CN220012591U - Concentration detection box for separating target cell subset CD56 positive cells from peripheral blood - Google Patents
Concentration detection box for separating target cell subset CD56 positive cells from peripheral blood Download PDFInfo
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- CN220012591U CN220012591U CN202320949529.2U CN202320949529U CN220012591U CN 220012591 U CN220012591 U CN 220012591U CN 202320949529 U CN202320949529 U CN 202320949529U CN 220012591 U CN220012591 U CN 220012591U
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- movable
- supporting seat
- test tube
- frame
- peripheral blood
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- 238000001514 detection method Methods 0.000 title claims abstract description 20
- 210000005259 peripheral blood Anatomy 0.000 title claims abstract description 17
- 239000011886 peripheral blood Substances 0.000 title claims abstract description 17
- 101000581981 Homo sapiens Neural cell adhesion molecule 1 Proteins 0.000 title claims abstract description 16
- 102100027347 Neural cell adhesion molecule 1 Human genes 0.000 title claims abstract description 16
- 230000007246 mechanism Effects 0.000 claims abstract description 30
- 238000000926 separation method Methods 0.000 claims abstract description 10
- 238000007789 sealing Methods 0.000 claims description 3
- 238000009434 installation Methods 0.000 claims 1
- 210000004027 cell Anatomy 0.000 description 26
- 230000009471 action Effects 0.000 description 6
- 238000000034 method Methods 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 210000001185 bone marrow Anatomy 0.000 description 2
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 210000000130 stem cell Anatomy 0.000 description 2
- 238000005054 agglomeration Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model relates to the technical field of cell detection, and discloses a concentration detection box for CD56 positive cells of a target cell subset for peripheral blood separation, which comprises a mounting frame, wherein a movable mechanism is mounted in the middle of the inner bottom wall of the mounting frame, a control panel is mounted at the top of the left side of the mounting frame, a connecting rod is mounted in the movable mechanism, a worm wheel is mounted at the top end of the connecting rod, a supporting seat is mounted at the top end of the worm wheel, a driving mechanism is mounted at the left side of the inner bottom wall of the mounting frame, the left side of the worm wheel is meshed with the driving mechanism, and a test tube is mounted in the supporting seat. According to the test tube fixing device, the test tube can be supported through the supporting seat, the reset spring can push the movable rod, the fixed blocks can be pushed out from the inside of the movable groove, the two fixed blocks penetrate into the supporting seat, the two fixed blocks can clamp and fix the test tube in the supporting seat, and the test tube is kept stable in the mounting frame.
Description
Technical Field
The utility model relates to the technical field of cell detection, in particular to a concentration detection box for separating target cell subset CD56 positive cells from peripheral blood.
Background
The peripheral blood is blood except bone marrow, and some methods are commonly used clinically to release hematopoietic stem cells in bone marrow into blood, and then extract and separate the hematopoietic stem cells from the blood, so that the obtained stem cells are called peripheral blood stem cells, and a new concept of peripheral blood is first proposed in the life ark project of human beginning in the twenty-first century.
The existing concentration detection box for CD56 positive cells cannot disperse cells in a test tube to cause cell agglomeration so as to influence the detection of the cell concentration, cannot keep stable when the test tube rotates, and aims to solve the problems by providing the concentration detection box for CD56 positive cells of a target cell subset for peripheral blood separation.
Disclosure of Invention
The utility model aims to solve the defects existing in the prior art, such as: the existing concentration detection box for CD56 positive cells cannot disperse cells in a test tube when in use, so that cells are clustered to influence the detection of the cell concentration, the test tube cannot be kept stable when rotating, the test tube cannot be fixed when rotating at a high speed, and the concentration detection box for CD56 positive cells, which is a target cell subset for separating peripheral blood, is provided.
In order to achieve the above purpose, the present utility model adopts the following technical scheme:
the utility model provides a concentration detection box for CD56 positive cells of peripheral blood separation purpose cell subgroup, includes the mounting bracket, the mid-mounting of diapire has movable mechanism in the mounting bracket, control panel is installed at the left top of mounting bracket, movable mechanism's internally mounted has the connecting rod, the worm wheel is installed on the top of connecting rod, the supporting seat is installed on the top of worm wheel, actuating mechanism is installed on the left side of diapire in the mounting bracket, the left side and the actuating mechanism of worm wheel mesh mutually, the internally mounted of supporting seat has the test tube, fixed establishment is all installed at the top of supporting seat both sides, one side of fixed establishment contacts with the test tube respectively, electric putter is all installed at the top of two inner walls about the mounting bracket, supporting sleeve is all installed to one side that electric putter kept away from the mounting bracket, the top at the test tube is overlapped respectively to the supporting sleeve, the closure apron is installed on the top of mounting bracket, the solid fixed ring is installed to the bottom of closure apron, gu fixed ring screw thread installs at the top of mounting bracket inner chamber.
Preferably, the fixing mechanism comprises a fixing frame for installing the tops of two sides of the supporting seat, the inner walls of the fixing frame are provided with reset springs, one ends of the reset springs are provided with movable rods, the tops of the left and right inner walls of the supporting seat are provided with movable grooves, the inside of each movable groove is provided with a fixing block, and one ends of the movable rods are respectively connected with the fixing blocks.
Preferably, the driving mechanism comprises a driving frame arranged on the left side of the inner bottom wall of the mounting frame, a worm is movably arranged in the driving frame, a driving motor is arranged on the front face of the driving frame, an output shaft of the driving motor penetrates through the driving frame to be connected with the worm, the driving motor is electrically connected with the control panel, and the left side of the worm wheel is meshed with the worm.
Preferably, the movable mechanism comprises a movable frame arranged in the middle of the inner bottom wall of the mounting frame, a movable bearing is arranged in the movable frame, and the bottom end of the connecting rod is connected with the movable bearing.
Preferably, a supporting groove is formed in the middle of the inner side of the supporting sleeve, and supporting pulleys which are uniformly distributed are movably arranged in the supporting groove.
Preferably, an anti-slip washer is mounted at the bottom end of the mounting frame.
Compared with the prior art, the utility model has the beneficial effects that:
(1) According to the test tube fixing device, the test tube can be supported through the supporting seat, the reset spring can push the movable rod, the fixed blocks can be pushed out from the inside of the movable groove, the two fixed blocks penetrate into the supporting seat, the two fixed blocks can clamp and fix the test tube in the supporting seat, the test tube can be kept stable in the mounting frame, the movable frame and the movable bearing can play a role in stably supporting the supporting seat, the friction degree between the supporting seat and the mounting frame is reduced when the supporting seat rotates, and the supporting seat can stably rotate.
(2) According to the utility model, the drive motor is controlled to rotate through the control panel, so that the drive motor drives the worm to rotate, the worm and the worm wheel are meshed for transmission, the support seat can be driven to rotate stably at a high speed, the test tube can be driven to rotate, cell clusters in the test tube can be dispersed through the action of centrifugal force, the cell concentration can be conveniently detected, and the electric push rod is controlled to extend through the control panel, so that the two support sleeves can be simultaneously driven to be sleeved at the top of the test tube, the support pulley can be contacted with the outer side of the test tube, the test tube can be kept stable during rotation, the friction between the test tube and the support sleeve can be reduced, and the test tube is prevented from toppling during rotation.
Drawings
FIG. 1 is a schematic view of the overall internal structure of the present utility model;
FIG. 2 is a schematic view of the internal structure of the support sleeve of the present utility model;
FIG. 3 is a schematic diagram of a first embodiment of the present utility model;
FIG. 4 is a schematic structural diagram of a second embodiment of the present utility model;
fig. 5 is a schematic structural diagram of a third embodiment of the present utility model.
In the figure: 1. a mounting frame; 2. a control panel; 3. an electric push rod; 4. closing the cover plate; 5. a fixing ring; 6. a support base; 7. a fixing mechanism; 71. a fixing frame; 72. a return spring; 73. a movable rod; 74. a movable groove; 75. a fixed block; 8. a driving mechanism; 81. a drive rack; 82. a worm; 83. a driving motor; 9. a movable mechanism; 91. a movable frame; 92. a movable bearing; 10. an anti-slip washer; 11. a worm wheel; 12. a test tube; 13. a support sleeve; 14. a connecting rod; 15. a support groove; 16. and supporting the pulley.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments.
In the description of the present utility model, it should be understood that the terms "upper," "lower," "front," "rear," "left," "right," "top," "bottom," "inner," "outer," and the like indicate or are based on the orientation or positional relationship shown in the drawings, merely to facilitate description of the present utility model and to simplify the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present utility model.
Referring to FIGS. 1-5, a concentration detection box for CD56 positive cells of a target cell subset for peripheral blood separation comprises a mounting frame 1, wherein a movable mechanism 9 is arranged in the middle of the inner bottom wall of the mounting frame 1, a control panel 2 is arranged at the top of the left side of the mounting frame 1, a connecting rod 14 is arranged in the movable mechanism 9, a worm wheel 11 is arranged at the top end of the connecting rod 14, a supporting seat 6 is arranged at the top end of the worm wheel 11, a driving mechanism 8 is arranged at the left side of the inner bottom wall of the mounting frame 1, the left side of the worm wheel 11 is meshed with the driving mechanism 8, a test tube 12 is arranged in the supporting seat 6, fixing mechanisms 7 are arranged at the tops of the two sides of the supporting seat 6, one side of each fixing mechanism 7 is respectively contacted with the test tube 12, electric push rods 3 are arranged at the tops of the left and right inner walls of the mounting frame 1, supporting sleeves 13 are arranged at the sides of the electric push rods 3 far from the mounting frame 1, the electric push rods 3 are controlled to extend through the control panel 2, can drive two support sleeves 13 to be sleeved at the top of a test tube 12 simultaneously, so that a support pulley 16 can be contacted with the outer side of the test tube 12, the test tube 12 keeps stable during rotation, the support sleeves 13 are respectively sleeved at the top of the test tube 12, a support groove 15 is formed in the middle of the inner side of each support sleeve 13, the support pulleys 16 which are uniformly distributed are movably arranged in the support grooves 15, the support pulleys 16 can be contacted with the outer side of the test tube 12, the test tube 12 keeps stable during rotation, friction between the test tube 12 and the support sleeves 13 can be reduced, a sealing cover plate 4 is arranged at the top end of the mounting frame 1, a fixing ring 5 is arranged at the bottom end of the sealing cover plate 4, threads of the fixing ring 5 are arranged at the top of the inner cavity of the mounting frame 1, an anti-slip gasket 10 is arranged at the bottom end of the mounting frame 1, the mounting frame 1 can be stably placed on a support surface through the anti-slip gasket 10, preventing slippage of the entire device.
Embodiment one:
as shown in fig. 3, the fixing mechanism 7 includes a fixing frame 71 for mounting the tops of two sides of the supporting seat 6, the inner wall of the fixing frame 71 is provided with a return spring 72, one end of the return spring 72 is provided with a movable rod 73, the tops of the left and right inner walls of the supporting seat 6 are provided with movable grooves 74, the inside of the movable grooves 74 is provided with fixed blocks 75 movably, one end of the movable rod 73 is respectively connected with the fixed blocks 75, the test tube 12 can be supported by the supporting seat 6, the return spring 72 can push the movable rods 73, the fixed blocks 75 can be pushed out from the inside of the movable grooves 74, the two fixed blocks 75 penetrate into the inside of the supporting seat 6, the two fixed blocks 75 can clamp and fix the test tube 12 in the supporting seat 6, and the test tube 12 is kept stable in the inside of the mounting frame 1.
Embodiment two:
as shown in fig. 4, the driving mechanism 8 includes a driving frame 81 mounted on the left side of the bottom wall in the mounting frame 1, a worm 82 is movably mounted in the driving frame 81, a driving motor 83 is mounted on the front surface of the driving frame 81, an output shaft of the driving motor 83 penetrates through the driving frame 81 and is connected with the worm 82, the driving motor 83 is electrically connected with the control panel 2, the left side of the worm wheel 11 is meshed with the worm 82, the driving motor 83 is controlled to rotate by the control panel 2, the driving motor 83 drives the worm 82 to rotate, the worm 82 is meshed with the worm wheel 11 for transmission, the supporting seat 6 can be driven to rotate stably at a high speed, the test tube 12 can be driven to rotate, and cell groups in the test tube 12 can be dispersed by the action of centrifugal force and can be conveniently detected.
Embodiment III:
as shown in fig. 5, the movable mechanism 9 includes a movable frame 91 installed in the middle of the inner bottom wall of the mounting frame 1, a movable bearing 92 is installed in the movable frame 91, the bottom end of the connecting rod 14 is connected with the movable bearing 92, and the movable frame 91 and the movable bearing 92 can play a role in stably supporting the supporting seat 6, so that the friction degree between the supporting seat 6 and the mounting frame 1 is reduced when the supporting seat 6 rotates, and the supporting seat 6 can stably rotate.
In the utility model, when a user uses the device, a test tube 12 for storing cell clusters is placed in the support seat 6, the reset spring 72 can push the movable rod 73, the fixed blocks 75 can be pushed out from the inside of the movable groove 74, the two fixed blocks 75 are enabled to penetrate into the support seat 6, the two fixed blocks 75 can clamp and fix the test tube 12 in the support seat 6, the control panel 2 controls the electric push rod 3 to extend, the two support sleeves 13 can be driven to be sleeved at the top of the test tube 12 at the same time, the support pulley 16 can be contacted with the outer side of the test tube 12, the control panel 2 controls the driving motor 83 to rotate, the driving motor 83 drives the worm 82 to rotate, the worm 82 is meshed with the worm wheel 11 to drive the support seat 6 to rotate stably at a high speed, and the cell clusters in the test tube 12 can be dispersed by the action of centrifugal force.
The foregoing is only a preferred embodiment of the present utility model, but the scope of the present utility model is not limited thereto, and any person skilled in the art, who is within the scope of the present utility model, should make equivalent substitutions or modifications according to the technical scheme of the present utility model and the inventive concept thereof, and should be covered by the scope of the present utility model.
It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Claims (6)
1. The utility model provides a concentration detection box for CD56 positive cells of peripheral blood separation purpose cell subgroup, includes mounting bracket (1), its characterized in that, mid-mounting of diapire has movable mechanism (9) in mounting bracket (1), control panel (2) are installed at the top of mounting bracket (1) left side, the internally mounted of movable mechanism (9) has connecting rod (14), worm wheel (11) are installed on the top of connecting rod (14), supporting seat (6) are installed on the top of worm wheel (11), actuating mechanism (8) are installed in the left side of diapire in mounting bracket (1), the left side and actuating mechanism (8) of worm wheel (11) mesh mutually, internally mounted of supporting seat (6) has test tube (12), fixed establishment (7) are all installed at the top of supporting seat (6) both sides, one side of fixed establishment (7) contacts with test tube (12) respectively, electric putter (3) are all installed at the top of two inner walls about mounting bracket (1), supporting sleeve (13) are all installed to one side that electric putter (3) kept away from (1), supporting sleeve (13) are installed at the top of mounting bracket (1) respectively, top (4) are installed at the top of sealing cover (4), the fixing ring (5) is arranged at the top of the inner cavity of the mounting frame (1) in a threaded manner.
2. The concentration detection box for CD56 positive cells of the cell subset for peripheral blood separation purpose according to claim 1, characterized in that the fixing mechanism (7) comprises fixing frames (71) arranged at the tops of two sides of the supporting seat (6), return springs (72) are arranged on the inner walls of the fixing frames (71), movable rods (73) are arranged at one ends of the return springs (72), movable grooves (74) are formed in the tops of the left inner wall and the right inner wall of the supporting seat (6), fixing blocks (75) are movably arranged in the movable grooves (74), and one ends of the movable rods (73) are connected with the fixing blocks (75) respectively.
3. The concentration detection box for CD56 positive cells of a cell subset for peripheral blood separation according to claim 1, wherein the driving mechanism (8) comprises a driving frame (81) arranged on the left side of the inner bottom wall of the mounting frame (1), a worm (82) is movably arranged in the driving frame (81), a driving motor (83) is arranged on the front surface of the driving frame (81), an output shaft of the driving motor (83) penetrates through the driving frame (81) to be connected with the worm (82), the driving motor (83) is electrically connected with the control panel (2), and the left side of the worm wheel (11) is meshed with the worm (82).
4. The concentration detection box for CD56 positive cells of the cell subset of the peripheral blood separation purpose according to claim 1, wherein the movable mechanism (9) comprises a movable frame (91) arranged in the middle of the inner bottom wall of the installation frame (1), a movable bearing (92) is arranged in the movable frame (91), and the bottom end of the connecting rod (14) is connected with the movable bearing (92).
5. The concentration detection box for CD56 positive cells of the cell subset for peripheral blood separation purpose according to claim 1, wherein the middle part of the inner side of the supporting sleeve (13) is provided with a supporting groove (15), and the inside of the supporting groove (15) is movably provided with supporting pulleys (16) which are uniformly distributed.
6. The concentration detection box for CD56 positive cells of a cell subset of a peripheral blood separation target according to claim 1, wherein the bottom end of the mounting frame (1) is provided with an anti-slip gasket (10).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320949529.2U CN220012591U (en) | 2023-04-24 | 2023-04-24 | Concentration detection box for separating target cell subset CD56 positive cells from peripheral blood |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320949529.2U CN220012591U (en) | 2023-04-24 | 2023-04-24 | Concentration detection box for separating target cell subset CD56 positive cells from peripheral blood |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220012591U true CN220012591U (en) | 2023-11-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320949529.2U Active CN220012591U (en) | 2023-04-24 | 2023-04-24 | Concentration detection box for separating target cell subset CD56 positive cells from peripheral blood |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220012591U (en) |
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2023
- 2023-04-24 CN CN202320949529.2U patent/CN220012591U/en active Active
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