother liquor pipe 220, so that the concentration of the sample in the mother liquor pipe 220 can meet the split-charging concentration.

As shown in fig. 1 and 3, in some embodiments of the present utility model, the sub-packaging rack 500 includes at least one carrying tray 510, where the carrying tray 510 is provided with a plurality of first mounting holes spaced apart from each other, and the first mounting holes are used for limiting the centrifuge tube 1400, that is, the centrifuge tube 1400 can be clamped in the first mounting holes, so as to ensure stability of the centrifuge tube 1400 in the first mounting holes.

The connection manner between the carrying tray 510 and the sub-packaging rack 500 includes any one of clamping connection, bolting connection, bonding, magnetic attraction connection or welding, and can be specifically set according to practical situations.

In this embodiment, the carrying tray 510 is detachably connected to the split charging rack 500, so that the centrifuge tubes 1400 after split charging on the carrying tray 510 can be transferred.

In addition, the number of the first mounting holes provided on the carrying tray 510 may be specifically set according to practical situations, and it may be understood that by increasing the number of the first mounting holes, the carrying capacity of the carrying tray 510 to the centrifuge tube 1400 is improved, so that the split charging capacity of the sample in the mother liquor tube 220 is improved, and the split charging requirement of the staff on the sample is met.

As shown in fig. 1 and 2, in some embodiments of the utility model, the pipetting device includes a second pipette 1500.

The console 100 is provided with a support 1600 for carrying the first and second pipettes 400 and 1500, i.e., the first and second pipettes 400 and 1500 are placed on the support 1600, so as to provide supporting and limiting functions for the first and second pipettes 400 and 1500 through the support 1600.

Specifically, a first limiting hole and a second limiting hole are formed in the support frame 1600 at intervals, and a part of the first pipette 400 penetrates through the first limiting hole to form a clamping connection with the hole wall of the first limiting hole. A portion of the second pipette 1500 passes through the second limiting hole and forms a clamping connection with the hole wall of the second limiting hole.

The output end of the first pipette 400 is connected to the first tip 1000, and the output end of the second pipette 1500 is connected to the second tip 1200.

Through setting up first pipettor 400 and second pipettor 1500 to the sample to different partial shipment demands carries out the partial shipment, promotes the partial shipment efficiency of liquid dispensing equipment to the sample.

As shown in fig. 1 and 3, in some embodiments of the present utility model, the console 100 is provided with a third receiving groove 110 for receiving the first and second pipette tips 1000 and 1200, and the first and second pipette tips 1000 and 1200 (herein, the first and second pipette tips 1000 and 1200 having sucked in the sample) after use are received for recycling by providing the third receiving groove 110.

Any particular values in all examples shown and described herein are to be construed as merely illustrative and not a limitation, and thus other examples of exemplary embodiments may have different values.

It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further definition or explanation thereof is necessary in the following figures.

The above examples merely represent a few embodiments of the present utility model, which are described in more detail and are not to be construed as limiting the scope of the present utility model. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the utility model, which are all within the scope of the utility model.

Claims

1. The liquid separating device is characterized by comprising an operation table, a sample storage rack, a mechanical arm, a first liquid shifter, a separating rack, an opening and closing cover device, an industrial personal computer and at least one photometer, wherein the sample storage rack, the mechanical arm, the first liquid shifter, the separating rack, the opening and closing cover device, the industrial personal computer and the at least one photometer are arranged on the operation table;

The first pipettor can suck or discharge the sample in the mother liquor pipe;

2. The dispensing apparatus of claim 1 wherein a first carrying cassette is provided on one side of the sample storage rack, the first carrying cassette defining a plurality of first receiving slots, each of the first receiving slots having a first tip disposed therein.

3. The liquid separation apparatus according to claim 2, wherein a second carrying case is provided on one side of the first carrying case, the second carrying case defining a plurality of second accommodating grooves, each of the second accommodating grooves having a second suction head disposed therein;

the capacity of the first tip is different from the capacity of the second tip.

4. A liquid dispensing device as claimed in claim 3, wherein the liquid dispensing device comprises a second pipettor;

5. A liquid dispensing apparatus according to claim 3, wherein the console is provided with a third receiving groove for receiving the first and second suction heads.

6. The liquid separating apparatus as claimed in any one of claims 1 to 5, wherein the opening and closing cover means comprises a support base and a driving means;

7. The liquid dispensing apparatus according to any one of claims 1 to 5, wherein the gripping portion comprises a pump body and at least one suction cup, the suction cup being in communication with an output end of the pump body.

8. The dispensing apparatus of any one of claims 1 to 5 wherein the dispensing rack comprises at least one carrier tray having a plurality of first mounting holes for carrying the centrifuge tubes.

9. The dispensing apparatus of any one of claims 1 to 5 wherein the sample storage rack defines a plurality of tool bars, each of the tool bars having a plurality of spaced apart first mounting slots.

10. The liquid separation apparatus according to any one of claims 1 to 5, wherein a liquid replenishment table is provided on the operation table, and at least one second mounting groove for accommodating a diluent is provided on a side of the liquid replenishment table facing away from the operation table.