CN221013310U

CN221013310U - Wearable ultrasonic Doppler blood flow monitoring system

Info

Publication number: CN221013310U
Application number: CN202321883876.6U
Authority: CN
Inventors: 徐丽霞; 王玉玫
Original assignee: Suzhou Xisheng Technology Co ltd
Current assignee: Suzhou Xisheng Technology Co ltd
Priority date: 2023-07-17
Filing date: 2023-07-18
Publication date: 2024-05-28
Anticipated expiration: 2033-07-18

Abstract

The utility model discloses a wearable ultrasonic Doppler blood flow monitoring system which comprises an ultrasonic sensor and a host, wherein the ultrasonic sensor comprises a pcb substrate, a plurality of groups of multi-array-element ultrasonic transducers and a flexible packaging layer, the pcb substrate is communicated with the host, each group of multi-array-element ultrasonic transducers comprises a plurality of ultrasonic transducers which are distributed at intervals and form different angles with the pcb substrate, and each group of multi-array-element ultrasonic transducers at least comprises an ultrasonic transducer Ux with an angle of zero degrees, and ultrasonic transducers Ua and ultrasonic transducers Ub which are positioned at two ends of the ultrasonic transducer Ux and distributed at intervals. The utility model can implement real-time monitoring of human blood flow information in a continuous Doppler mode and a pulse Doppler mode, can overcome the defects of large volume, high professional technical requirements, complex operation and the like of the traditional ultrasonic Doppler equipment, and has the advantages of simple structure, low cost, portability, convenience and the like.

Description

Wearable ultrasonic Doppler blood flow monitoring system

Technical Field

The utility model belongs to the field of medical appliances, and particularly relates to a wearable ultrasonic Doppler blood flow monitoring system.

Background

The Doppler index of blood flow has very wide and important requirements and values in clinic, and is an important index of a plurality of diseases and physiological characteristics. The ultrasonic Doppler and technology refers to a method for detecting the blood flow of moving organs and blood vessels by utilizing the Doppler effect principle, and is also the most main means for clinically obtaining the blood flow Doppler at present, and the method is divided into continuous Doppler and pulse Doppler according to the working state.

For continuous doppler, which uses two ultrasound transducers, one of which continuously transmits ultrasound and the other of which continuously receives echoes, the method has a very high velocity resolution, and can detect very high velocity blood flow, which is a major advantage thereof, and the most significant disadvantage thereof is the lack of distance resolution.

Pulsed Doppler is the transmission and reception of ultrasound waves by the same ultrasound transducer. Because the depth gating (or distance gating) technology is adopted, the fixed point blood flow measurement can be carried out, so that the method has high distance resolution and can also accurately analyze the property of the fixed point blood flow. Since the maximum display frequency of pulse wave doppler is limited by the pulse repetition frequency, aliasing is likely to occur when detecting high-speed blood flow.

At present, the clinically used ultrasonic Doppler system mainly uses a B-ultrasonic trolley, and although the clinical diagnosis can meet the requirements of clinic, the ultrasonic Doppler system has various limitations in real-time monitoring, home detection and the like, and cannot meet the use requirements of long time span or frequent blood flow monitoring, so that how to miniaturize the ultrasonic Doppler detection equipment and even wear the ultrasonic Doppler detection equipment to meet the requirements of daily monitoring becomes a hot spot of current research.

However, there are many existing wearable ultrasound doppler patents, the most similar methods and devices being listed: application number: CN201820488946.0, patent name: a wearable ultrasonic Doppler blood flow detector is disclosed, which is divided into upper and lower limb detection. Application number: CN202111135992.5, patent name: a wearable ultrasonic Doppler blood flow detector and a detection method, the invention relates to clothing type wearing. Application number: KR1020070114541a, portable device for measuring blood flow, watch type ultrasound to detect doppler.

In summary, the ultrasonic Doppler blood flow detection device has the following defects: 1. the equipment has large volume and high price; 2. needs operation by clinical professional medical staff and cannot be used for household; 3. the wearing is impossible, and the long-time monitoring is performed; 4. pulse Doppler and continuous Doppler detection cannot be performed simultaneously; 5. there is no blood pressure information.

Disclosure of Invention

The utility model aims to overcome the defects of the prior art and provide an improved wearable ultrasonic Doppler blood flow monitoring system.

According to the ultrasonic Doppler blood flow monitoring system, a plurality of groups of ultrasonic transducers which are arranged in a specific manner are arranged in the flexible substrate to form the flexible and adhesive wearable probe and the special processing system, so that system equipment can be used for pulse Doppler detection and continuous Doppler detection, the system has the characteristics of miniaturization and wearability, and can monitor blood flow information of a human body, such as flow velocity, blood flow pulsation index, blood pressure and the like, in real time, and the requirements of multi-scene application are met.

In order to solve the technical problems, the utility model adopts the following technical scheme: the utility model provides a wearing formula ultrasonic Doppler blood flow monitoring system, it includes ultrasonic sensor, the host computer, ultrasonic sensor includes rectangular form and is flexible pcb base plate, the multiunit multiset element ultrasonic transducer of interval distribution on pcb base plate, and encapsulation is at multiunit multiset element ultrasonic transducer surface and can laminate the flexible encapsulation layer of skin, wherein pcb base plate is linked together with the host computer, every multiunit element ultrasonic transducer includes interval distribution and a plurality of ultrasonic transducers of unequal angle that forms with pcb base plate, every multiunit element ultrasonic transducer includes at least that an angle is zero degree ultrasonic transducer Ux, ultrasonic transducer Ua and ultrasonic transducer Ub that are located ultrasonic transducer Ux both ends and interval distribution, wherein ultrasonic transducer Ux can transmit ultrasonic wave and receive ultrasonic wave, one of ultrasonic transducer Ua and ultrasonic transducer Ub transmits ultrasonic wave, another receives ultrasonic wave.

Preferably, each group of multi-array element ultrasonic transducers comprises ultrasonic transducers U1, U2, U3, U4 and U5 which are distributed in sequence, wherein U3 is an ultrasonic transducer Ux which is positioned in the middle and has an angle of zero degrees, two ultrasonic transducers Ua are respectively U1 and U2, and two ultrasonic transducers Ub are respectively U4 and U5. That is, each set of transducers consists of 5 transducers, 5 transducers being at a fixed angle, θ0, θ1,0, θ2, θ3, to the bottom pcb circuit.

Further, each group of ultrasonic transducers U1, U2, U3, U4, U5 forms the same angle with the pcb substrate.

According to one specific implementation and preferred aspect of the utility model, the backing layer of each ultrasonic transducer is an electrical conductor, the pcb substrate is formed with a bonding pad with a positive electrode and a negative electrode, the electrical conductor is connected to the bonding pad through conductive glue or conductive wedge-shaped blocks and is communicated with the negative electrode of the bonding pad, the positive electrode of the ultrasonic transducer is communicated with the positive electrode of the bonding pad through conductive lines, one end of the pcb substrate forms a connector end, and the connector end is communicated with the host. Thus, the circuit conduction installation of the ultrasonic transducer is convenient.

The backing layer is a conductive material such as silver paste. Or the low frequency transducer has no backing. Electrodes such as gold, silver, aluminum and the like are plated on two sides of the working layer material of the transducer.

Preferably, the conductive paste is silver paste.

Each transducer is connected with the flexible PCB circuit board at the bottom, and the specific operation of the transducers can be controlled through the gating module of the host.

The transducer negative electrode (conductive backing) is directly adhered to the negative electrode pad of the pcb substrate by a conductive adhesive. In order to control the size and structure of the circuit, all the negative electrode bonding pads are conducted to form a common ground circuit, and then the positive electrode of the transducer is connected to the positive electrode bonding pad of the pcb substrate by means of bonding wires/gold wire welding and the like. All electrode pads at one end of the pcb substrate form a connector end and are connected to a host system through the connector end. In particular, to enhance the performance of flexible bending, the wires in the pcb substrate are curved or serpentine in shape.

And the plurality of groups of multi-array element ultrasonic transducers are arranged in a linear array or an area array. That is, the whole flexible probe is formed by arranging a plurality of groups of transducers, and the transducers in the probe can be arranged in a linear array or an area array.

Preferably, the ultrasonic transducer can be a piezoelectric ultrasonic transducer, a piezoelectric composite ultrasonic probe, a capacitive ultrasonic probe or a film ultrasonic probe, the working frequency range can be 1 MHz-15 MHz, and the outer diameter size is 0.1 mm-2 mm. That is, the ultrasonic transducers used may be piezoelectric ultrasonic transducers such as PZT/PMN-PT, piezoelectric composite ultrasonic probes such as 1-3 piezoelectric composites, capacitive ultrasonic probes such as CMUT, membrane type ultrasonic probes such as PVDF/AlN, or the like.

In this example, the 5 transducers in each set of probes, which constitute the plurality of sets of flexible ultrasonic transducers, have the same center of operation frequency, but the center of operation frequencies of the transducers of different sets may be different. Depending on the need to monitor target depth, resolution and sensitivity.

According to yet another specific and preferred aspect of the present utility model, the flexible encapsulation layer is a hydrogel, a silicone gel, a rubber or an adhesive tape. After the transducer is bonded to the pcb, the adhesive is integrally poured. The adhesive body mainly plays a role in protecting the transducer and pcb circuit and adhering to the skin of a human body.

That is, the flexible packaging layer not only can protect the ultrasonic transducer and the circuit of the flexible pcb, but also can adhere to the object to be detected, in this example, PDMS (polydimethylsiloxane) is used, which is an organosilicon, and has the characteristics of low cost, simple use, good adhesion with a silicon wafer, good chemical inertness, and the like, so that the flexible packaging layer becomes a polymer material widely applied to the fields of microfluidics and the like.

In addition, the host comprises a high-voltage pulse excitation module, a gating circuit, a receiving unit, a control unit and a display unit, wherein the gating circuit is communicated with the pcb substrate, and the number of the paths gated by the gating circuit is at least two. The gating circuit primarily enables gating of the working transducers, thereby reducing the complexity of the system without having to equip each transducer with separate excitation and receiving circuits. To ensure the detection of continuous pulse doppler, at least 2 transducers can be operated simultaneously.

Preferably, the display unit comprises a display module, an information processing module and an information transmission module, wherein the information transmission module is communicated with the user terminal through a wire or/and a wireless. That is, the information transmission module can be a mobile battery module added with wireless transmission such as wifi, bluetooth and the like, and conveniently transmits the collected and processed data to the user terminal.

The high-voltage pulse excitation module generates high-voltage pulses with the amplitude of 20-600V and the pulse width of less than 10us. The ultrasonic probe is driven to work by the high-voltage pulse excitation voltage generated in the way.

The receiving unit mainly realizes low-noise amplification, filtering, gain and sampling of echo signals and mainly comprises a low-noise amplifier LNA, a band-pass filter, an adjustable gain TGC and an analog-to-digital conversion chip ADC.

The control unit mainly controls the work of each part, including the control of the on-off state of each path of the gating switch, the time sequence of the exciting circuit, the gain of TGC, the processing of echo signals such as Fourier transformation, etc., and is mainly composed of a single chip microcomputer for portable miniaturization.

In addition, in order to wear portably and data looks over, can add wireless transmission such as wifi, bluetooth etc. in the host system, mobile battery module, the convenient data transmission that will gather processing goes to the terminal.

The user terminal is connected with the information transmission module in a wired and wireless mode, and the main functions of the user terminal include post-processing, displaying, alarming and the like of data. The user terminal can be a smart phone, a tablet computer, a mobile computer, a smart television and the like.

Due to the implementation of the technical scheme, compared with the prior art, the utility model has the following advantages:

The utility model utilizes the wearable multi-array element flexible ultrasonic sensor and the Doppler technology, can realize the real-time monitoring of human blood flow information in a continuous Doppler mode and a pulse Doppler mode, can overcome the defects of large volume, high professional technical requirements, complex operation and the like of the traditional ultrasonic Doppler equipment, has the advantages of simple structure, low cost, portability, wearing, convenience and the like, and is expected to be applied to the clinical and personal monitoring fields.

Drawings

Fig. 1 is a schematic front view of a wearable ultrasound doppler blood flow monitoring system of the present utility model;

FIG. 2 is an enlarged schematic diagram of the structure of the host in FIG. 1;

FIG. 3 is an enlarged schematic view of the structure of the ultrasonic sensor of FIG. 1;

Wherein: 1. a host; 10. a high voltage pulse excitation module; 11. a gating circuit; 12. a receiving unit; 13. a control unit; 14. a display unit; 140. a display module; 141. an information processing module; 142. an information transmission module; 2. an ultrasonic sensor; 20. a pcb substrate; 20a, connector end; 21. a multi-array element ultrasonic transducer; 210. an ultrasonic transducer; 22. a flexible encapsulation layer; p, skin; x, blood vessel; y, user terminal.

Detailed Description

The present utility model will be described in detail with reference to the drawings and the detailed description, so that the above objects, features and advantages of the present utility model can be more clearly understood. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present utility model. The present utility model may be embodied in many other forms than described herein and similarly modified by those skilled in the art without departing from the spirit of the utility model, whereby the utility model is not limited to the specific embodiments disclosed below.

In the description of the present utility model, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings are merely for convenience in describing the present utility model and simplifying the description, and do not indicate or imply that the device or element being referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore should not be construed as limiting the present utility model.

Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In the description of the present utility model, the meaning of "plurality" means at least two, for example, two, three, etc., unless specifically defined otherwise.

In the present utility model, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly, through intermediaries, or both, may be in communication with each other or in interaction with each other, unless expressly defined otherwise. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.

In the utility model, unless expressly stated or limited otherwise, a first feature "up" or "down" a second feature may be the first and second features in direct contact, or the first and second features in indirect contact through an intervening medium. Moreover, a first feature being "above," "over" and "on" a second feature may be a first feature being directly above or obliquely above the second feature, or simply indicating that the first feature is level higher than the second feature. The first feature being "under", "below" and "beneath" the second feature may be the first feature being directly under or obliquely below the second feature, or simply indicating that the first feature is less level than the second feature.

It will be understood that when an element is referred to as being "fixed" or "disposed" on another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like are used herein for illustrative purposes only and are not meant to be the only embodiment.

As shown in fig. 1, the wearable ultrasonic doppler blood flow monitoring system according to the present embodiment includes a main body 1 and an ultrasonic sensor 2.

Referring to fig. 2, a host 1 is a conventional structure, and mainly includes a high voltage pulse excitation module 10, a gate circuit 11, a receiving unit 12, a control unit 13, and a display unit 14.

The high-voltage pulse excitation module 10 generates high-voltage pulses with the amplitude of 20-600V and the pulse width of less than 10us. The ultrasonic probe is driven to work by the high-voltage pulse excitation voltage generated in the way.

The gating circuit 11 mainly implements gating of the active ultrasound transducers, thereby reducing the complexity of the system, without having to equip each ultrasound transducer with separate excitation and reception circuits, wherein at least two of the number of channels gated by the gating circuit 11 can be operated simultaneously in order to ensure the detection requirements of continuous pulse doppler.

The receiving unit 12 mainly performs low-noise amplification, filtering, gain and sampling on the echo signal, and mainly consists of a low-noise amplifier LNA, a band-pass filter, an adjustable gain TGC and an analog-to-digital conversion chip ADC.

The control unit 13 mainly controls the operation of each part, including the control of the on-off state of each path of the gating switch, the time sequence of the exciting circuit, the gain of the TGC, the processing of the echo signal such as Fourier transform, etc., and is mainly composed of a single chip microcomputer for portable miniaturization.

The display unit 14 includes a display module 140, an information processing module 141, and an information transmission module 142, wherein the information transmission module 142 communicates with the user terminal Y through wires or/and wireless.

That is, the information transmission module can be a mobile battery module added with wireless transmission such as wifi, bluetooth and the like, and conveniently transmits the collected and processed data to the user terminal.

The user terminal Y is connected with the information transmission module in a wired and wireless mode, and the main functions of the user terminal Y include post-processing, displaying, alarming and the like of data. The user terminal can be a smart phone, a tablet computer, a mobile computer, a smart television and the like.

Referring to fig. 3, the ultrasonic sensor 2 includes a pcb substrate 20 having a long strip shape and being flexible, a plurality of groups of multi-array-element ultrasonic transducers 21 distributed on the pcb substrate 20 at intervals, and a flexible encapsulation layer 22 encapsulated on the surfaces of the groups of multi-array-element ultrasonic transducers 21 and capable of adhering to the skin.

The pcb substrate 20 is in communication with the gating circuit 11, and each group of multi-array element ultrasonic transducers 21 includes a plurality of ultrasonic transducers 210 spaced apart and forming unequal angles with the pcb substrate 20.

Each group of multi-array element ultrasonic transducers 21 at least comprises an ultrasonic transducer Ux with an angle of zero degree, and ultrasonic transducers Ua and ultrasonic transducers Ub which are positioned at two ends of the ultrasonic transducer Ux and distributed at intervals, wherein the ultrasonic transducer Ux can emit ultrasonic waves and receive ultrasonic waves, and one of the ultrasonic transducer Ua and the ultrasonic transducer Ub emits ultrasonic waves, and the other ultrasonic transducer Ub receives ultrasonic waves.

Specifically, each group of multi-array element ultrasonic transducers comprises ultrasonic transducers U1, U2, U3, U4 and U5 which are distributed in sequence, wherein U3 is an ultrasonic transducer Ux which is positioned in the middle and has an angle of zero degrees, two ultrasonic transducers Ua are respectively U1 and U2, and two ultrasonic transducers Ub are respectively U4 and U5. That is, each set of transducers consists of 5 transducers, 5 transducers being at a fixed angle, θ0, θ1,0, θ2, θ3, to the bottom pcb circuit.

Each group of ultrasonic transducers U1, U2, U3, U4 and U5 form the same angle with the pcb substrate.

The backing layer of each ultrasonic transducer 210 is an electrical conductor, a pad with an anode and a cathode is formed on the pcb substrate 20, the electrical conductor is connected to the pad through conductive adhesive or conductive wedge and is communicated with the cathode of the pad, the anode of the ultrasonic transducer 210 is communicated with the anode of the pad through a conductive line, and one end of the pcb substrate 20 forms a connector end 20a, and the connector end 20a is communicated with the gate circuit 11. Thus, the circuit conduction installation of the ultrasonic transducer is convenient.

The conductive adhesive is silver adhesive.

Each of the ultrasonic transducers 210 is connected to a flexible PCB circuit board at the bottom, and it is possible to control which specific transducers are operated by the gating module of the host.

The ultrasound transducer negative electrode (conductive backing) is directly adhered to the negative electrode pad of the pcb substrate by a conductive adhesive. In order to control the size and structure of the circuit, all the negative electrode bonding pads are conducted to form a common ground circuit, and then the positive electrode of the transducer is connected to the positive electrode bonding pad of the pcb substrate by means of bonding wires/gold wire welding and the like. All electrode pads at one end of the pcb substrate form a connector end and are connected to a host system through the connector end. In particular, to enhance the performance of flexible bending, the wires in the pcb substrate are curved or serpentine in shape.

The ultrasonic transducers 21 of multiple groups and multiple array elements are arranged in a linear array or an area array. That is, the whole flexible probe is formed by arranging a plurality of groups of transducers, and the transducers in the probe can be arranged in a linear array or an area array.

The ultrasonic transducer 210 may be a piezoelectric ultrasonic transducer, a piezoelectric composite ultrasonic probe, a capacitive ultrasonic probe or a film ultrasonic probe, and the working frequency range may be 1mhz to 15mhz, and the outer diameter size may be 0.1mm to 2 mm. That is, the ultrasonic transducers used may be piezoelectric ultrasonic transducers such as PZT/PMN-PT, piezoelectric composite ultrasonic probes such as 1-3 piezoelectric composites, capacitive ultrasonic probes such as CMUT, membrane type ultrasonic probes such as PVDF/AlN, or the like.

In this example, the plurality of sets of ultrasonic probes (ultrasonic transducers) constituting the flexible ultrasonic sensor 2, 5 transducers in each set of probes have the same operation center frequency, but the operation center frequencies of the transducers of different sets may be different. Depending on the need to monitor target depth, resolution and sensitivity.

The flexible encapsulation layer 22 is hydrogel, silicone, rubber, or tape. After the transducer is bonded to the pcb, the adhesive is integrally poured. The adhesive body mainly plays a role in protecting the transducer and pcb circuit and adhering to the skin of a human body.

The operation process of the blood flow monitoring system of the embodiment is as follows (taking a group of multi-array element ultrasonic transducers as an example):

When the ultrasonic sensor works, firstly, the multi-array element flexible ultrasonic sensor is tightly attached to the surface of human skin, the flexible probe is connected with a host, the host is started, and the normal connection of the probe and the normal communication with a terminal are confirmed according to the state of the host; secondly, the host machine sequentially and rapidly excites each transducer group through an internal gating switch and receives echo signals; finally, the ultrasonic transducer U3 works under the pulse Doppler mode, after excitation, receives echo signals by itself, after data reception, obtains central frequency by Fourier transformation, and works under the continuous Doppler mode in combination with the ultrasonic transducers U1, U2, U4 and U5, wherein the included angle of each ultrasonic transducer is theta ₀、θ₁、θ₂、θ₃, the ultrasonic transducers U1 and U2 emit ultrasonic waves, and the ultrasonic transducers U4 and U5 receive the ultrasonic waves, so that blood flow velocity is obtained.

Furthermore, according to this method, by monitoring the flow rates Vd and Vs of the blood vessels in the diastole and systole, the pulsatility index PI can also be obtained: pi= (Vs-Vd)/((Vs-Vd)/3+vd).

It is noted that in theory, only two angle values are needed for detection, but in order to obtain a more sensitive detection angle, each set is provided with 4 different transducer angles. The functions of the transducers U1, U2 and the transducers U4, U5 may also be reversed, becoming transducers U4, U5 transmitting ultrasound waves and transducers U1, U2 receiving ultrasound waves.

Further, since the flow velocity v of blood flow, the outer diameter d (diameter) of the blood vessel (obtained by the upper and lower vessel wall envelope signals of the echo signal) can be obtained, and the blood pressure can be expressed as:

P=ρv ²/2+C, where C is a constant, which can be obtained by calibration from blood pressure measured by a third party.

In summary, the present embodiment has the following advantages:

1. By utilizing the wearable multi-array flexible ultrasonic sensor and the Doppler technology, the real-time monitoring of Doppler information, the pulsation index, blood pressure and the like of human blood flow in a continuous Doppler mode and a pulse Doppler mode can be implemented, and an early warning value can be set at a terminal to give an alarm, so that medical staff, families and the like can be remotely reminded in emergency, and the defects of large volume, high professional technical requirements, complex operation and the like of the traditional ultrasonic Doppler equipment can be overcome;

2. the portable electronic device has the advantages of simple structure, low cost, portability, convenience and the like, and is expected to be applied to the clinical and personal monitoring fields;

3. Gating of the gating circuit eliminates the need for separate excitation and receiving circuits for each ultrasonic transducer, thereby reducing the complexity of the system;

4. The flexible encapsulation layer mainly serves to protect the transducer and pcb circuitry, as well as to adhere to the skin of the human body.

The present utility model has been described in detail with the purpose of enabling those skilled in the art to understand the contents of the present utility model and to implement the same, but not to limit the scope of the present utility model, and all equivalent changes or modifications made according to the spirit of the present utility model should be included in the scope of the present utility model.

Claims

1. The utility model provides a wearing formula supersound Doppler blood flow monitoring system, its characterized in that includes ultrasonic sensor, host computer: the ultrasonic sensor comprises a strip-shaped flexible pcb substrate, a plurality of groups of multi-array-element ultrasonic transducers distributed on the pcb substrate at intervals and a flexible packaging layer which is packaged on the surfaces of the plurality of groups of multi-array-element ultrasonic transducers and can be attached to the skin, wherein the pcb substrate is communicated with the host, each group of multi-array-element ultrasonic transducers comprises a plurality of ultrasonic transducers which are distributed at intervals and form different angles with the pcb substrate, each group of multi-array-element ultrasonic transducers at least comprises an ultrasonic transducer Ux with an angle of zero degree, ultrasonic transducers Ua and ultrasonic transducers Ub which are located at two ends of the ultrasonic transducer Ux and distributed at intervals, the ultrasonic transducers Ux can emit ultrasonic waves and receive ultrasonic waves, and one of the ultrasonic transducers Ua and the ultrasonic transducer Ub emits ultrasonic waves, and the other ultrasonic transducer Ub receives ultrasonic waves.

2. The wearable ultrasound doppler blood flow monitoring system of claim 1, wherein: each group of multi-array element ultrasonic transducers comprises ultrasonic transducers U1, U2, U3, U4 and U5 which are distributed in sequence, wherein U3 is an ultrasonic transducer Ux which is positioned in the middle and has an angle of zero degrees, two ultrasonic transducers Ua are respectively U1 and U2, and two ultrasonic transducers Ub are respectively U4 and U5.

3. The wearable ultrasound doppler blood flow monitoring system of claim 2, wherein: each group of ultrasonic transducers U1, U2, U3, U4 and U5 form the same angle with the pcb substrate.

4. The wearable ultrasound doppler blood flow monitoring system of claim 3, wherein: each backing layer of the ultrasonic transducer is a conductor, a bonding pad with an anode and a cathode is formed on the pcb substrate, the conductor is connected to the bonding pad through conductive adhesive or conductive wedge-shaped blocks and is communicated with the cathode of the bonding pad, the anode of the ultrasonic transducer is communicated with the anode of the bonding pad through a conductive circuit, one end of the pcb substrate forms a connector end, and the connector end is communicated with the host.

5. The wearable ultrasound doppler blood flow monitoring system of claim 4, wherein: the backing layer is a conductive material or an electrode plated with gold, silver or aluminum.

6. The wearable ultrasound doppler blood flow monitoring system of claim 1, wherein: and the plurality of groups of multi-array element ultrasonic transducers are arranged in a linear array or an area array.

7. The wearable ultrasound doppler blood flow monitoring system of claim 1, wherein: the ultrasonic transducer can be a piezoelectric ultrasonic transducer, a piezoelectric composite ultrasonic probe, a capacitive ultrasonic probe or a film type ultrasonic probe, and the working frequency range of the ultrasonic transducer can be 1 MHz-15 MHz, wherein the ultrasonic transducers of each group of multi-array element ultrasonic transducers have the same working center frequency; the outer diameter of the ultrasonic transducer is 0.1 mm-2 mm.

8. The wearable ultrasound doppler blood flow monitoring system of claim 1, wherein: the flexible packaging layer is hydrogel, silica gel, rubber or adhesive tape.

9. The wearable ultrasound doppler blood flow monitoring system of claim 1, wherein: the host comprises a high-voltage pulse excitation module, a gating circuit, a receiving unit, a control unit and a display unit, wherein the gating circuit is communicated with the pcb substrate, and the number of the paths gated by the gating circuit is at least two.

10. The wearable ultrasonic Doppler blood flow monitoring system of claim 9, wherein the display unit comprises a display module, an information processing module and an information transmission module, wherein the information transmission module is communicated with a user terminal through wires or/and wireless; the high-voltage pulse excitation module generates high-voltage pulse with the amplitude of 20-600V and the pulse width of less than 10us.