CN220831313U - Experimental animal negative pressure isolator with multiple ventilation modes - Google Patents

Abstract

The utility model discloses a multi-ventilation-mode experimental animal negative pressure isolator, which belongs to the technical field of biological safety protection equipment and comprises a host machine and combined cabin bodies positioned at two sides of the host machine; the combined cabin body is composed of a plurality of independent cabins, each cabin is provided with a sealing door, an air inlet filter and an air exhaust filter are arranged in the main machine, and the tree shrew ferrets are isolated under negative pressure through the plurality of cabins which are mutually communicated and independent, so that the accuracy and the independence of the test can be ensured. The isolator and the host are of split independent structures, the isolators are arranged on two sides of the host, the structure is compact, the disassembly is convenient, the transportation is convenient, and the environmental adaptability of the device is improved. The cabin exhaust of one cabin is communicated with cabin air inlets of other cabins through the communicating pipe provided with the valve, so that the independent ventilation mode can be realized, cross infection can be avoided, and the qualitative analysis on virus infection can be conveniently carried out through the communicating pipe in the virus attack mode.

Description

Experimental animal negative pressure isolator with multiple ventilation modes

Technical Field

The utility model relates to the technical field of biological safety protection equipment, in particular to a multi-ventilation-mode experimental animal negative pressure isolator.

Background

The biosafety type isolator is an important device for protecting the health of experimental animals. The method provides a sterile environment, effectively isolates the contact between the experimental animal and the external environment, reduces the risk of cross infection, and ensures the accuracy and reliability of experimental results. The biosafety isolator employs efficient air filtration systems and aseptic techniques to effectively prevent the ingress of microorganisms and pathogens. It is typically comprised of one or more closed compartments and a negative pressure ventilation system to ensure that the laboratory animal is subjected to the experiment in a clean, sterile environment.

Application number: the utility model patent of CN201320794121.9 discloses a negative pressure isolator for raising experimental animals, the ventilation system comprises an exhaust primary filter, a primary exhaust efficient filter, a secondary exhaust efficient filter, a fan and a high-efficient filter which are sequentially connected, the high-efficient filter is connected with a fresh air port for supplying air to the isolator, the isolator improves the overall tightness, simplifies the operation procedure of article transfer, realizes the on-line monitoring of the integrity of the filter and the on-line replacement function of the filter, and avoids the pollution to the external environment when the filter is replaced.

However, the isolation bin of the negative pressure isolator cannot meet the requirement of isolating a plurality of individuals independently, and the ventilation mode is single and cannot be changed according to actual requirements.

Disclosure of utility model

The utility model aims at: in order to solve the problems that the isolation bin of the traditional animal feeding negative-pressure isolator cannot meet the independent isolation requirement of a plurality of individuals and the ventilation mode is single and can not be changed according to actual requirements, the experimental animal negative-pressure isolator with multiple ventilation modes is provided.

In order to achieve the above purpose, the technical scheme of the utility model is as follows: a multi-ventilation-mode experimental animal negative pressure isolator comprises a main machine and combined cabin bodies positioned at two sides of the main machine; the combined cabin body is composed of a plurality of independent cabins, each cabin is provided with a sealing door respectively, an air inlet filter and an air exhaust filter are arranged in the host, each cabin of the combined cabin body is respectively communicated with the air inlet filter and the air exhaust filter, the cabin air exhaust of one cabin is communicated with cabin air inlets of other cabins through a communicating pipe provided with a valve, the air inlets of the air inlet filters are respectively connected with a total air inlet pipe and a disinfection air inlet pipe, and the air outlets of the air exhaust filters are respectively connected with a total air exhaust pipe and a disinfection calandria.

Preferably, the upper part of the front side of each cabin of the combined cabin body is provided with a cabin air inlet communicated with an air inlet filter, and the lower part of the rear side of each cabin is provided with a cabin air outlet communicated with an air exhaust filter. The air curtain can be isolated in front of the cabin, and laminar air supply and exhaust is formed, so that the clean air environment in the cabin can be ensured all the time.

Preferably, an electric box is further arranged in the host, a differential pressure meter and an operation screen are further arranged on the electric box, and the differential pressure meter and the operation screen are located on the front side of the host.

Preferably, the combined cabin body comprises a cabin, a cabin II, a cabin III and a cabin IV, the outlet end of the air inlet filter is connected with the cabin I, the cabin II, the cabin III and the cabin IV through a cabin air supply pipe, a cabin II air supply pipe, a cabin III air supply pipe and a cabin IV air supply pipe respectively, and the air inlet end of the air exhaust filter is connected with the cabin I, the cabin II, the cabin III and the cabin IV through a cabin exhaust pipe, a cabin II exhaust pipe, a cabin III exhaust pipe and a cabin IV exhaust pipe respectively.

Preferably, the first cabin blast pipe, the second cabin blast pipe, the third cabin blast pipe and the fourth cabin blast pipe, the first cabin exhaust pipe, the second cabin exhaust pipe, the third cabin exhaust pipe, the fourth cabin exhaust pipe, the total air inlet pipe and the total exhaust pipe are respectively provided with an independent electric disc valve, and the disinfection inlet pipe and the disinfection calandria are respectively provided with an independent electric disc valve.

Preferably, the connecting pipes comprise a second cabin connecting pipe, a third cabin connecting pipe and a fourth cabin connecting pipe, a first cabin exhaust pipe is connected with the second cabin air supply pipe through the second cabin connecting pipe, a first cabin exhaust pipe is connected with the third cabin air supply pipe through the third cabin connecting pipe, a first cabin exhaust pipe is connected with the fourth cabin air supply pipe through the fourth cabin connecting pipe, and valves are arranged on the second cabin connecting pipe, the third cabin connecting pipe and the fourth cabin connecting pipe.

Preferably, the bottom of each cabin is provided with a manure tray in a sliding manner, the lower part of the sealing door is provided with a butt joint opening corresponding to the manure tray, a manure tray door plate is arranged at the butt joint opening, and two sides of the manure tray are also provided with urethral catheterization plates.

Preferably, the catheterization board comprises an upper guide plate and a lower fixing plate, wherein the upper guide plate is gradually and downwards inclined along the direction close to the manure tray, the lower fixing plate is fixed on the lower side of the upper guide plate, the upper end of the lower fixing plate is connected with the side edge of the upper guide plate through a transverse connecting plate, and the two sides of the manure tray are arranged on the lower side of the connecting plate.

Preferably, the middle parts of two sides of the inner wall of each cabin are provided with a cage framework sliding rail.

Preferably, the docking port is also fixed with a manure tray docking seat, a through groove corresponding to the manure tray is arranged on the manure tray docking seat, the manure tray door plate covers the outer side of the manure tray docking seat, and an annular groove is arranged on the manure tray docking seat.

Preferably, the joint of the bulkheads of each cabin is in a circular arc structure.

Preferably, a small door is arranged in the middle of the sealing door, the sealing door is mounted on the combined cabin body through a cabin door sealing lock, and a handle is further arranged on the side face of the sealing door.

Preferably, the main machine is also provided with an air inlet, and universal wheels are arranged at the bottoms of the main machine and the combined cabin body.

Compared with the prior art, the experimental animal negative pressure isolator with multiple ventilation modes is provided by improving the experimental animal negative pressure isolator, and has the following improvement and advantages:

1. According to the utility model, the tree shrew ferret is isolated under negative pressure through the plurality of mutually communicated and independent cabins, so that the accuracy and independence of the test can be ensured. The isolator and the host are of split independent structures, the isolators are arranged on two sides of the host, the structure is compact, the disassembly is convenient, the transportation is convenient, and the environmental adaptability of the device is improved.

2. The cabin exhaust of one cabin is communicated with cabin air inlets of other cabins through the communicating pipe provided with the valve, so that the independent ventilation mode can be realized, cross infection can be avoided, and the qualitative analysis on virus infection can be conveniently carried out through the communicating pipe in the virus attack mode.

3. According to the utility model, through the mutual matching of the air inlet pipes, the air outlet pipes and the electric butterfly valves, the adjustment and isolation of various modes can be realized, and the design can ensure that the tree shrew ferret negative pressure isolator can change the ventilation mode according to actual requirements, so that the practicality and the working efficiency of the device are greatly improved.

4. The joint between the bulkheads of each cabin adopts the arc design, so that the staff can clean residues after experiments. And the middle part is designed with a cage frame sliding rail, which is convenient for taking and placing the cage. The bottom is provided with the catheterization board, reduces the whole size of excrement dish, makes things convenient for personnel's operation, realizes accurate catheterization, does not reveal excrement and urine.

Drawings

Fig. 1 is a front view of the structure of the present utility model.

FIG. 2 is a schematic diagram of a pipeline structure at the rear of a host in the present utility model.

FIG. 3 is a schematic diagram of a host according to the present utility model.

Fig. 4 is a side view of a host in the present utility model.

Fig. 5 is a schematic structural view of the combined cabin in the present utility model.

Fig. 6 is a schematic view of the structure of the sealing door in the present utility model.

Fig. 7 is a schematic view of the cabin interior structure of the combined cabin in the present utility model.

Fig. 8 is a partial enlarged view at a in fig. 7.

In the figure: 1. host 101, differential pressure gauge 102, operation screen 103, air inlet 104, universal wheel 105, air inlet filter 106, air outlet filter 107, total air inlet duct 108, total air outlet duct 109, electric box 1101, cabin air inlet duct 1102, cabin air outlet duct 1103, cabin air outlet duct 1104, cabin air outlet duct 1111, cabin air outlet duct 1112, cabin air outlet duct 1113, cabin air outlet duct 1114, cabin air outlet duct 112, electric dish valve 113, disinfection inlet duct 114, disinfection drain 115, cabin connecting tube 116, cabin connecting tube 117, cabin connecting tube 2, combined cabin 201, cabin 202, cabin 203, cabin 204, cabin 205, cage frame rail 206, urinary board 2601, upper guide board 2602, lower fixing board 2603, connecting board 207, manure tray 208, sealing door 209, manure tray docking seat 210, manure tray door 211, small door 212, sealing lock 213, handle 214, and groove.

Detailed Description

The utility model is further described with reference to fig. 1-8.

As shown in fig. 1-4, the experimental animal negative pressure isolator with multiple ventilation modes comprises a main machine 1 and combined cabins 2 positioned at two sides of the main machine 1; the combined cabin body 2 is composed of a plurality of independent cabins, an air inlet filter 105 and an air outlet filter 106 are arranged in the main machine 1, an air inlet of the air inlet filter 105 is connected with a main air inlet pipe 107 and a disinfection inlet pipe 113, an air outlet of the air outlet filter 106 is connected with a main air outlet pipe 108 and a disinfection calandria 114, and the disinfection inlet pipe 113 is connected with external disinfection equipment.

The inside of the host 1 is also provided with an electric box 109, and the electric box 109 is also provided with a differential pressure gauge 101 and an operation screen 102, the differential pressure gauge 101 and the operation screen 102 being located on the front side of the host 1. The main machine 1 is also provided with an air inlet 103, and universal wheels 104 are arranged at the bottoms of the main machine 1 and the combined cabin 2.

In order to isolate the individual compartments independently, the combined compartment 2 is divided into a plurality of independent compartments and symmetrically disposed on both sides of the main unit 1. The air intake filter 105 is used for filtering and purifying the gas entering the cabin, preventing other factors from interfering with the test result, and the air exhaust filter 106 is used for filtering the circulated gas, preventing the harmful gas from polluting the environment. The host 1 is also provided with a differential pressure gauge 101 and an operation screen 102, which can be convenient for an operator to observe and further operate, and an electrical box 109 is used for controlling the operation and data processing of the whole device.

Specifically, the combined cabin body 2 includes four cabins of a cabin 201, a cabin 202, a cabin 203 and a cabin 204, the outlet end of the air intake filter 105 is connected with the four cabins of the cabin 201, the cabin 202, the cabin 203 and the cabin 204 through a cabin air supply pipe 1101, a cabin air supply pipe 1102, a cabin air supply pipe 1103 and a cabin air supply pipe 1104, and the air intake end of the air intake filter 106 is connected with the four cabins of the cabin 201, the cabin 202, the cabin 203 and the cabin 204 through a cabin air exhaust pipe 1111, a cabin air exhaust pipe 1112, a cabin air exhaust pipe 1113 and a cabin air exhaust pipe 1114.

The upper part of the front side of each cabin is provided with a cabin air inlet communicated with an air inlet filter 105, the lower part of the rear side of each cabin is provided with a cabin air outlet communicated with an air exhaust filter 106, an isolated air curtain can be formed in front of the cabin, and laminar air supply and exhaust can be formed.

In order to meet the ventilation modes of different cabins, the outlet end of the air inlet filter 105 is respectively connected with a cabin air supply pipe 1101, a cabin air supply pipe 1102, a cabin air supply pipe 1103 and a cabin air supply pipe 1104, and the air inlet end of the air exhaust filter 106 is respectively connected with a cabin air exhaust pipe 1111, a cabin air exhaust pipe 1112, a cabin air exhaust pipe 1113 and a cabin air exhaust pipe 1114, which can ensure that independent air supply pipes and air exhaust pipes are arranged in each cabin.

The main air inlet pipe 107, the main exhaust pipe 108, the cabin air supply pipe 1101, the cabin air supply pipe 1102 No. two, the cabin air supply pipe 1103 and the cabin air supply pipe 1104 No. four, the cabin exhaust pipe 1111, the cabin exhaust pipe 1112, the cabin exhaust pipe 1113 and the cabin exhaust pipe 1114 are respectively provided with an independent electric disc valve 112, the disinfection air inlet pipe 113 and the disinfection calandria 114 are also provided with independent electric disc valves 112, and the ventilation mode of each cabin can be adjusted.

The first cabin exhaust pipe 1111 is connected with the second cabin air supply pipe 1102 through the second cabin connecting pipe 115, the first cabin exhaust pipe 1111 is connected with the third cabin air supply pipe 1103 through the third cabin connecting pipe 116, the first cabin exhaust pipe 1111 is connected with the fourth cabin air supply pipe 1104 through the fourth cabin connecting pipe 117, in order to realize the virus infection mode, and further the second cabin 202, the third cabin 203 and the fourth cabin 204 are infected through the first cabin 201, so that the first cabin exhaust pipe 1111 and the second cabin air supply pipe 1102 are connected through the second cabin connecting pipe 115, the first cabin exhaust pipe 1111 and the third cabin air supply pipe 1103 are connected through the third cabin connecting pipe 116, the first cabin exhaust pipe 1111 and the fourth cabin air supply pipe 1104 are connected through the fourth cabin connecting pipe 117, the foundation is laid for the infection mode, and the pharmacological test of some viruses is facilitated.

Referring to fig. 5-6, two sides of the inner walls of the first cabin 201, the second cabin 202, the third cabin 203 and the fourth cabin 204 are provided with cage frame sliding rails 205, and the cage frame sliding rails 205 can enable the cage to be suspended in the cabin, prevent dirt such as fecaluria from accumulating at the bottom of the cabin, and reduce cleaning difficulty.

The bottom of each cabin is provided with the catheterization board 206 and the excrement dish 207, and the cabin bottom is equipped with continuation formula catheterization board 206, reduces excrement dish 207 overall dimension, makes things convenient for personnel to operate, realizes accurate catheterization, does not reveal excrement urine.

Each cabin is installed and sealed through a sealing door 208, a small door 211 is arranged in the middle of the sealing door 208, the sealing door 208 is installed on the combined cabin body 2 through a cabin door sealing lock 212, and a handle 213 is further arranged on the side face of the sealing door 208. The small door 211 is opened when the beverage bottle and the cartridge are replaced.

The lower part of the sealing door 208 is provided with a butt joint opening corresponding to the manure tray 207, a manure tray butt joint seat 209 is arranged at the butt joint opening, and a through groove corresponding to the manure tray door plate 210 is arranged on the manure tray butt joint seat 209. The faeces pan door plate 210 covers the faeces pan butt-joint seat 209, two circles of annular grooves are designed on the faeces pan butt-joint seat 209 for fixing the faeces bag, so that the faeces pan 207 bag containing faeces and urine dirt can be put in and put out, and leakage risk is reduced.

The tray door 210 opens when the tray 207 stores more dirt and the tray 207 is replaced. The arrangement of the small door 211 and the manure tray door 210 can reduce the opening times of the sealing door 208 and reduce the exposure times of the experiment operator to the infected animals. In addition, be equipped with the excrement dish docking seat 209 in the sealing door 208 main part still, the design has two circles recesses on the excrement dish docking seat 209 for fixed filth bag, this can realize containing the excrement dish bag of excrement urine filth and go into the bag out, reduces the risk of revealing.

Referring to fig. 7-8, the urinary catheterization board 206 in this embodiment includes an upper guide plate 2601 and a lower fixing plate 2602, the upper guide plate 2601 is gradually inclined downward in a direction approaching the manure tray 207, the lower fixing plate 2602 is fixed to a lower side of the upper guide plate 2061, an upper end of the lower fixing plate 2602 is connected to a side edge of the upper guide plate through a lateral connection plate 2603, and both sides of the manure tray 207 are provided to a lower side of the connection plate 2603. The connection plate 2603 and the lower fixing plate 2602 form a limit for the manure tray 207, so that the manure tray 207 can be pulled like a drawer, and the structure is simple and the operation is convenient.

When the air conditioner needs to be replaced by an independent ventilation mode, the main air inlet pipe 107, the main air outlet pipe 108, the first cabin air outlet pipe 1101, the second cabin air outlet pipe 1102, the third cabin air outlet pipe 1103, the fourth cabin air outlet pipe 1104, the first cabin air outlet pipe 1111, the second cabin air outlet pipe 1112, the third cabin air outlet pipe 1113 and the fourth cabin air outlet pipe 1114 are all opened, the electric butterfly valve 112 on the disinfection air inlet pipe 113 and the disinfection air outlet pipe 114 is all closed, and the air outlet pipe of a certain cabin can be closed according to actual requirements. When the equipment needs to be disinfected, the electric butterfly valve 112 on the disinfection inlet pipe 113 and the disinfection discharge pipe 114 are opened at the same time.

When the air intake pipe 107, the main exhaust pipe 108, the cabin air supply pipe 1101 and the electric butterfly valve 112 on the cabin air supply pipe 1111 are all opened, the cabin air supply pipe 1102, the cabin air supply pipe 1103, the cabin air supply pipe 1104 and the cabin air supply pipe 1112, the cabin air supply pipe 1113 and the electric butterfly valve 112 on the cabin air supply pipe 1114 are all closed, and the disinfection air intake pipe 113 and the electric butterfly valve 112 on the disinfection calandria 114 are all closed at the same time, so that the adjustment of the air intake mode is completed.

The above description is only a preferred embodiment of the present utility model, and is not intended to limit the utility model in any way, and any person skilled in the art may make modifications or alterations to the disclosed technical content to the equivalent embodiments. However, any simple modification, equivalent variation and variation of the above embodiments according to the technical substance of the present utility model still fall within the protection scope of the technical solution of the present utility model.

Claims (10)

1. A experimental animal negative pressure isolator with multiple ventilation modes is characterized in that: comprises a main machine (1) and combined cabin bodies (2) positioned at two sides of the main machine (1); the combined cabin body (2) is composed of a plurality of independent cabins, each cabin is respectively provided with a sealing door (208), an air inlet filter (105) and an air exhaust filter (106) are arranged in the main machine (1), each cabin of the combined cabin body (2) is respectively communicated with the air inlet filter (105) and the air exhaust filter (106), cabin air exhaust of one cabin is communicated with cabin air inlets of other cabins through a connecting pipe provided with a valve, air inlets of the air inlet filters (105) are respectively connected with a total air inlet pipe (107) and a disinfection air inlet pipe (113), and air outlets of the air exhaust filters (106) are respectively connected with a total air exhaust pipe (108) and a disinfection calandria (114).

2. The multi-ventilation-mode laboratory animal negative pressure isolator of claim 1, wherein: the upper part of the front side of each cabin of the combined cabin body (2) is provided with a cabin air inlet communicated with an air inlet filter (105), and the lower part of the rear side of each cabin is provided with a cabin air outlet communicated with an air exhaust filter (106).

3. The multi-ventilation-mode laboratory animal negative pressure isolator of claim 1, wherein: the combined cabin body (2) comprises a cabin (201), a cabin II (202), a cabin III (203) and a cabin IV (204), the outlet end of the air inlet filter (105) is connected with the cabin IV (201), the cabin II (202), the cabin III (203) and the cabin IV (204) through a cabin air supply pipe (1101), a cabin II air supply pipe (1102), a cabin III (1103) and a cabin IV (1104) respectively, and the air inlet end of the air exhaust filter (106) is connected with the cabin IV (201), the cabin IV (202), the cabin III (203) and the cabin IV (204) through a cabin IV exhaust pipe (1111), a cabin IV exhaust pipe (1112), a cabin III exhaust pipe (1113) and a cabin IV exhaust pipe (1114) respectively.

4. A multi-ventilation mode laboratory animal negative pressure isolator as claimed in claim 3, wherein: the novel sterilizing machine is characterized in that the first cabin blast pipe (1101) is provided with the second cabin blast pipe (1102), the third cabin blast pipe (1103) and the fourth cabin blast pipe (1104), the first cabin exhaust pipe (1111), the second cabin exhaust pipe (1112), the third cabin exhaust pipe (1113), the fourth cabin exhaust pipe (1114), the total air inlet pipe (107) and the total exhaust pipe (108) are respectively provided with an independent electric disc valve (112), and the sterilizing inlet pipe (113) and the sterilizing calandria (114) are respectively provided with an independent electric disc valve (112).

5. A multi-ventilation mode laboratory animal negative pressure isolator as claimed in claim 3, wherein: the connecting pipe includes No. two cabin connecting pipes (115), no. three cabin connecting pipes (116) and No. four cabin connecting pipes (117), no. one cabin exhaust pipe (1111) is connected with No. two cabin blast pipes (1102) through No. two cabin connecting pipes (115), no. one cabin exhaust pipe (1111) is connected with No. three cabin blast pipes (1103) through No. three cabin connecting pipes (116), no. one cabin exhaust pipe (1111) is connected with No. four cabin blast pipes (1104) through No. four cabin connecting pipes (117), no. two cabin connecting pipes (115), no. three cabin connecting pipes (116) and No. four cabin connecting pipes (117) are all equipped with the valve.

6. The multi-ventilation-mode laboratory animal negative pressure isolator of claim 1, wherein: the bottom of each cabin is provided with a manure tray (207) in a sliding way, the lower part of the sealing door (208) is provided with a butt joint opening corresponding to the manure tray (207), a manure tray door plate (210) is arranged at the butt joint opening, and two sides of the manure tray (207) are also provided with a urethral catheterization plate (206).

7. The multi-ventilation-mode laboratory animal negative pressure isolator of claim 6, wherein: the catheterization board (206) comprises an upper guide plate (2601) and a lower fixing plate (2602), wherein the upper guide plate (2601) is gradually and downwards inclined along the direction close to the excrement tray (207), the lower fixing plate (2602) is fixed on the lower side of the upper guide plate (2061), the upper end of the lower fixing plate (2602) is connected with the side edge of the upper guide plate through a transverse connecting plate (2603), and two sides of the excrement tray (207) are arranged on the lower side of the connecting plate (2603).

8. The multi-ventilation-mode laboratory animal negative pressure isolator of claim 1 or 6, wherein: cage frame sliding rails (205) are arranged in the middle of two sides of the inner wall of each cabin.

9. The multi-ventilation-mode laboratory animal negative pressure isolator of claim 6, wherein: the excrement tray butt joint seat (209) is also fixed at the butt joint mouth, a through groove corresponding to the excrement tray (207) is arranged on the excrement tray butt joint seat (209), the excrement tray door plate (210) is covered on the outer side of the excrement tray butt joint seat (209), and an annular groove is arranged on the excrement tray butt joint seat (209).

10. The multi-ventilation-mode laboratory animal negative pressure isolator of claim 1, wherein: the joint of the bulkheads of each cabin is of an arc structure.