CN220879224U - Centrifugal mechanism for stem cell exosome processing - Google Patents
Centrifugal mechanism for stem cell exosome processing Download PDFInfo
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- CN220879224U CN220879224U CN202321914472.9U CN202321914472U CN220879224U CN 220879224 U CN220879224 U CN 220879224U CN 202321914472 U CN202321914472 U CN 202321914472U CN 220879224 U CN220879224 U CN 220879224U
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- fixing
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- centrifugal mechanism
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- 230000007246 mechanism Effects 0.000 title claims abstract description 46
- 210000000130 stem cell Anatomy 0.000 title claims abstract description 40
- 210000001808 exosome Anatomy 0.000 title claims abstract description 15
- 230000008093 supporting effect Effects 0.000 claims description 8
- 229920001821 foam rubber Polymers 0.000 claims description 3
- 230000002093 peripheral effect Effects 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 238000005381 potential energy Methods 0.000 abstract description 4
- 238000000034 method Methods 0.000 description 9
- 230000008569 process Effects 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 238000005119 centrifugation Methods 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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Abstract
The utility model relates to a centrifugal mechanism for stem cell exosome processing, which comprises a centrifugal machine, wherein the centrifugal machine is internally provided with the centrifugal mechanism, the centrifugal mechanism is provided with a fixing mechanism, the fixing mechanism comprises a plurality of circular grooves, the circular grooves are all arranged on the centrifugal mechanism, a fixing seat is fixed in the circular grooves, a placing groove is formed in the center of the top surface of the fixing seat, two fixing grooves are formed in the fixing seat, a telescopic rod is fixed in the fixing grooves, a spring is movably sleeved on the outer surface of the telescopic rod, a fixing block is fixed at one end of the telescopic rod, which is far away from the fixing groove, and a sponge cushion is fixed at one end of the fixing block, which is far away from the telescopic rod. Through setting up telescopic link and spring, utilize the elastic potential energy of spring can fix the stem cell test tube, utilize the scalability of telescopic link can realize fixing the stem cell test tube of different diameters to improve the practicality, reduce manufacturing cost to a certain extent.
Description
Technical Field
The utility model relates to the technical field of stem cell centrifugation, in particular to a centrifugal mechanism for stem cell exosome processing.
Background
Stem cells are a type of cells with infinite or immortalized self-renewal capacity and are capable of producing at least one type of highly differentiated daughter cells, and many methods are available for stem cell separation, and centrifugal separation is one of the common methods, and centrifugal technology is to utilize a strong centrifugal force generated when an object rotates at a high speed to make suspended particles placed in a rotating body settle or float, so that some particles achieve the purpose of concentration or separation from other particles.
For example, chinese patent (bulletin number: CN 212199206U) discloses a stem cell centrifuge, a slot is arranged in a centrifugal drum, a holding tube fixing sleeve is arranged through connection of the slot and a plug, and holding tubes with different types and different numbers can be selectively arranged, so that the holding tube fixing sleeve with different diameters and different numbers can be arranged, the use is more flexible, the applicability is stronger, and a container for centrifugation with other shapes can be placed by removing the holding tube fixing sleeve, so that the centrifugal cell centrifuge is very convenient and practical; the centrifugal rotary drum can be taken down, conveniently clear up the centrifugal rotary drum, but it still has following drawback in the in-service use:
According to the utility model, the aim of fixing stem cell test tubes with different diameters is achieved by replacing the fixing sleeves of the containing tubes with different types, so that the number of the required fixing sleeves of the containing tubes is large, and the manufacturing cost is relatively high.
Disclosure of utility model
Aiming at the defects of the prior art, the utility model provides a centrifugal mechanism for stem cell exosome processing, which has the advantages of being convenient for fixing stem cell test tubes with different diameters and the like, and solves the problem of higher manufacturing cost of the prior device.
In order to achieve the above purpose, the present utility model provides the following technical solutions: the centrifugal mechanism for stem cell exosome processing comprises a centrifugal machine, wherein the centrifugal machine is internally provided with the centrifugal mechanism, and the centrifugal mechanism is provided with a fixing mechanism;
in addition, fixed establishment includes a plurality of circular grooves, and is a plurality of the circular groove all sets up on the centrifugal mechanism, the circular inslot is fixed with the fixing base, the standing groove has been seted up to the center department of fixing base top surface, two fixed slots have been seted up to the inside of fixing base, the fixed inslot is fixed with the telescopic link, the surface activity cover of telescopic link is equipped with the spring, the telescopic link is kept away from the one end of fixed slot is fixed with the fixed block, the fixed block is kept away from the one end of telescopic link is fixed with the foam-rubber cushion.
Further, the two ends of the spring are respectively abutted between the fixing groove and the fixing block, and the fixing block is arc-shaped.
Further, the centrifugal mechanism comprises a centrifugal seat, the centrifugal seat is arranged in the centrifugal machine, a rotating rod is fixed at the center of the bottom surface of the centrifugal seat, a driven gear is fixed on the outer surface of the rotating rod, the centrifugal mechanism further comprises a driving motor fixedly installed on the right side of the inner top wall of the centrifugal machine, a driving gear is fixed on an output shaft of the driving motor, supporting blocks are fixed on the left side and the right side of the centrifugal seat, and the centrifugal mechanism further comprises an annular groove formed in the middle position of the inner peripheral wall of the centrifugal machine.
Further, the bottom end of the rotating rod is fixed with the center of the inner top wall of the centrifugal machine through a bearing, and the driving gear is meshed with the driven gear.
Further, the two supporting blocks are respectively inserted into the left side and the right side of the annular groove and are in rotary connection with the annular groove, and the top surface of the centrifugal seat and the top surface of the centrifugal machine are on the same horizontal line.
Further, the circular grooves are formed in the top surface of the centrifugal seat and are uniformly distributed in a circular arc shape.
Compared with the prior art, the technical scheme of the application has the following beneficial effects:
1. This stem cell exosome processing's centrifugal mechanism is equipped with fixed establishment, through setting up telescopic link and spring, utilizes the elastic potential energy of spring can fix the stem cell test tube, utilizes the scalability of telescopic link can realize fixing the stem cell test tube of different diameters to improve the practicality, reduce manufacturing cost to a certain extent.
2. The centrifugal mechanism for processing the stem cell exosome is provided with the centrifugal mechanism, can drive the driving gear to rotate through the driving motor, and can drive the driven gear to rotate through the driving gear, and further can drive the centrifugal seat to rotate at a high speed through the rotating rod, so that the purpose of centrifuging the stem cell is achieved.
Drawings
FIG. 1 is a schematic diagram of the structure of the present utility model;
FIG. 2 is a top view of the centrifuge of the present utility model;
fig. 3 is a schematic structural view of the fixing mechanism of the present utility model.
In the figure: 1 centrifugal machine, 2 centrifugal mechanism, 201 centrifugal seat, 202 dwang, 203 driven gear, 204 motor, 205 driving gear, 206 supporting block, 207 ring channel, 3 fixed mechanism, 301 circular channel, 302 fixing base, 303 fixed channel, 304 placing channel, 305 telescopic link, 306 spring, 307 fixed block, 308 foam-rubber cushion.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1, a centrifugal mechanism for stem cell exosome processing in this embodiment includes a centrifugal machine 1, a centrifugal mechanism 2 is disposed in the centrifugal machine 1, and a fixing mechanism 3 is disposed on the centrifugal mechanism 2.
Referring to fig. 2, in order to facilitate rapid fixation of stem cell test tubes with different diameters, the fixing mechanism 3 comprises a plurality of circular grooves 301, the circular grooves 301 are all arranged on the centrifugal mechanism 2, a fixing seat 302 is fixed in the circular grooves 301, a placing groove 304 is formed in the center of the top surface of the fixing seat 302, two fixing grooves 303 are formed in the fixing seat 302, a telescopic rod 305 is fixed in the fixing groove 303, the telescopic rod 305 comprises a fixing sleeve fixed in the fixing groove 303, the inner wall of the fixing sleeve is slidably connected with a sliding rod, the sliding rod slides on the inner wall of the sleeve, the setting of the telescopic rod 305 can achieve fixation of stem cell test tubes with different diameters, a spring 306 is movably sleeved on the outer surface of the telescopic rod 305, one end of the telescopic rod 305, far away from the fixing groove 303, is fixed with a fixing block 307, and one end of the fixing block 307, far away from the telescopic rod 305, is fixed with a sponge pad 308.
Wherein, the two ends of the spring 306 are respectively abutted between the fixing groove 303 and the fixing block 307, and the fixing block 307 is arc-shaped, and the test tube is cylindrical, so that the shape of the test tube is convenient to adapt.
Referring to fig. 3, in order to facilitate the centrifugal treatment of stem cells, the centrifugal mechanism 2 includes a centrifugal seat 201, the centrifugal seat 201 is disposed inside the centrifugal machine 1, a rotating rod 202 is fixed at the center of the bottom surface of the centrifugal seat 201, a driven gear 203 is fixed on the outer surface of the rotating rod 202, the centrifugal mechanism 2 further includes a driving motor 204 fixedly mounted on the right side of the inner top wall of the centrifugal machine 1, a driving gear 205 is fixed on an output shaft of the driving motor 204, supporting blocks 206 are fixed on the left and right sides of the centrifugal seat 201, and the centrifugal mechanism 2 further includes an annular groove 207 provided in the middle position of the inner peripheral wall of the centrifugal machine 1.
In addition, the bottom end of the rotating rod 202 is fixed with the center of the inner top wall of the centrifugal machine 1 through a bearing, so that the rotating rod 202 can rotate conveniently and simultaneously can support the centrifugal seat 201, and the driving gear 205 is meshed with the driven gear 203, so that the driven gear 203 can be driven to rotate conveniently through the driving motor 204.
Meanwhile, the two supporting blocks 206 are respectively inserted into the left and right sides of the inside of the annular groove 207 and are rotatably connected with the annular groove, and the top surface of the centrifugal seat 201 and the top surface of the centrifugal machine 1 are on the same horizontal line, so that the supporting effect on the centrifugal seat 201 can be improved.
Finally, the circular grooves 301 are all formed on the top surface of the centrifugal seat 201 and are uniformly distributed in a circular arc shape, so that a plurality of stem cell test tubes can be fixed at the same time, and the working efficiency can be improved.
The working principle of the embodiment is as follows: when the centrifugal stem cell centrifuge is used, stem cells to be centrifuged can be filled into the stem cell test tube, then the stem cell test tube is placed between the opposite sides of the two fixed blocks 307, the stem cell test tube extrudes the spring 306 in the process of placing the stem cell test tube, the spring 306 has elastic potential energy, the elastic potential energy of the spring 306 is utilized to reversely act on the stem cell test tube and fix the stem cell test tube, after the stem cell test tube is fixed, the driving gear 205 can be driven to rotate by the driving motor 204, the driven gear 203 is driven to rotate by the driving gear 205, and the centrifugal seat 201 is further driven to rotate at a high speed by the rotating rod 202, so that the aim of centrifuging the stem cells is achieved.
It is understood that the control mode of the present utility model is controlled by a controller, the control circuit of the controller is realized by simple programming by a person skilled in the art, the supply of power is also well known in the art, and the present utility model is mainly used to protect a mechanical device, so the present utility model does not explain the control mode and circuit connection in detail.
It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. A centrifugal mechanism for stem cell exosome processing, which comprises a centrifugal machine (1), and is characterized in that: a centrifugal mechanism (2) is arranged in the centrifugal machine (1), and a fixing mechanism (3) is arranged on the centrifugal mechanism (2);
In addition, fixed establishment (3) are including a plurality of circular grooves (301), and is a plurality of circular grooves (301) all set up on centrifugal mechanism (2), circular groove (301) internal fixation has fixing base (302), standing groove (304) have been seted up in the center department of fixing base (302) top surface, two fixed slots (303) have been seted up to the inside of fixing base (302), fixed slot (303) internal fixation has telescopic link (305), the surface movable sleeve of telescopic link (305) is equipped with spring (306), telescopic link (305) are kept away from one end of fixed slot (303) is fixed with fixed block (307), one end that fixed block (307) were kept away from telescopic link (305) is fixed with foam-rubber cushion (308).
2. A centrifugal mechanism for stem cell exosome processing according to claim 1, wherein: the two ends of the spring (306) are respectively abutted between the fixing groove (303) and the fixing block (307), and the fixing block (307) is arc-shaped.
3. A centrifugal mechanism for stem cell exosome processing according to claim 1, wherein: the centrifugal mechanism (2) comprises a centrifugal seat (201), the centrifugal seat (201) is arranged in the centrifugal machine (1), a rotating rod (202) is fixed at the center of the bottom surface of the centrifugal seat (201), a driven gear (203) is fixed on the outer surface of the rotating rod (202), the centrifugal mechanism (2) further comprises a driving motor (204) fixedly arranged on the right side of the inner top wall of the centrifugal machine (1), a driving gear (205) is fixed on an output shaft of the driving motor (204), supporting blocks (206) are fixed on the left side and the right side of the centrifugal seat (201), and the centrifugal mechanism (2) further comprises an annular groove (207) arranged in the middle position of the inner peripheral wall of the centrifugal machine (1).
4. A centrifugal mechanism for stem cell exosome processing according to claim 3, wherein: the bottom end of the rotating rod (202) is fixed with the center of the inner top wall of the centrifugal machine (1) through a bearing, and the driving gear (205) is meshed with the driven gear (203).
5. A centrifugal mechanism for stem cell exosome processing according to claim 3, wherein: the two supporting blocks (206) are respectively inserted into the left side and the right side of the inside of the annular groove (207) and are in rotary connection with the annular groove, and the top surface of the centrifugal seat (201) and the top surface of the centrifugal machine (1) are on the same horizontal line.
6. A centrifugal mechanism for stem cell exosome processing according to claim 3, wherein: the circular grooves (301) are formed in the top surface of the centrifugal seat (201) and are uniformly distributed in a circular arc shape.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321914472.9U CN220879224U (en) | 2023-07-20 | 2023-07-20 | Centrifugal mechanism for stem cell exosome processing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321914472.9U CN220879224U (en) | 2023-07-20 | 2023-07-20 | Centrifugal mechanism for stem cell exosome processing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220879224U true CN220879224U (en) | 2024-05-03 |
Family
ID=90867235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321914472.9U Active CN220879224U (en) | 2023-07-20 | 2023-07-20 | Centrifugal mechanism for stem cell exosome processing |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220879224U (en) |
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2023
- 2023-07-20 CN CN202321914472.9U patent/CN220879224U/en active Active
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